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ClinicalTrials.gov public records Last synced Oct 30, 2026, 2:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 745–768 of 1,214 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Premature Births Clear all
Completed Phase 1 Interventional

Pharmacokinetics of Sildenafil in Premature Infants

NCT01670136
View directory record Official record
Conditions
Persistent Pulmonary Hypertension of the Newborn
Interventions
1 dose of sildenafil
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
Up to 364 Days
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
9
States / cities
Birmingham, Alabama • Indianapolis, Indiana • Louisville, Kentucky + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2016 · Synced Oct 30, 2026, 2:47 AM EDT
Recruiting Not applicable Interventional

Randomized Controlled Crossover Trial of Postpyloric Feedings to Improve Pulmonary Outcomes in High-risk Preterm Infants

NCT05777512
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Gastric Feeds, Jejunal Feeds
Procedure
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Hours to 1 Year
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 30, 2026, 2:47 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Indomethacin Versus Placebo in Women With Preterm Premature Rupture of Membranes (PPROM)

NCT00466128
View directory record Official record
Conditions
Preterm Premature Rupture of Membranes
Interventions
indomethacin
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
15 Years to 50 Years · Female only
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 18, 2015 · Synced Oct 30, 2026, 2:47 AM EDT
Recruiting Not applicable Interventional

Optimization of Saturation Targets And Resuscitation Trial (OptiSTART)

NCT05849077
View directory record Official record
Conditions
Premature Infants, Bronchopulmonary Dysplasia, Intraventricular Hemorrhage, Neurodevelopmental Outcomes
Interventions
Sat75, Sat50
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
0 Minutes to 10 Minutes
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Oct 30, 2026, 2:47 AM EDT
Completed Not applicable Interventional

Effects of Milking the Umbilical Cord on Systemic Blood Flow

NCT01434732
View directory record Official record
Conditions
Abnormal Vascular Flow
Interventions
Umbilical Cord Milking, Immediate Cord Clamping
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2017 · Synced Oct 30, 2026, 2:47 AM EDT
Completed Phase 3 Interventional

Dose Comparison of Amino Acids on Growth in Premature Neonates

NCT00120926
View directory record Official record
Conditions
Malnutrition
Interventions
Parenteral Nutrition
Drug
Lead sponsor
Pediatrix
Other
Eligibility
0 Years to 48 Hours
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Florence, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 28, 2006 · Synced Oct 30, 2026, 2:47 AM EDT
Completed Not applicable Interventional Results available

Comparison of Transdermal and Oral Estrogens in Adolescent Girls With Ovarian Failure

NCT01023178
View directory record Official record
Conditions
Ovarian Failure, Premature
Interventions
17beta Estradiol, Conjugated estrogens, 17Beta Estradiol - transdermal, Progesterone, micronized
Drug
Lead sponsor
Stanford University
Other
Eligibility
12 Years to 18 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2017 · Synced Oct 30, 2026, 2:47 AM EDT
Completed Not applicable Interventional

A Study to Evaluate the Safety and Tolerability of Zidovudine (ZDV) in Premature Infants Born to HIV-Positive Women.

NCT00000855
View directory record Official record
Conditions
HIV Infections
Interventions
Zidovudine
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
1 Day to 5 Days
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2000
U.S. locations
35
States / cities
Birmingham, Alabama • Phoenix, Arizona • La Jolla, California + 25 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Oct 30, 2026, 2:47 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Immunogenicity of PCV-7 Vaccine in VLBW Infants

NCT00273325
View directory record Official record
Conditions
Pneumococcal Infections, Streptococcus Pneumoniae, Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 3 Months
Enrollment
368 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
10
States / cities
Birmingham, Alabama • Palo Alto, California • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2019 · Synced Oct 30, 2026, 2:47 AM EDT
Terminated Phase 2 Interventional Results available

Premature Ventricular Contractions (PVCs) and Blood Pressure Control

NCT01833455
View directory record Official record
Conditions
Ventricular Premature Complexes, Blood Pressure
Interventions
PVC Suppression using Flecainide, No PVC Suppression using Placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 22, 2019 · Synced Oct 30, 2026, 2:47 AM EDT
Completed Early Phase 1 Interventional

ETCare: Safety and Preliminary Efficacy Trial

NCT01688440
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
#1 Respiratory Care Solution
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
2
States / cities
Ogden, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 19, 2012 · Synced Oct 30, 2026, 2:47 AM EDT
Completed Not applicable Interventional

Trial of a Limited Versus Traditional Oxygen Strategy During Resuscitation in Premature Newborns

NCT01697904
View directory record Official record
Conditions
Prematurity, Oxidative Stress
Interventions
Titration of oxygen during newborn resuscitation in delivery room
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 2, 2012 · Synced Oct 30, 2026, 2:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)

NCT03906435
View directory record Official record
Conditions
Premature Infant, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Development, Child, Parent-Child Relations
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 30, 2026, 2:47 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Randomized Trial Comparing Misoprostol and Foley Bulb for Labor Induction in the Preterm Gestation

NCT00325026
View directory record Official record
Conditions
Premature Birth, Cervical Ripening
Interventions
Misoprostol, Foley bulb
Drug · Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 2, 2012 · Synced Oct 30, 2026, 2:47 AM EDT
Terminated Not applicable Interventional Results available

High Flow Nasal Cannula Versus Bubble Nasal CPAP for the Treatment of Transient Tachypnea of the Newborn in Infants ≥ 35 Weeks Gestation

NCT01270581
View directory record Official record
Conditions
Transient Tachypnea of the Newborn
Interventions
High Flow Nasal Cannula, Bubble Nasal CPAP
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
Up to 24 Hours
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 16, 2017 · Synced Oct 30, 2026, 2:47 AM EDT
Completed Not applicable Interventional

Clinical Use Cases Assessment of the Gabi System in Young Children With Underlying Medical Conditions (BRIDGE Study)

NCT05319236
View directory record Official record
Conditions
Cardiac Disease, Respiratory Disease, Congenital Cardiac Defect, Cardiovascular Diseases, Chronic Respiratory Disease, Chronic Cardiopulmonary Disease, Premature Infant Disease
Interventions
Gabi System
Device
Lead sponsor
Gabi SmartCare
Industry
Eligibility
Up to 5 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Washington D.C., District of Columbia • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Oct 30, 2026, 2:47 AM EDT
Not yet recruiting Not applicable Interventional

Human Milk Concentrating Device to Optimize Mother's Own Milk

NCT07576972
View directory record Official record
Conditions
Preterm Infant Health, Premature Babies
Interventions
Human Milk Concentration Device, Standard of Care Fortified Feeding
Device · Other
Lead sponsor
Mother's Milk is Best
Industry
Eligibility
32 Weeks to 35 Weeks
Enrollment
310 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 30, 2026, 2:47 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers Results available

The Safety and Efficacy Study of RiaGev in Healthy Adults

NCT04483011
View directory record Official record
Conditions
Metabolic Syndrome, Premature Aging
Interventions
RiaGev
Dietary Supplement
Lead sponsor
Bioenergy Life Science, Inc.
Industry
Eligibility
36 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 25, 2020 · Synced Oct 30, 2026, 2:47 AM EDT
Completed No phase listed Observational

Impact of Respiratory Pathogens in Infants

NCT01789268
View directory record Official record
Conditions
Respiratory Tract Infection
Interventions
Respiratory Inductive Plethysmography
Device
Lead sponsor
University of Rochester
Other
Eligibility
0 Days to 3 Years
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Oct 30, 2026, 2:47 AM EDT
Completed Not applicable Interventional

Parent Training for Parents of Toddlers Born Very Premature:

NCT05217615
View directory record Official record
Conditions
Parenting, Problem Behavior, Premature Birth, Parenting Intervention
Interventions
ezParent, Coaching calls, Active Control
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
20 Months and older
Enrollment
452 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
3
States / cities
Chicago, Illinois • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 30, 2026, 2:47 AM EDT
Completed Phase 1 Interventional Results available

Intestinal Permeability in Preterm Infants

NCT01756040
View directory record Official record
Conditions
Prematurity, Intestinal Permeability
Interventions
Lactulose -rhamnose solution
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
Up to 4 Days
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 30, 2026, 2:47 AM EDT
Recruiting Not applicable Interventional

Targeted Fortification of Donor Breast Milk in Preterm Infants

NCT04294368
View directory record Official record
Conditions
Prematurity; Extreme, Failure to Thrive in Newborn, Growth Retardation, Growth Failure, Infant Nutrition Disorders
Interventions
Similac Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid, Similac Liquid Protein Fortifier, Nestle Microlipid, Medica Nutrition SolCarb, Similac Human Milk Fortifier Extensively Hydrolyzed Protein Concentrated Liquid (Targeted Fortification), Similac Liquid Protein Fortifier (Targeted Fortification), Nestle Microlipid (Targeted Fortification), Medica Nutrition SolCarb (Targeted Fortification), Analysis with Miris (AB) Human Milk Analyzer
Dietary Supplement · Other
Lead sponsor
Columbia University
Other
Eligibility
1 Day to 21 Days
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 30, 2026, 2:47 AM EDT
Withdrawn Not applicable Interventional

Oscillatory Versus Non-Oscillatory Nasal Continuous Airway Pressure Neonatal Respiratory Support

NCT01277874
View directory record Official record
Conditions
Respiratory Distress Syndrome, Prematurity
Interventions
Nasal CPAP, Oscillatory NCPAP
Device
Lead sponsor
University of Utah
Other
Eligibility
Up to 28 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
Madera, California • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 30, 2026, 2:47 AM EDT
Completed Not applicable Interventional

Fluid Restriction in Respiratory Distress of the Newborn

NCT03120585
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
Fluid Management Intervention
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
Up to 12 Hours
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
2
States / cities
New York, New York • Lawton, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Oct 30, 2026, 2:47 AM EDT