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ClinicalTrials.gov public records Last synced Oct 23, 2026, 6:03 PM EDT

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Showing 121–144 of 334 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Prostheses Clear all
Completed No phase listed Observational Results available

Microbiome and Metagenome in Percutaneous Osseointegrated Prostheses (MMPOP)

NCT02564432
View directory record Official record
Conditions
Transfemoral Amputation
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 19, 2020 · Synced Oct 23, 2026, 6:03 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Influence of 3D Printed Prostheses on Neural Activation Patterns

NCT04110730
View directory record Official record
Conditions
Amniotic Band Syndrome, Upper Extremity Deformities, Congenital
Interventions
3D Printed Upper-limb Prosthesis, Home Intervention
Device · Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
3 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 23, 2026, 6:03 PM EDT
Completed Not applicable Interventional Results available

Hemodynamic Comparison of Tissue Aortic Valves

NCT01635244
View directory record Official record
Conditions
Aortic Valve Stenosis
Interventions
Aortic valve replacement
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 3, 2017 · Synced Oct 23, 2026, 6:03 PM EDT
Completed Not applicable Interventional Results available

Immediate Fit Using Innovative Technology Transtibial & Transfemoral Prosthesis

NCT02886936
View directory record Official record
Conditions
Amputation
Interventions
iFIT Transtibial Prosthesis, iFIT Transfemoral Prosthesis
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 26, 2023 · Synced Oct 23, 2026, 6:03 PM EDT
Completed Not applicable Interventional Results available

Development of Adaptive Vacuum Suspension to Improve Prosthetic Fit and Residual Limb Health

NCT03927404
View directory record Official record
Conditions
Lower Limb Amputation
Interventions
Active vacuum test prosthesis
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 24, 2024 · Synced Oct 23, 2026, 6:03 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

AI-Powered Artificial Vision for Visual Prostheses

NCT06117332
View directory record Official record
Conditions
Blindness, Acquired
Interventions
Visual prosthesis
Device
Lead sponsor
University of California, Santa Barbara
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 23, 2026, 6:03 PM EDT
Completed Not applicable Interventional

SpeakFree Heat and Moisture Exchanger (HME)

NCT05349487
View directory record Official record
Conditions
Laryngeal Cancer, Laryngectomy
Interventions
SpeakFree HME Hands Free Valve, Digital Occlusion, Digital Depression HME
Device · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Oct 23, 2026, 6:03 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Assessment of Gesture Accuracy of a Prosthesis Control System

NCT06446037
View directory record Official record
Conditions
Upper Limb Amputation Below Elbow (Injury)
Interventions
Non-invasive EMG band instrumentation
Device
Lead sponsor
Phantom Neuro Inc.
Industry
Eligibility
21 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Oct 23, 2026, 6:03 PM EDT
Completed Phase 3 Interventional Results available

Core Gel Study of the Safety and Effectiveness of Mentor Round Low Bleed Silicone Gel-filled Mammary Prostheses

NCT00753922
View directory record Official record
Conditions
Breast Reconstruction, Breast Augmentation, Breast Revision
Interventions
Mentor Round Low Bleed Gel-filled Mammary Protheses, both Siltex and Smooth Surface
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,008 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2012
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2014 · Synced Oct 23, 2026, 6:03 PM EDT
Active, not recruiting Not applicable Interventional

Survivorship of Attune Primary Total Knee Prosthesis

NCT01754363
View directory record Official record
Conditions
Noninflammatory Degenerative Joint Disease
Interventions
Attune Primary Total Knee Replacement
Device
Lead sponsor
DePuy International
Industry
Eligibility
22 Years to 75 Years
Enrollment
1,542 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2030
U.S. locations
9
States / cities
Scottsdale, Arizona • Orange, California • DeLand, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 23, 2026, 6:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Observational Examination of Thermoregulation in Total Joint Arthroplasty

NCT02225743
View directory record Official record
Conditions
Hypothermia
Interventions
Observation Of Temperature
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 24, 2019 · Synced Oct 23, 2026, 6:03 PM EDT
Completed Not applicable Interventional Results available

Titan® One Touch Release Inflatable Penile Prosthesis

NCT00731939
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Inflatable Penile Prosthesis
Device
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Male only
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
6
States / cities
Altanta, Georgia • Chicago, Illinois • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2014 · Synced Oct 23, 2026, 6:03 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of a Powered Ankle Prosthesis Capable of Bidirectional Control Via Neural Recording and Cutaneous Stimulation in Free-Space and Walking Tasks

NCT07645729
View directory record Official record
Conditions
Amputation
Interventions
Powered Prosthesis, Prescribed Prosthesis
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 23, 2026, 6:03 PM EDT
Completed Not applicable Interventional

Evaluation of Upper Extremity Prosthesis

NCT00584103
View directory record Official record
Conditions
Transradial Amputation
Interventions
Alpha P Control, Beta P Experimental
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 89 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 8, 2017 · Synced Oct 23, 2026, 6:03 PM EDT
Completed Not applicable Interventional Results available

Clinical Investigation (Beta) of Power Knee Mainstream - Dynamic

NCT04787627
View directory record Official record
Conditions
Prosthesis User, Amputation
Interventions
Power Knee
Device
Lead sponsor
Össur Iceland ehf
Industry
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Silver Spring, Maryland • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Oct 23, 2026, 6:03 PM EDT
Recruiting Not applicable Interventional

Peripheral Interfaces in Amputees for Sensorimotor Integration

NCT04430218
View directory record Official record
Conditions
Upper Extremity Amputee
Interventions
iSens
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2032
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 23, 2026, 6:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Full-arch Monolithic Zirconia ISFDP Follow up

NCT02931968
View directory record Official record
Conditions
Edentulous
Interventions
Monolithic zirconia prosthesis
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 23, 2020 · Synced Oct 23, 2026, 6:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Outcomes With Passive MPKs vs. Powered Prosthetic Knees

NCT05267639
View directory record Official record
Conditions
Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User, Lower Limb Amputation Above Knee (Injury), Amputation; Traumatic, Leg: Thigh, Between Hip and Knee
Interventions
Power Knee
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Holliston, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 23, 2026, 6:03 PM EDT
Completed Not applicable Interventional

Use of Subtle Vibration to Improve Walking Ability by Lower Limb Amputees

NCT00985881
View directory record Official record
Conditions
Amputation, Diabetes Complications
Interventions
Custom prosthetic socket with mechanical vibrators (stochastic resonance), Conventional prosthetic socket (current clinical practice)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 29, 2018 · Synced Oct 23, 2026, 6:03 PM EDT
Recruiting No phase listed Observational

Evaluating the Experience of Upper Limb Prosthesis Use

NCT04855214
View directory record Official record
Conditions
Prosthesis User, Amputation, Upper Limb Amputation at the Wrist, Upper Limb Amputation Above Elbow (Injury), Upper Limb Amputation Below Elbow (Injury)
Interventions
Qualitative Analysis
Other
Lead sponsor
Louis Stokes VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
178 participants
Timeline
2020 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 23, 2026, 6:03 PM EDT
Terminated Not applicable Interventional Results available

Ascension® Post- Approval Study; PyroCarbon Metacarpophalangeal Total Joint Prosthesis

NCT02408471
View directory record Official record
Conditions
Rheumatoid Arthritis, Systemic Lupus Erythematosus, Osteoarthritis, Post-traumatic Arthritis
Interventions
Ascension® MCP Finger Implant
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2015
U.S. locations
9
States / cities
Tucson, Arizona • Bloomington, Indiana • Carmel, Indiana + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2023 · Synced Oct 23, 2026, 6:03 PM EDT
Completed Not applicable Interventional

Oral Antibiotics After 2-Stage Revision for Infected Total Hip Arthroplasty and Total Knee Arthroplasty

NCT01760863
View directory record Official record
Conditions
Prosthesis-Related Infections
Interventions
Oral Antibiotics
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
4
States / cities
Chicago, Illinois • Winfield, Illinois • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Oct 23, 2026, 6:03 PM EDT
Completed Not applicable Interventional Results available

Evaluation of a Modified Running-specific Prosthetic Foot

NCT02440711
View directory record Official record
Conditions
Transtibial Amputation
Interventions
Energy storing foot (ESF), Modified running specific foot (mRSF)
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Oct 23, 2026, 6:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neural Prostheses and Gait Performance: Model-Based Strategies

NCT00991406
View directory record Official record
Conditions
Hemiplegia
Interventions
FES
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 9, 2019 · Synced Oct 23, 2026, 6:03 PM EDT