- Conditions
- Cystic Fibrosis
- Interventions
- Standard Dose YPT-01, Placebo
- Drug · Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
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Showing 25–48
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- Conditions
- Cystic Fibrosis, Chronic Bronchitis
- Interventions
- IV amikacin, PO azithromycin, IV ceftazidime, PO ciprofloxacin, IV meropenem, IV piperacillin-tazobactam, IV ticarcillin-clavulanate, IV tobramycin
- Drug
- Lead sponsor
- Seattle Children's Hospital
- Other
- Eligibility
- 14 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2007
- U.S. locations
- 8
- States / cities
- Iowa City, Iowa • St Louis, Missouri • Cincinnati, Ohio + 4 more
- Conditions
- Surgical Procedure, Unspecified
- Interventions
- Personalized Body-Worn Alcohol Dispenser
- Device
- Lead sponsor
- University of Iowa
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 39 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Drug Resistance, Microbial
- Interventions
- None - Observational study
- Other
- Lead sponsor
- Maimonides Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- Brooklyn, New York
- Conditions
- Bacteremia
- Interventions
- Not listed
- Lead sponsor
- T2 Biosystems
- Industry
- Eligibility
- 18 Years to 95 Years
- Enrollment
- 156 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Camden, New Jersey
- Conditions
- Cystic Fibrosis
- Interventions
- Piperacillin-tazobactam combination product
- Drug
- Lead sponsor
- West Virginia University
- Other
- Eligibility
- 8 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Morgantown, West Virginia
- Conditions
- Bacterial Disease Carrier, Cystic Fibrosis
- Interventions
- Placebo, WRAIR-PAM-CF1
- Other · Biological
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years and older
- Enrollment
- 73 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 19
- States / cities
- Tucson, Arizona • La Jolla, California • Los Angeles, California + 15 more
- Conditions
- Cystic Fibrosis
- Interventions
- Not listed
- Lead sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
- NIH
- Eligibility
- 9 Years to 65 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2008
- U.S. locations
- 2
- States / cities
- Bethesda, Maryland • Milwaukee, Wisconsin
- Conditions
- Pseudomonas Aeruginosa in Cystic Fibrosis
- Interventions
- TOBI® PODHALER®, TOBI®, Bethkis®, Cayston®
- Drug
- Lead sponsor
- Mylan Inc.
- Industry
- Eligibility
- 6 Years and older
- Enrollment
- 409 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2021
- U.S. locations
- 47
- States / cities
- Anchorage, Alaska • Little Rock, Arkansas • Bellflower, California + 43 more
- Conditions
- Pneumonia
- Interventions
- Murepavadin, One anti-pseudomonal antibiotic
- Drug
- Lead sponsor
- Polyphor Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa • Pittsburgh, Pennsylvania
- Conditions
- Cystic Fibrosis
- Interventions
- azithromycin 250 mg tablets, placebo tablets
- Drug
- Lead sponsor
- CF Therapeutics Development Network Coordinating Center
- Network
- Eligibility
- 6 Years to 18 Years
- Enrollment
- 263 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 31
- States / cities
- Phoenix, Arizona • Hartford, Connecticut • Atlanta, Georgia + 27 more
- Conditions
- Cystic Fibrosis
- Interventions
- KB001-A, Placebo Comparator
- Biological · Drug
- Lead sponsor
- Humanigen, Inc.
- Industry
- Eligibility
- 12 Years to 50 Years
- Enrollment
- 182 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 58
- States / cities
- Mobile, Alabama • Phoenix, Arizona • Tucson, Arizona + 52 more
- Conditions
- Chronic Pseudomonas Aeruginosa Infection, Cystic Fibrosis (CF)
- Interventions
- BX004, Placebo
- Biological · Other
- Lead sponsor
- BiomX Ltd
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 14
- States / cities
- Birmingham, Alabama • Anchorage, Alaska • Little Rock, Arkansas + 11 more
- Conditions
- Cystic Fibrosis
- Interventions
- Inhaled AR-501, Inhaled Placebo
- Drug
- Lead sponsor
- Aridis Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years to 49 Years
- Enrollment
- 102 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2023
- U.S. locations
- 25
- States / cities
- Tucson, Arizona • Long Beach, California • Denver, Colorado + 22 more
- Conditions
- Infections Resistant to Multiple Drugs, Bacterial Infections
- Interventions
- Standard of Care
- Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- Not listed
- Enrollment
- 6,496 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Cystic Fibrosis
- Interventions
- AZLI 75 mg three times a day (TID), Placebo three times a day (TID)
- Drug
- Lead sponsor
- Gilead Sciences
- Industry
- Eligibility
- 6 Years and older
- Enrollment
- 166 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 40
- States / cities
- Birmingham, Alabama • Anchorage, Alaska • Phoenix, Arizona + 37 more
- Conditions
- Non Cystic Fibrosis Bronchiectasis
- Interventions
- Ciprofloxacin dispersion for inhalation, Placebo
- Drug
- Lead sponsor
- Aradigm Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 278 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 30
- States / cities
- Peoria, Arizona • Phoenix, Arizona • Downey, California + 27 more
- Conditions
- Pneumonia, Hematologic Malignancy, Pseudomonas Aeruginosa Infection, Bacteremia, Hematopoietic Stem Cell Transplant (HSCT)
- Interventions
- Ceftolozane / Tazobactam Injection
- Drug
- Lead sponsor
- Weill Medical College of Cornell University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Surgical Wound Infection, Cross Infection
- Interventions
- SafeHaven Automated Hand Hygiene Device
- Device
- Lead sponsor
- Oregon Health and Science University
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Portland, Oregon
- Conditions
- Cystic Fibrosis, Pneumonia, Pseudomonas Aeruginosa Infection
- Interventions
- meropenem
- Drug
- Lead sponsor
- Joseph Kuti
- Other
- Eligibility
- 6 Years to 17 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 7
- States / cities
- Hartford, Connecticut • Indianapolis, Indiana • New York, New York + 4 more
- Conditions
- Cystic Fibrosis, Lung Disease, Pseudomonas Infections
- Interventions
- CF newborn screening
- Procedure
- Lead sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- NIH
- Eligibility
- 1 Month to 21 Years
- Healthy volunteers
- Healthy volunteers not accepted
- U.S. locations
- 2
- States / cities
- Madison, Wisconsin • Milwaukee, Wisconsin
- Conditions
- Cystic Fibrosis, Cystic Fibrosis Pulmonary Exacerbation, Pseudomonas Aeruginosa Infection
- Interventions
- Ceftolozane/Tazobactam
- Drug
- Lead sponsor
- Joseph L. Kuti, PharmD
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 4
- States / cities
- Hartford, Connecticut • Indianapolis, Indiana • Chapel Hill, North Carolina + 1 more
- Conditions
- Pneumonia
- Interventions
- Murepavadin, Two anti-pseudomonal antibiotics
- Drug
- Lead sponsor
- Polyphor Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 41 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 3
- States / cities
- Chicago, Illinois • Springfield, Missouri • Greensboro, North Carolina
- Conditions
- Cystic Fibrosis
- Interventions
- Throat Swab
- Procedure
- Lead sponsor
- Tufts Medical Center
- Other
- Eligibility
- 1 Day to 3 Months
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2011
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts