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Showing 25–46 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Rumination Clear all
Not yet recruiting Not applicable Interventional

Calming Minds Study

NCT07577401
View directory record Official record
Conditions
Anxiety, Anxiety Depression, Worry, Depression, Rumination - Thoughts
Interventions
Be Specific, Be Kind, Be Present, Break Habit, Psychoeducation
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Imperial, California
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 7, 2026, 2:39 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents

NCT04697966
View directory record Official record
Conditions
Rumination
Interventions
Mindfulness (Headspace) App, Active Control Condition ("Recharge" condition delivered in Headspace app)
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
13 Years to 18 Years
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 7, 2026, 2:39 PM EDT
Completed Not applicable Interventional

Neurobehavioral Affective Control Training

NCT06226467
View directory record Official record
Conditions
Emotional Distress, Impulsive Behavior, Mood Lability, Mood Instability, Rumination, Psychopathology, Affective Symptoms
Interventions
Neurobehavioral Affective Control Training
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 7, 2026, 2:39 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Effect of Environment on the Central and Peripheral Nervous System

NCT06778356
View directory record Official record
Conditions
Rumination
Interventions
Built environment, Natural environment
Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Sep 7, 2026, 2:39 PM EDT
Completed Not applicable Interventional

App-Based Mindfulness Meditation for People of Color Who Experience Race-Related Stress

NCT05027113
View directory record Official record
Conditions
Stress, Psychological, Anxiety, Depression, Rumination, Emotional Regulation, Mindfulness, Self-Compassion, Emotional Distress
Interventions
Mindfulness meditation
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Sep 7, 2026, 2:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adolescent Mindfulness Mobile App Study (RCT)

NCT03900416
View directory record Official record
Conditions
Rumination, Depression, Anxiety, Self-Injurious Behavior
Interventions
Mindfulness App
Behavioral
Lead sponsor
Lawrence University
Other
Eligibility
12 Years to 15 Years
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Appleton, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 7, 2021 · Synced Sep 7, 2026, 2:39 PM EDT
Completed Not applicable Interventional

Emotion Regulation Therapy for Clinical Worry and Rumination

NCT04060940
View directory record Official record
Conditions
Anxiety Disorders and Symptoms, Depression, Anxiety, Generalized Anxiety Disorder, Emotional Dysfunction
Interventions
Emotion Regulation Therapy: 8-session version, Emotion Regulation Therapy: 16-session version
Behavioral
Lead sponsor
Douglas Mennin
Other
Eligibility
18 Years to 29 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Sep 7, 2026, 2:39 PM EDT
Completed Not applicable Interventional Results available

Reduce Emotional Symptoms of Insomnia With SleepTreatment

NCT03724305
View directory record Official record
Conditions
Insomnia, Rumination
Interventions
Mindfulness-Based Therapy for Insomnia
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Sep 7, 2026, 2:39 PM EDT
Recruiting Not applicable Interventional

Meditative Neurofeedback for Depression

NCT06675240
View directory record Official record
Conditions
Depression - Major Depressive Disorder, Depression Disorders
Interventions
MediNF
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 7, 2026, 2:39 PM EDT
Completed Not applicable Interventional

A Pilot Study of Cognitive-Behavioral Therapy for Rumination Disorder (CBT-RD)

NCT03062696
View directory record Official record
Conditions
Rumination Disorder
Interventions
CBT-RD
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
10 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 16, 2019 · Synced Sep 7, 2026, 2:39 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Rescuing the Ruminating Brain: Identifying Biomarkers of Rumination and Mindfulness Through Concurrent EEG and Functional Magnetic Resonance Imaging (fMRI) Studies of Schizophrenia and Depression

NCT03758495
View directory record Official record
Conditions
Schizophrenia, Depressive Disorder, Major
Interventions
Electroencephalography (EEG) and Magnetic Resonance Imaging (MRI)
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2019 · Synced Sep 7, 2026, 2:39 PM EDT
Recruiting Phase 2 Interventional

Sleep to Reduce Incident Depression Effectively in Peripartum

NCT06430333
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Perinatal Understanding of Mindful Awareness for Sleep (PUMAS), Treatment-as-usual (TAU)
Behavioral · Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 7, 2026, 2:39 PM EDT
Completed Not applicable Interventional

Cognitive Process-based Real-time fMRI Neurofeedback in MDD and Rumination

NCT04941066
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Active neurofeedback, Sham neurofeedback
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 17, 2023 · Synced Sep 7, 2026, 2:39 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Network Neurofeedback Using 7-Tesla MRI to Reduce Rumination Levels in Depression

NCT05933148
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Siemens 7T MRI, Sham Neurofeedback
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 7, 2026, 2:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing the Effects of Active Surveillance Stress, Uncertainty and Rumination Thru Engagement in Mindfulness Education

NCT02871752
View directory record Official record
Conditions
Prostate Cancer
Interventions
Health promotion
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
4
States / cities
Chicago, Illinois • Evanston, Illinois • Ann Arbor, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2023 · Synced Sep 7, 2026, 2:39 PM EDT
Completed Not applicable Interventional

Suicide Specific Rumination in Veterans

NCT06481033
View directory record Official record
Conditions
Depression, Suicide, Mood Disorders
Interventions
Real Time fMRI Neurofeedback
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 7, 2026, 2:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts"

NCT03414619
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
Interventions
Cognitive Control Tasks and Script Driven Imagery
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Sep 7, 2026, 2:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Can Rumination-Focused Cognitive Behavioral Therapy Reduce the Risk of Cardio-vascular Disease?

NCT05980130
View directory record Official record
Conditions
Rumination, Depressive Symptoms, Blood Pressure
Interventions
Rumination-Focused Cognitive Behavior Therapy
Behavioral
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Sep 7, 2026, 2:39 PM EDT
Completed Not applicable Interventional

Insomnia and Rumination in Late Pregnancy and the Risk for Postpartum Depression

NCT03596879
View directory record Official record
Conditions
Insomnia, Post Partum Depression
Interventions
dCBTI, Sleep Education
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 4, 2019 · Synced Sep 7, 2026, 2:39 PM EDT
Completed Not applicable Interventional Results available

Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts

NCT04225624
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
Interventions
Emotion Regulation Therapy - Attention Regulation (AR-ERT), Supportive Psychotherapy (SPT)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 7, 2026, 2:39 PM EDT
Not yet recruiting Not applicable Interventional

Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis

NCT07503093
View directory record Official record
Conditions
Psychosis, Anxiety, Depression, Rumination
Interventions
Smartphone-based Mindfulness Exercise, Smartphone-based Psychoeducation, Neutral Control Message
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 7, 2026, 2:39 PM EDT
Completed Not applicable Interventional

Evaluating a Mobile Phone Intervention

NCT04554706
View directory record Official record
Conditions
Depression, Rumination - Thoughts
Interventions
Mobile-phone delivered Treatment for Excessive Rumination
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Sep 7, 2026, 2:39 PM EDT