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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Postoperative Atrial Fibrillation Clear all
Completed Phase 2Phase 3 Interventional Results available

Renin-angiotensin-aldosterone System (RAAS), Inflammation, and Post-Operative Atrial Fibrillation (AF)

NCT00141778
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Placebo, Ramipril, Spironolactone
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 80 Years
Enrollment
455 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 21, 2013 · Synced Jun 10, 2026, 9:32 PM EDT
Completed Not applicable Interventional Results available

Tragus Stimulation to Prevent Atrial Fibrillation After Cardiac Surgery

NCT03392649
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Parasym
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 89 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 3, 2022 · Synced Jun 10, 2026, 9:32 PM EDT
Recruiting No phase listed Observational

Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery

NCT05014802
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Arrhythmia, Atrial Flutter, Atrial Tachycardia
Interventions
Not listed
Lead sponsor
Tulane University
Other
Eligibility
40 Years to 120 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
Covington, Louisiana • New Orleans, Louisiana • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jun 10, 2026, 9:32 PM EDT
Completed Phase 1 Interventional

Vitamin C in Cardiac Surgery Patients

NCT03123107
View directory record Official record
Conditions
Coronary Artery Bypass Graft Surgery
Interventions
Ascorbic Acid
Drug
Lead sponsor
Geisinger Clinic
Other
Eligibility
21 Years to 79 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Wilkes-Barre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 15, 2021 · Synced Jun 10, 2026, 9:32 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Temporary Autonomic Blockade to Prevent Atrial Fibrillation After Cardiac Surgery

NCT02498769
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Botulinum Toxin Type A, Placebo
Drug
Lead sponsor
Joseph Mathew, M.D.
Other
Eligibility
50 Years to 90 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 21, 2019 · Synced Jun 10, 2026, 9:32 PM EDT
Withdrawn Phase 1Phase 2 Interventional

Safety and Efficacy Study of Amniotic Membrane Patch to Treat Postoperative Atrial Fibrillation

NCT02193321
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Amniotic Membrane Patch
Biological
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 1, 2015 · Synced Jun 10, 2026, 9:32 PM EDT
Recruiting Phase 3 Interventional

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

NCT04045665
View directory record Official record
Conditions
Atrial Fibrillation, Stroke, Bleeding
Interventions
Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
3,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
51
States / cities
Little Rock, Arkansas • Los Angeles, California • Stanford, California + 40 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Jun 10, 2026, 9:32 PM EDT
Terminated Phase 3 Interventional Results available

Suppression Of Atrial Fibrillation With Ranolazine After Cardiac Surgery

NCT01352416
View directory record Official record
Conditions
Heart; Dysfunction Postoperative, Cardiac Surgery
Interventions
Ranolazine, Placebo
Drug
Lead sponsor
Corewell Health East
Other
Eligibility
22 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Royal Oak, Michigan • Troy, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 5, 2017 · Synced Jun 10, 2026, 9:32 PM EDT
Recruiting Not applicable Interventional

Pericardiotomy in Cardiac Surgery

NCT06486636
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter, Cardiac Events
Interventions
Left Posterior Pericardiotomy
Procedure
Lead sponsor
Population Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
1,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 13, 2025 · Synced Jun 10, 2026, 9:32 PM EDT
Terminated No phase listed Observational

Cardiac Monitoring of Post-Operative Cancer Patients Experiencing Atrial Fibrillation

NCT01253590
View directory record Official record
Conditions
Post-Operative Cancer Patients Experiencing Atrial, Fibrillation
Interventions
questionnaire about the use of ECG device
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
22 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 5, 2015 · Synced Jun 10, 2026, 9:32 PM EDT
Completed No phase listed Observational

Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys

NCT02032030
View directory record Official record
Conditions
Heart Attack, Cardiac Arrest, Congestive Heart Failure, Atrial Fibrillation, Angina, Deep Vein Thrombosis, Pulmonary Embolism, Respiratory Arrest, Respiratory Failure, Pneumonia, Gastrointestinal Bleed, Stomach Ulcer, Delirium, Stroke, Nerve Injury, Surgical Wound Infection
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
73,952 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Jun 10, 2026, 9:32 PM EDT
Recruiting Phase 1Phase 2 Interventional

Anthocyanin-Rich Table Grape Powder for Prophylaxis of Post-Operative Atrial Fibrillation

NCT05991700
View directory record Official record
Conditions
Post-operative Atrial Fibrillation (POAF)
Interventions
Freeze-Dried California Table Grape, Placebo
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 79 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Jun 10, 2026, 9:32 PM EDT
Withdrawn Phase 4 Interventional

Study to Evaluate the Effectiveness of SGB in Preventing Post-op Atrial Fibrillation

NCT03269383
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Bupivacaine, Saline
Drug · Other
Lead sponsor
Christopher Connors, MD
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated Apr 23, 2019 · Synced Jun 10, 2026, 9:32 PM EDT
Terminated Not applicable Interventional

Transcutaneous Autonomic Modulation in Thoracic Surgery

NCT02783157
View directory record Official record
Conditions
Atrial Fibrillation, Postoperative, Postoperative Complications, Inflammation
Interventions
Transcutaneous Low-Level Vagal Nerve Stimulation (LLVNS), Sham LLVNS
Device
Lead sponsor
Duke University
Other
Eligibility
40 Years to 90 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 5, 2020 · Synced Jun 10, 2026, 9:32 PM EDT
Completed Phase 4 Interventional Results available

AtriClip® Left Atrial Appendage Exclusion Concomitant to Structural Heart Procedures (ATLAS)

NCT02701062
View directory record Official record
Conditions
Post-Operative Atrial Fibrillation
Interventions
AtriClip® Gillinov-Cosgrove™ LAA Exclusion Systems, Anticoagulation Therapy
Device · Drug
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years and older
Enrollment
562 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
22
States / cities
San Diego, California • Stanford, California • Orlando, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Jun 10, 2026, 9:32 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Apixaban Versus Warfarin for the Management of Post-operative Atrial Fibrillation

NCT02889562
View directory record Official record
Conditions
Coronary Artery Bypass Grafting, Postoperative Atrial Fibrilation, Stroke, Systemic Embolism, Deep Venous Thrombosis
Interventions
Apixaban, Warfarin
Drug
Lead sponsor
Sanford Health
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Jan 21, 2021 · Synced Jun 10, 2026, 9:32 PM EDT
Completed Not applicable Interventional Results available

Evaluation Of New Onset Postoperative Atrial Fibrillation

NCT01247974
View directory record Official record
Conditions
Atrial Fibrillation New Onset
Interventions
CorMatrix ECM for Pericardial Closure
Device
Lead sponsor
Elutia Inc.
Industry
Eligibility
18 Years and older
Enrollment
439 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
16
States / cities
Birmingham, Alabama • Dothan, Alabama • Mobile, Alabama + 12 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Jun 10, 2026, 9:32 PM EDT
Completed Not applicable Interventional

Transcutaneous (Tragus) Vagal Nerve Stimulation for Post-op Afib

NCT04514757
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
active tVNS, sham tVNS
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 80 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Los Angeles, California • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Feb 23, 2025 · Synced Jun 10, 2026, 9:32 PM EDT
Recruiting No phase listed Observational

Quality of Life in Patients With Postoperative Atrial Fibrillation After Cardiac Surgery

NCT07173998
View directory record Official record
Conditions
Postoperative Atrial Fibrillation
Interventions
Survey
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
260 participants
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Jun 10, 2026, 9:32 PM EDT
Completed No phase listed Observational

Genomics and Postoperative Atrial Fibrillation

NCT00280163
View directory record Official record
Conditions
Postoperative Atrial Fibrillation, Genomics
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 11, 2016 · Synced Jun 10, 2026, 9:32 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Pilot-Tart Cherry, Mitral Transcriptome, and POAF Incidence

NCT03793465
View directory record Official record
Conditions
Post-operative Atrial Fibrillation (POAF)
Interventions
tart cherry concentrate
Dietary Supplement
Lead sponsor
University of Michigan
Other
Eligibility
50 Years to 79 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Jun 10, 2026, 9:32 PM EDT
Recruiting Phase 2 Interventional

Amiodarone for the Prevention of Atrial Fibrillation After Minimally Invasive Esophagectomy in Patients With Esophageal Cancer

NCT06067438
View directory record Official record
Conditions
Atrial Fibrillation, Esophageal Carcinoma
Interventions
Amiodarone Hydrochloride, Saline
Drug · Other
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jun 10, 2026, 9:32 PM EDT
Recruiting Early Phase 1 Interventional

Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone

NCT06063538
View directory record Official record
Conditions
Atrial Fibrillation, Post-Op Complication
Interventions
CardiaMend in Combination with Amiodarone
Combination Product
Lead sponsor
University of Chicago
Other
Eligibility
20 Years to 85 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Jun 10, 2026, 9:32 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

BoxX-NoAF Clinical Trial

NCT06989775
View directory record Official record
Conditions
Post Operative Atrial Fibrillation, Atrial Fibrillation, Postoperative
Interventions
Isolator® Synergy™ EnCompass® Ablation System and AtriClip® LAA Exclusion System
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
65 Years and older
Enrollment
960 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
14
States / cities
Jonesboro, Arkansas • Clearwater, Florida • Orlando, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jun 10, 2026, 9:32 PM EDT