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Showing 1–24 of 1,246 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Posttraumatic Stress Disorders Clear all
Not listed Phase 3 Interventional

Transcranial Magnetic Stimulation (TMS) for Suicidal Ideation

NCT01212848
View directory record Official record
Conditions
Depressive Episode, Posttraumatic Stress Disorder, Traumatic Brain Injury
Interventions
Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation - Sham Comparator
Device
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Bethesda, Maryland • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2013 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

PPG Project 3 - PET/MRI of the Brain-hematopoiesis-atherosclerosis Axis in PTSD Patients

NCT03279393
View directory record Official record
Conditions
PTSD, Trauma, Healthy
Interventions
fluorodeoxyglucose (FDG)-PET/MRI
Drug
Lead sponsor
Zahi Fayad
Other
Eligibility
30 Years to 65 Years
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Phase 1 Interventional

A Dose Escalation Study of Intranasal Neuropeptide Y in Post Traumatic Stress Disorder (PTSD)

NCT01533519
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Neuropeptide Y
Drug
Lead sponsor
James Murrough
Other
Eligibility
18 Years to 60 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2016 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Not applicable Interventional

Clinical Effectiveness Trial of In-Home Cognitive Processing Therapy for Combat-Related PTSD

NCT02290847
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD
Interventions
Cognitive Processing Therapy (cognitive only version; CPT-C)
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 3, 2020 · Synced Jul 21, 2026, 4:04 PM EDT
Completed No phase listed Observational

Examining the Role of Negative Emotional States on Sedative Drug Use in Individuals With Post-Traumatic Stress Disorder

NCT00244335
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 60 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2008
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 9, 2017 · Synced Jul 21, 2026, 4:04 PM EDT
Recruiting No phase listed Observational

NYSCF Scientific Discovery Biobank

NCT06203106
View directory record Official record
Conditions
ALS, Amyotrophic Lateral Sclerosis, Alzheimer Disease, Alzheimer Disease, Early Onset, Alzheimer Disease, Late Onset, Batten Disease, Corticobasal Degeneration, Dementia, Frontotemporal Dementia, Huntington Disease, Lewy Body Disease, Multiple Sclerosis, Multiple System Atrophy, Parkinson Disease, Parkinson's Disease and Parkinsonism, Progressive Supranuclear Palsy, INAD, Diabetes, Diabetes Mellitus, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Macular Degeneration, Ovarian Cancer, Cervical Cancer, Uterine Cancer, Vaginal Cancer, Vulvar Cancer, PTSD, Post Traumatic Stress Disorder
Interventions
Biological Sample Collection
Other
Lead sponsor
New York Stem Cell Foundation Research Institute
Other
Eligibility
30 Days and older
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2045
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2025 · Synced Jul 21, 2026, 4:04 PM EDT
Active, not recruiting Phase 1 Interventional

A Study of Psilocybin for PTSD

NCT06407635
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Psilocybin, Trauma-focused psychotherapy, Standard psychological support
Drug · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Psychosocial Functioning in Older Veterans With PTSD

NCT02803125
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Psychosocial intervention, Support group control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 31, 2024 · Synced Jul 21, 2026, 4:04 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Approach-Avoidance and Alcohol Challenge Study in PTSD

NCT06002633
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Alcohol Drinking
Interventions
Alcohol, Placebo
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
21 Years to 60 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Phase 2 Interventional

Cognitive Behavioral Therapy for Post Traumatic Stress Disorder in Addiction Treatment

NCT01456338
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Substance-Related Disorders
Interventions
Cognitive Behavioral Therapy for PTSD, Individual Addiction Counseling
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
6
States / cities
Hartford, Connecticut • Lebanon, New Hampshire • Manchester, New Hampshire + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2011 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Geodon (Ziprasidone) for Posttraumatic Stress Disorder

NCT00208208
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Post-Traumatic Stress Disorder, PTSD
Interventions
Ziprasidone
Drug
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 64 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 14, 2006 · Synced Jul 21, 2026, 4:04 PM EDT
Recruiting Not applicable Interventional

Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms

NCT05414708
View directory record Official record
Conditions
PTSD, Military Activity, Post-Traumatic Headache, Posttraumatic Stress Disorder, Posttraumatic Stress Disorder, Delayed Onset, Sleep Disturbance, Nightmare, Irritable Mood, Anger, Combat and Operational Stress Reaction, Combat Stress Disorders, Military Family, Military Operations, Emotional Regulation, Emotion Processing
Interventions
Art Therapy
Behavioral
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 64 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Jul 21, 2026, 4:04 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Risk Prediction for Alzheimer Dementia With Brain Imaging and Genetics

NCT03641768
View directory record Official record
Conditions
Alzheimer Dementia, Posttraumatic Stress Disorder, Traumatic Brain Injury
Interventions
MRI, PET, 18F-Florbetapir, Radioligand 18F-AV-1451
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Jul 21, 2026, 4:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Treatment of Comorbid Sleep Disorders and Post Traumatic Stress Disorder (PTSD)

NCT02773693
View directory record Official record
Conditions
Trauma, Insomnia, Nightmares
Interventions
Cognitive Processing Therapy-Cognitive Only (CPT), Cognitive Behavioral Therapy of Insomnia and Nightmares (CBTin), Continuation Cognitive Processing Therapy-Cognitive Only (CPT)
Behavioral
Lead sponsor
University of North Texas, Denton, TX
Other
Eligibility
18 Years to 50 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Sep 26, 2018 · Synced Jul 21, 2026, 4:04 PM EDT
Recruiting Not applicable Interventional

Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD

NCT07238192
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Suicidal Ideation, Suicide Attempt
Interventions
Cognitive Processing Therapy
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder

NCT00118534
View directory record Official record
Conditions
Mental Health, Stress Disorders, Post-Traumatic, Substance-Related Disorders, Tobacco Use Disorder
Interventions
Integrated Care for Smoking Cessation in PTSD patients, Standard of Care
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 80 Years
Enrollment
943 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
11
States / cities
Tuscaloosa, Alabama • San Diego, California • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated May 4, 2014 · Synced Jul 21, 2026, 4:04 PM EDT
Recruiting Not applicable Interventional

Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the Course

NCT06957067
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
CPT Skills, Cognitive Processing Therapy, Present Centered Therapy, Shared Decision Making, Measurement Based Care
Behavioral
Lead sponsor
United States Department of Defense
Federal
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
Phoenix, Arizona • New Orleans, Louisiana • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bounce Back Now: A Low-Cost Intervention to Facilitate Post-Disaster Recovery

NCT03403738
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Bounce Back Now, enhanced usual care
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
1,357 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Jul 21, 2026, 4:04 PM EDT
Recruiting No phase listed Observational

The Effects of Stellate Ganglion Block Sleep in U.S. Active Duty Service Members and Veterans Receiving Prolonged Exposure Therapy for PTSD

NCT07667309
View directory record Official record
Conditions
Post Traumatic Stress Disorder PTSD
Interventions
Sleep Profiler Headband
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Killeen, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Not applicable Interventional Results available

rTMS for PTSD Comorbid With Major Depressive Disorder

NCT02273063
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Major Depressive Disorder, Transcranial Magnetic Stimulation, Repetitive
Interventions
Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Jul 21, 2026, 4:04 PM EDT
Withdrawn Not applicable Interventional

Hydrocortisone for Prevention of Post-Traumatic Stress Disorder

NCT02402114
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Hydrocortisone
Drug
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Not applicable Interventional Results available

Treatment of Older Veterans With Chronic Posttraumatic Stress Disorder

NCT00539279
View directory record Official record
Conditions
Combat Disorders, Post-traumatic Stress Disorder
Interventions
Prolonged Exposure Therapy (PE), Relaxation Training (RT)
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
60 Years and older · Male only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2015 · Synced Jul 21, 2026, 4:04 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Kappa Opioid Receptor Imaging in Post-traumatic Stress Disorder (PTSD)

NCT02237703
View directory record Official record
Conditions
Post-traumatic Stress Disorder (PTSD), Trauma
Interventions
Positron emission tomography (PET) imaging
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 55 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced Jul 21, 2026, 4:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

AI to Support Mental Health Case Management Providers

NCT06280170
View directory record Official record
Conditions
Depressive Disorder, Anxiety Disorders, Substance Use Disorders, Post Traumatic Stress Disorder
Interventions
Artificial Intelligence platform for case managers
Other
Lead sponsor
Eleos Health
Industry
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Alton, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 27, 2024 · Synced Jul 21, 2026, 4:04 PM EDT