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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Shoulder Arthroplasty Clear all
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Interscalene Block With Liposomal Bupivacaine vs. Interscalene Block With Bupivacaine and Adjuvants

NCT03845894
View directory record Official record
Conditions
Shoulder Arthroplasty
Interventions
Liposomal bupivacaine, Bupivacaine with adjuvants
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting Not applicable Interventional

Rehabilitation Following Reverse Total Shoulder Arthroplasty

NCT03804853
View directory record Official record
Conditions
Shoulder Osteoarthritis
Interventions
Rehabilitiation
Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
55 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Opioid Use in Shoulder Arthroplasty Patients: A Stratification and Algorithm

NCT03808025
View directory record Official record
Conditions
Opioid Use
Interventions
opioid education
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Jun 10, 2026, 2:12 PM EDT
Active, not recruiting Not applicable Interventional

Sling vs No Sling After Reverse Total Shoulder Arthroplasty

NCT06092996
View directory record Official record
Conditions
Shoulder Disease, Rotator Cuff Tear Arthropathy, Shoulder Osteoarthritis
Interventions
Time of Sling Use
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Not applicable Interventional Results available

Comparison of Glenoid Position Using SmartBones

NCT03035318
View directory record Official record
Conditions
Anatomic Total Shoulder Arthroplasty
Interventions
DePuy Global® Anchor Peg Glenoid Instrumentation, DePuy Global® Anchor Peg Instrumentation with SmartBone™, IRI with SmartBone™, RTI with SmartBone™, IRI with SmartBase
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 17, 2021 · Synced Jun 10, 2026, 2:12 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

TSA Versus RSA in Patients >75

NCT04827277
View directory record Official record
Conditions
Total Shoulder Arthoplasty
Interventions
Reverse Total Shoulder Replacement, Anatomic Total Shoulder Replacement
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
75 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 31, 2021 · Synced Jun 10, 2026, 2:12 PM EDT
Enrolling by invitation No phase listed Observational

MDR - Comprehensive Reverse/Versa Dial Ti Glenosphere

NCT04003272
View directory record Official record
Conditions
Shoulder Pain, Shoulder Injuries, Shoulder Fractures, Shoulder Arthritis, Shoulder Disease
Interventions
Comprehensive Reverse Versa-Dial Titanium Glenosphere
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2035
U.S. locations
2
States / cities
Louisville, Kentucky • Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers Results available

Opioid-Free Pain Protocol After Shoulder Arthroplasty

NCT05488847
View directory record Official record
Conditions
Shoulder Arthropathy, Shoulder Pain
Interventions
Celecoxib, Pregabalin, Tramadol, Dexamethasone, Acetaminophen, Ropivicaine, Epinephrine, Ketorolac, Tizanidine, Magnesium, Ibuprofen, Oxycodone Hydrochloride 5 Mg
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Phase 3 Interventional Results available

Efficacy, Safety, and Pharmacokinetics of Brachial Plexus Block With EXPAREL in Shoulder Surgery

NCT02713230
View directory record Official record
Conditions
Pain
Interventions
bupivacaine liposome injectable suspension, Placebo
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
17
States / cities
Mobile, Alabama • Englewood, Colorado • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting Not applicable Interventional

Post-incision Antimicrobial Wash vs C. Acnes in Shoulder Arthroplasty

NCT06831422
View directory record Official record
Conditions
Shoulder Arthroplasty, Positive C. Acnes Culture
Interventions
Povidone-Iodine, Hydrogen Peroxide, Xperience Antimicrobial Wash, Bacterial Cultures, Shoulder Arthroplasty
Device · Diagnostic Test · Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Jun 10, 2026, 2:12 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

This is a 2 Year Follow up Clinical and Radiographic Analysis of a Novel All Polyethelene Glenoid Component in Standard Total Shoulder Arthroplasty.

NCT01313741
View directory record Official record
Conditions
The Primary Disease Process Being Studied is Shoulder OA and the Effect of an All Polyethelene Glenoid Component on Shoulder Arthroplasty
Interventions
Shoulder arthroplasty with anchor peg glenoid
Device
Lead sponsor
Knoxville Orthopedic Clinic
Other
Eligibility
40 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 13, 2011 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Not applicable Interventional Results available

Hydrogen Peroxide to the Wound Following Surgical Incision Affecting Cultures in Primary Shoulder Arthroplast

NCT04609306
View directory record Official record
Conditions
Primary Anatomic or Reverse Total Shoulder Arthroplasty
Interventions
H2O2 application to incision
Other
Lead sponsor
University of Florida
Other
Eligibility
40 Years to 90 Years · Male only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 21, 2024 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting Not applicable Interventional

Cryoneurolysis of the Suprascapular Nerve for Perioperative Pain Control After Receiving a Reverse Total Shoulder Arthroplasty (RTSA)

NCT07125833
View directory record Official record
Conditions
Degenerative Joint Disease of Shoulder
Interventions
Cryoneurolysis, No cryoneurolysis
Device · Other
Lead sponsor
North Texas Medical Research Institute, PLLC
Other
Eligibility
30 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rockwall, Texas
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Jun 10, 2026, 2:12 PM EDT
Terminated Not applicable Interventional

Onlay Versus Inlay Humeral Component in Reverse Total Shoulder Arthroplasty

NCT05297305
View directory record Official record
Conditions
Arthritis Shoulder, Rotator Cuff Injuries
Interventions
Tornier Ascend Flex stem, Tornier Perform Stem Reverse+
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting No phase listed Observational

Hospital for Special Surgery Shoulder Arthroplasty Cohort

NCT00527839
View directory record Official record
Conditions
Shoulder Arthroplasty
Interventions
Not listed
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Terminated Phase 4 Interventional

Daptomycin Use for Antimicrobial Prophylaxis in Methicillin Resistant Staphylococcus Aureus (MRSA) Colonized Adult Patients Undergoing Primary Elective Hip, Knee, or Shoulder Arthroplasty

NCT01196169
View directory record Official record
Conditions
Staphylococcal Infections, Methicillin-resistant Staphylococcus Aureus
Interventions
Daptomycin, Vancomycin
Drug
Lead sponsor
Mountain Home Research & Education Corporation
Other
Eligibility
18 Years to 90 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Johnson City, Tennessee • Mountain Home, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 2, 2014 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting Not applicable Interventional

Innovating Physical Therapy: A Pilot Study on Band Connect's Impact on Compliance, Satisfaction, and Revenue

NCT06733480
View directory record Official record
Conditions
Rotator Cuff Tears, Anatomic Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty
Interventions
Band Connect
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
499 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Completed No phase listed Observational Results available

Post- Surgery Recovery: Nerve Blocks w/ Sedation vs. Nerve Block w/ Either Sedation/Gen. Anesthesia

NCT02602080
View directory record Official record
Conditions
Nausea, Emesis
Interventions
Not listed
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 99 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Jun 10, 2026, 2:12 PM EDT
Terminated Phase 4 Interventional

Pain Management After Total Shoulder Arthroplasty

NCT03219983
View directory record Official record
Conditions
Glenohumeral Arthritis, Total Shoulder Arthroplasty
Interventions
Ropivacaine, liposomal bupivacaine
Drug
Lead sponsor
The Christ Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Jun 10, 2026, 2:12 PM EDT
Completed No phase listed Observational

Glenoid Bone Grafting for RTSA: Clinical & Radiographic Outcomes

NCT03151109
View directory record Official record
Conditions
Osteo Arthritis Shoulders
Interventions
CT Scan
Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Jun 10, 2026, 2:12 PM EDT
Completed No phase listed Observational

Comparison of Pain Relief After Non Stimulating Interscalene Catheter Placement vs Stimulating Catheter Placement in Total Shoulder Arthroplasty.

NCT01122732
View directory record Official record
Conditions
Pain, Shoulder, Arthroplasty
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 90 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 31, 2016 · Synced Jun 10, 2026, 2:12 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Long Term Outcomes Follow-up of Glenoid Anchor Peg Component Fixation

NCT02983357
View directory record Official record
Conditions
Arthritis
Interventions
CT, X-Ray, Physical assessment, Questionnaire
Radiation · Other
Lead sponsor
University of Nebraska
Other
Eligibility
44 Years to 94 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties

NCT05868330
View directory record Official record
Conditions
Post Operative Pain, Anesthesia, Nerve Block, Shoulder Osteoarthritis
Interventions
Interscalene Catheter, Exparel Single Shot Interscalene Block
Procedure
Lead sponsor
Melinda Seering
Other
Eligibility
18 Years to 90 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Not applicable Interventional

Efficacy of Surgical Diathermy in Eradicating Cutibacterium Acnes From Surgical Skin Incision During Shoulder Arthroplasty

NCT04608916
View directory record Official record
Conditions
Infection, Bacterial
Interventions
Using surgical diathermy to make skin incision, Using scalpel blade to make skin incision
Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older · Male only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Jun 10, 2026, 2:12 PM EDT