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Showing 1–24 of 361 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pre-hypertension Clear all
Terminated Phase 4 Interventional Results available

The Effect of Two Aspirin Dosing Strategies for Obese Women at High Risk for Preeclampsia

NCT03735433
View directory record Official record
Conditions
Preeclampsia
Interventions
162mg aspirin dose
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 28, 2024 · Synced Sep 5, 2026, 9:01 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

PLAC1 in Reproduction

NCT01277848
View directory record Official record
Conditions
Pregnancy
Interventions
Not listed
Lead sponsor
University of South Florida
Other
Eligibility
14 Years to 55 Years · Female only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 25, 2017 · Synced Sep 5, 2026, 9:01 PM EDT
Not listed Not applicable Interventional

Clinical Trial to Assess the Effects of Low-fat Dairy on Systolic Blood Pressure

NCT01463085
View directory record Official record
Conditions
Hypertension
Interventions
Low-fat dairy
Other
Lead sponsor
Dairy Research Institute
Other
Eligibility
20 Years to 69 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Glen Ellyn, Illinois
Source: ClinicalTrials.gov public record
Updated May 23, 2012 · Synced Sep 5, 2026, 9:01 PM EDT
Completed No phase listed Observational

Total Health Improvement Program Research Project

NCT04082585
View directory record Official record
Conditions
Chronic Disease, Cardiovascular Diseases, Hypertension, Diabetes, Pre-diabetes, Obesity
Interventions
Total Health Improvement Program
Behavioral
Lead sponsor
Pacific Northwest University of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Roseburg, Oregon
Source: ClinicalTrials.gov public record
Updated May 8, 2022 · Synced Sep 5, 2026, 9:01 PM EDT
Recruiting Not applicable Interventional

A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

NCT07214376
View directory record Official record
Conditions
Pulmonary Hypertension, Heart Failure With Reduced Ejection Fraction, Hypertension, Vascular Diseases, Cardiovascular Diseases, Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction
Interventions
Pulmonary Artery Denervation (PADN), Sham procedure control
Device
Lead sponsor
Pulnovo Medical, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
6
States / cities
Tucson, Arizona • Houma, Louisiana • Detroit, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Magnesium Sulfate in Obese Preeclamptics

NCT02835339
View directory record Official record
Conditions
Preeclampsia
Interventions
Magnesium sulfate 4g loading dose, 1g/hr infusion, Magnesium sulfate 6g loading dose, 2g/hr infusion
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Sep 5, 2026, 9:01 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Alterations in the Plasma Proteome of Early-Onset Severe Preeclampsia

NCT00719654
View directory record Official record
Conditions
Preeclampsia
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
Female only
Enrollment
316 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 17, 2018 · Synced Sep 5, 2026, 9:01 PM EDT
Completed No phase listed Observational

Thromboelastogram in Postdelivery Preeclamptic Patients

NCT03555630
View directory record Official record
Conditions
Preeclampsia, Coagulation Disorder, Pregnancy Complications
Interventions
Thromboelastogram
Diagnostic Test
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 23, 2020 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Not applicable Interventional

Mindfulness-Based Blood Pressure Reduction: Stage 2a RCT

NCT03256890
View directory record Official record
Conditions
Hypertension, Prehypertension
Interventions
MB-BP Intervention, Enhanced Usual Care Control
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Sep 5, 2026, 9:01 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Gene Expression In Pregnancies Complicated by Preeclampsia

NCT00919360
View directory record Official record
Conditions
Preeclampsia
Interventions
collection of maternal blood specimen prior to delivery, collection of placental cord blood after delivery, collection of placental tissue, collection of strip of decidua from uterine lining from cesarean section deliveries
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older · Female only
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 20, 2015 · Synced Sep 5, 2026, 9:01 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Predicitve Use of Spot Urine Protein/Creatinine Ratios in Preeclampsia

NCT00870428
View directory record Official record
Conditions
Preeclampsia
Interventions
Not listed
Lead sponsor
MemorialCare
Other
Eligibility
18 Years and older · Female only
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2009 · Synced Sep 5, 2026, 9:01 PM EDT
Active, not recruiting No phase listed Observational

Use of a Cloud-connected Remote Blood Pressure Monitoring Program During the Postpartum Period for Hypertensive Women

NCT06096701
View directory record Official record
Conditions
Hypertensive Disorder
Interventions
Blood pressure cuff
Device
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 54 Years · Female only
Enrollment
421 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 5, 2026, 9:01 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

162 mg of Aspirin for Prevention of Preeclampsia

NCT05221164
View directory record Official record
Conditions
Preeclampsia
Interventions
Aspirin 162 mg
Drug
Lead sponsor
Methodist Medical Center of Illinois
Other
Eligibility
Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 1, 2022 · Synced Sep 5, 2026, 9:01 PM EDT
Terminated Phase 2 Interventional Results available

Safety and Efficacy of RLX030 in Pregnant Women With Pre- Eclampsia

NCT01566630
View directory record Official record
Conditions
Pre-eclampsia
Interventions
Placebo, RLX030
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
4
States / cities
Mobile, Alabama • Lexington, Kentucky • Louisville, Kentucky + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 4, 2015 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Not applicable Interventional

Virtual Reality as a Tool to Lower Blood Pressure and Anxiety in Clinic Settings

NCT06960057
View directory record Official record
Conditions
White Coat Hypertension, Hypertension, Blood Pressure, Anxiety, Virtual Reality Exposure Therapy, Ambulatory Blood Pressure Monitoring, Blood Pressure Disorders
Interventions
Virtual Reality Exposure
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 5, 2026, 9:01 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study

NCT06596265
View directory record Official record
Conditions
Anxiety, Wellness, Psychological, Overweight or Obesity, Hypertension, Prehypertension, Low Physical Fitness
Interventions
Fit2Lead Group 1-2
Behavioral
Lead sponsor
Duke University
Other
Eligibility
12 Years to 17 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Sep 5, 2026, 9:01 PM EDT
Enrolling by invitation Not applicable Interventional

To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years

NCT07387393
View directory record Official record
Conditions
Cardiometabolic Conditions, Hypertension (HTN), Dyslipidemia, Pre-diabetes, Type 2 Diabetes Mellitus (T2DM), Overweight (BMI > 25), Weight Loss Trial
Interventions
PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Fayetteville, Arkansas • Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of 7 Days of Grape Seed Extract Supplementation on Cold Pressor Test and Muscle Metaboreflex in Individuals With Elevated and Stage 1 Hypertension

NCT06428890
View directory record Official record
Conditions
Prehypertension
Interventions
Grape Seed Extract, Placebo
Dietary Supplement
Lead sponsor
California Baptist University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Riverside, California
Source: ClinicalTrials.gov public record
Updated May 23, 2024 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Not applicable Interventional

Mild Preeclampsia Near Term: Deliver or Deliberate?

NCT00789919
View directory record Official record
Conditions
Preeclampsia
Interventions
Delivery of infant
Procedure
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 9, 2017 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Not applicable Interventional

Hypotensive Effects of Conventional Dairy Products: Role of Arterial Stiffness

NCT01577030
View directory record Official record
Conditions
Prehypertension, Stage-1 Hypertension
Interventions
Non-fat dairy, Add 4 servings fruit
Dietary Supplement
Lead sponsor
University of Texas at Austin
Other
Eligibility
35 Years to 80 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2014 · Synced Sep 5, 2026, 9:01 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Aspirin (ASA) Therapy and Preeclampsia Prevention

NCT04158830
View directory record Official record
Conditions
Preeclampsia
Interventions
Aspirin 81 mg Enteric Coated Tab - 1 tablet, Aspirin 81 mg Enteric Coated Tab - 2 tablets
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
14 Years to 50 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Sep 5, 2026, 9:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Different Methods of Patient Education on Preeclampsia

NCT02765906
View directory record Official record
Conditions
Preeclampsia, Anxiety, Hypertension, Pregnancy, Eclampsia, HELLP
Interventions
Graphic card, Video
Other
Lead sponsor
Geisinger Clinic
Other
Eligibility
Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Danville, Pennsylvania • Forty Fort, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 15, 2020 · Synced Sep 5, 2026, 9:01 PM EDT
Active, not recruiting Not applicable Interventional

Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial

NCT05655936
View directory record Official record
Conditions
Preeclampsia, Hypertensive Disorder of Pregnancy, Toxemia, Pregnancy Complications, Hypertension, Pregnancy-Induced, Hypertension, Obesity, Overweight, Nutrition Disorders, Vascular Diseases, Cardiovascular Diseases, Pre-Eclampsia, Eclampsia, Gestational Hypertension
Interventions
Heart Health Doula Intervention Program, Usual Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
454 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 5, 2026, 9:01 PM EDT
Terminated Phase 4 Interventional

Metformin and Esomeprazole in Preterm Pre-eclampsia

NCT06359015
View directory record Official record
Conditions
Preeclampsia Severe, Pre-Eclampsia, Preeclampsia, Preeclampsia Second Trimester, Preeclampsia Complicating Childbirth, Preeclampsia Puerperium, Preterm
Interventions
Metformin, Esomeprazole
Drug
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Sep 5, 2026, 9:01 PM EDT