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ClinicalTrials.gov public records Last synced Sep 30, 2026, 10:26 AM EDT

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Showing 49–72 of 115 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep Apnea Central Clear all
Terminated Not applicable Interventional

A Trial to Evaluate a Device for the Treatment of OSA and Snoring

NCT01772017
View directory record Official record
Conditions
Obstructive Sleep Apnea, Snoring
Interventions
Tongue Advancement Retainer Device
Device
Lead sponsor
Sleepy, Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
San Diego, California • Visalia, California
Source: ClinicalTrials.gov public record
Updated Nov 24, 2015 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diagnosis of Sleep-Related Respiratory Disorders in Patients With Narcotic Medications

NCT03670914
View directory record Official record
Conditions
Narcotic Use, Central Sleep Apnea
Interventions
WatchPAT 200
Diagnostic Test
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 30, 2026, 10:26 AM EDT
Completed No phase listed Observational

World Trade Center (WTC) CHEST

NCT01466218
View directory record Official record
Conditions
Pulmonary Disease, Cardiac Disease, Cardiopulmonary Disease, Obstructive Sleep Apnea, Cardiovascular Disease
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
40 Years and older
Enrollment
1,012 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2014 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Treating Sleep Apnea on Cognition in Patients With Dementia

NCT00477828
View directory record Official record
Conditions
Dementia, Sleep Apnea
Interventions
Continuous positive airway pressure
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years to 85 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2006
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 24, 2007 · Synced Sep 30, 2026, 10:26 AM EDT
Terminated Not applicable Interventional

Severe OSA Study (SOS)

NCT05445869
View directory record Official record
Conditions
Obstructive Sleep Apnea, Sleep Apnea
Interventions
ProSomnus® EVO Sleep and Snore Device
Device
Lead sponsor
ProSomnus Sleep Technologies
Industry
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
5
States / cities
Redwood City, California • Boston, Massachusetts • Minneapolis, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Sep 30, 2026, 10:26 AM EDT
Terminated Not applicable Interventional

Effect of Adaptive Servo Ventilation (ASV) on Survival and Hospital Admissions in Heart Failure

NCT01128816
View directory record Official record
Conditions
Sleep Apnea, Heart Failure
Interventions
Adaptive Servo Ventilation
Device
Lead sponsor
Toronto Rehabilitation Institute
Other
Eligibility
18 Years and older
Enrollment
732 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2022
U.S. locations
3
States / cities
Tucson, Arizona • Kalispell, Montana • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 22, 2022 · Synced Sep 30, 2026, 10:26 AM EDT
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment

NCT07210606
View directory record Official record
Conditions
Sleep Disordered Breathing, Able Bodied
Interventions
Trazodone + PAP therapy, Oxygen + PAP therapy
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Not applicable Interventional Results available

Bipap Automatic Servo Ventilation (autoSV) Advanced in Central Apnea Patients

NCT01199042
View directory record Official record
Conditions
Cheyne-Stokes Respiration, Sleep Apnea, Central
Interventions
BiPAP autoSV Advanced
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 75 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
3
States / cities
Wallingford, Connecticut • Louisville, Kentucky • Mason, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 28, 2016 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Not applicable Interventional Results available

Mild Cognitive Impairment and Obstructive Sleep Apnea

NCT01482351
View directory record Official record
Conditions
Obstructive Sleep Apnea, Mild Cognitive Impairment
Interventions
CPAP adherence intervention, Attention control intervention
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
55 Years to 89 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Abington, Pennsylvania • Philadelphia, Pennsylvania • Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Not applicable Interventional

Treating Sleep Apnea Induced Hypoxemia With Oxygen in Acute Stroke Patients

NCT03300063
View directory record Official record
Conditions
Stroke, Acute
Interventions
Low flow nocturnal oxygen
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effects of Naltrexone on Nocturnal Breathing Patterns at Altitude

NCT05037032
View directory record Official record
Conditions
Altitude, Sleep Apnea, Central
Interventions
Naltrexone Pill, Placebo
Drug
Lead sponsor
VA Loma Linda Health Care System
Federal
Eligibility
18 Years to 35 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Phase 2 Interventional Results available

Chronic Evaluation of Respicardia Therapy

NCT01124370
View directory record Official record
Conditions
Sleep Disordered Breathing, Cheyne Stokes Respiration, Periodic Breathing, Sleep Apnea, Central Sleep Apnea
Interventions
remedē (TM) system
Device
Lead sponsor
Respicardia, Inc.
Industry
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
5
States / cities
Lincoln, Nebraska • Columbus, Ohio • Lancaster, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated May 16, 2016 · Synced Sep 30, 2026, 10:26 AM EDT
Active, not recruiting No phase listed Observational

remedē System Therapy Study

NCT03884660
View directory record Official record
Conditions
Central Sleep Apnea
Interventions
remede System
Device
Lead sponsor
Respicardia, Inc.
Industry
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
29
States / cities
Phoenix, Arizona • Scottsdale, Arizona • San Francisco, California + 24 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Sleep and Breathing in the General Population - Chemical Stimuli

NCT04720547
View directory record Official record
Conditions
Sleep-disordered Breathing
Interventions
Zolpidem, No Treatment
Drug · Other
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 89 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Phase 2Phase 3 Interventional

Enabling Sleep Apnea Patient-Centered Care Via an Internet Intervention

NCT00662623
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
i-PAP, Usual Care (Standard Care)
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 13, 2016 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Not applicable Interventional

Sleep Disordered Breathing and Its Impact on Neuro-cognitive Performance and Quality of Life in Parkinson Disease

NCT02034357
View directory record Official record
Conditions
Parkinson's Disease, Sleep Disordered Breathing, Sleep Obstructive Apnea
Interventions
Neurocognitive function, Sleep evaluations
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 24, 2016 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Transmembrane Electromyography (TM-EMG) for the Assessment of Neuromuscular Function in the Oropharynx

NCT03986671
View directory record Official record
Conditions
Obstructive Sleep Apnea, Amyotrophic Lateral Sclerosis, Muscular Dystrophies, Healthy
Interventions
Transmembrane EMG Oropharynx Probe
Device
Lead sponsor
Powell Mansfield Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Not applicable Interventional

SIESTA (Sleep of Inpatients: Empower Staff to Act) for Acute Stroke Rehabilitation

NCT04254484
View directory record Official record
Conditions
Sleep, Sleep Disordered Breathing, Stroke
Interventions
SIESTA Rehab Education, ApneaLink
Behavioral · Diagnostic Test
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Phase 3 Interventional Results available

"Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA"

NCT02348606
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
JZP-110, Placebo oral tablet
Drug
Lead sponsor
Jazz Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
476 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
45
States / cities
Glendale, Arizona • Scottsdale, Arizona • Little Rock, Arkansas + 38 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Determinants of Age Related Breathing Instability During Non-Rapid-Eye-Movement (NREM) Sleep

NCT00732199
View directory record Official record
Conditions
Sleep Apnea, Age
Interventions
1) hyperventilation via noninvasive positive pressure ventilation 2) multiple trials of episodic hypoxia
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 28, 2017 · Synced Sep 30, 2026, 10:26 AM EDT
Completed No phase listed Observational

Pre-operative Polysomnography Assessment of Cardiac Surgery Inpatients

NCT00922168
View directory record Official record
Conditions
Sleep Disordered Breathing, Obstructive Sleep Apnea, Central Sleep Apnea
Interventions
Not listed
Lead sponsor
Cleveland Medical Devices Inc
Industry
Eligibility
Not listed
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Baltimore, Maryland • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 6, 2014 · Synced Sep 30, 2026, 10:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

World Trade Center Kidney-Link

NCT03234530
View directory record Official record
Conditions
Chronic Kidney Diseases, Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 75 Years
Enrollment
555 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 9, 2021 · Synced Sep 30, 2026, 10:26 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury

NCT02922894
View directory record Official record
Conditions
Sleep Apnea, Spinal Cord Injury
Interventions
Acute episodic hypoxia, Supplemental oxygen, Trazodone, Placebo, Sham
Procedure · Drug
Lead sponsor
John D. Dingell VA Medical Center
Federal
Eligibility
18 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 30, 2026, 10:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep, Aging and Risk for Alzheimer's Disease

NCT01962779
View directory record Official record
Conditions
Sleep Disordered Breathing, Alzheimer's Disease
Interventions
Continuous positive airway pressure (CPAP)
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
50 Years and older
Enrollment
235 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Sep 30, 2026, 10:26 AM EDT