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ClinicalTrials.gov public records Last synced Oct 14, 2026, 9:24 AM EDT

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Showing 145–168 of 222 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Preeclampsia and Eclampsia Clear all
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

MR and Inflammation After Preeclampsia

NCT07345845
View directory record Official record
Conditions
Preeclampsia, Preeclampsia Postpartum
Interventions
Eplerenone
Drug
Lead sponsor
Anna Stanhewicz, PhD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 14, 2026, 9:24 AM EDT
Recruiting Phase 4 Interventional

A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)

NCT06785116
View directory record Official record
Conditions
Gestational Hypertension, Hypertension in Pregnancy, Pre-Eclampsia, Superimposed Pre-Eclampsia, Cardiovascular Complication
Interventions
Placebo, Dapagliflozin 10mg Tab
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 14, 2026, 9:24 AM EDT
Completed Not applicable Interventional Results available

Neonatal Sleep Intervention to Improve Postpartum Hypertension

NCT04864249
View directory record Official record
Conditions
Pre-Eclampsia, Gestational Hypertension, Sleep
Interventions
SNOO, Safe sleep education in the postpartum period
Device · Other
Lead sponsor
Alisse Hauspurg
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Oct 14, 2026, 9:24 AM EDT
Completed Phase 1 Interventional

Pravastatin for Prevention of Preeclampsia

NCT01717586
View directory record Official record
Conditions
Preeclampsia
Interventions
Pravastatin, Placebo
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2024
U.S. locations
3
States / cities
Chicago, Illinois • Pittsburgh, Pennsylvania • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 14, 2026, 9:24 AM EDT
Completed Not applicable Interventional Results available

App-based Remote Blood Pressure Monitoring

NCT05595629
View directory record Official record
Conditions
Gestational Hypertension, Preeclampsia, Chronic Hypertension Complicating Pregnancy
Interventions
App-based remote blood pressure monitoring, text-message based remote blood pressure monitoring
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Oct 14, 2026, 9:24 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Mechanisms of Pregnancy Vascular Adaptations

NCT03806283
View directory record Official record
Conditions
Pre-Eclampsia, Vascular Diseases
Interventions
Omental Biopsy
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
166 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 14, 2026, 9:24 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Retrospective Review of the Seasonality of Pre-Eclampsia

NCT00826696
View directory record Official record
Conditions
Preeclampsia
Interventions
Not listed
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 28, 2010 · Synced Oct 14, 2026, 9:24 AM EDT
Active, not recruiting Phase 3 Interventional Accepts healthy volunteers

Natural Versus Programmed Frozen Embryo Transfer (NatPro)

NCT04551807
View directory record Official record
Conditions
Pregnancy Related, Pre-Eclampsia
Interventions
Modified natural cycle, Programmed cycle
Procedure
Lead sponsor
JHSPH Center for Clinical Trials
Other
Eligibility
18 Years to 41 Years · Female only
Enrollment
788 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
15
States / cities
San Francisco, California • Sunnyvale, California • Orange, Connecticut + 12 more
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 14, 2026, 9:24 AM EDT
Not yet recruiting Phase 4 Interventional

Optimizing Preeclampsia Postpartum With Point-of-care Ultrasound

NCT07167862
View directory record Official record
Conditions
Preeclampsia, Preeclampsia Postpartum, Preeclampsia Severe or Mild
Interventions
Butterfly iQ3 ultrasound system for determination of postpartum volume status, Oral furosemide, Intravenous furosemide
Diagnostic Test · Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 14, 2026, 9:24 AM EDT
Not yet recruiting Not applicable Interventional

Community Health Worker Support to Lower Blood Pressure After a Pregnancy With High Blood Pressure

NCT07778966
View directory record Official record
Conditions
Pregnancy-Associated Hypertension, Gestational Hypertension, Preeclampsia, Eclampsia, HELLP Syndrome, Postpartum Hypertension, Stage 2 Hypertension
Interventions
Alabama Womb to Heart Solution (AW2H) Community Health Worker (CHW) Program, Usual postpartum care with self-measured blood pressure education and home blood pressure monitor
Behavioral · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
16 Years to 56 Years · Female only
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 14, 2026, 9:24 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Role of ASpirin in Placental and Maternal Endothelial Cell Regulation IN Pre-eclampsia

NCT03893630
View directory record Official record
Conditions
Pre-Eclampsia
Interventions
Acetylsalicylic Acid 81 mg, Acetylsalicylic Acid 162 mg, Control
Drug · Other
Lead sponsor
John O'Brien, MD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 29, 2025 · Synced Oct 14, 2026, 9:24 AM EDT
Terminated Not applicable Interventional Results available

Oral Progesterone and Low Dose Aspirin in the Prevention of Preeclampsia

NCT00719537
View directory record Official record
Conditions
Preeclampsia
Interventions
Aspirin, Placebo Oral Tablet, Progesterone
Drug
Lead sponsor
John Uckele
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Oct 14, 2026, 9:24 AM EDT
Active, not recruiting No phase listed Observational

MIRACLE of LIFE Study

NCT06074601
View directory record Official record
Conditions
Preterm Labor, Preterm Birth, Preterm Birth Complication, Preterm Premature Rupture of Membrane, Preeclampsia, HELLP, Gestational Hypertension, Gestational Diabetes Mellitus in Pregnancy, Small for Gestational Age at Delivery, Intrauterine Growth Restriction
Interventions
Mirvie Predictive Test for Adverse Pregnancy Outcomes
Diagnostic Test
Lead sponsor
Mirvie
Industry
Eligibility
18 Years and older · Female only
Enrollment
10,000 participants
Timeline
2021 – 2025
U.S. locations
10
States / cities
San Diego, California • Orlando, Florida • New Orleans, Louisiana + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 27, 2024 · Synced Oct 14, 2026, 9:24 AM EDT
Recruiting Phase 2 Interventional

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

NCT06333652
View directory record Official record
Conditions
Preeclampsia
Interventions
Ravulizumab
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 14, 2026, 9:24 AM EDT
Completed Phase 3 Interventional Results available

Pharmacokinetics, Safety and Efficacy Study of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia

NCT02059135
View directory record Official record
Conditions
Preeclampsia
Interventions
Recombinant human antithrombin (ATryn), Normal Saline 0.9%
Biological · Other
Lead sponsor
rEVO Biologics
Industry
Eligibility
16 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
23
States / cities
Birmingham, Alabama • Mobile, Alabama • Little Rock, Arkansas + 19 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2017 · Synced Oct 14, 2026, 9:24 AM EDT
Recruiting Not applicable Interventional

Mobile Health Program for Post-Preeclampsia Hypertension

NCT07599579
View directory record Official record
Conditions
Hypertension (HTN), Preeclampsia, Hypertensive Disorders of Pregnancy (HDP)
Interventions
Coaching application, Home-based blood pressure monitoring, WebMD
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 14, 2026, 9:24 AM EDT
Completed Phase 4 Interventional Results available

The Effect of Ibuprofen on Post-partum Blood Pressure in Women With Hypertensive Disorders of Pregnancy

NCT02891174
View directory record Official record
Conditions
Hypertension, Pregnancy-Induced, Pre-eclampsia
Interventions
Ibuprofen, Acetaminophen
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 23, 2019 · Synced Oct 14, 2026, 9:24 AM EDT
Completed Not applicable Interventional

Abbreviated MgSO4 Therapy in Post-partum Preeclampsia

NCT00344058
View directory record Official record
Conditions
Pregnancy, Preeclampsia
Interventions
abbreviation of magnesium sulfate therapy (12 hours versus the traditional 24 hours after delivery)
Drug
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 14, 2026, 9:24 AM EDT
Completed No phase listed Observational

First Trimester Prediction of Preeclampsia and Fetal Growth Restriction

NCT02379494
View directory record Official record
Conditions
Preeclampsia, Fetal Growth Restriction
Interventions
Not listed
Lead sponsor
Fetal Medicine Foundation
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 22, 2017 · Synced Oct 14, 2026, 9:24 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Effects of High Altitude on AMPK Activation

NCT02391519
View directory record Official record
Conditions
Pregnancy, IUGR, Preeclampsia
Interventions
Collection of myometrial, cord blood, and placental tissue samples
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 14, 2026, 9:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fit After Baby: Increasing Postpartum Weight Loss in Women at Increased Risk for Cardiometabolic Disease

NCT03215173
View directory record Official record
Conditions
Cardiovascular Diseases, Diabetes, Gestational Diabetes, Preeclampsia, Gestational Hypertension, Small for Gestational Age at Delivery, Preterm Birth, Overweight and Obesity
Interventions
Fit After Baby, Text4Baby Control Group
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 8, 2021 · Synced Oct 14, 2026, 9:24 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Non-Invasive Preeclampsia Screening and Biobank

NCT06643741
View directory record Official record
Conditions
Preeclampsia (PE)
Interventions
Not listed
Lead sponsor
Sequenom, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
6,550 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
21
States / cities
Glendale, Arizona • Newark, Delaware • Miami, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 14, 2026, 9:24 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Gene Expression In Pregnancies Complicated by Preeclampsia

NCT00919360
View directory record Official record
Conditions
Preeclampsia
Interventions
collection of maternal blood specimen prior to delivery, collection of placental cord blood after delivery, collection of placental tissue, collection of strip of decidua from uterine lining from cesarean section deliveries
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older · Female only
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2015 · Synced Oct 14, 2026, 9:24 AM EDT
Not yet recruiting No phase listed Observational

Gestational Changes in Hemodynamics and Respiratory Mechanics in Association With Pre-Eclampsia

NCT07695909
View directory record Official record
Conditions
Pre-eclampsia, Pregnancy, Post Partum
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 14, 2026, 9:24 AM EDT