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ClinicalTrials.gov public records Last synced Sep 27, 2026, 5:57 AM EDT

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Showing 1–24 of 2,593 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Sleep-Wake Disorders Clear all
Active, not recruiting Not applicable Interventional

Wearable Transcranial Electrical Stimulation (tES) for Insomnia

NCT06100185
View directory record Official record
Conditions
Insomnia
Interventions
PeakSleep, Sham
Device
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 70 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 27, 2026, 5:57 AM EDT
Recruiting Not applicable Interventional

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

NCT05663034
View directory record Official record
Conditions
Traumatic Brain Injury, Insomnia, Depression, Post-traumatic Stress, Sleep, Memory Impairment, Cognitive Behavioral Therapy, Concussion, Brain, Head Injury, Brain Injury Traumatic Mild
Interventions
Mindfulness-based treatment for insomnia (MBTI), Cognitive behavioral therapy for insomnia (CBT-I)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
5
States / cities
Eglin Air Force Base, Florida • Bethesda, Maryland • Fort Bragg, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 27, 2026, 5:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of Unattended Home Polysomnography and Comparison to In-laboratory Polysomnography in Pediatric Patients

NCT03473548
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Portable sleep monitor, In-laboratory Polysomnography
Device · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
5 Years to 12 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Sep 27, 2026, 5:57 AM EDT
Withdrawn Phase 1Phase 2 Interventional

Dex as Analgesic Adjuvant in OSA Patients

NCT03613558
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Dexmedetomidine, Placebo
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 2, 2018 · Synced Sep 27, 2026, 5:57 AM EDT
Recruiting Phase 4 Interventional

Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea

NCT02630121
View directory record Official record
Conditions
Sleep Apnea, Chronic Nasal Congestion
Interventions
Oxymetazoline Hydrochloride, Placebo
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Sep 27, 2026, 5:57 AM EDT
Completed Phase 4 Interventional Results available

A Study of Suvorexant in Patients With Multiple Sclerosis Fatigue and Insomnia

NCT03110315
View directory record Official record
Conditions
Multiple Sclerosis, Fatigue, Insomnia
Interventions
Suvorexant, Placebo
Drug
Lead sponsor
Theodore R. Brown, MD MPH
Other
Eligibility
18 Years to 75 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Kirkland, Washington
Source: ClinicalTrials.gov public record
Updated Feb 2, 2025 · Synced Sep 27, 2026, 5:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Lagged Relationships Between Sleep, Balance, and Cognition in Older Adults

NCT06584136
View directory record Official record
Conditions
Aging
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 95 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 27, 2026, 5:57 AM EDT
Withdrawn Phase 4 Interventional

Spironolactone to Improve Apnea and Cardiovascular Markers in Obstructive Sleep Apnea Patients

NCT04205136
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Spironolactone, Placebo
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Sep 27, 2026, 5:57 AM EDT
Completed Phase 1Phase 2 Interventional Results available

A Pilot Study of the Effects on Sleep Disordered Breathing (SDB) When Using the Drug Liraglutide for 4 Weeks

NCT01832532
View directory record Official record
Conditions
Sleep Apnea, Sleep Disordered Breathing
Interventions
liraglutide
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
18 Years to 60 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Sep 27, 2026, 5:57 AM EDT
Completed Not applicable Interventional Results available

Novel Treatment of Comorbid Insomnia and Sleep Apnea in Older Veterans

NCT02027558
View directory record Official record
Conditions
Insomnia, Apnea
Interventions
Insomnia treatment & PAP adherence, General sleep education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Sepulveda, California • West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 2, 2019 · Synced Sep 27, 2026, 5:57 AM EDT
Completed Not applicable Interventional Results available

Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients

NCT01284140
View directory record Official record
Conditions
Critical Illness, Sleep Deprivation, Respiratory Failure, Sleep Disorders, Circadian Rhythm
Interventions
Sleep and circadian rhythm promotion, Usual care
Behavioral
Lead sponsor
Brian Gehlbach
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Chicago, Illinois • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 6, 2018 · Synced Sep 27, 2026, 5:57 AM EDT
Enrolling by invitation Phase 3 Interventional Accepts healthy volunteers

Continuation Protocol for Obstructive Sleep Apnea (OSA)

NCT06566820
View directory record Official record
Conditions
OSA
Interventions
Aroxybutynin and Atomoxetine
Drug
Lead sponsor
Apnimed
Industry
Eligibility
18 Years and older
Enrollment
1,280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
93
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama • Chandler, Arizona + 80 more
Source: ClinicalTrials.gov public record
Updated May 12, 2025 · Synced Sep 27, 2026, 5:57 AM EDT
Completed No phase listed Observational

Effect of Continuous Positive Airway Pressure (CPAP) on Lower Esophageal Sphincter Pressure in Morbidly Obese Patients

NCT01099735
View directory record Official record
Conditions
Sleep Apnea, Gastroesophageal Reflux Disease
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 29, 2019 · Synced Sep 27, 2026, 5:57 AM EDT
Recruiting Phase 3 Interventional

A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 2

NCT07502443
View directory record Official record
Conditions
Narcolepsy Type 2
Interventions
ALKS 2680 Dose 1, ALKS 2680 Dose 2, ALKS 2680 Dose 3, Placebo
Drug
Lead sponsor
Alkermes, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
22
States / cities
Cullman, Alabama • Phoenix, Arizona • Los Angeles, California + 19 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 27, 2026, 5:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Management in Cancer Survivors

NCT00935376
View directory record Official record
Conditions
Insomnia
Interventions
Sleep Education Program, Mind-Body Bridging Program, Mindfulness Meditation Program
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 27, 2026, 5:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Articulated Oral Airway as an Aid to Mask Ventilation

NCT03144089
View directory record Official record
Conditions
Mask Ventilation, Airway Obstruction Upper, Airway Management
Interventions
Articulated Oral Airway, Guedel oral airway (active comparator)
Device
Lead sponsor
Ron Abrons
Other
Eligibility
18 Years to 99 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Sep 27, 2026, 5:57 AM EDT
Completed Not applicable Interventional Results available

Clinical Study for the BONGO Device in the Treatment of Obstructive Sleep Apnea (OSA)

NCT02878590
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
BONGO DEVICE
Device
Lead sponsor
InnoMed Healthscience Inc.
Industry
Eligibility
21 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Alameda, California
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Sep 27, 2026, 5:57 AM EDT
Completed Not applicable Interventional

A Computerized CBTi for Insomnia in Epilepsy

NCT03632889
View directory record Official record
Conditions
Epilepsy, Insomnia
Interventions
GoToSleep Program
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Sep 27, 2026, 5:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Trial to Evaluate the Effects of a Topical Roll-on and Diffuser Blend on Sleep Quality and Sleep Duration

NCT07779382
View directory record Official record
Conditions
Sleep Quality, Sleep Duration, Fatigue, Energy Levels, Overall Health and Well-Being
Interventions
Sleep Well Diffuser Blend followed by Sleep Well Roll-On
Dietary Supplement
Lead sponsor
Saie Beauty
Industry
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 27, 2026, 5:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating the Efficacy of PAP Therapy for Treating OSA in the Home Environment

NCT04744038
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Positive Airway Pressure (PAP) Therapy
Device
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 12, 2021 · Synced Sep 27, 2026, 5:57 AM EDT
Completed Phase 3 Interventional

Efficacy and Safety of M100907 on Sleep Maintenance Insomnia With a Sub-study in Stable Type II Diabetes Mellitus

NCT00495885
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
volinanserin (M100907), Placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
848 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated May 25, 2016 · Synced Sep 27, 2026, 5:57 AM EDT
Terminated Phase 2 Interventional

Efficacy and Safety Study of Adipiplon, Placebo and an Active Control in Primary Insomniacs

NCT00683436
View directory record Official record
Conditions
Primary Insomnia
Interventions
Adipiplon, Placebo, Ambien CR
Drug
Lead sponsor
Neurogen Corporation
Industry
Eligibility
21 Years to 64 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
9
States / cities
Pembroke Pines, Florida • South Miami, Florida • Atlanta, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2008 · Synced Sep 27, 2026, 5:57 AM EDT
Completed Phase 2 Interventional

A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Narcolepsy Type 1 (ALKS 2680-201)

NCT06358950
View directory record Official record
Conditions
Narcolepsy Type 1
Interventions
ALKS 2680, Placebo
Drug
Lead sponsor
Alkermes, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
29
States / cities
Los Angeles, California • Redwood City, California • San Francisco, California + 24 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 27, 2026, 5:57 AM EDT
Completed Not applicable Interventional

CBTI-CS: A Novel Cognitive-Behavioral Treatment for Insomnia in Cancer Survivors

NCT02756390
View directory record Official record
Conditions
Insomnia
Interventions
CBTI-CS, Sleep Hygiene, CBTI-CS via Telehealth
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 10, 2018 · Synced Sep 27, 2026, 5:57 AM EDT