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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Signs of Developmental Delay Clear all
Terminated No phase listed Observational

Hereditary Deficits in Auditory Processing Leading to Language Impairment

NCT00004570
View directory record Official record
Conditions
Auditory Perceptual Disorder, Language Delay, Language Disorder
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
6 Years to 85 Years
Enrollment
875 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 19, 2018 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study: A Telehealth Intervention for Caregivers of Infants With Early Signs of Autism Spectrum Disorder

NCT03592654
View directory record Official record
Conditions
Autism Spectrum Disorder, Developmental Delay
Interventions
infant telehelp
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
5 Months to 12 Months
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SmarToyGym: Smart Detection of Atypical Toy-oriented Actions in At-risk Infants

NCT02813889
View directory record Official record
Conditions
Cerebral Palsy, Developmental Delay, Stroke, Fine Motor Delay, Infant Development, Other Development Delays
Interventions
SmarToyGym
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
3 Months to 11 Months
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional Results available

Efficacy of the START-Play Program for Infants With Neuromotor Disorders

NCT02593825
View directory record Official record
Conditions
Cerebral Palsy, Developmental Delay, Infant Development
Interventions
START-Play intervention, Business as usual
Behavioral
Lead sponsor
Duquesne University
Other
Eligibility
7 Months to 16 Months
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 17, 2024 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Phase 2 Interventional

18 Month Follow Up of Preterm Infants Enrolled in the Cord Clamping Study

NCT01426698
View directory record Official record
Conditions
Developmental Delay
Interventions
delayed cord clamping
Procedure
Lead sponsor
University of Rhode Island
Other
Eligibility
24 Weeks to 31 Weeks
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 4, 2014 · Synced Sep 17, 2026, 8:54 AM EDT
Not listed No phase listed Observational

Validation of a Salivary miRNA Diagnostic Test for ASD

NCT05418023
View directory record Official record
Conditions
Autism Spectrum Disorder, Developmental Delay
Interventions
Salivary Collection, Adaptive Assessment, Medical and Demographic questionnaire, Autism Assessment, Intellectual Development Assessment
Other
Lead sponsor
Quadrant Biosciences Inc.
Industry
Eligibility
18 Months to 7 Years
Enrollment
6,604 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
16
States / cities
Santa Ana, California • Atlanta, Georgia • Chicago, Illinois + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 17, 2026, 8:54 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Developmental Trajectories of Reinforcer Pathology and Childhood Obesity

NCT07229508
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Not listed
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
8 Years to 11 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Phase 4 Interventional Results available

A Pilot Study of Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging

NCT02633241
View directory record Official record
Conditions
Epilepsy, Cerebral Palsy, Developmental Delay
Interventions
Dexmedetomidine bolus and high infusion-Propofol, Dexmedetomidine bolus and low infusion-Propofol, Dexmedetomidine bolus only - Propofol
Drug
Lead sponsor
Joseph Cravero
Other
Eligibility
1 Year to 12 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 26, 2023 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Establishing the Clinical Utility of First StepDx PLUS and NextStepDx PLUS Study

NCT02414438
View directory record Official record
Conditions
Intellectual Disability, Developmental Delay
Interventions
FirstStepDX PLUS and NextStepDX PLUS Webinar, FirstStepDX PLUS and NextStepDX PLUS Test Results
Other
Lead sponsor
Qure Healthcare, LLC
Industry
Eligibility
Up to 99 Years
Enrollment
217 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Rafael, California
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 17, 2026, 8:54 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Mitochondrial Dysfunction in Autism Spectrum Disorder

NCT02000284
View directory record Official record
Conditions
Autism Spectrum Disorder, Autism, Mitochondrial Disease, Developmental Delay
Interventions
Not listed
Lead sponsor
University of Arkansas
Other
Eligibility
0 Years to 17 Years
Enrollment
297 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2027
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional Results available

Can Novel Telemedicine Tools Reduce Disparities Related to Early Identification of Autism

NCT03847337
View directory record Official record
Conditions
Autism Spectrum Disorder, Developmental Delay
Interventions
Telehealth-Screening Tool for Autism in Toddlers (STAT), Telehealth-Autism Spectrum Disorder-Pediatrics (ASD-PEDS)
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
15 Months to 3 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 28, 2022 · Synced Sep 17, 2026, 8:54 AM EDT
Completed No phase listed Observational

Occupational Therapy in the Context of Head Start

NCT01975506
View directory record Official record
Conditions
Developmental Delay
Interventions
Not listed
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional Results available

North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2

NCT03548779
View directory record Official record
Conditions
Epilepsy; Seizure, Neuromuscular Diseases, Brain Malformation, Intellectual Disability, Autism Spectrum Disorder, Hypotonia, Inborn Errors of Metabolism, Movement Disorders, Genetic Disease, Development Delay, Chromosome Abnormality, Hearing Loss, Dysmorphic Features, Skeletal Dysplasia, Congenital Abnormality, Microcephaly, Macrocephaly
Interventions
Pre-visit prep, usual care + exome seq
Behavioral · Diagnostic Test
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
0 Years and older
Enrollment
548 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
3
States / cities
Asheville, North Carolina • Chapel Hill, North Carolina • Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated May 12, 2025 · Synced Sep 17, 2026, 8:54 AM EDT
Completed No phase listed Observational

Pediatric Patients With Metabolic or Other Genetic Disorders

NCT02769949
View directory record Official record
Conditions
Genetic Disorder, Asperger Disorder, Autism Spectrum Disorder, Fragile X Syndrome, Developmental Delay
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
1 Year to 99 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional

Implementation of Electronic Shared Decision-Making Support for Early Intervention

NCT04562038
View directory record Official record
Conditions
Child Development Disorder, Development Delay
Interventions
Young Children's Participation and Environment Measure (YC-PEM) electronic patient-reported outcome (e-PRO)
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
3 Months to 36 Months
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Sep 17, 2026, 8:54 AM EDT
Completed No phase listed Observational

Natural History Study of Smith-Magenis Syndrome

NCT00013559
View directory record Official record
Conditions
Smith-Magenis Syndrome (SMS)
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
1 Month to 115 Years
Enrollment
593 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 17, 2026, 8:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Salivary miRNA Diagnostic Test for Autism

NCT02832557
View directory record Official record
Conditions
Autism Spectrum Disorder, Developmental Delay
Interventions
Salivary collection, Vineland Adaptive Behavior Scale-III Assessment, Medical history questionaire, Autism Diagnostic Observation Schedule -2nd edition (ADOS-2), Mullen Scales of Early Learning
Other
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
24 Months to 48 Months
Enrollment
998 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Sep 17, 2026, 8:54 AM EDT
Recruiting No phase listed Observational

Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders

NCT07493096
View directory record Official record
Conditions
Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder), Cerebral Palsy (CP), Cerebral Palsy Hemiparetic Cerebral Palsy Spasticity Gait Disorders, Neurologic Postural Balance Impairment, Cerebral Palsy Infantile, Cerebral Palsy Spastic Hemiplegic, Cerebral Palsy, Dyskinetic, Autism Spectrum Disorder, Autism Spectrum Disorder (ASD, Hypoxic Ischemic Encephalopathy, Hypoxic Ischemic Encephalopathy (HIE), Traumatic Brain Injury (TBI), Sensory Processing Disorder, Chromosomal Abnormalities, Genetic Disorders, Down Syndrome (Trisomy 21), Fragile X Syndrome (FXS), RETT Syndrome With Proven MECP2 Mutation, Williams Syndrome, 22q11.2 Deletion Syndrome, Sensorimotor Integration
Interventions
Not listed
Lead sponsor
Healing Hope International
Other
Eligibility
4 Years to 12 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2036
U.S. locations
1
States / cities
The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 17, 2026, 8:54 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Combined Oral Motor Stimulation and Language on Preterm Infant Feeding

NCT05861531
View directory record Official record
Conditions
Language Delay, Language Development, Feeding; Difficult, Newborn, Mother-Infant Interaction, Maternal Behavior
Interventions
Oromotor stimulation, Reading curriculum, LENA recording, LENA linguistic feedback, No oromotor stimulation
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
23 Weeks to 30 Weeks
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 17, 2026, 8:54 AM EDT
Recruiting No phase listed Observational

Longitudinal Study of Neurogenetic Disorders

NCT03492060
View directory record Official record
Conditions
Neurodevelopmental Disorders, Intellectual Disability, Developmental Delay, Autism Spectrum Disorder, Seizures, Hypertonia, Muscle, Hypotonia
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 17, 2026, 8:54 AM EDT
Terminated Not applicable Interventional

Maternal Voice and Quantitative EEG (qEEG)

NCT05391633
View directory record Official record
Conditions
Prematurity, Development Delay, Premature Birth
Interventions
Recorded Maternal Voice, Placebo Recording
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
28 Weeks to 33 Weeks
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Sep 17, 2026, 8:54 AM EDT
Completed Not applicable Interventional Results available

Dietary Supplements for the Treatment of Angelman Syndrome

NCT00348933
View directory record Official record
Conditions
Angelman Syndrome, Nervous System Diseases
Interventions
Betaine, Creatine, Metafolin, Vitamin B12
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
1 Day to 5 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
4
States / cities
San Diego, California • Boston, Massachusetts • Greenwood, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2012 · Synced Sep 17, 2026, 8:54 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Exploratory Trial of a Pediatric Web-Based Care Planning Guide

NCT06458959
View directory record Official record
Conditions
Developmental Disabilities, Developmental Delay
Interventions
PEM+
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
223 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 17, 2026, 8:54 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Coaching in Early Development Project

NCT06347666
View directory record Official record
Conditions
Developmental Delay
Interventions
Caregiver coaching
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
12 Months to 6 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Sep 17, 2026, 8:54 AM EDT