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ClinicalTrials.gov public records Last synced Nov 14, 2026, 7:09 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 202 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Reduced Physical Activity Clear all

Conditions: Cardiovascular Risk Factor, Health Behavior, Physical Activity, Self Efficacy, Vascular Stiffness
Interventions: Education, Physical Activity, and Stress Management Program, Wait-list; Behavioral · Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 40 Years to 60 Years · Female only
Enrollment: 49 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: ketone ester, placebo; Dietary Supplement
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Overweight and Obesity
Interventions: Nutrigenomix, personalized dietary plan, Physical Activity, Behavioral counseling, Standard Dietary plan; Behavioral
Lead sponsor: Augusta University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 125 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: HFrEF - Heart Failure With Reduced Ejection Fraction
Interventions: Baroreflex Activation Therapy; Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 7
States / cities: San Francisco, California • Washington D.C., District of Columbia • Chicago, Illinois + 2 more

Conditions: Prior Acute Myocardial Infarction, Evidence of Systemic Inflammation (C Reactive Protein Plasma >2 mg/l), Reduced Left Ventricle Ejection Fraction (<50%), Symptoms of Heart Failure (NYHA Class II-III)
Interventions: Cardiopulmonary exercise test, Echocardiogram; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 110 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Discoid Lupus Erythematosus
Interventions: Placebo, Daxdilimab; Drug
Lead sponsor: Amgen; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 16
States / cities: North Little Rock, Arkansas • Beverly Hills, California • Fremont, California + 12 more

Conditions: Obesity &Amp; Overweight
Interventions: HealthyWE; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 19 Years and older
Enrollment: 89 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Camden, New Jersey

Conditions: Anterior Knee Pain Syndrome
Interventions: Knee Isometric Program (KIP); Behavioral
Lead sponsor: The Methodist Hospital Research Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Childhood Obesity
Interventions: Healthy Toddler Parent Group (HTPG), Families Understanding Nutrition and Physically Active Lifestyles (FUNPALs) Playgroup; Behavioral
Lead sponsor: University of Houston; Other
Eligibility: 18 Months to 36 Months
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Heart Failure With Reduced Ejection Fraction (HFrEF)
Interventions: Extra-virgin olive oil; Other
Lead sponsor: Old Dominion University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Norfolk, Virginia

Conditions: Metabolic Syndrome
Interventions: Rimonabant, Placebo (for Rimonabant), Mild hypocaloric diet; Drug · Other
Lead sponsor: Sanofi; Industry
Eligibility: 35 Years to 70 Years
Enrollment: 254 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Bridgewater, New Jersey

Conditions: Shoulder
Interventions: Cervical retraction exercise; Other
Lead sponsor: Sacred Heart University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Fairfield, Connecticut

Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: Omecamtiv Mecarbil, Placebo; Drug
Lead sponsor: Cytokinetics; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 276 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 36
States / cities: Anchorage, Alaska • Little Rock, Arkansas • Torrance, California + 31 more

Conditions: Cardiovascular Diseases, Heart Diseases, Obesity
Interventions: Exercise; Procedure
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years to 75 Years
Enrollment: 162 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Cardiovascular Diseases
Interventions: Walking Program + Motivational Interviewing Calls, Walking Program + Automated Calls, Walking Program; Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 40 Years to 65 Years · Female only
Enrollment: 288 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 7
States / cities: Chicago, Illinois • Oak Park, Illinois

Conditions: Health Promotion
Interventions: Nutrition and physical activity program; Behavioral
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 680 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2004
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Major Depressive Disorder
Interventions: Not listed
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2005
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Aging, Cardiovascular Disease, Diabetes Mellitus
Interventions: Caloric Restriction (CR), Exercise; Behavioral
Lead sponsor: National Institute on Aging (NIA); NIH
Eligibility: 25 Years to 50 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2006
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Diabetes
Interventions: Live Well, Be Well; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 25 Years and older
Enrollment: 230 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Hypertension
Interventions: Dietary and physical activity JITAI delivered through the myBPmyLife app, Control Group; Behavioral · Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 608 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 2
States / cities: Ann Arbor, Michigan • Flint, Michigan

Conditions: Lifestyle Risk Reduction, Adolescent Health, Family Health, Cardio-metabolic Health, Mental Health, Wellness Program, Type 2 Diabetes, Obesity, Adolescent
Interventions: Mindfulness-Based Intervention, Parent Education, Physical Activity, Brief Mindfulness Intervention for Parents, Preschool Curriculum, Nutrition and Cooking Education; Behavioral
Lead sponsor: Colorado State University; Other
Eligibility: 11 Years and older
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Fort Collins, Colorado

Conditions: Physical Inactivity, Vascular Dysfunction, Skeletal Muscle Atrophy
Interventions: Sauna, Reduced Physical Activity; Device · Behavioral
Lead sponsor: Brigham Young University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Provo, Utah

Conditions: Aging
Interventions: Caloric Restriction (CR); Behavioral
Lead sponsor: National Institute on Aging (NIA); NIH
Eligibility: 25 Years to 50 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2004
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Malignant Neoplasm of Breast
Interventions: Mind-Body Exercises, Questionnaires; Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Search by objective public record fields.

Reducing Cardiovascular Disease Risk in Perimenopausal Latinas

Ketones in Heart Failure With Reduced Ejection Fraction

Lifestyle Intervention for Healthy Change

Impact of Barostimulation on Hemodynamics in Adults With Heart Failure

Interleukin-1 Blockade With Canakinumab to Improve Exercise Capacity in Patients With Chronic Systolic Heart Failure and Elevated High Sensitivity C-reactive Protein (Hs-CRP)

Study of Daxdilimab (HZN-7734) in Participants With Moderate-to-Severe Primary Discoid Lupus Erythematosus

HealthyWE: Achieving a Healthy Weight and Reducing Pain

Knee Isometric Program (KIP) Home Exercise Programs (HEP) Physical Therapy (PT) Study

Reducing Obesity Through Play Among Toddlers: Tiny Steps to Health (TSHS) Study

Olive Oil Supplementation for Heart Failure With Reduced Ejection Fraction

VIsceral Fat Reduction Assessed by CT-scan On RImonabAnt

Impact of Cervical Exercises During Simulated Game on Throwing Shoulder Motion and Strength

Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure

Effect of Exercise on Elevated C-reactive Protein Concentrations in Formerly Inactive Adults

Women's Walking Program

Improving Health in Low Income Women Following the Birth of a Child

Treatment of Reduced Heart Rate Variability Associated With Major Depression With Electroconvulsive Therapy

CALERIE (PBRC, Baton Rouge) - Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy

Reducing Disparities in Diabetes Risk Through Lifestyle Changes in Community Settings

Improving Blood Pressure Control Through the myBPmyLife mHealth Application

Health Without Barriers/Salud Sin Barreras- Northern Colorado

Heat Therapy During Reduced Physical Activity

CALERIE (Tufts) - Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy

An Early Stress-Reduction Intervention in Patients With Newly Diagnosed Breast Cancer