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Showing 1–24 of 1,247 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Posttraumatic Stress Disorders Clear all
Completed Not applicable Interventional

Treatment for Women With Post-Traumatic Stress Disorder Related to Childhood Abuse

NCT00069381
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Psychotherapy treatment
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
22 Years to 65 Years · Female only
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 28, 2013 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Cognitive Behavioral Therapy and Yoga Program for Trauma Symptoms

NCT02368444
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cognitive Behavioral Therapy and Yoga
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Jul 23, 2026, 6:16 PM EDT
Recruiting Not applicable Interventional

Novel Telemedicine-Delivered Prolonged Exposure Therapy for Treating PTSD in Individuals With OUD

NCT06288711
View directory record Official record
Conditions
Opioid Use Disorder, Posttraumatic Stress Disorder
Interventions
Prolonged exposure therapy, Financial incentives, Treatment as usual
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Jul 23, 2026, 6:16 PM EDT
Active, not recruiting Not applicable Interventional

Open Pilot Trial of Adapted Cognitive Processing Therapy for Comorbid PTSD and Opioid Use Disorder

NCT06872164
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Opioid Use Disorder
Interventions
Cognitive Processing Therapy
Behavioral
Lead sponsor
The City College of New York
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Phase 4 Interventional

An Open-Label Trial of Memantine for Cognitive Impairment in Patients With Post-Traumatic Stress Disorder

NCT02258828
View directory record Official record
Conditions
PTSD
Interventions
Memantine, Placebo
Drug
Lead sponsor
Sriram Ramaswamy
Federal
Eligibility
19 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated May 21, 2020 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brief Treatment for Posttraumatic Stress Disorder

NCT03033602
View directory record Official record
Conditions
PTSD
Interventions
written exposure therapy, CPT, cognitive only
Behavioral
Lead sponsor
Boston VA Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
2
States / cities
Killeen, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Not applicable Interventional

Reminder Focused Positive Psychiatry in Adolescents With ADHD and PTSD

NCT04336072
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Attention Deficit Hyperactivity Disorder
Interventions
RFPP, TFCBT
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
9 Years to 18 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Not applicable Interventional Results available

Attention-Bias Modification Treatment for PTSD

NCT01888653
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Attention Bias Modification (ABM), Attention control training (ACT)
Behavioral
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2022 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Not applicable Interventional

Technology and Telephone-Based Smoking Cessation

NCT03492645
View directory record Official record
Conditions
Smoking Cessation
Interventions
Telephone-and technology-facilitated treatment protocol, Office-based treatment protocol
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 69 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2019 · Synced Jul 23, 2026, 6:16 PM EDT
Recruiting Not applicable Interventional

Multifaceted Intervention to Restore Resilience and Overcome Risk

NCT06988787
View directory record Official record
Conditions
Military Sexual Trauma, Intimate Partner Violence, Brain Injury, Post Traumatic Stress Disorder
Interventions
webSTAIR, ExpoTx, PsychoEd
Behavioral · Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neurobiological and Psychological Benefits of Exercise in Chronic Pain and PTSD

NCT03283163
View directory record Official record
Conditions
Chronic Musculoskeletal Pain, Posttraumatic Stress Disorder (PTSD), Mild or Moderate Traumatic Brain Injury
Interventions
Exercise Testing and Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2024 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Not applicable Interventional

Brief Exposure and Exercise for PTSD.

NCT07080606
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder
Interventions
Brief exposure therapy and exercise
Behavioral
Lead sponsor
Troy Hubert
Other
Eligibility
18 Years to 64 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Not applicable Interventional Results available

Piloting "Signs of Safety": A Deaf-Accessible Therapy Toolkit for Alcohol Use Disorder and Trauma

NCT03845985
View directory record Official record
Conditions
Alcohol Use Disorder, Post Traumatic Stress Disorder
Interventions
Seeking Safety + Signs of Safety toolkit
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Not applicable Interventional

Restoring Emotional, Sexual, and Physical Empowerment Through CBT & Trauma-sensitive Care: A Chronic Pelvic Pain Intervention

NCT02588885
View directory record Official record
Conditions
Pelvic Pain, Stress Disorders, Traumatic
Interventions
Trauma-sensitive Care
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Jul 23, 2026, 6:16 PM EDT
Recruiting Not applicable Interventional

Multimodal Image Analysis and Guidance of Neuromodulation for Trauma-Related Symptoms

NCT06449326
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Active Intermittent theta burst stimulation, Sham Intermittent theta burst stimulation
Device
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 80 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 23, 2026, 6:16 PM EDT
Completed No phase listed Observational

Long-Term Survival With HIV: Psychological and Behavioral Factors Associated With the Transition From Adolescence to Young Adulthood

NCT00026806
View directory record Official record
Conditions
HIV Infection
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 23, 2026, 6:16 PM EDT
Recruiting Not applicable Interventional

OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit

NCT05156112
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Obstructive Sleep Apnea, Substance Use Disorder, Residential Treatment Program
Interventions
Positive Airway Pressure Device
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Not applicable Interventional

Cognitive Behavioral Treatment for Post-Traumatic Stress Disorder in People With Additional Serious Mental Illnesses

NCT00494650
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Cognitive behavioral therapy (CBT), Brief PTSD treatment
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
5
States / cities
Monmouth Junction, New Jersey • New Brunswick, New Jersey • Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 7, 2012 · Synced Jul 23, 2026, 6:16 PM EDT
Recruiting Not applicable Interventional

Enhancing PTSD Treatment Outcomes by Improving Patient-Provider Communication

NCT06088303
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Adjunctive writing to amplify response and engagement (AWARE), Cognitive processing therapy (CPT), Prolonged exposure (PE)
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking

NCT03488927
View directory record Official record
Conditions
Social Skills, Self-Criticism, Post-traumatic Stress Disorder, Depression, Alcohol Abuse, Drinking, College, Alcohol Drinking, Alcohol; Harmful Use, Social Stigma, Social Norms, Social Responsibility, Social Behavior, Empathy, Coping Skills, Coping Behavior
Interventions
Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS)
Behavioral
Lead sponsor
University of New Hampshire
Other
Eligibility
18 Years to 24 Years
Enrollment
1,268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Not applicable Interventional Results available

Group CBT for Aggression in Veterans

NCT02233517
View directory record Official record
Conditions
Aggression, Anger, Posttraumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy, Present Centered Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Mindfulness Based Cognitive Therapy (MBCT) Resiliency Program for Critical Care Nurses

NCT03132220
View directory record Official record
Conditions
Burn-Out Syndrome, Work-Related Stress Disorder
Interventions
Mindfulness-Based Cognitive Therapy, Book Club Active Control Intervention
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 8, 2019 · Synced Jul 23, 2026, 6:16 PM EDT
Completed Phase 2 Interventional Results available

Ketamine as a Rapid Treatment for Post-traumatic Stress Disorder (PTSD)

NCT00749203
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, PTSD, Depression, Anxiety Disorder
Interventions
Midazolam, Ketamine
Drug
Lead sponsor
Dennis Charney
Other
Eligibility
21 Years to 55 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Jul 23, 2026, 6:16 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in PTSD.

NCT07079761
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Experiment 1. Three-day aversive conditioning, extinction, and extinction retention testing paradigm, Allopregnanolone (Allo) with 6% USP Dexolve (sulfobutyl ether-beta-cyclodextrin sodium salt) in 0.9% saline for IV infusion will be provided by the University of California, Davis, GMP manufacturer., Matching IV Placebo, Experiment 2. Three-day aversive conditioning, reconsolidation blockade, and testing paradigm
Behavioral · Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Jul 23, 2026, 6:16 PM EDT