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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:12 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 169–192 of 748 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Preterm Labor, Premature Birth Clear all

Conditions: Premature Birth of Newborn, Family, Immature Newborn, Newborn Morbidity, Infant Newborn Disease
Interventions: Parent Navigator, Care Notebook; Behavioral
Lead sponsor: Children's National Research Institute; Other
Eligibility: Not listed
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Apnea of Prematurity
Interventions: Stochastic Resonance Mattress; Device
Lead sponsor: Wyss Institute at Harvard University; Other
Eligibility: Not listed
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Postpartum Depression, Preterm Infant, Infant Development
Interventions: Newborn Behavioral Observation-Family Wellness (NBO-FW); Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Bronchopulmonary Dysplasia, Encephalomalacia, Premature Birth
Interventions: Hydrocortisone, Placebo; Drug
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 1 Week to 3 Weeks
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2012
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Respiratory Distress Syndrome (Neonatal), Intubation Complication, Death; Neonatal
Interventions: Infasurf Aero™; Combination Product
Lead sponsor: ONY; Industry
Eligibility: 29 Weeks to 36 Weeks
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 10
States / cities: Phoenix, Arizona • San Diego, California • Jacksonville, Florida + 6 more

Conditions: Respiratory Distress Syndrome
Interventions: Gradual pressure wean; Other
Lead sponsor: Maimonides Medical Center; Other
Eligibility: 26 Weeks to 32 Weeks
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Preterm Birth Complication, Preterm Birth, Preterm Birth Recurrence, Preeclampsia, Preeclampsia (PE), Hypertensive Disorders of Pregnancy, Support Program, Stress, Resilience, Psychological, Empowerment, Patient, Emotional Stress, Pregnancy, Pregnancy Complications, Pregnancy Induced Hypertension, Neonates and Preterm Infants, Cervical Insufficiency, Social Determinants of Health (SDOH), Cervical Shortening, Disparities in Pregnancy Complications, Disparities, Prenatal Care, Care Coordination
Interventions: Care coordination, Electronic massage, support gift #1, Support gift #2, Support gift #3, Support gift #4, Additional PTBCARE+ support, Stress reduction toolkit - Visit 1 (V1), PTBCARE+ mobile application (app) and website, Sleep, meditation, and Wellness app, Emergency low blood sugar kit, Low dose aspirin (LDA), Visit #2 Stress Reduction Toolkit; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1,228 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Bronchopulmonary Dysplasia, Prematurity
Interventions: Protocolized weaning of respiratory support; Other
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 22 Weeks to 30 Weeks
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Prematurity, Apnea, Respiratory Failure
Interventions: Caffeine citrate, Normal saline; Drug · Other
Lead sponsor: University of Miami; Other
Eligibility: 1 Day to 5 Days
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Preterm Birth, Health Care Utilization, Tobacco Use, Contraceptive Usage, Depression, Weight, Birth
Interventions: Care coordination and motivational interviewing; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 14 Years to 45 Years · Female only
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Preterm Birth, Child Development, Child Behavior
Interventions: LCPUFA oil supplement, Canola Oil Placebo; Drug · Other
Lead sponsor: Sarah Keim; Other
Eligibility: 18 Months to 39 Months
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Intracranial Hemorrhage, Intraventricular Hemorrhage, Cerebral Hypoxia
Interventions: No intervention/treatment is given; Other
Lead sponsor: Nelson Claure; Other
Eligibility: 1 Day to 28 Days
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2023
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Respiratory Insufficiency of Prematurity
Interventions: nCPAP, NIPPV; Device
Lead sponsor: McMaster University; Other
Eligibility: Up to 28 Days
Enrollment: 1,011 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 14
States / cities: Washington D.C., District of Columbia • Boston, Massachusetts • Voorhees Township, New Jersey + 6 more

Conditions: Length of Pregnancy Prolongation in Hours
Interventions: erythromycin and metronidazole (antibiotics), placebo; Drug
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Premature Newborn, Necrotizing Enterocolitis
Interventions: Citrulline samples; Diagnostic Test
Lead sponsor: University of Miami; Other
Eligibility: Not listed
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2017
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Placenta Previa
Interventions: Cervical Pessary Placement; Procedure
Lead sponsor: Pediatrix; Other
Eligibility: 18 Years to 54 Years · Female only
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 10
States / cities: Mobile, Alabama • Long Beach, California • San Jose, California + 6 more

Conditions: Pregnancy Preterm, Pregnancy Prom, PROM, Preterm (Pregnancy), PROM (Pregnancy), Premat Rupture Membranes Preterm Unspec to Length of Time Between Rupture/Labor, Premature Birth
Interventions: Azithromycin Pill, Amoxicillin Pill; Drug
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1 participant
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 3
States / cities: Cleveland, Ohio

Conditions: Premature Infants
Interventions: Liquid human milk fortifier, Powder human milk fortifier; Other
Lead sponsor: Mead Johnson Nutrition; Industry
Eligibility: Up to 40 Days
Enrollment: 143 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 14
States / cities: Little Rock, Arkansas • Jacksonville, Florida • Plantation, Florida + 10 more

Conditions: Premature Birth
Interventions: massage, Sham massage; Procedure
Lead sponsor: University of Miami; Other
Eligibility: 28 Weeks to 32 Weeks
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Preterm Birth, Nutrition, Healthy
Interventions: Preterm Infant Formula; Dietary Supplement
Lead sponsor: Augusta University; Other
Eligibility: 28 Days and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Fluid Loss, Dehydration, Extreme Immaturity
Interventions: Sterile water application; Other
Lead sponsor: George Washington University; Other
Eligibility: Up to 24 Hours
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Prematurity, BPD - Bronchopulmonary Dysplasia, Respiratory Distress Syndrome, Newborn
Interventions: Volume Targeted Ventilation (VTV) using the Philips Respironics NM3 monitor, Tidal Volume Measurement using the Philips Respironics NM3 monitor; Device
Lead sponsor: Baystate Medical Center; Other
Eligibility: 5 Minutes to 60 Minutes
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Springfield, Massachusetts

Conditions: Preterm Birth
Interventions: Not listed
Lead sponsor: University of Pennsylvania; Other
Eligibility: 13 Years to 50 Years · Female only
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Infant, Premature
Interventions: Not listed
Lead sponsor: University of Virginia; Other
Eligibility: Up to 1 Week
Enrollment: 739 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Charlottesville, Virginia

Search by objective public record fields.

GPS (Giving Parents Support): Parent Navigation After NICU Discharge

Stochastic Resonance Mattress (Physiological Interventions) and Biomarkers for Enhancing Neonatal Health

The Impact of a Newborn Behavioral Intervention on the Mental Health of Mothers With Late Pre-Term Infants

Randomized Trial of Hydrocortisone in Very Preterm High-Risk Infants

InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS

Comparing Weaning of Nasal Continuous Positive Airway Pressure (CPAP) From Preterm Infants

Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities

Impact of Extended CPAP on Bronchopulmonary Dysplasia

Caffeine to Reduce Mechanical Ventilation in Preterm Infants

Testing Feasibility of Care Coordination and Motivational Interviewing for Women With a Recent Preterm Birth

Preemie Tots: A Pilot Study to Understand the Effects of Prematurity in Toddlerhood

Observational Study in Preterm Infants With Intracranial Hemorrhage

Nasal Intermittent Positive Pressure Ventilation in Premature Infants (NIPPV)

Antibiotics and the Prolongation of Pregnancy in Preterm Labor With an Advanced Cervical Exam

Defining Normal Citrulline Levels as a Diagnostic Tool for Screening of Gastrointestinal Disease in Premature Infants

Vaginal Pessary Versus Expectant Management for Placenta Previa

Outpatient Antibiotics Following Previable Rupture of Membranes (pPPROM) Between 18 0/7 and 22 6/7 Weeks Gestational Age

Feeding Study in Premature Infants

Preterm Infants' Weight Gain Following Massage Therapy

Transition From Donor Milk: a Feasibility Study

The Application of Sterile Water to the Skin of Extremely Low Birth Weight (ELBW) Infants

Feasibility and Impact of Volume Targeted Ventilation in the Delivery Room

Motherhood and Microbiome

Prematurity-Related Ventilatory Control: Role in Respiratory Outcomes