Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Jul 21, 2026, 4:01 PM EDT

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Showing 1–24 of 46 matching trials from the live ClinicalTrials.gov search.
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Conditions
Rumination Disorder
Interventions
CBT-RD
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
10 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts • Philadelphia, Pennsylvania
Conditions
Insomnia, Depression
Interventions
Perinatal Understanding of Mindful Awareness for Sleep (PUMAS), Treatment-as-usual (TAU)
Behavioral · Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Novi, Michigan
Completed Phase 3 Interventional Accepts healthy volunteers

Baclofen for Children With Rumination Syndrome

NCT05975684
Conditions
Rumination Syndrome
Interventions
Baclofen, Placebo
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
4 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Recruiting Not applicable Interventional

Suicide Specific Rumination in Veterans

NCT06481033
Conditions
Depression, Suicide, Mood Disorders
Interventions
Real Time fMRI Neurofeedback
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
Interventions
Emotion Regulation Therapy - Attention Regulation (AR-ERT), Supportive Psychotherapy (SPT)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Rumination
Interventions
Mindfulness (Headspace) App, Active Control Condition ("Recharge" condition delivered in Headspace app)
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
13 Years to 18 Years
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Belmont, Massachusetts
Conditions
Prostate Cancer
Interventions
Health promotion
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
4
States / cities
Chicago, Illinois • Evanston, Illinois • Ann Arbor, Michigan + 1 more
Conditions
Stress, Psychological, Anxiety, Depression, Rumination, Emotional Regulation, Mindfulness, Self-Compassion, Emotional Distress
Interventions
Mindfulness meditation
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Recruiting Not applicable Interventional

Meditative Neurofeedback for Depression

NCT06675240
Conditions
Depression - Major Depressive Disorder, Depression Disorders
Interventions
MediNF
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
La Jolla, California
Conditions
Rumination, Worry, Self-Criticism, Anxiety, Depression, Distress, Emotional
Interventions
Emotion Regulation Therapy via Telehealth
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Insomnia, Primary, Major Depressive Disorder, Rumination
Interventions
digital Cognitive Behavioral Therapy for Insomnia, face-to-face Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene Education Control
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
1,237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Novi, Michigan
Conditions
Schizophrenia, Depressive Disorder, Major
Interventions
Electroencephalography (EEG) and Magnetic Resonance Imaging (MRI)
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
San Francisco, California
Conditions
Major Depressive Disorder
Interventions
Siemens 7T MRI, Sham Neurofeedback
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Rumination, Depressive Symptoms, Blood Pressure
Interventions
Rumination-Focused Cognitive Behavior Therapy
Behavioral
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Louisville, Kentucky
Conditions
Major Depressive Disorder, Mood Disorders
Interventions
Rumination-Focused CBT, Relaxation-based Therapy
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
14 Years to 17 Years
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
3
States / cities
Columbus, Ohio • Salt Lake City, Utah
Conditions
Rumination Disorder
Interventions
CBT-RD
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
10 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Effect of Environment on the Central and Peripheral Nervous System

NCT06778356
Conditions
Rumination
Interventions
Built environment, Natural environment
Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Distress, Emotional, Emotional Dysfunction, Anxiety, Depression
Interventions
Online, Self-Directed Attention Skills Training with Coaching Support, Online, Self-Directed Attention & Reflective Thought Skills Training with Coaching Support, Online, Self-Directed Health & Wellness Education Training with Coaching Support
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Conditions
Depression
Interventions
MBCT, PRT-PsyEd
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Neural Predictors of Social Emotion Regulation Training

NCT03487081
Conditions
Emotions, Rumination
Interventions
Social regulation, Self regulation
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 35 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Conditions
Depression, Treatment Resistant
Interventions
Transcranial magnetic stimulation
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Treatment-Resistant Major Depressive Disorder
Interventions
Psilocybin
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Charlestown, Massachusetts
Conditions
Rumination, Worry, Self-Criticism, Anxiety, Depression, Distress, Emotional
Interventions
Emotion Regulation Therapy via Telehealth
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Conditions
Barrett Esophagus, Anorexia Nervosa, Binge Eating/Purging Type, Rumination, Vomiting, Eating Disorders, Esophageal Adenocarcinoma
Interventions
EsoGuard
Device
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Denver, Colorado