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ClinicalTrials.gov public records Last synced Sep 9, 2026, 12:31 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Optical Coherence Tomography, Refractive Errors, Myopia
Interventions
Optical coherence tomography
Diagnostic Test
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Conditions
Aphakia, Cataract
Interventions
Light Adjustable lens (LAL) and Light Delivery Device (LDD), Control IOL
Device
Lead sponsor
RxSight, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
6
States / cities
Leawood, Kansas • Brecksville, Ohio • Sioux Falls, South Dakota + 3 more
Completed No phase listed Observational Accepts healthy volunteers

Novel Diagnostics With Optical Coherence Tomography: Imaging the Anterior Eye

NCT00343473
Conditions
Fuch's Dystrophy, Corneal Disorders, Prior Surgery
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2024
U.S. locations
2
States / cities
New York, New York • Pittsburgh, Pennsylvania
Not yet recruiting No phase listed Observational Accepts healthy volunteers

UNITY DX Cornea Study

NCT07768735
Conditions
Tomography
Interventions
UNITY DX, ANTERION
Device
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Hyperopia
Interventions
MEL 80 Hyperopic LASIK Treatment
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
21 Years and older
Enrollment
189 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
6
States / cities
San Diego, California • Greenwood Village, Colorado • Kansas City, Missouri + 3 more
Conditions
Refractive Error
Interventions
Intraoperative Autorefractor IAR-1, Hartmann-Shack Auto Refractor
Device
Lead sponsor
Adventus Technology
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Myopia
Interventions
Photorefractive Keratectomy (PRK)
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Presbyopia
Interventions
Mitomycin C, Raindrop Near Vision Inlay
Drug · Device
Lead sponsor
Fichte, Endl & Elmer Eyecare
Other
Eligibility
41 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Amherst, New York
Conditions
Dry Eye
Interventions
Lifitegrast
Drug
Lead sponsor
MDbackline, LLC
Other
Eligibility
Not listed
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Laguna Hills, California
Conditions
Unstable Corneas
Interventions
Epithelium-On Riboflavin, Epithelium-Off Riboflavin, UV Light - Continuous Beam, UV Pulsed Beam
Drug · Device
Lead sponsor
Crowd Health Research, LTD
Other
Eligibility
12 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
16
States / cities
Santa Rosa, California • Denver, Colorado • Jacksonville, Florida + 13 more
Completed Phase 4 Interventional Accepts healthy volunteers

Long-term Effects of Laser Refractive Surgery

NCT00350246
Conditions
Myopia
Interventions
Laser Refractive Surgery
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Aphakia, Astigmatism, Presbyopia
Interventions
Clareon Vivity IOL - Non Toric, Clareon Vivity IOL - Toric, Clareon PanOptix Trifocal IOL - Non Toric, Clareon PanOptix Trifocal IOL - Toric
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
6
States / cities
Torrance, California • Jacksonville, Florida • Liverpool, New York + 3 more
Completed Not applicable Interventional Accepts healthy volunteers

Wavefront-guided vs. Topography-guided LASIK

NCT05588882
Conditions
Myopia
Interventions
Wavefront-guided LASIK, Wavefront-guided
Procedure
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 59 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Surgery, Myopia
Interventions
Wavefront optimized LASIK, Wavefront optimized Photorefractive Keratectomy, Topography-guided LASIK, Topography-guided Photorefractive Keratectomy
Device
Lead sponsor
University of Utah
Other
Eligibility
21 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Murray, Utah
Conditions
Cataract, Presbyopia
Interventions
Neutral Aspheric Monofocal IOL, Negative Aspheric Monofocal IOL
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 95 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Hershey, Pennsylvania
Conditions
Astigmatism
Interventions
CATARACT SURGERY
Procedure
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Terminated No phase listed Interventional Accepts healthy volunteers Results available

Whole Eye Optical Coherence Tomography (OCT) to Improve Refractive Surgery and Eye Care

NCT03219567
Conditions
Image, Body
Interventions
Optical Coherence Tomography (OCT), Magnetic resonance imaging (MRI)
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Myopia, Astigmatism
Interventions
Ray tracing guided LASIK surgery
Device
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 59 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Palo Alto, California
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Impact of a Novel Extended Depth of Focus Intraocular Lens on Visual and Lifestyle Enhancement

NCT04570579
Conditions
Cataract, Cataract Senile, Presbyopia
Interventions
Vivity Extended Depth of Focus Intraocular Lens
Device
Lead sponsor
Alanna Nattis, DO
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Babylon, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Prospective, Contralateral, Eye to Eye Comparison of SMILE Surgery to LASIK Surgery

NCT03067077
Conditions
Myopia
Interventions
SMILE, LASIK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 59 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Completed No phase listed Observational Accepts healthy volunteers

Lacritin and Heparanase Levels in Human Tears After Laser Refractive Surgery

NCT01049724
Conditions
Myopia
Interventions
Tear collection
Other
Lead sponsor
Fort Belvoir Community Hospital
Federal
Eligibility
21 Years to 55 Years
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Fort Belvoir, Virginia
Conditions
Myopia, Astigmatism
Interventions
LASIK with the iFS femtosecond laser
Procedure
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2018
U.S. locations
1
States / cities
Stanford, California
Completed No phase listed Observational Accepts healthy volunteers

Quality of Vision and Quality of Life With LASIK

NCT02161263
Conditions
Myopia, Astigmatism, Quality of Lifte
Interventions
Patient Quality of Life andVision after LASIK Surgery
Other
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Completed Not applicable Interventional Accepts healthy volunteers

Corneal Biomechanics With Hydration in Normal and LASIK Eyes

NCT01183702
Conditions
Laser Corneal Surgery
Interventions
LASIK surgery, No Intervention
Procedure · Other
Lead sponsor
Deb Grzybowski
Other
Eligibility
18 Years to 60 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2012
U.S. locations
1
States / cities
Columbus, Ohio