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ClinicalTrials.gov public records Last synced Oct 8, 2026, 9:29 PM EDT

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Showing 361–384 of 1,255 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Posttraumatic Stress Disorder PTSD Clear all
Completed No phase listed Observational

Effectiveness and Acceptability of Stellate Ganglion Block for Posttraumatic Stress Disorder Symptoms - Acceptability

NCT03302312
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Not listed
Lead sponsor
RTI International
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Honolulu, Hawaii • Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 30, 2018 · Synced Oct 8, 2026, 9:29 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Imaging Phosphodiesterase 4B (PDE4B) in People With Psychiatric Disorders With Positron Emission Tomography (PET) and the Radiotracer [18F]PF974

NCT07488819
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, PTSD, Alcohol Use Disorder (AUD)
Interventions
PF974
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2032
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

Compassion Meditation for PTSD

NCT02372396
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Compassion Meditation (CM), Relaxation
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 5, 2018 · Synced Oct 8, 2026, 9:29 PM EDT
Withdrawn Phase 2Phase 3 Interventional

Groups for Regaining Our Wellbeing (GROW)

NCT01971541
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression
Interventions
Mindfulness-Based Stress Reduction, Cognitive Processing Therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 2, 2014 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Early Abuse on Adult Intimate Relationships

NCT01803802
View directory record Official record
Conditions
Hypoactive Sexual Desire Disorder, Female Sexual Arousal Disorder, Female Orgasmic Disorder, Major Depressive Disorder, Post-traumatic Stress Disorder
Interventions
Expressive writing
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older · Female only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2014
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Phase 2 Interventional Results available

A Study of Flexible Dose Brexpiprazole as Monotherapy or Combination Therapy in the Treatment of Adults With Post-traumatic Stress Disorder (PTSD)

NCT03033069
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Brexpiprazole, Sertraline, Brexpiprazole Matching Placebo, Sertraline Matching Placebo
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
54
States / cities
Tuscaloosa, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 48 more
Source: ClinicalTrials.gov public record
Updated Dec 8, 2021 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional

Cognitive Processing Intervention for Trauma, HIV/STI Risks, and Substance Use Among Native Women

NCT01849029
View directory record Official record
Conditions
Post Traumatic Stress Disorders, Unsafe Sex, Substance Use Disorders
Interventions
Cognitive Processing Therapy-Cognitive
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Toppenish, Washington
Source: ClinicalTrials.gov public record
Updated Aug 22, 2017 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

Effectiveness of Three Different Psychotherapies for Chronic Post-Traumatic Stress Disorder

NCT00739765
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Interpersonal Psychotherapy, Prolonged Exposure Therapy, Relaxation Therapy
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional

Brief Cognitive Behavioral Treatment of Deployment-Related PTSD Symptoms in Primary Care Settings

NCT02290639
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Brief Cognitive Behavioral Treatment, Minimal Contact
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Lackland Air Force Base, Texas • Randolph Air Force Base, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2016 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional

The Role of Exercise in the Treatment of PTSD Symptoms

NCT02649127
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
imaginal therapy, exercise, self-care
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Sep 11, 2017 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking

NCT03488927
View directory record Official record
Conditions
Social Skills, Self-Criticism, Post-traumatic Stress Disorder, Depression, Alcohol Abuse, Drinking, College, Alcohol Drinking, Alcohol; Harmful Use, Social Stigma, Social Norms, Social Responsibility, Social Behavior, Empathy, Coping Skills, Coping Behavior
Interventions
Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS)
Behavioral
Lead sponsor
University of New Hampshire
Other
Eligibility
18 Years to 24 Years
Enrollment
1,268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya

NCT01822366
View directory record Official record
Conditions
Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms, Behavioral Problems, Child Overall Daily Functioning, Child and Guardian Relationship
Interventions
Trauma-focused Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Duke University
Other
Eligibility
7 Years to 13 Years
Enrollment
1,280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 5, 2021 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Mindfulness Based Cognitive Therapy (MBCT) Resiliency Program for Critical Care Nurses

NCT03132220
View directory record Official record
Conditions
Burn-Out Syndrome, Work-Related Stress Disorder
Interventions
Mindfulness-Based Cognitive Therapy, Book Club Active Control Intervention
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 9, 2019 · Synced Oct 8, 2026, 9:29 PM EDT
Terminated Phase 4 Interventional Results available

Perioperative Propranolol in Patients With Post Traumatic Stress Disorder (PTSD)

NCT01555554
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Propranolol Hydrochloride, Placebo
Drug · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
40 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional

Efficacy of Evidence-Based PTSD Treatment Via Prebiotic Supplementation

NCT05424146
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Prebiotic Bar +CPT, Non-Prebiotic Bar +CPT
Dietary Supplement · Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Oct 8, 2026, 9:29 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Receptor Function in Post-Traumatic Stress Disorder

NCT00046553
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
RU-486 (Mifepristone)
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Phase 2 Interventional

An Evaluation of the Long-term Efficacy and Safety of Methylone for the Treatment of PTSD

NCT06237426
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Methylone
Drug
Lead sponsor
Transcend Therapeutics
Industry
Eligibility
18 Years to 71 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Denver, Colorado • Rockville, Maryland • Draper, Utah
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 8, 2026, 9:29 PM EDT
Recruiting Not applicable Interventional

Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms

NCT05414708
View directory record Official record
Conditions
PTSD, Military Activity, Post-Traumatic Headache, Posttraumatic Stress Disorder, Posttraumatic Stress Disorder, Delayed Onset, Sleep Disturbance, Nightmare, Irritable Mood, Anger, Combat and Operational Stress Reaction, Combat Stress Disorders, Military Family, Military Operations, Emotional Regulation, Emotion Processing
Interventions
Art Therapy
Behavioral
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 64 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 8, 2026, 9:29 PM EDT
Terminated Phase 3 Interventional

SSRI Administration to Reduce Acute Stress Disorder Symptoms and Prevent Depression and PTSD in Physical Trauma Victims

NCT00114374
View directory record Official record
Conditions
Anxiety Disorder
Interventions
Escitalopram
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 9, 2014 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional

Treating Post Traumatic Stress Disorder in Children Exposed to Domestic Violence

NCT00183326
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Anxiety, Depression
Interventions
Trauma-focused cognitive behavioral therapy (TF-CBT), Child-centered supportive therapy (CCT)
Behavioral
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
7 Years to 14 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Oct 8, 2026, 9:29 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Hydrocortisone in Patients With Post-Traumatic Stress Disorder

NCT00039715
View directory record Official record
Conditions
Post-Traumatic Stress Disorders, Healthy
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional

Group Cognitive Processing Therapy for Combat-related Posttraumatic Stress Disorder (PTSD)

NCT01286415
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Group Cognitive Processing Therapy-Cognitive Only, Group Present Centered Therapy
Behavioral
Lead sponsor
VA Boston Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Oct 8, 2026, 9:29 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effectiveness of a Web-based Intervention for Guardians of Children Whose One Parent Has Murdered the Other

NCT00737035
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Interactive Healthcare Communication Application, Control Web sites
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 7, 2015 · Synced Oct 8, 2026, 9:29 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Ketamine as a Treatment for Post-Traumatic Stress Disorder (PTSD)

NCT02397889
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Ketamine, Midazolam
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 11, 2021 · Synced Oct 8, 2026, 9:29 PM EDT