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ClinicalTrials.gov public records Last synced Oct 31, 2026, 10:16 AM EDT

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Showing 1009–1032 of 8,261 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Risk Clear all
Active, not recruiting Phase 3 Interventional Results available

A Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Participants Who Require Red Blood Cell Transfusions and Are ESA Naïve

NCT03682536
View directory record Official record
Conditions
Myelodysplastic Syndromes
Interventions
Luspatercept, Epoetin alfa
Drug
Lead sponsor
Celgene
Industry
Eligibility
18 Years and older
Enrollment
363 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
25
States / cities
Berkeley, California • San Diego, California • Whittier, California + 22 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Oct 31, 2026, 10:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Public Health Program to Reduce Risk of Antepartum Depression

NCT02144844
View directory record Official record
Conditions
Depression
Interventions
Insight-Plus Cognitive Behavioral Intervention
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years and older · Female only
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
2
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated May 22, 2014 · Synced Oct 31, 2026, 10:16 AM EDT
Not yet recruiting No phase listed Observational

Improving Implementation of Guideline-Recommended LDL-C Management in High-Risk Cardiovascular Patients

NCT07883564
View directory record Official record
Conditions
ASCVD
Interventions
Not listed
Lead sponsor
Cardiology Consultants of Philadelphia
Other
Eligibility
18 Years and older
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
5
States / cities
Clearwater, Florida • Jacksonville, Florida • Houma, Louisiana + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 31, 2026, 10:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Risk After an Adverse Pregnancy Outcome

NCT01182363
View directory record Official record
Conditions
Maternal Depression
Interventions
Project Solve Education
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
Female only
Enrollment
188 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
4
States / cities
Boston, Massachusetts • Natick, Massachusetts • Quincy, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2014 · Synced Oct 31, 2026, 10:16 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Inflammation, Viral Replication, and Atherosclerosis in Treated HIV Infection

NCT01519141
View directory record Official record
Conditions
Atherosclerosis
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
579 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 10, 2021 · Synced Oct 31, 2026, 10:16 AM EDT
Completed Not applicable Interventional Results available

Heart Health Buddies: Peer Support to Decrease CVD Risk

NCT03646656
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
reciprocal peer support and non reciprocal coach support
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
35 Years to 64 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 31, 2026, 10:16 AM EDT
Completed Phase 2 Interventional Results available

Lenalidomide With or Without Rituximab After Standard Chemotherapy in Treating Patients With Diffuse Large B-Cell Non-Hodgkin Lymphoma

NCT00765245
View directory record Official record
Conditions
Lymphoma
Interventions
Lenalidomide, Rituximab
Drug
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
4
States / cities
Chapel Hill, North Carolina • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 11, 2016 · Synced Oct 31, 2026, 10:16 AM EDT
Withdrawn No phase listed Observational

CA-125 in Screening Patients at High Risk for Ovarian Cancer

NCT00080639
View directory record Official record
Conditions
Ovarian Cancer
Interventions
physiologic testing, study of high risk factors
Other · Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
30 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 5, 2013 · Synced Oct 31, 2026, 10:16 AM EDT
Completed Phase 3 Interventional

Surgery in Treating Children With Neuroblastoma

NCT00003119
View directory record Official record
Conditions
Neuroblastoma
Interventions
filgrastim, sargramostim, carboplatin, cyclophosphamide, doxorubicin hydrochloride, etoposide, adjuvant therapy, conventional surgery, radiation therapy
Biological · Drug · Procedure + 1 more
Lead sponsor
Children's Oncology Group
Network
Eligibility
Up to 21 Years
Enrollment
968 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2006
U.S. locations
207
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 150 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Oct 31, 2026, 10:16 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Understanding Physician Signout Risk Perception

NCT02648828
View directory record Official record
Conditions
Physician Judgment
Interventions
Clinical deterioration
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 28, 2017 · Synced Oct 31, 2026, 10:16 AM EDT
Recruiting No phase listed Observational

Study to Understand the Genetic Risk of Developing an Immune Response After Blood Transfusions Among Individuals With Sickle Cell Disease

NCT06944067
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
2 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 31, 2026, 10:16 AM EDT
Terminated Not applicable Interventional

Farming for Life - Health Impact of Organic Vegetable Prescriptions for Adults Living With or at Risk of Type 2 Diabetes

NCT03940300
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Food Supply, Poverty, Minority Health, Obesity
Interventions
Fresh organic vegetables
Dietary Supplement
Lead sponsor
Sansum Diabetes Research Institute
Other
Eligibility
18 Years and older
Enrollment
303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2022 · Synced Oct 31, 2026, 10:16 AM EDT
Terminated Phase 3 Interventional Results available

Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery

NCT01533207
View directory record Official record
Conditions
Stage I Uterine Sarcoma AJCC v7, Uterine Corpus Leiomyosarcoma
Interventions
Clinical Observation, Docetaxel, Doxorubicin Hydrochloride, Filgrastim, Gemcitabine Hydrochloride, Pegfilgrastim
Other · Drug · Biological
Lead sponsor
Gynecologic Oncology Group
Network
Eligibility
18 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
608
States / cities
Huntsville, Alabama • Anchorage, Alaska • Fairbanks, Alaska + 374 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2020 · Synced Oct 31, 2026, 10:16 AM EDT
Recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

NCT05552157
View directory record Official record
Conditions
Alzheimers Disease, Dementia, Alzheimers Disease, Familial
Interventions
Remternetug (SC), Matching Placebo (Remternetug)
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2034
U.S. locations
13
States / cities
Birmingham, Alabama • La Jolla, California • Los Angeles, California + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 31, 2026, 10:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Facilitating Participation in a Prostate Cancer Risk Assessment Program

NCT02126319
View directory record Official record
Conditions
Prostate Cancer
Interventions
Cognitive Affective preparation, General Health Education
Behavioral
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
34 Years to 69 Years · Male only
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2002
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2017 · Synced Oct 31, 2026, 10:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treating Pre-School Children at Risk for Overweight in the Primary Care Setting

NCT01029834
View directory record Official record
Conditions
Overweight
Interventions
family based lifestyle and behavioral counseling, counseling focused on the child
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
2 Years to 6 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
2
States / cities
Buffalo, New York • Williamsville, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2023 · Synced Oct 31, 2026, 10:16 AM EDT
Not yet recruiting Not applicable Interventional

Evaluation of Community Health Worker Support to Help People With Serious Mental Illness to Quit Smoking

NCT07789132
View directory record Official record
Conditions
Nicotine Dependance, Serious Mental Illness, Smoking (Tobacco) Addiction, Tobacco Cessation, Community Health Workers, Cardiovascular (CV) Risk, Tobacco Use Disorder
Interventions
Integrated CHW Support intervention, Enhanced usual care (EUC)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
937 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 31, 2026, 10:16 AM EDT
Terminated Phase 2 Interventional

LIFE-Lung Bronchoscopy in Patients at Risk for Developing Lung Cancer

NCT00260598
View directory record Official record
Conditions
Non-Small-Cell Lung Carcinoma, Head and Neck Squamous Cell Cancer, Pulmonary Disease, Chronic Obstructive
Interventions
LIFE Bronchoscopy
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 85 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 13, 2018 · Synced Oct 31, 2026, 10:16 AM EDT
Completed No phase listed Observational

Infant Transition From Car Bed to Car Safety Seat

NCT00953316
View directory record Official record
Conditions
Car Seat Transition for At-risk Infants
Interventions
Measure infant's jaw, record all information about car seat testing, and administer questionnaires.
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Day to 1 Year
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 11, 2017 · Synced Oct 31, 2026, 10:16 AM EDT
Completed Phase 2 Interventional

Letrozole in Preventing Breast Cancer in Postmenopausal Women Who Are at Increased Risk for Breast Cancer Due to High Breast Density

NCT00238316
View directory record Official record
Conditions
Breast Cancer
Interventions
letrozole, Placebo
Drug · Other
Lead sponsor
NCIC Clinical Trials Group
Network
Eligibility
Up to 120 Years · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2009
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Oct 31, 2026, 10:16 AM EDT
Completed No phase listed Observational

Vascular Reactivity in Metabolic Syndrome and Diabetic Patients Using Diffuse Optical Spectroscopy

NCT00793481
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Diffuse Optical Spectroscopy
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
45 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Oct 31, 2026, 10:16 AM EDT
Terminated Phase 2 Interventional Results available

Clinical Study of Noni Extract in Men With Very Low Risk or Low Risk Prostate Cancer

NCT02648919
View directory record Official record
Conditions
Prostate Cancer
Interventions
Noni extract
Drug
Lead sponsor
University of Hawaii
Other
Eligibility
55 Years and older · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Nov 26, 2021 · Synced Oct 31, 2026, 10:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Balance and Mobility

NCT02374463
View directory record Official record
Conditions
Postural Balance, Accidental Falls, Mobility Limitation
Interventions
MMBI, Tai Chi
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 27, 2020 · Synced Oct 31, 2026, 10:16 AM EDT
Recruiting Phase 2 Interventional

MRI-based Focal Intraprostatic Simultaneous Integrated Boost (SIB) Intensification With De-escalated Adaptive-risk SBRT for Patients With Low to Intermediate Risk Prostate Cancer

NCT07644598
View directory record Official record
Conditions
Prostate Cancer, Localized Prostate Carcinoma
Interventions
Microboost SBRT, Whole gland de-escalation 30 Gy, Whole gland de-escalation 35 Gy
Radiation
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older · Male only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2035
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 31, 2026, 10:16 AM EDT