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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Skin Laxity Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Clinical Feasibility Study to Evaluate the Safety and Performance of the Profound Matrix System

NCT06157567
View directory record Official record
Conditions
Skin Laxity, Wrinkle, Skin Condition
Interventions
Profound Matrix
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
4
States / cities
Jacksonville, Florida • Marlborough, Massachusetts • Fayetteville, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Jul 22, 2026, 12:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Evaluation of the Ulthera® System for Treatment of the Knees

NCT01708434
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera® System
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Jul 22, 2026, 12:26 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Evaluation of Ocular Surface Changes Following RF Electrocoagulation Treatment of the Periorbital Region

NCT03280069
View directory record Official record
Conditions
Skin Laxity, Meibomian Gland Dysfunction
Interventions
THERMIeyes® 20 RF System
Device
Lead sponsor
Ophthalmic Consultants of Long Island
Other
Eligibility
40 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Lynbrook, New York
Source: ClinicalTrials.gov public record
Updated Sep 11, 2017 · Synced Jul 22, 2026, 12:26 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluate the Safety and Efficacy of AGE Serum in Post-menopausal Patients on Hormone Replacement Therapy Taking Glucagon-like Peptide-1 Agonist

NCT07558603
View directory record Official record
Conditions
Laxity; Skin
Interventions
On GLP1 plus HRT, On GLP1 Only
Drug
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Jul 22, 2026, 12:26 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Mechanical Coring to Achieve Directional Skin Tightening

NCT04910945
View directory record Official record
Conditions
Skin Tightening, Healthy Volunteers
Interventions
VENUS AIME (RoboCor)
Device
Lead sponsor
Venus Concept
Industry
Eligibility
30 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
3
States / cities
Los Altos, California • San Jose, California • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Jul 22, 2026, 12:26 PM EDT
Completed Not applicable Interventional Results available

Feasibility Study To Collect Safety And Preliminary Efficacy Data For A Radiofrequency Microneedling Device

NCT05254210
View directory record Official record
Conditions
Wrinkles, Fine Lines, Crepey Skin, Acne Scars, Active Acne, Enlarged Pores, Loose Skin
Interventions
RF Device (Potenza™)
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
West Hollywood, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Jul 22, 2026, 12:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bausch Health Thermage FXL for Use on Lower Face and Submentum Area

NCT04606368
View directory record Official record
Conditions
Skin Wrinkling
Interventions
Thermage FLX
Device
Lead sponsor
Lorraine Hickson
Other
Eligibility
40 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Jul 22, 2026, 12:26 PM EDT
Completed No phase listed Observational

Durability and Safety of CCH With Two Different Injection Techniques in Cellulite With Laxity

NCT05249257
View directory record Official record
Conditions
Cellulite, Laxity; Skin, Edematous Fibrosclerotic Panniculopathy
Interventions
Not listed
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years to 55 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
3
States / cities
Coral Gables, Florida • Metairie, Louisiana • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 18, 2023 · Synced Jul 22, 2026, 12:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Ulthera Treatment of the Buttocks and Thighs

NCT01708460
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera System Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Jul 22, 2026, 12:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparison of the Effect of Suture Material on Blepharoplasty Incision

NCT04585217
View directory record Official record
Conditions
Dermatochalasis, Ptosis, Eyelid
Interventions
Randomized laterality of suture materials for closure (6-0 polypropylene monofilament suture vs fast absorbing gut suture on right eyelid)
Procedure
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years to 89 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2023 · Synced Jul 22, 2026, 12:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Evoke Radiofrequency Device for Improvement of Skin Appearance

NCT04721600
View directory record Official record
Conditions
Skin Laxity
Interventions
Evoke Radiofrequency Device
Device
Lead sponsor
InMode MD Ltd.
Industry
Eligibility
35 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Jul 22, 2026, 12:26 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

High Intensity Ultrasound for the Treatment of Upper Inner Arm Skin Laxity

NCT05355714
View directory record Official record
Conditions
Skin Laxity
Interventions
Sofwave, Ultherapy
Device
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
35 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 1, 2022 · Synced Jul 22, 2026, 12:26 PM EDT
Not listed Not applicable Interventional

Telemedicine Follow-up for Routine, Low-Risk Oculoplastic Surgery

NCT04235803
View directory record Official record
Conditions
Eyelid Diseases, Ptosis, Eyelid, Blepharoptosis, Dermatochalasis, Ectropion, Entropion, Eyelid Tumor, Skin Cancer, Eyelid, Floppy Eyelid Syndrome
Interventions
Telemedicine follow-up
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Jul 22, 2026, 12:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

BTL-785F Device for Non-invasive Reduction of Wrinkles

NCT05519124
View directory record Official record
Conditions
Wrinkle
Interventions
BTL-785-7
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
New York, New York • Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 30, 2022 · Synced Jul 22, 2026, 12:26 PM EDT
Not listed Not applicable Interventional

Histological Study of the Effects of a 2910 nm Fiber Laser Technology

NCT06317766
View directory record Official record
Conditions
Skin Laxity
Interventions
2910 nm Fiber Laser Treatment; Pre-Clinical Histology Evaluation, 2910 nm Fiber Laser Treatment; Part 2 Histology Evaluation
Device
Lead sponsor
FA Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Jul 22, 2026, 12:26 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

CCH Treatment of Cellulite in the Presence of Dermal Laxity With Comparison Between Two (2) Different Injection Techniques

NCT04580303
View directory record Official record
Conditions
Edematous Fibrosclerotic Panniculopathy, Cellulite, Laxity; Skin
Interventions
collagenase clostridium histolyticum
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years to 55 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
3
States / cities
Coral Gables, Florida • Metairie, Louisiana • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 27, 2022 · Synced Jul 22, 2026, 12:26 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Injectable Poly-L-Lactic Acid for Volumization and Adipogenesis of the Hip Dell

NCT05269654
View directory record Official record
Conditions
Skin Laxity
Interventions
injectable poly-L-lactic acid, Normal Saline
Device · Other
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
30 Years to 60 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 7, 2022 · Synced Jul 22, 2026, 12:26 PM EDT
Completed Not applicable Interventional

Pilot Evaluation of the Cynosure Potenza™ System for Treatment of Cosmetic Dermatologic Skin Conditions

NCT05847530
View directory record Official record
Conditions
Wrinkles, Scars, Stretch Marks, Pigmentation, Skin Laxity
Interventions
Potenza, Icon
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Jul 22, 2026, 12:26 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Bipolar RF Microneedling for Improved Laxity and Lift of the Submental and Neck Tissue and Effect on Elastin

NCT04245696
View directory record Official record
Conditions
Skin Laxity
Interventions
Dermal Handpiece / SubQ Handpiece
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
21 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Marlborough, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Jul 22, 2026, 12:26 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the Ulthera® System and Efficacy Correlation to Morphological Differences

NCT03599349
View directory record Official record
Conditions
Facial and Neck Skin Laxity
Interventions
Microfocused ultrasound w/ visualization
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2019 · Synced Jul 22, 2026, 12:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

A Retrospective Study to Evaluate the Effectiveness of the Ulthera System

NCT01519934
View directory record Official record
Conditions
Skin Laxity, Wrinkles
Interventions
Not listed
Lead sponsor
Ulthera, Inc
Industry
Eligibility
25 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2017 · Synced Jul 22, 2026, 12:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lifting and Tightening of the Face and Neck Following an Increased Density Treatment

NCT01519206
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera System Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 10, 2017 · Synced Jul 22, 2026, 12:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Treatment of Post-surgery and Surgery Naive Patients Who Failed to Respond to a Previous Ulthera Treatment

NCT01708252
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera System Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Jul 22, 2026, 12:26 PM EDT
Completed Not applicable Interventional Results available

Rollover Study to Evaluate Histological Results of Radiofrequency Device Treatments on the Flanks

NCT04881149
View directory record Official record
Conditions
Skin Laxity
Interventions
TempSure treatment
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2022 · Synced Jul 22, 2026, 12:26 PM EDT