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Conditions: Epilepsy
Interventions: oxygen; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 70 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Unipolar Depression
Interventions: MRI, MagPro TMS stimulator and coil, Thymatron (R) System IV paired with 4X1 HDECT; Device
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 22 Years to 70 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Covid19, SARS-CoV2 Infection
Interventions: Focal Mask; Device
Lead sponsor: Georgia Institute of Technology; Other
Eligibility: 18 Years and older
Enrollment: 201 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Cardiovascular Diseases, Cardiovascular Diseases Risk, Cardiac Conduction System Disease, Bundle/Fascicular Abnormalities, His-Purkinje Disease, Arrhythmias, Cardiac, Rhythm Phenotypes, Myocardial Ischemia, Syncope, Syncope Recurrent, Syncope and Collapse, Seizure Disorder, Sleep Apnea Syndrome, Obstructive, Decision Support Systems, Clinical, Heart Failure - NYHA II - IV, Heart Failure (for Example, Fluid Overload), HRV, Cardiopulmonary, Sudden Cardiac Arrest, Cardiac Arrest (CA), Ventricular Arrhythmias and Cardiac Arrest, Ventricular Fibrillation, QT Dispersion, Atrial Cardiomyopathy
Interventions: COR Wearable ECG Monitoring, Cor360 Clinician-Facing Decision-Aid Reporting; Device · Other
Lead sponsor: Peerbridge Health, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 2
States / cities: Pasadena, California • Nashville, Tennessee

Conditions: Seizures
Interventions: Midazolam; Drug
Lead sponsor: U.S. Army Office of the Surgeon General; Federal
Eligibility: 18 Years to 54 Years
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Tuberous Sclerosis Complex-associated Refractory Seizures
Interventions: RAD001, Placebo, Antiepileptic drug (1 to 3 only), open label RAD001 (only used for post-extension phase); Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 2 Years to 65 Years
Enrollment: 366 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 22
States / cities: Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 18 more

Conditions: Hearing Loss, Ear Diseases, Hearing Disorders, Otolaryngological Disease
Interventions: Pinna-located microphone, Pinna-simulated microphone algorithm; Device
Lead sponsor: Advanced Bionics; Industry
Eligibility: 8 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Valencia, California

Conditions: Partial Onset Seizures, Secondarily Generalized Seizures, Primary Generalized Tonic-Clonic Seizures
Interventions: Perampanel; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 4 Years and older
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 24
States / cities: Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 20 more

Conditions: Epilepsy
Interventions: Dietary management of seizures; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Epilepsy, Generalized, Absence Epilepsy, Absence Seizures, Seizures, Seizure Disorder
Interventions: Eye movement analysis; Diagnostic Test
Lead sponsor: Rachel Kuperman; Industry
Eligibility: 4 Years to 100 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 5
States / cities: Orange, California • San Diego, California • San Francisco, California + 2 more

Conditions: Epilepsy, Seizures
Interventions: BHV-700; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Epilepsy
Interventions: Acupuncture intervention; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 15 Years to 60 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Epilepsy, Seizure
Interventions: Medilepsy® Chatbot AI-Enhanced, Medilepsy® Chatbot Standard; Other
Lead sponsor: University of Central Florida; Other
Eligibility: 14 Years to 24 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 2
States / cities: Orlando, Florida

Conditions: Epilepsy, Partial
Interventions: lamotrigine, 300 mg/day, lamotrigine, 250 mg/day; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 13 Years and older
Enrollment: 226 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 67
States / cities: Alabaster, Alabama • Litchfield Park, Arizona • Mesa, Arizona + 56 more

Conditions: Treatment Resistant Depression
Interventions: FEAST, FEAST RP; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 22 Years to 90 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Cortical Dysplasia
Interventions: Classical ketogenic diet; Dietary Supplement
Lead sponsor: University College, London; Other
Eligibility: 3 Years to 15 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Epilepsy; Seizure, Sleep
Interventions: NextSense EEG-enabled earbuds; Device
Lead sponsor: NextSense, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Seizures
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 7 Years to 35 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Ametropia, Myopia, Hyperopia, Astigmatism, Presbyopia
Interventions: Apioc Contact Lens Design; Device
Lead sponsor: Lentechs, LLC; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Brain Injury, Seizures, Cerebral Palsy
Interventions: Not listed
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 1 Day to 36 Months
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Traumatic Brain Injury, Subarachnoid Hemorrhage
Interventions: Levetiracetam, Phenytoin; Drug
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Epilepsy, Status Epilepticus, Epilepsia Partialis Continua, Epilepsia Partialis Continua, Refractory (Medically)
Interventions: Low frequency repeated TMS (LF-rTMS); Device
Lead sponsor: Baptist Health South Florida; Other
Eligibility: 18 Years to 80 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Epilepsies, Partial
Interventions: Lyrica (pregabalin), placebo; Drug
Lead sponsor: Pfizer's Upjohn has merged with Mylan to form Viatris Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 187 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2020
U.S. locations: 103
States / cities: Mobile, Alabama • Northport, Alabama • Tuscaloosa, Alabama + 57 more

Conditions: Seizures, Epilepsies, Partial, Epilepsy, Complex Partial, Epilepsy, Generalized, Epilepsy
Interventions: Placebo, Vanquix Auto-Injector (Diazepam Injection); Drug
Lead sponsor: Pfizer; Industry
Eligibility: 2 Years and older
Enrollment: 234 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2014
U.S. locations: 86
States / cities: Northport, Alabama • Little Rock, Arkansas • Irvine, California + 44 more

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Pre-oxygenation and Measures of Gas Exchanges During Seizures in the Epilepsy Monitoring Unit

Title: Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST)

Reducing Spread of COVID-19 in a University Community Setting: Role of a Low-Cost Reusable Form-Fitting Fabric Mask

Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care Pathways

Phase I Trail for Intramuscular Administration of Midazolam Using An Autoinjector

A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) & Refractory Partial-onset Seizures

Baseline Performance and Fitting Parameters for Sonova Products

Study to Evaluate the Efficacy and Safety of Perampanel as Monotherapy or First Adjunctive Therapy in Subjects With Partial Onset Seizures With or Without Secondarily Generalized Seizures or With Primary Generalized Tonic-Clonic Seizures

Internet Administration of the Modified Atkins Diet for Adults With Intractable Epilepsy

Detecting Absence Seizures Using Eye Tracking

BHV-7000 Responsive Neurostimulation System (RNS) Study

Clinical and Electrographic Changes in Responsive Neurostimulation System (RNS) Patients with Acupuncture Treatment

AI-Based Mobile Intervention on Medication Non-Adherence and Transition

Conversion To Monotherapy With Lamictal Extended Release Tablets For Treatment Of Partial Epilepsy

Enhanced Spatial Targeting in ECT Utilizing FEAST

Evaluating Dietary Intervention Before surgicaL Treatment for Epilepsy

Earbud EEG Feasibility Study

Magnetoencephalography in Absence Seizures

Apioc Contact Lens Feasibility

Study of Bedside EEG to Evaluate Brain Injury in Premature Newborns

Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention

Repeated TMS at Low Frequencies to Reduce Seizure Occurrence

Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo

Efficacy and Safety of Diazepam in the Management of Refractory Epilepsy in Selected Patients Who Require Intermittent Medical Intervention for Acute Repetitive Seizures.