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ClinicalTrials.gov public records Last synced Oct 27, 2026, 8:17 PM EDT

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Showing 529–552 of 8,257 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Risk Clear all
Recruiting Phase 3 Interventional

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

NCT05712200
View directory record Official record
Conditions
Atrial Fibrillation (AF)
Interventions
Abelacimab, Placebo
Biological · Drug
Lead sponsor
Anthos Therapeutics, Inc.
Industry
Eligibility
65 Years and older
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
174
States / cities
Birmingham, Alabama • Mobile, Alabama • Gilbert, Arizona + 143 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 27, 2026, 8:17 PM EDT
Completed Phase 3 Interventional

Impact of Gastric Bypass Surgery on Risk of CVD in Type 2 Diabetes Mellitus

NCT00444392
View directory record Official record
Conditions
Obese Patients, Type 2 Diabetes Mellitus
Interventions
Calorie controlled diabetic diet for the control patients
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 60 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 21, 2016 · Synced Oct 27, 2026, 8:17 PM EDT
Recruiting Phase 2 Interventional

Ruxolitinib in Thrombocythemia and Polycythemia Vera

NCT04644211
View directory record Official record
Conditions
Essential Thrombocythemia, Polycythemia Vera
Interventions
Ruxolitinib
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2034
U.S. locations
4
States / cities
Boston, Massachusetts • Danvers, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 27, 2026, 8:17 PM EDT
Completed Not applicable Interventional

Improving Osteoporosis Care in High-Risk Home Health Patients

NCT00679198
View directory record Official record
Conditions
Patient Compliance, Communication, Osteoporosis, Fractures, Bone
Interventions
nurse-patient communication
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
Up to 95 Years
Enrollment
667 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Oct 27, 2026, 8:17 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Discovering New Genetic Markers in Adults and Children Who May Be At Risk for Hereditary Forms of Cancer

NCT03922893
View directory record Official record
Conditions
Cancer
Interventions
Family History Information, ORAGENE, Blood, Skin Biopsy
Other · Genetic
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Not listed
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2029
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 27, 2026, 8:17 PM EDT
Not yet recruiting Not applicable Interventional

Fitbit-Tracked Micromovement for Cardiometabolic Health in Rural Women

NCT07704749
View directory record Official record
Conditions
Cardiometabolic Risk Factors
Interventions
RISE-W Micro-Movement Program
Behavioral
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 27, 2026, 8:17 PM EDT
Active, not recruiting Phase 2 Interventional Results available

Nivolumab for the Reversal of Squamous Dysplasia in High Risk Current and Former Smokers

NCT03347838
View directory record Official record
Conditions
Bronchial Dysplasia, Tobacco Smoking, History of Non-Small Cell Lung Cancer, History of Head and Neck Cancer
Interventions
Nivolumab
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 80 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
2
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 27, 2026, 8:17 PM EDT
Completed Phase 2 Interventional

Pentostatin, Cyclophosphamide, and Rituximab in Treating Patients With Chronic Lymphocytic Leukemia or Other B-cell Cancers

NCT00003658
View directory record Official record
Conditions
Leukemia, Lymphoma
Interventions
filgrastim, rituximab, cyclophosphamide, pentostatin
Biological · Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2005
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 25, 2013 · Synced Oct 27, 2026, 8:17 PM EDT
Completed Phase 2 Interventional Results available

Genistein in Preventing Breast Cancer in Women at High Risk for Breast Cancer

NCT00290758
View directory record Official record
Conditions
Breast Cancer
Interventions
placebo, genistein, laboratory biomarker analysis
Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
25 Years and older · Female only
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 8, 2017 · Synced Oct 27, 2026, 8:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acceptability, Feasibility, and Preliminary Impact of a Web-based, HIV Prevention Toolkit With Cisgender Male Couples in Lima, Peru

NCT05873855
View directory record Official record
Conditions
HIV Infections, Hiv, Sexually Transmitted Infections (Not HIV or Hepatitis), Sexually Transmitted Diseases, Sexual Behavior, Risk Reduction
Interventions
Para ti, para mi, para nosotros (P3), Waitlist Control Para ti, para mi, para nosotros (P3)
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older · Male only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Oct 27, 2026, 8:17 PM EDT
Completed Phase 1Phase 2 Interventional

Clinical Evaluation of a Wireless Monitoring Device to Reduce Falls in the Elderly and Others at High Risk of Falling

NCT00249743
View directory record Official record
Conditions
Accidental Falls, Fractures, Injuries
Interventions
FallSaver (formerly called NOCwatch)
Device
Lead sponsor
NOCwatch International
Industry
Eligibility
0 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated May 29, 2006 · Synced Oct 27, 2026, 8:17 PM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

A First-in-human, 3-part Study of MRT-8102 in Healthy Participants and Participants at Cardiovascular Risk With Elevated CRP

NCT07119125
View directory record Official record
Conditions
Healthy Volunteers, Elevated CRP
Interventions
MRT-8102, Placebo
Drug
Lead sponsor
Monte Rosa Therapeutics, Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
4
States / cities
Miami, Florida • Lenexa, Kansas • Springfield, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 27, 2026, 8:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

HIV Prevention Toolkit for HIV-negative Male Couples

NCT02494817
View directory record Official record
Conditions
HIV
Interventions
Male Couples Agreement Project
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older · Male only
Enrollment
298 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Oct 27, 2026, 8:17 PM EDT
Completed No phase listed Observational Results available

Improving Screening and Therapy for Hispanic/Latinx at Risk for CKD

NCT05734989
View directory record Official record
Conditions
Type 2 Diabetes, Chronic Kidney Diseases
Interventions
BP, HbA1c, PCP Guidelines for Screening and Monitoring Hispanic/Latinx patients for CKD
Diagnostic Test · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 27, 2026, 8:17 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Sleep Effectiveness and Insulin and Glucose Homeostasis

NCT01887691
View directory record Official record
Conditions
Diabetes, Prediabetic, Prediabetes, Glucose Intolerance
Interventions
eszopiclone
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 64 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 19, 2019 · Synced Oct 27, 2026, 8:17 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Blood Samples From Older Patients at High Risk of Developing Prostate Cancer and From Healthy Male Participants

NCT00898274
View directory record Official record
Conditions
Precancerous Condition, Prostate Cancer
Interventions
immunoenzyme technique, laboratory biomarker analysis
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
45 Years to 65 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
3
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 9, 2016 · Synced Oct 27, 2026, 8:17 PM EDT
Completed Phase 3 Interventional Results available

Evaluating How the Treatments in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Study Affect Diabetic Retinopathy (The ACCORD Eye Study)

NCT00542178
View directory record Official record
Conditions
Diabetic Retinopathy
Interventions
Hypoglycemic Agents, Standard glycemia control, Intensive BP treatment, Standard BP control, Fenofibrate, Simvastatin, Placebo
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
40 Years to 79 Years
Enrollment
3,472 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
6
States / cities
Minneapolis, Minnesota • New York, New York • Winston-Salem, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2018 · Synced Oct 27, 2026, 8:17 PM EDT
Suspended Not applicable Interventional

From Hardship to Hope: A Peer-led Intervention to Reduce Financial Hardship and Suicide Risk

NCT04840134
View directory record Official record
Conditions
Suicide, Suicide Ideation, Suicidal Behavior, Hope, Financial Stress
Interventions
From Hardship to Hope: A Peer-led intervention to reduce financial hardship and suicide risk, Enhanced Treatment as Usual (eTAU)
Behavioral · Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 64 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 27, 2026, 8:17 PM EDT
Completed No phase listed Observational

Risk Factors and Potential Causes of Eustachian Tube Dysfunction in Adults

NCT01251432
View directory record Official record
Conditions
Eustachian Tube Dysfunction, Chronic Otitis Media
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 4, 2016 · Synced Oct 27, 2026, 8:17 PM EDT
Completed Phase 3 Interventional Results available

Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC)

NCT05136898
View directory record Official record
Conditions
Bladder Cancer, Urothelial Carcinoma, Urothelial Carcinoma Bladder
Interventions
UGN-102
Drug
Lead sponsor
UroGen Pharma Ltd.
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
5
States / cities
Homewood, Alabama • Indianapolis, Indiana • Greensboro, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 27, 2026, 8:17 PM EDT
Completed Phase 1 Interventional

Nilotinib With Radiation for High Risk Chordoma

NCT01407198
View directory record Official record
Conditions
Chordoma
Interventions
Nilotinib, Radiation therapy
Drug · Radiation
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 27, 2026, 8:17 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Healing Hearts: A Mindfulness App for Parents Navigating Divorce or Separation

NCT07871916
View directory record Official record
Conditions
Mental Health, Parenting / Maternal Behavior, Parenting Anxiety, Parenting Behavior, Stress, Psychological Distress, Depression and Anxiety Symptoms, Internalizing Problems, Externalizing Problems
Interventions
Healing Hearts, electronic New Beginnings Program, Curated internet resources
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 27, 2026, 8:17 PM EDT
Completed No phase listed Observational

Questionnaire and Fall Risk Assessment

NCT00836238
View directory record Official record
Conditions
Prostate Cancer
Interventions
Interview, Physical Function Tests
Behavioral · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
65 Years and older · Male only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 1, 2012 · Synced Oct 27, 2026, 8:17 PM EDT
Not listed Not applicable Interventional

Fall Risk Reduction in Multiple Sclerosis (FIRMS)

NCT02314585
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Exercise, Education
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 64 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 26, 2015 · Synced Oct 27, 2026, 8:17 PM EDT