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Showing 25–48 of 86 matching trials from the live ClinicalTrials.gov search.
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Different Ingestion Doses of Celastrol on Human Sperm Motility

NCT05413226
Conditions
Safety Issues
Interventions
Celastrol
Dietary Supplement
Lead sponsor
Legend Labz, Inc.
Industry
Eligibility
18 Years to 40 Years · Male only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Completed Phase 1 Interventional Accepts healthy volunteers

Choline Dehydrogenase and Sperm Function: Effects of Betaine

NCT02122211
Conditions
Men Carrying 2 Minor Alleles for Choline Dehydrogenase rs12676, Male Infertility
Interventions
Betaine supplement
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Kannapolis, North Carolina
Conditions
Infertility
Interventions
ICSI
Other
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
7 participants
Timeline
2018 – 2021
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Conditions
Human Volunteer
Interventions
minocycline extended release, Placebo
Drug
Lead sponsor
Medicis Pharmaceutical Corporation
Industry
Eligibility
18 Years and older · Male only
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
10
States / cities
Tarzana, California • Minneapolis, Minnesota • Lawrenceville, New Jersey + 7 more
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Impact of Escitalopram on Sperm DNA Fragmentation

NCT03527043
Conditions
Sperm DNA Fragmentation, Infertility, Male
Interventions
Escitalopram, Placebo
Drug · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
New York, New York
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Evaluation Of Sperm Production With Healthy Male Volunteers Receiving Lyrica Or Placebo

NCT00631696
Conditions
Healthy
Interventions
Pregabalin, Placebo
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
18 Years to 55 Years · Male only
Enrollment
222 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
13
States / cities
Mobile, Alabama • Phoenix, Arizona • Tarzana, California + 9 more
Conditions
Brain and Central Nervous System Tumors, Chemotherapeutic Agent Toxicity, Infertility
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Erectile Dysfunction
Interventions
tadalafil, placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
45 Years and older · Male only
Enrollment
282 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
1
States / cities
Bothell, Washington
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Ramipril for the Treatment of Oligospermia

NCT01856361
Conditions
Oligospermia, Teratospermia, Asthenozoospermia, Male Infertility
Interventions
Ramipril, Placebo
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Conditions
Infertility
Interventions
Artificial Intelligence assisted sperm selection
Other
Lead sponsor
Ovation Fertility
Other
Eligibility
Not listed
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Las Vegas, Nevada • Austin, Texas
Conditions
Oligozoospermia, Asthenozoospermia, Teratozoospermia, Fertility
Interventions
Walnuts, OTC multivitamin
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years and older · Male only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
2
States / cities
Los Angeles, California
Conditions
Male Contraception, Semen Volume, Sperm Motility
Interventions
NLS-133, Placebo, Active Comparator #1
Drug
Lead sponsor
Next Life Sciences
Industry
Eligibility
18 Years to 55 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Fertilization
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of New Semen Collection & Transportation Kit

NCT04536545
Conditions
Sperm Parameters in Fertile and Infertile Men
Interventions
Not listed
Lead sponsor
Turtle Health, Inc.
Industry
Eligibility
Male only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Observe Effect of Antioxidant on Sperm DNA Fragmention
Interventions
Natural Antioxidant supplement
Dietary Supplement
Lead sponsor
Colorado Center for Reproductive Medicine
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
54 participants
Timeline
2018 – 2022
U.S. locations
1
States / cities
Lone Tree, Colorado
Conditions
Infertility, Infertility, Male
Interventions
Laser-assisted intracytoplasmic sperm injection
Procedure
Lead sponsor
Shady Grove Fertility Reproductive Science Center
Other
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
1
States / cities
Rockville, Maryland
Conditions
Oligospermia, Azoospermia, Nonobstructive, Infertility
Interventions
isotretinoin, Human chorionic gonadotrophin (hCG)
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 50 Years · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Conditions
Secondary Hypogonadism
Interventions
Androxal 12.5 mg or 25 mg, AndroGel 1.62%, Placebo Capsules, Placebo Gel
Drug
Lead sponsor
Repros Therapeutics Inc.
Industry
Eligibility
18 Years to 60 Years · Male only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
8
States / cities
Jacksonville, Florida • Albany, New York • Raleigh, North Carolina + 5 more
Conditions
Infertility
Interventions
SpermComet assay
Other
Lead sponsor
Bruce Shapiro M.D.
Industry
Eligibility
18 Years and older · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Las Vegas, Nevada
Conditions
HIV-1, Fertility, Infertility
Interventions
Sperm Washing with Intrauterine Insemination (IUI)
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Cancer
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
13 Years to 21 Years · Male only
Enrollment
282 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
8
States / cities
Duarte, California • Los Angeles, California • Atlanta, Georgia + 5 more
Conditions
Erectile Dysfunction
Interventions
Levitra (Vardenafil, BAY38-9456), Sildenafil, Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
25 Years to 64 Years · Male only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
18
States / cities
Phoenix, Arizona • Tempe, Arizona • Beverly Hills, California + 15 more
Conditions
Male Infertility
Interventions
Not listed
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
35 Years to 40 Years
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Basking Ridge, New Jersey • Allentown, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

FemaSeed LOCAL Artificial Insemination Trial

NCT04968847
Conditions
Infertility, Male Factor
Interventions
FemaSeed Localized Directional Insemination
Device
Lead sponsor
Femasys Inc.
Industry
Eligibility
19 Years to 40 Years · Female only
Enrollment
314 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
18
States / cities
Mobile, Alabama • Newark, Delaware • Clearwater, Florida + 13 more