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ClinicalTrials.gov public records Last synced Oct 26, 2026, 2:02 PM EDT

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Showing 433–456 of 1,214 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Premature Births Clear all
Terminated No phase listed Observational

Transfusion-related Inflammatory Cytokine and Neutrophil Extracellular Trap Quantification in Neonates

NCT01735552
View directory record Official record
Conditions
Anemia of Prematurity, Necrotizing Enterocolitis
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Up to 12 Weeks
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
3
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 5, 2015 · Synced Oct 26, 2026, 2:02 PM EDT
Terminated Not applicable Interventional

Vaginal Pessary Versus Expectant Management for Placenta Previa

NCT01996345
View directory record Official record
Conditions
Placenta Previa
Interventions
Cervical Pessary Placement
Procedure
Lead sponsor
Pediatrix
Other
Eligibility
18 Years to 54 Years · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
10
States / cities
Mobile, Alabama • Long Beach, California • San Jose, California + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Oct 26, 2026, 2:02 PM EDT
Completed Phase 1Phase 2 Interventional

N-acetylcysteine in Intra-amniotic Infection/Inflammation

NCT00397735
View directory record Official record
Conditions
Labor, Premature, Preterm Premature Rupture of the Membranes, Infection, Inflammation, Chorioamnionitis
Interventions
amniocentesis, N-acetylcysteine or placebo
Procedure · Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
2
States / cities
New Haven, Connecticut • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Oct 26, 2026, 2:02 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

NCT04278404
View directory record Official record
Conditions
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Hemophilia, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
Interventions
The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:
Drug
Lead sponsor
Duke University
Other
Eligibility
0 Years to 20 Years
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
49
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Los Angeles, California + 40 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 26, 2026, 2:02 PM EDT
Completed Phase 2Phase 3 Interventional

Mid and Standard Frequency Ventilation in Infants With Respiratory Distress Syndrome

NCT03231735
View directory record Official record
Conditions
Ventilator-Induced Lung Injury, Respiratory Distress Syndrome, Bronchopulmonary Dysplasia, Preterm Infant
Interventions
Mid frequency ventilation, Standard frequency ventilation
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 3 Days
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
2
States / cities
Birmingham, Alabama • Mobile, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 26, 2026, 2:02 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Microbiome And Multi'Omics In Preterm Birth: The Bacteria And Birth Study

NCT02392650
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
16 Years to 64 Years
Enrollment
526 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Oct 26, 2026, 2:02 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Preeclampsia Registry

NCT06377878
View directory record Official record
Conditions
Preeclampsia, Eclampsia, HELLP Syndrome, Toxemia, Hypertensive Disorder of Pregnancy
Interventions
Not listed
Lead sponsor
Preeclampsia Foundation
Other
Eligibility
13 Years and older
Enrollment
20,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2040
U.S. locations
1
States / cities
Melbourne, Florida
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Oct 26, 2026, 2:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Betamethasone Dosing Interval - 12 or 24 Hours?

NCT00453141
View directory record Official record
Conditions
Preterm Delivery
Interventions
dosing of Betamethasone
Drug
Lead sponsor
The Cooper Health System
Other
Eligibility
16 Years to 45 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
2
States / cities
Camden, New Jersey • Pomona, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 10, 2009 · Synced Oct 26, 2026, 2:02 PM EDT
Completed Not applicable Interventional

Antenatal Betamethasone Compared to Dexamethasone - "BETACODE TRIAL"

NCT00418353
View directory record Official record
Conditions
Respiratory Distress Syndrome, Intraventricular Hemorrhage, Neonatal Mortality
Interventions
Betamethasone(Celestone soluspan) and Dexamethasone
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jan 4, 2007 · Synced Oct 26, 2026, 2:02 PM EDT
Recruiting No phase listed Observational

Predictive Value of Lung Ultrasound for Respiratory Decompensation in Late Preterm Neonates

NCT07216053
View directory record Official record
Conditions
Pre-Term, Respiratory Distress of Newborn, Premature
Interventions
Point of care lung ultrasound
Diagnostic Test
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
34 Weeks to 36 Weeks
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 26, 2026, 2:02 PM EDT
Completed No phase listed Observational

Microarray Expression Profiling to Identify Stereotypic mRNA Profiles in Human Parturition

NCT00342277
View directory record Official record
Conditions
Preterm Birth, Premature Rupture of Membranes
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
Not listed
Enrollment
6,838 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2016
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 24, 2023 · Synced Oct 26, 2026, 2:02 PM EDT
Active, not recruiting No phase listed Observational

Local Version of the Multi-center PREVENT Study Evaluating Cardio-respiratory Instability in Premature Infants

NCT03655639
View directory record Official record
Conditions
Premature Birth
Interventions
Not listed
Lead sponsor
Aaron Hamvas
Other
Eligibility
24 Weeks to 29 Weeks
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 26, 2026, 2:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pain and Stress Assessment and ROP Screening

NCT02415205
View directory record Official record
Conditions
Pain, Stress
Interventions
Not listed
Lead sponsor
Loma Linda University
Other
Eligibility
24 Weeks to 32 Weeks
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2018 · Synced Oct 26, 2026, 2:02 PM EDT
Not yet recruiting Not applicable Interventional

ADINA vs. High Flow Nasal Cannula Comparison Study

NCT03171129
View directory record Official record
Conditions
Respiratory Distress Neonatal
Interventions
Adaptive Dynamic Inspiratory Nasal Apparatus, High flow Nasal Canula
Device
Lead sponsor
Loma Linda University
Other
Eligibility
23 Weeks to 40 Weeks
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 26, 2026, 2:02 PM EDT
Completed Phase 3 Interventional

Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants

NCT00006401
View directory record Official record
Conditions
Lung Diseases, Bronchopulmonary Dysplasia
Interventions
iNO, Placebo
Drug · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Up to 1 Year
Enrollment
793 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2007
U.S. locations
14
States / cities
Phoenix, Arizona • Loma Linda, California • Los Angeles, California + 11 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2015 · Synced Oct 26, 2026, 2:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Immunogenicity of PCV-7 Vaccine in VLBW Infants

NCT00273325
View directory record Official record
Conditions
Pneumococcal Infections, Streptococcus Pneumoniae, Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 3 Months
Enrollment
368 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
10
States / cities
Birmingham, Alabama • Palo Alto, California • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2019 · Synced Oct 26, 2026, 2:02 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Indomethacin Germinal Matrix Hemorrhage/Intraventricular Hemorrhage (GMH/IVH) Prevention Trial

NCT00033917
View directory record Official record
Conditions
Intraventricular Hemorrhage (IVH), Bleeding in the Brain, Prematurity, Very Low Birth Weight Infants
Interventions
indomethacin, placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
Up to 6 Hours
Enrollment
630 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1989 – 2012
U.S. locations
3
States / cities
New Haven, Connecticut • Portland, Maine • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 28, 2013 · Synced Oct 26, 2026, 2:02 PM EDT
Completed Phase 1Phase 2 Interventional

Effects of Massage on the Immune System of Preterm Infants

NCT00317278
View directory record Official record
Conditions
Premature Birth, Stress
Interventions
massage therapy, Sham
Other
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
28 Weeks to 33 Weeks
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 7, 2009 · Synced Oct 26, 2026, 2:02 PM EDT
Completed No phase listed Observational

Establishment of a Perinatal Database and a Bank of Biological Materials

NCT00339235
View directory record Official record
Conditions
Preterm Labor, Preterm Birth, Pregnancy
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older · Female only
Enrollment
30,570 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2016
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 24, 2023 · Synced Oct 26, 2026, 2:02 PM EDT
Terminated Phase 2 Interventional Results available

Randomized Controlled Trial to Evaluate the Safety and Efficacy of Acetaminophen in Preterm Infants Used in Combination With Ibuprofen for Closure of the Ductus Arteriosus

NCT03701074
View directory record Official record
Conditions
Patent Ductus Arteriosus, Preterm Infant, Bronchopulmonary Dysplasia
Interventions
Ibuprofen and acetaminophen, Ibuprofen and placebo
Drug
Lead sponsor
University of South Alabama
Other
Eligibility
5 Days to 21 Days
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Mobile, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 26, 2026, 2:02 PM EDT
Completed Phase 3 Interventional

The Effects of Light Reduction on Retinopathy of Prematurity (Light-ROP)

NCT00000156
View directory record Official record
Conditions
Retinopathy of Prematurity
Interventions
Goggles, Ambient Light Reduction
Device · Procedure
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
Up to 1 Day
Timeline
Started 1995
U.S. locations
3
States / cities
Buffalo, New York • Dallas, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 5, 2006 · Synced Oct 26, 2026, 2:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Do Elevated BNP Levels Predict Hemodynamically Significant PDAs

NCT01497054
View directory record Official record
Conditions
Patent Ductus Arteriosus
Interventions
Not listed
Lead sponsor
Albany Medical College
Other
Eligibility
1 Hour to 24 Hours
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Jul 4, 2013 · Synced Oct 26, 2026, 2:02 PM EDT
Completed Phase 1 Interventional

Effects of Delayed Cord Clamping in Very Low Birth Weight Infants

NCT00840983
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Necrotizing Enterocolitis, Intraventricular Hemorrhage, Late Onset Neonatal Sepsis, Motor Skills Disorders
Interventions
delayed cord clamping
Procedure
Lead sponsor
University of Rhode Island
Other
Eligibility
Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 30, 2015 · Synced Oct 26, 2026, 2:02 PM EDT
Completed Not applicable Interventional

Liquid Preterm Formula Versus Powdered Human Milk Fortifier in VLBW Infants

NCT00760942
View directory record Official record
Conditions
Infant, Very Low Birth Weight
Interventions
Similac special care 30, Similac human milk fortifier
Dietary Supplement
Lead sponsor
University of Oklahoma
Other
Eligibility
1 Day to 10 Weeks
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 10, 2013 · Synced Oct 26, 2026, 2:02 PM EDT