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Showing 25–46 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Rumination Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness, Emotional Well-being, and Sleep Quality

NCT00887614
View directory record Official record
Conditions
Stress, Psychological, Sleep
Interventions
Mindfulness-Based Stress Reduction (MBSR)
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
372 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 3, 2011 · Synced Jul 21, 2026, 6:07 PM EDT
Not yet recruiting Not applicable Interventional

Calming Minds Study

NCT07577401
View directory record Official record
Conditions
Anxiety, Anxiety Depression, Worry, Depression, Rumination - Thoughts
Interventions
Be Specific, Be Kind, Be Present, Break Habit, Psychoeducation
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Imperial, California
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional Results available

Testing a Digital Intervention for Adolescents

NCT04567888
View directory record Official record
Conditions
Rumination, Stress, Psychological
Interventions
Happify Teens
Behavioral
Lead sponsor
Happify Inc.
Industry
Eligibility
13 Years to 17 Years
Enrollment
353 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 14, 2024 · Synced Jul 21, 2026, 6:07 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

My Life and My Experiences Project

NCT06821178
View directory record Official record
Conditions
Stress and Memory in Adolescence
Interventions
Acute stress manipulation
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
12 Years to 18 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional

A Treatment for Depression Via a Gamified Mobile Phone Application Based on a New Cognitive Model

NCT05685758
View directory record Official record
Conditions
Depression, Depressive Disorder, Clinical Depression, Major Depressive Disorder
Interventions
FTP-based therapeutic mobile-app
Other
Lead sponsor
Hedonia Ltd
Industry
Eligibility
20 Years to 50 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Jul 21, 2026, 6:07 PM EDT
Not yet recruiting Not applicable Interventional

Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis

NCT07503093
View directory record Official record
Conditions
Psychosis, Anxiety, Depression, Rumination
Interventions
Smartphone-based Mindfulness Exercise, Smartphone-based Psychoeducation, Neutral Control Message
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional

Study to Identify if OVR Health's VR-Kit is Safe to Use and Helps to Improve Focus, Attention and Reduce Worry & Rumination.

NCT05291429
View directory record Official record
Conditions
Anxiety, Depression, Anxiety
Interventions
OVR Health's VR experience
Device
Lead sponsor
Oxford VR
Industry
Eligibility
18 Years to 79 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Jul 21, 2026, 6:07 PM EDT
Recruiting Not applicable Interventional

Mindfulness-Based fMRI Neurofeedback for Depression

NCT05617495
View directory record Official record
Conditions
Depression in Adolescence, Rumination
Interventions
Mindfulness + fMRI Neurofeedback
Other
Lead sponsor
Columbia University
Other
Eligibility
13 Years to 18 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Recruiting Not applicable Interventional

Decoding and Modulating Affective Brain States

NCT05437705
View directory record Official record
Conditions
Rumination, Major Depressive Disorder, Anxiety
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional

Intervention for Intrusive Negative Thinking

NCT02394704
View directory record Official record
Conditions
Intrusive Negative Thinking
Interventions
Sensory attention training
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 6, 2021 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional

Emotion Regulation Therapy for Clinical Worry and Rumination

NCT04060940
View directory record Official record
Conditions
Anxiety Disorders and Symptoms, Depression, Anxiety, Generalized Anxiety Disorder, Emotional Dysfunction
Interventions
Emotion Regulation Therapy: 8-session version, Emotion Regulation Therapy: 16-session version
Behavioral
Lead sponsor
Douglas Mennin
Other
Eligibility
18 Years to 29 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Phase 3 Interventional

Comparison of Diaphragmatic Breathing and Muscle Relaxation for Rumination

NCT01576302
View directory record Official record
Conditions
Rumination
Interventions
Diaphragmatic breathing, Muscle relaxation
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 9, 2014 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional

Brief Cognitive Behavioral Therapy to Treat Itch Rumination "Itch CBT" in Eczema

NCT04486742
View directory record Official record
Conditions
Atopic Dermatitis
Interventions
Itch CBT
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
8 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 8, 2023 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional

Insomnia and Rumination in Late Pregnancy and the Risk for Postpartum Depression

NCT03596879
View directory record Official record
Conditions
Insomnia, Post Partum Depression
Interventions
dCBTI, Sleep Education
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 4, 2019 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional Results available

Reduce Emotional Symptoms of Insomnia With SleepTreatment

NCT03724305
View directory record Official record
Conditions
Insomnia, Rumination
Interventions
Mindfulness-Based Therapy for Insomnia
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional

Neurobehavioral Affective Control Training

NCT06226467
View directory record Official record
Conditions
Emotional Distress, Impulsive Behavior, Mood Lability, Mood Instability, Rumination, Psychopathology, Affective Symptoms
Interventions
Neurobehavioral Affective Control Training
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional

Evaluating a Mobile Phone Intervention

NCT04554706
View directory record Official record
Conditions
Depression, Rumination - Thoughts
Interventions
Mobile-phone delivered Treatment for Excessive Rumination
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brief App-based Mood Monitoring and Mindfulness Intervention for First-year College Students

NCT06348277
View directory record Official record
Conditions
Depression, Anxiety, Self-Injurious Behavior
Interventions
Mindfulness plus mood monitoring, Mood monitoring
Behavioral
Lead sponsor
Lawrence University
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Appleton, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 3, 2024 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adolescent Mindfulness Mobile App Study (RCT)

NCT03900416
View directory record Official record
Conditions
Rumination, Depression, Anxiety, Self-Injurious Behavior
Interventions
Mindfulness App
Behavioral
Lead sponsor
Lawrence University
Other
Eligibility
12 Years to 15 Years
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Appleton, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 7, 2021 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional

Cognitive Process-based Real-time fMRI Neurofeedback in MDD and Rumination

NCT04941066
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Active neurofeedback, Sham neurofeedback
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 17, 2023 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts"

NCT03414619
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
Interventions
Cognitive Control Tasks and Script Driven Imagery
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Jul 21, 2026, 6:07 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Self Focus in Bipolar Disorder: A Functional Magnetic Resonance Imaging (fMRI) Study

NCT02253225
View directory record Official record
Conditions
Bipolar Disorder, Major Depression, Rumination
Interventions
Functional Magnetic Resonance Imaging (fMRI)
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Jul 21, 2026, 6:07 PM EDT