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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:42 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 409–432 of 714 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-operation Pain Clear all

Conditions: Lung Cancer, Pain
Interventions: Acupuncture and Questionnaires, Placebo Acupuncture, Questionnaires; Procedure
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 162 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: New York, New York

Conditions: Post Abdominal Surgery Pain
Interventions: CR845 IV 1 mcg/kg, CR845 IV 0.5 mcg/kg, Placebo IV; Drug
Lead sponsor: Cara Therapeutics, Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 451 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 23
States / cities: Sheffield, Alabama • New Haven, Connecticut • Bradenton, Florida + 20 more

Conditions: Surgery, Upper Extremity
Interventions: Toradol, Oxycodone; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Analgesia, Obstetrical, Obstetric Surgical Procedures
Interventions: Morphine, Hydromorphone; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older · Female only
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Pain, Postoperative, Spine Injuries and Disorders, Narcotic Use
Interventions: Pre-op Multimodal analgesia (MMA) regimen + standard post-op oxycodone; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Pain
Interventions: Dexmedetomidine, Normal Saline; Drug
Lead sponsor: West Virginia University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Morbid Obesity
Interventions: IV acetaminophen, IV normal saline; Drug
Lead sponsor: McLaren Regional Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2011
U.S. locations: 1
States / cities: Flint, Michigan

Conditions: Facial Pain
Interventions: Celebrex; Drug
Lead sponsor: National Institute of Dental and Craniofacial Research (NIDCR); NIH
Eligibility: Not listed
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2004
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Knee Osteoarthritis, Knee Rheumatism
Interventions: Obturator nerve regional block, Adductor canal regional block, Saline; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 85 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Adjunctive Music Therapy in Total Knee Replacement
Interventions: Music therapy; Other
Lead sponsor: Loma Linda University; Other
Eligibility: 50 Years to 70 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Laparoscopic Surgery, Post Operative Pain, Acute, Pneumoperitoneum
Interventions: Smoke Evacuation Group, Recruitment Breath Group, Control Group; Procedure
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Cutaneous Tumors, Mohs Micrographic Surgery
Interventions: Norco 5Mg-325Mg Tablet, Suzetrigine; Drug
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years to 89 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Chronic Pain
Interventions: Ketamine plus Magnesium sulfate, Placebo; Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Post Surgical Pain
Interventions: Bupivacaine 0.25%, Dexamethasone, normal saline; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 70 Years
Enrollment: 89 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Abortion, First Trimester, Pain Management, Pain After Surgery, Satisfaction, Satisfaction With Care, Anxiety After Surgery
Interventions: VR headset, Usual Care; Device · Other
Lead sponsor: Study Investigator; Other
Eligibility: 18 Years and older · Female only
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania

Conditions: Post Tonsillectomy Pain
Interventions: Therapy dog, Costumed character, Parents-only; Behavioral
Lead sponsor: Oklahoma State University Center for Health Sciences; Other
Eligibility: 4 Years to 7 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Tulsa, Oklahoma

Conditions: Hip Surgery Corrective, Anesthesia; Functional
Interventions: Drug group Fascia iliaca nerve block, Control group sham nerve block; Procedure
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 35 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pain Measurement, Assessment, Pain
Interventions: These patients receive the Baeta device and take it home; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Surgery, Stress, Pain, Children, Post-Traumatic Stress Disorder
Interventions: Healing Touch, Healing Touch Sham Treatment; Procedure
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 3 Years to 4 Years
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Cervical Spondylosis, Lumbar Spondylosis
Interventions: Ibuprofen, normal saline; Drug · Other
Lead sponsor: St. Joseph's Hospital and Medical Center, Phoenix; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Pain
Interventions: IV acetaminophen, Placebo; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Pain, Post-operative
Interventions: Intranasal Dexmedetomidine, Intranasal Placebo; Drug
Lead sponsor: Baudax Bio; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 168 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 3
States / cities: Bakersfield, California • Pasadena, California • San Antonio, Texas

Conditions: Post-surgical Dental Pain
Interventions: Paracetamol 1000 mg, Paracetamol 650 mg, Placebo; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 401 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Neuropathic Pain
Interventions: Donepezil, Placebo; Drug
Lead sponsor: Wake Forest University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 2
States / cities: Winston-Salem, North Carolina

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Acupuncture for Post-Thoracotomy Pain

A Study Evaluating the Overall Pain Relief and Safety of Intravenous (IV) CR845 in Patients Undergoing Abdominal Surgery

Pain Control With Ketorolac and Nerve Block After Wrist and Hand Surgery

Spinal Morphine vs. Hydromorphone for Pain Control After Cesarean Delivery

An Analysis of the Efficacy of a Pre-Emptive Multimodal Pain Regimen in Reducing Acute Post-Operative Pain and Narcotic Pain Medication Requirements in Spine Surgery

Evaluation of Dexmedetomidine on Post-operative Narcotic Requirements and Pain Scores in Bariatric Patients

Efficacy of IV Acetaminophen in Acute Post-Operative Pain Control in Laparoscopic Roux-en-Y Gastric Bypass Surgery (LRYGBP) Patients

Celebrex for Pain Relief After Oral Surgery

Does Adding an Additional Numbing Medication Injection in the Thigh Help With Pain Control After Knee Replacement Surgery?

Effects of Music Listening on Pain and Patient Satisfaction Within First 48 Hours After Knee Replacment Surgery

Maneuvers to Reduce Laparoscopic Pain

Suzetrigine vs Norco-postoperative Mohs Pain

Ketamine and Magnesium in Post-operative Pain Control in Patients Treated With Opioids

Dose Response Study of Dexamethasone in Combination With Bupivacaine 0.25%

Virtual Reality as a Method for Pain and Anxiety Control During First Trimester Procedural Abortion

The Effect of Pre Surgery Dog Visits on Post Surgery Consumption of Pain Medication

Effectiveness of Fascia Iliaca Nerve Block for Post Hip Arthroscopy

Device for Monitoring Pain During Intraoperative, Pre/Post Surgical Periods: Comparison With Standard of Care Monitoring

The Effects of Healing Touch on Post Operative Pediatric Patients

Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery

Perioperative Systemic Acetaminophen to Improve Postoperative Quality of Recovery After Ambulatory Breast Surgery

Placebo-Controlled Evaluation of Intranasal Dexmedetomidine for Postoperative Analgesia Following Bunionectomy Surgery

Post-operative Dental Pain Study Comparing Two Different Dosage of Analgesic Efficacy

Donepezil Compared to Placebo in Patients With Chronic Neuropathic Pain