Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:18 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Refractive Surgery Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery

NCT07078799
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
LASIK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 59 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Jul 22, 2026, 2:18 AM EDT
Completed No phase listed Observational

Accuracy of IOLMASTER 700 Total Keratometry (TK)

NCT05254587
View directory record Official record
Conditions
Myopia, Hyperopia, Cataract
Interventions
IOLMASTER 700 TK
Device
Lead sponsor
Advanced Vision Care
Other
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
7
States / cities
Bakersfield, California • Los Angeles, California • Torrance, California + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Jul 22, 2026, 2:18 AM EDT
Completed No phase listed Observational

Evaluation of the Aspheric ReSTOR Intraocular Lens (IOL) After Routine Cataract Extraction

NCT00565695
View directory record Official record
Conditions
Cataract Extraction, Refractive Surgery
Interventions
aspheric ReSTOR multifocal intraocular lens (IOL)
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
40 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 3, 2010 · Synced Jul 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Topography-guided LASIK Surgery

NCT03292419
View directory record Official record
Conditions
Myopia
Interventions
Topography-guided LASIK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 59 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Jul 22, 2026, 2:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Screening Aid to Identify Corneas That May Have Pathologies or Other Conditions

NCT00396188
View directory record Official record
Conditions
Corneal Diseases
Interventions
Not listed
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
18 Years and older
Enrollment
769 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
4
States / cities
La Jolla, California • San Diego, California • Greenwood Village, Colorado + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 16, 2015 · Synced Jul 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Results available

Clinical Study to Evaluate the Safety and Effectiveness of the RxSight Light Adjustable Lens (LAL) in Subjects With Prior Corneal Refractive Surgery

NCT03660865
View directory record Official record
Conditions
Aphakia, Cataract
Interventions
Light Adjustable lens (LAL) and Light Delivery Device (LDD), Control IOL
Device
Lead sponsor
RxSight, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
6
States / cities
Leawood, Kansas • Brecksville, Ohio • Sioux Falls, South Dakota + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2021 · Synced Jul 22, 2026, 2:18 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Contralateral Study of Topography Guided LASIK Versus Small Incision Lenticule Extraction

NCT05611294
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Topography Guided LASIK Surgery, Small Incision Lenticule Extraction Surgery
Device
Lead sponsor
Hoopes Vision
Other
Eligibility
22 Years to 50 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Draper, Utah
Source: ClinicalTrials.gov public record
Updated Jul 31, 2024 · Synced Jul 22, 2026, 2:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Quality of Vision and Quality of Life With LASIK

NCT02161263
View directory record Official record
Conditions
Myopia, Astigmatism, Quality of Lifte
Interventions
Patient Quality of Life andVision after LASIK Surgery
Other
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Jul 22, 2026, 2:18 AM EDT
Completed No phase listed Observational

Refractive and Visual Outcomes With the ARGOS Biometer In Eyes With a History of Refractive Surgery: ARGOS Study

NCT07129980
View directory record Official record
Conditions
Cataract
Interventions
ARGOS Biometer
Device
Lead sponsor
Vance Thompson Vision
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Jul 22, 2026, 2:18 AM EDT
Recruiting Phase 4 Interventional

Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery

NCT07140653
View directory record Official record
Conditions
Astigmatism
Interventions
Femto arcs, Light Adjustable Lens (LAL)
Other · Device
Lead sponsor
Center For Sight
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Venice, Florida • Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Jul 22, 2026, 2:18 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Long-term Effects of Laser Refractive Surgery

NCT00350246
View directory record Official record
Conditions
Myopia
Interventions
Laser Refractive Surgery
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 27, 2010 · Synced Jul 22, 2026, 2:18 AM EDT
Completed Phase 4 Interventional

Refractive Surgery and Optive Compatibility Study

NCT00469157
View directory record Official record
Conditions
Dry Eye Syndromes
Interventions
Optive
Drug
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2008 · Synced Jul 22, 2026, 2:18 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Anesthetic Impregnated Bandage Soft Contact Lens (BSCL) in Pain Management After Photorefractive Keratectomy (PRK)

NCT04283331
View directory record Official record
Conditions
Myopia, Hypermetropia, Refractive Errors, Astigmatism
Interventions
Proparacaine Ophthalmic
Drug
Lead sponsor
Beeran Meghpara, MD
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Jul 22, 2026, 2:18 AM EDT
Completed Phase 4 Interventional

A Study of Interventions to Reduce Disability From Visual Loss in Nursing Home Residents

NCT00348621
View directory record Official record
Conditions
Cataract, Refractive Error, Low Vision
Interventions
Visual impairment intervention program
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
2,544 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2002
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Jul 22, 2026, 2:18 AM EDT
Completed No phase listed Observational Results available

The Accuracy of Flap Thickness Versus the Pre-determined Surgical Planning Using WaveLight® FS200

NCT05501795
View directory record Official record
Conditions
Myopia
Interventions
WaveLight® FS200 femtosecond laser
Device
Lead sponsor
Stephen Wexler
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Bismarck, North Dakota
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Jul 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Prospective, Contralateral, Eye to Eye Comparison of SMILE Surgery to LASIK Surgery

NCT03067077
View directory record Official record
Conditions
Myopia
Interventions
SMILE, LASIK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 59 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2022 · Synced Jul 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Effectiveness Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Hyperopia

NCT00762281
View directory record Official record
Conditions
Hyperopia
Interventions
MEL 80 Hyperopic LASIK Treatment
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
21 Years and older
Enrollment
189 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
6
States / cities
San Diego, California • Greenwood Village, Colorado • Kansas City, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2012 · Synced Jul 22, 2026, 2:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Clinical and Refractive Outcomes After Contoura® Refractive Surgery Planned Using Phorcides Surgery Planning Software

NCT04495829
View directory record Official record
Conditions
Refractive Errors
Interventions
Phorcides Analytical Engine
Device
Lead sponsor
American Corneal Consultants
Other
Eligibility
20 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
5
States / cities
Atlanta, Georgia • Coon Rapids, Minnesota • Chesterfield, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2023 · Synced Jul 22, 2026, 2:18 AM EDT
Terminated Not applicable Interventional Results available

Topo-guided LASIK and Photorefractive Keratectomy vs Wavefront LASIK and Photorefractive Keratectomy

NCT03075176
View directory record Official record
Conditions
Surgery, Myopia
Interventions
Wavefront optimized LASIK, Wavefront optimized Photorefractive Keratectomy, Topography-guided LASIK, Topography-guided Photorefractive Keratectomy
Device
Lead sponsor
University of Utah
Other
Eligibility
21 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Jul 16, 2023 · Synced Jul 22, 2026, 2:18 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

CONTOURA vs WFO Ablation PRK & LASIK

NCT05037370
View directory record Official record
Conditions
Refractive Surgery
Interventions
Wave-Front Optimized (WFO) ablation vs Topography-guided (TG) ablation
Device
Lead sponsor
59th Medical Wing
Federal
Eligibility
21 Years to 50 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Jul 22, 2026, 2:18 AM EDT
Withdrawn No phase listed Observational

Accuracy of the Pentacam and IOL Master to Calculate the Effective Corneal Power After Corneal Refractive Surgery

NCT00466908
View directory record Official record
Conditions
Cataract Extraction, Refractive Surgery
Interventions
Pentacam and IOL Master
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
40 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 5, 2018 · Synced Jul 22, 2026, 2:18 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

SMILE (Small Incision Lenticule Extraction) in the DoD (Department of Defense)

NCT04072289
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Visumax spherocylindrical treatment
Device
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
22 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2022 · Synced Jul 22, 2026, 2:18 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluate the Safety and Effectiveness of the AccuraSee™ IOPCL for Secondary Implantation in the Capsular Bag to Improve Near and/or Intermediate Vision Following Previous Cataract Surgery

NCT06625749
View directory record Official record
Conditions
Refractive Surgery, Refractive Error - Myopia
Interventions
Accurasee™ IOPCL
Device
Lead sponsor
OnPoint Vision Inc
Industry
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Jul 22, 2026, 2:18 AM EDT