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ClinicalTrials.gov public records Last synced Oct 26, 2026, 10:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 505–528 of 8,252 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Risk Clear all
Recruiting Phase 2 Interventional

Orexin Antagonism for Suicide Risk: A Proof-of-Concept Clinical Trial

NCT06854224
View directory record Official record
Conditions
Suicide Risk, Major Depressive Disorder (MDD)
Interventions
Suvorexant (dual orexin receptor antagonist)
Drug
Lead sponsor
Marianne Goodman
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Oct 26, 2026, 10:18 PM EDT
Not listed Phase 2 Interventional

A Study of Therapeutic Iobenguane (131-I) and Vorinostat for Recurrent or Progressive High-Risk Neuroblastoma Subjects

NCT03561259
View directory record Official record
Conditions
Neuroblastoma, Neuroectodermal Tumors, Neoplasms
Interventions
131I-MIBG, 131-MIBG + Vorinostat
Drug
Lead sponsor
Jubilant DraxImage Inc.
Industry
Eligibility
1 Year and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
21
States / cities
Palo Alto, California • San Francisco, California • Aurora, Colorado + 17 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Oct 26, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Canola Oil Multi-center Intervention Trial II

NCT03054779
View directory record Official record
Conditions
Cardiovascular Disease, Metabolic Syndrome
Interventions
Canola Oil, High oleic acid canola oil, Western diet oil combination
Other
Lead sponsor
Penn State University
Other
Eligibility
20 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 26, 2026, 10:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessing the Link Between Smoke Carcinogen Biomarkers and Lung Cancer Risk - 1

NCT00218179
View directory record Official record
Conditions
Tobacco Use Disorder, Lung Cancer
Interventions
Non-intervention
Other
Lead sponsor
University of Minnesota
Other
Eligibility
55 Years to 74 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Oct 26, 2026, 10:18 PM EDT
Recruiting Phase 1Phase 2 Interventional

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

NCT05849662
View directory record Official record
Conditions
Leukemia, Juvenile Myelomonocytic, JMML, JCML, Neurofibromatosis 1, CBL Syndrome
Interventions
Trametinib, Azacitidine, Fludarabine, Cytarabine
Drug
Lead sponsor
Therapeutic Advances in Childhood Leukemia Consortium
Other
Eligibility
1 Month to 21 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
21
States / cities
Phoenix, Arizona • Los Angeles, California • San Francisco, California + 18 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 26, 2026, 10:18 PM EDT
Completed Phase 1 Interventional

Study of Roflumilast in Combination With Standard Chemotherapy for High-risk Diffuse Large B-cell Lymphoma

NCT03458546
View directory record Official record
Conditions
Lymphoma, B-Cell
Interventions
Roflumilast
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Oct 26, 2026, 10:18 PM EDT
Completed No phase listed Observational

Vascular Subphenotypes of Lung Disease in HIV & COPD

NCT01581086
View directory record Official record
Conditions
Pulmonary Artery Hypertension
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Oct 26, 2026, 10:18 PM EDT
Recruiting Phase 2 Interventional

Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial

NCT06499870
View directory record Official record
Conditions
Prostate Adenocarcinoma
Interventions
Biopsy, Biospecimen Collection, Computed Tomography, Enzalutamide, Fluorine F 18 Piflufolastat, Image Guided Radiation Therapy, Magnetic Resonance Imaging, Positron Emission Tomography, Questionnaire Administration, Relugolix
Procedure · Drug · Other + 1 more
Lead sponsor
Sean Sachdev
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2032
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 26, 2026, 10:18 PM EDT
Terminated Phase 2 Interventional Results available

Sodium Nitrite in Lung Transplant Patients to Minimize the Risk of Pulmonary Graft Dysfunction

NCT01715883
View directory record Official record
Conditions
Primary Graft Dysfunction
Interventions
Sodium Nitrite
Drug
Lead sponsor
Gladwin, Mark, MD
Individual
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Oct 26, 2026, 10:18 PM EDT
Active, not recruiting Phase 2 Interventional

Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Malignant Salivary Gland Tumors That Have Been Removed By Surgery

NCT01220583
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
cisplatin, 3-dimensional conformal radiation therapy, intensity-modulated radiation therapy
Drug · Radiation
Lead sponsor
Radiation Therapy Oncology Group
Network
Eligibility
18 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2031
U.S. locations
259
States / cities
Birmingham, Alabama • Gilbert, Arizona • Peoria, Arizona + 196 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 26, 2026, 10:18 PM EDT
Completed Not applicable Interventional Results available

Digihaler in Chronic Obstructive Pulmonary Disease (COPD)

NCT05241288
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Albuterol eMDPI DS
Combination Product
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
40 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Oct 26, 2026, 10:18 PM EDT
Recruiting Phase 2 Interventional

Orphan Indications for CD19 Redirected Autologous T Cells

NCT04276870
View directory record Official record
Conditions
Pediatric and Young Adult Patientswith Hypodiploid or t(17;19) B-ALL, Infants With Very High Risk KMT2A B-ALL, Patients With Central Nervous System Relapse Who Did Not Receive Cranial Radiation or Bone Marrow Transplantation
Interventions
Murine CART19
Biological
Lead sponsor
Stephan Grupp MD PhD
Other
Eligibility
0 Years to 29 Years
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2037
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 26, 2026, 10:18 PM EDT
Enrolling by invitation No phase listed Observational

Evaluation of Step-Based Care for Individuals at Clinical High Risk for Psychosis

NCT03970005
View directory record Official record
Conditions
Prodromal Schizophrenia
Interventions
Step-Based Care Model
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
12 Years to 25 Years
Enrollment
100 participants
Timeline
2019 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 26, 2026, 10:18 PM EDT
Terminated Phase 4 Interventional

ACTIONS - Aortic Counterpulsation to Improve Outcomes in Noncardiac Surgery

NCT01253356
View directory record Official record
Conditions
Patients With History of Ischemic Heart Disease With LV Dysfunction Undergoing Noncardiac Surgery
Interventions
IABP
Device
Lead sponsor
Datascope Corp.
Industry
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Davenport, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 6, 2012 · Synced Oct 26, 2026, 10:18 PM EDT
Terminated No phase listed Observational

Data Collection and Analysis of Patients Who Have Had an Electrophysiological Procedure

NCT00825968
View directory record Official record
Conditions
Heart Disease, Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Emile Daoud
Other
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 20, 2011 · Synced Oct 26, 2026, 10:18 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers Results available

Study to Test Sensitivity and Specificity of Passive Wave Pressure Device in Determining Ischemic Stroke

NCT01643525
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Nautilus NeuroWaveTM System
Device
Lead sponsor
Jan Medical, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
3
States / cities
Baltimore, Maryland • Columbia, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 8, 2024 · Synced Oct 26, 2026, 10:18 PM EDT
Completed Not applicable Interventional

Dulce Digital-Project Dulce 2.0 Texting Study

NCT01749176
View directory record Official record
Conditions
Diabetes
Interventions
SMS texting intervention, Control-Usual Care
Behavioral
Lead sponsor
Scripps Whittier Diabetes Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Escondido, California
Source: ClinicalTrials.gov public record
Updated Nov 19, 2014 · Synced Oct 26, 2026, 10:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nourish: A Digital Health Program to Promote the DASH Eating Plan Among Adults With High Blood Pressure

NCT03875768
View directory record Official record
Conditions
Hypertension, Health Behavior
Interventions
Tracking plus coaching
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
301 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 16, 2024 · Synced Oct 26, 2026, 10:18 PM EDT
Not listed Not applicable Interventional

Alerting Providers at Patient Hospital Discharge to Consider Prescribing Rivaroxaban to Reduce Venous Thromboembolism

NCT06232551
View directory record Official record
Conditions
Venous Thromboembolic Disease, Pulmonary Embolism and Thrombosis, Deep Vein Thrombosis, Hospitalism
Interventions
EHR (electronic health record) alert, No EHR (electronic health record) alert
Other
Lead sponsor
Scott C. Woller, MD
Other
Eligibility
18 Years to 110 Years
Enrollment
152,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Oct 26, 2026, 10:18 PM EDT
Withdrawn No phase listed Observational

An Observational Study of Early Coagulopathy, or Clotting Disorder, in Injured Patients

NCT00744003
View directory record Official record
Conditions
Trauma-induced Coagulopathy
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 18, 2013 · Synced Oct 26, 2026, 10:18 PM EDT
Completed Not applicable Interventional

Parent Perceptions of Weight Status: Impact of a Pilot Intervention

NCT00867373
View directory record Official record
Conditions
Obesity
Interventions
Education Intervention
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
3 Years to 13 Years
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 26, 2013 · Synced Oct 26, 2026, 10:18 PM EDT
Completed Not applicable Interventional Results available

Singing and Cardiovascular Health in Older Adults

NCT04121741
View directory record Official record
Conditions
Cardiovascular Diseases, Cardiovascular Risk Factor, Cardiovascular Health
Interventions
Singing with Music Therapist, Singing with Guided Video, Control Arm
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
55 Years to 79 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 26, 2026, 10:18 PM EDT
Withdrawn Phase 1Phase 2 Interventional

Clinical Trial of BP1001 (Liposomal Grb2 Antisense Oligonucleotide) in Combination With Dasatinib in Patients With Ph + CML Who Have Failed TKI, Ph+ AML, Ph+ MDS

NCT02923986
View directory record Official record
Conditions
Chronic Myelogenous Leukemia, Ph1-Positive, Acute Myeloid Leukemia, Myelodysplastic Syndrome
Interventions
BP1001 (varying dose), BP1001 (fixed dose), Dasatinib
Drug
Lead sponsor
Bio-Path Holdings, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 28, 2020 · Synced Oct 26, 2026, 10:18 PM EDT
Active, not recruiting Phase 2 Interventional

Venetoclax-Obinutuzumab +/- Acalabrutinib in R/R CLL

NCT04560322
View directory record Official record
Conditions
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Interventions
Venetoclax, Obinutuzumab, Acalabrutinib
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 26, 2026, 10:18 PM EDT