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ClinicalTrials.gov public records Last synced Oct 30, 2026, 8:41 PM EDT

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Showing 313–336 of 811 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: PreTerm Labor Clear all
Recruiting No phase listed Observational Accepts healthy volunteers

Prospective Evaluation of Pathways for Preterm Birth

NCT05246579
View directory record Official record
Conditions
Preterm Birth, Cervix; Pregnancy
Interventions
Not listed
Lead sponsor
John O'Brien, MD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Not applicable Interventional

Preterm Induction of Labor Timing of Amniotomy: A Randomized Controlled Trial

NCT03504670
View directory record Official record
Conditions
Preterm Pregnancy, Labor Induction
Interventions
Early Amniotomy, Late Amniotomy
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Oct 30, 2026, 8:41 PM EDT
Recruiting Phase 4 Interventional

Impact of Higher Zinc Supplementation on Neonatal Weight Velocity

NCT07896070
View directory record Official record
Conditions
Extreme Prematurity,Extremely Low Birthweight, BPD - Bronchopulmonary Dysplasia, Growth
Interventions
1 mg/day Zinc Supplementation, 3 mg/day Zinc Supplementation
Drug
Lead sponsor
Augusta University
Other
Eligibility
25 Weeks to 34 Weeks
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 26, 2026 · Synced Oct 30, 2026, 8:41 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Study to Support Fetal Heart Rate and Uterine Contraction for Preterm Labor in Singleton and Multiple Pregnancies

NCT01360905
View directory record Official record
Conditions
Pre Term Labor, Multiple Pregnancy
Interventions
Not listed
Lead sponsor
Monica Healthcare Ltd
Industry
Eligibility
17 Years and older · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 20, 2014 · Synced Oct 30, 2026, 8:41 PM EDT
Not yet recruiting Not applicable Interventional

Eye Tracking and Autism in Former Preterm Infants

NCT07764822
View directory record Official record
Conditions
Autism, Prematurity
Interventions
Eye-tracking device
Device
Lead sponsor
Indiana University
Other
Eligibility
14 Months to 48 Months
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 30, 2026, 8:41 PM EDT
Completed No phase listed Observational Results available

Comparative Effectiveness of Treatment Options for Genital Herpes Infection to Reduce Adverse Pregnancy Outcomes

NCT02986802
View directory record Official record
Conditions
HSV-2 Infection, PreTerm Birth, Pregnancy Complications
Interventions
Not listed
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older · Female only
Enrollment
89,132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2021 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Phase 2 Interventional Results available

Trial II of Lung Protection With Azithromycin in the Preterm Infant

NCT00319956
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Azithromycin, Placebo
Drug
Lead sponsor
Hubert Ballard
Other
Eligibility
Up to 72 Hours
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2012
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 27, 2018 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Vaginal Versus Intramuscular Progesterone for the Prevention of Recurrent Preterm Birth

NCT02913495
View directory record Official record
Conditions
Premature Birth
Interventions
Vaginal Progesterone, Intramuscular Progesterone (17 alpha hydroxprogesterone caproate)
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older · Female only
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Springfield, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 30, 2026, 8:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers Results available

Nurse-Family Partnership Impact Evaluation in South Carolina

NCT03360539
View directory record Official record
Conditions
Preterm Birth, Injuries, Maternal Behavior
Interventions
Nurse-Family Partnership
Behavioral
Lead sponsor
Harvard School of Public Health (HSPH)
Other
Eligibility
15 Years to 55 Years · Female only
Enrollment
5,670 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2046
U.S. locations
9
States / cities
Anderson, South Carolina • Charleston, South Carolina • Columbia, South Carolina + 6 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Not applicable Interventional Results available

Study of Nasal Ventilation In Preterm Infants To Decrease Time on The Respirator

NCT01440647
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Extubation to NIPPV, Extubation to CPAP
Procedure
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
Up to 48 Hours
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 12, 2013 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Not applicable Interventional

Early Progressive Feeding in Human-Milk Fed Extremely Preterm Infants: A Randomized Trial

NCT02915549
View directory record Official record
Conditions
Premature; Infant, Light-for-dates
Interventions
Progressive Feeding without MEF, Progressive Feeding with MEF
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
24 Hours to 48 Hours
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 16, 2022 · Synced Oct 30, 2026, 8:41 PM EDT
Terminated Phase 4 Interventional

Safety/Efficacy Study of Optimizing Ibuprofen Dosing to Achieve Higher PDA Closure Rates

NCT00961753
View directory record Official record
Conditions
Patent Ductus Arteriosus
Interventions
optimized ibuprofen, Standard Ibuprofen
Drug
Lead sponsor
OSF Healthcare System
Other
Eligibility
1 Day to 29 Days
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 28, 2014 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Phase 2 Interventional Results available

Improving Right Ventricular Function in Young Adults Born Preterm

NCT03696758
View directory record Official record
Conditions
Infant,Premature
Interventions
Pulmonary Function Testing, Electrocardiogram, Cardiac Magnetic Resonance Imaging, Metoprolol, Sildenafil
Procedure · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Not applicable Interventional Results available

Prevention of Preterm Birth With a Pessary in Twin Gestations

NCT02056639
View directory record Official record
Conditions
Premature Birth, Short Cervix
Interventions
Bioteque cup pessary
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
3
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 29, 2018 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Presenting Survival Information as Text or Pictograph During Periviable Birth Counseling

NCT04859114
View directory record Official record
Conditions
Premature Birth
Interventions
Format of outcome data presentation, Displayed chance of survival
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
1,052 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 24, 2023 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Health and Wellness After Preterm Birth

NCT05756634
View directory record Official record
Conditions
Preterm Birth, Health Care Utilization, Tobacco Use, Contraceptive Usage, Depression, Weight, Birth
Interventions
Care Coordination after Preterm Birth (CCAPB)
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Oct 30, 2026, 8:41 PM EDT
Terminated Not applicable Interventional Results available

Foley Catheter for Labor Induction in Women With Term and Near Term Membrane Rupture

NCT00290199
View directory record Official record
Conditions
Fetal Membranes, Premature Rupture, Labor, Induced/IS
Interventions
Transcervical Foley catheter
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
12 Years to 55 Years · Female only
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
3
States / cities
Birmingham, Alabama • Newark, Delaware • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated May 23, 2017 · Synced Oct 30, 2026, 8:41 PM EDT
Completed No phase listed Observational

Work of Breathing and Kangaroo Mother Care

NCT03683316
View directory record Official record
Conditions
Premature Infant, Work of Breathing, Oxygen Saturation
Interventions
Not listed
Lead sponsor
Christiana Care Health Services
Other
Eligibility
4 Days to 6 Months
Enrollment
29 participants
Timeline
2018 – 2020
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Phase 2Phase 3 Interventional

Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity

NCT01203436
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Retinopathy of Prematurity, Blindness
Interventions
Supplemental Oxygen Management, Conventional Oxygen Management
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 48 Hours
Enrollment
649 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 1999
U.S. locations
9
States / cities
Palo Alto, California • New Haven, Connecticut • Atlanta, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2015 · Synced Oct 30, 2026, 8:41 PM EDT
Completed Phase 2 Interventional Results available

Randomized Study of Weekly Erythropoietin Dosing in Preterm Infants

NCT01235923
View directory record Official record
Conditions
Preterm Infants
Interventions
three times weekly Epo, weekly Epo
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
7 Days to 100 Days
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Oct 30, 2026, 8:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Maternal Gut Microbiome (MGM) Study of Diet, the Gut Microbiome and Preterm Birth

NCT02560246
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Oct 30, 2026, 8:41 PM EDT
Active, not recruiting No phase listed Observational

Post-Discharge Growth of Infants Who Received Donor Human Milk Products in the Neonatal Intensive Care Unit (NICU)

NCT01483079
View directory record Official record
Conditions
Prematurity
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Not listed
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 30, 2026, 8:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessment of Lung Structure and Function of Infants Born Prematurely

NCT00422305
View directory record Official record
Conditions
Premature Birth, Bronchopulmonary Dysplasia, Asthma
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
2 Months to 36 Months
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Oct 30, 2026, 8:41 PM EDT
Active, not recruiting Phase 2 Interventional Results available

Bilirubin Neurotoxicity (BN) and Neurodevelopmental Impairment (NDI) in Extremely Preterm (EP) Infants: Avoidable by Reducing the Usual Intravenous Lipid (UL) Administration

NCT04584983
View directory record Official record
Conditions
Bilirubin Encephalopathy
Interventions
usual prescribed intralipid (UL) regimen, restricted prescribed intralipid (RL) regimen
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Up to 27 Weeks
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 28, 2025 · Synced Oct 30, 2026, 8:41 PM EDT