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Showing 1–24 of 89 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Fetal Membranes, Premature Rupture
Interventions
Retention of Cerclage, Removal of Cerclage, Removal vs. Retention of Cervical Cerclage
Procedure
Lead sponsor
Obstetrix Medical Group
Industry
Eligibility
18 Years to 60 Years · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2014
U.S. locations
23
States / cities
Mesa, Arizona • Phoenix, Arizona • Tucson, Arizona + 18 more
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Respiratory Distress Syndrome (RDS), Sepsis, Pneumonia, Hypertension, Pulmonary
Interventions
Inhaled nitric oxide, Placebo
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 120 Hours
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
17
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 14 more
Recruiting Phase 2 Interventional Accepts healthy volunteers

The Effect of Sulfasalazine on CRH Levels in Pregnant Women

NCT05703425
Conditions
Preterm Birth
Interventions
Sulfasalazine
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
New Brunswick, New Jersey
Conditions
Preeclampsia Severe, Pre-Eclampsia, Preeclampsia, Preeclampsia Second Trimester, Preeclampsia Complicating Childbirth, Preeclampsia Puerperium, Preterm
Interventions
Metformin, Esomeprazole
Drug
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Conditions
Premature Birth of Newborn
Interventions
Family Integrated Care
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
Up to 33 Weeks
Enrollment
347 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
6
States / cities
Fresno, California • La Jolla, California • Oakland, California + 3 more
Conditions
Intra-amniotic Infection
Interventions
Not listed
Lead sponsor
ProteoGenix, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
21
States / cities
Mesa, Arizona • Phoenix, Arizona • Tucson, Arizona + 16 more
Conditions
Preterm Labor, Preterm Birth
Interventions
Not listed
Lead sponsor
Ranjith Kamity, MD
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Mineola, New York
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
KC BioMediX, Inc
Industry
Eligibility
34 Weeks to 18 Months
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Raleigh, North Carolina
Completed Phase 3 Interventional Results available

Oral Progesterone for Prevention of Preterm Birth

NCT01180296
Conditions
Preterm Birth
Interventions
oral micronized progesterone, Identical Placebo tablet
Drug
Lead sponsor
Fetal Medicine Foundation
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Dayton, Ohio
Conditions
Diabetes Mellitus, Type 2, Preterm Birth, Pregnancy, High Risk, Diabetes, Gestational
Interventions
Sliding Scale Insulin, Up-Titration of Home Insulin, Continuous Insulin Infusion, Dexcom G6 Professional Continuous Glucose Monitor
Drug · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
Up to 50 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Birmingham, Alabama • Portland, Oregon • Greenville, South Carolina + 1 more
Conditions
Preterm Birth
Interventions
Hydroxyprogesterone Caproate Injection (HPC), 250mg/mL, Vehicle
Drug
Lead sponsor
AMAG Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,740 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
41
States / cities
Montgomery, Alabama • Tucson, Arizona • La Mesa, California + 35 more
Conditions
Preterm Delivery
Interventions
Not listed
Lead sponsor
Hologic, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
329 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
5
States / cities
San Jose, California • New Haven, Connecticut • Atlanta, Georgia + 2 more
Conditions
Preterm Birth
Interventions
Participant Barriers to TVU Screening, Provider Barriers to TVU Screening
Behavioral
Lead sponsor
Niraj Chavan
Other
Eligibility
18 Years to 49 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Not yet recruiting Not applicable Interventional

Music Intervention for Preterm Birth

NCT05945264
Conditions
Preterm Birth
Interventions
Music Intervention (MI), Sham Control (SC)
Behavioral · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
New York, New York
Conditions
Bronchopulmonary Dysplasia, Prematurity
Interventions
Care coordination by telephone contacts with a nurse
Procedure
Lead sponsor
Wake Forest University
Other
Eligibility
1 Day to 483 Days
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2000
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Preterm Labor With Preterm Delivery, Premature Birth, Apnea of Prematurity, Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
Interventions
Caffeine citrate
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Infant Malnutrition, Light-For-Dates With Signs of Fetal Malnutrition, Premature, Nutrition Disorder, Infant
Interventions
DHA
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
24 Hours to 72 Hours
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Intracranial Hemorrhage, Intraventricular Hemorrhage, Cerebral Hypoxia
Interventions
No intervention/treatment is given
Other
Lead sponsor
Nelson Claure
Other
Eligibility
1 Day to 28 Days
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
1
States / cities
Miami, Florida
Conditions
Preterm Delivery, Inadequate Milk Production
Interventions
Merotocin, Placebo
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years to 44 Years · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
10
States / cities
New Haven, Connecticut • South Bend, Indiana • Baltimore, Maryland + 7 more
Conditions
Premature Birth
Interventions
Cervical cerclage, Vaginal progesterone
Procedure · Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Suspended Not applicable Interventional Accepts healthy volunteers

Electrical Inhibition of Human Preterm Contractions

NCT02983240
Conditions
Preterm Labor, PreTerm Birth, Preterm Labor With Delivery Nos
Interventions
Electrical Uterine Pacemaker
Device
Lead sponsor
e-Bio Corp
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Patent Ductus Arteriosus, Preterm Infant, Bronchopulmonary Dysplasia
Interventions
Ibuprofen and acetaminophen, Ibuprofen and placebo
Drug
Lead sponsor
University of South Alabama
Other
Eligibility
5 Days to 21 Days
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Mobile, Alabama
Conditions
Kidney Injury, Pre-Term
Interventions
Caffeine citrate, Placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
12 Hours to 96 Hours
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Madison, Wisconsin
Withdrawn Not applicable Interventional Accepts healthy volunteers

Preventing Preterm Birth With a Pessary

NCT01380158
Conditions
Preterm Birth
Interventions
Cup pessary (Bioteque America, Inc)
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2011
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland