- Conditions
- ST-segment Elevation Myocardial Infarction (STEMI), Cardiogenic Shock
- Interventions
- Impella CP®, Standard of Care
- Device · Other
- Lead sponsor
- Abiomed Inc.
- Industry
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
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Showing 25–48
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- Conditions
- Heart Failure, Cardiomyopathy
- Interventions
- Not listed
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Right Heart Catheterization
- Interventions
- SimpleSense
- Device
- Lead sponsor
- Nanowear Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Valhalla, New York
- Conditions
- Cardiogenic Shock, Acute; Myocardial Infarction, Complications
- Interventions
- data collection of clinically available procedures
- Other
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
- Conditions
- Cardiogenic Shock, Heart Failure, Inflammation
- Interventions
- Methylprednisone, Standard of Care (SOC)
- Drug · Other
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Cardiogenic Shock, Mitral Regurgitation
- Interventions
- Transcatheter edge-to-edge repair, Medical therapy
- Device · Other
- Lead sponsor
- Ottawa Heart Institute Research Corporation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 144 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2028
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Heart Failure, Cardiogenic Shock
- Interventions
- 1:1 Randomization to receive milrinone
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Cardiogenic Shock
- Interventions
- Vasopressor, Inotrope, Acute Mechanical Circulatory Support Devices
- Drug · Device
- Lead sponsor
- Tufts Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 5,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2026
- U.S. locations
- 16
- States / cities
- Weston, Florida • Chicago, Illinois • Portland, Maine + 10 more
- Conditions
- Cardiogenic Shock, Decompensated Heart Failure
- Interventions
- Measuring Pressure Volume Loop Pre and Post Device Placement
- Other
- Lead sponsor
- Cedars-Sinai Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Heart Failure, Cardiogenic Shock, Congenital Heart Disease, Cardiomyopathies
- Interventions
- Cardiohelp device (VA-ECMO), Heparin, Bivalirudin
- Device · Drug
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 0 Years to 16 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 5
- States / cities
- Palo Alto, California • New York, New York • Durham, North Carolina + 2 more
- Conditions
- Respiratory Failure, Respiratory Arrest, Respiratory Distress Syndrome, Acute Respiratory Failure, Acute Respiratory Failure With Hypoxia, Acute Respiratory Failure With Hypercapnia, Acute Respiratory Failure Post Surgical, Acute Respiratory Failure Postprocedural, Acute Respiratory Failure Following Trauma and Surgery, Acute Respiratory Failure Requiring Reintubation, Acute Respiratory Failure Post Traumatic, Acute Respiratory Decompensation, Shock, Shock, Septic, Shock, Cardiogenic, Acute Cardiac Failure, Multi Organ Failure, Acute Kidney Failure
- Interventions
- Observational retrospective cohort to describe data validity; and Data reliability; and Completeness of the data
- Other
- Lead sponsor
- Efficacy Care R&D Ltd
- Industry
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 50,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Acute Respiratory Distress Syndrome, Shock, Ventilatory Failure, Cardiogenic Pulmonary Edema
- Interventions
- Non invasive ventilation using a helmet hyperbaric device, Noninvasive ventilation via facemask
- Device · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 83 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Cardiogenic Shock
- Interventions
- Istaroxime, Placebo
- Drug
- Lead sponsor
- Windtree Therapeutics
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • Portland, Oregon
- Conditions
- Shock, Cardiogenic
- Interventions
- Tilarginine Acetate Injection intravenous infusion
- Drug
- Lead sponsor
- Arginox Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 658 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 83
- States / cities
- Mobile, Alabama • Fort Smith, Arizona • Mesa, Arizona + 68 more
- Conditions
- Cardiogenic Shock, Acute Myocardial Infarction
- Interventions
- Not listed
- Lead sponsor
- STAVROS G DRAKOS
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 2
- States / cities
- Weston, Florida • Falls Church, Virginia
- Conditions
- Cardiogenic Shock, STEMI
- Interventions
- SSO2 Downstream System, PCI + Impella
- Device · Procedure
- Lead sponsor
- TherOx
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 7
- States / cities
- Miami, Florida • Springfield, Massachusetts • Detroit, Michigan + 4 more
- Conditions
- Heart Failure, Cardiogenic Shock
- Interventions
- Not listed
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,089 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2020
- U.S. locations
- 7
- States / cities
- Aurora, Colorado • Minneapolis, Minnesota • St Louis, Missouri + 4 more
- Conditions
- Cardiogenic Shock
- Interventions
- Istaroxime, Placebo
- Drug
- Lead sponsor
- Windtree Therapeutics
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Percutaneous Large Hole Vascular Closure
- Interventions
- PPCI, Cardiogenic shock
- Device
- Lead sponsor
- Vivasure Medical Limited
- Industry
- Eligibility
- 19 Years and older
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 4
- States / cities
- Ridgewood, New Jersey • Buffalo, New York • Stony Brook, New York + 1 more
- Conditions
- ST Elevation Myocardial Infarction, Cardiovascular Diseases
- Interventions
- No intervention, Interview, Survey
- Other
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 473 participants
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Circulatory Shock, Cardiovascular Shock
- Interventions
- Nitroglycerin Topical Product
- Drug
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 44 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Cardiogenic Shock
- Interventions
- Heparin, Without Heparin
- Drug · Other
- Lead sponsor
- Corewell Health East
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 46 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- Royal Oak, Michigan
- Conditions
- Cardiogenic Shock, Acute Myocardial Infarction, STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation MI, Heart Attack
- Interventions
- Not listed
- Lead sponsor
- Henry Ford Health System
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 406 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 75
- States / cities
- Birmingham, Alabama • Fayetteville, Arkansas • Little Rock, Arkansas + 61 more
- Conditions
- Cardiogenic Shock
- Interventions
- Impella-CP LV Vent
- Device
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2023
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania