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ClinicalTrials.gov public records Last synced Nov 11, 2026, 2:52 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 2,612 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Sleep Apnea, Nasal Obstruction
Interventions: turbinate cauterization; Procedure
Lead sponsor: Eastern Virginia Medical School; Other
Eligibility: 3 Years to 16 Years
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2020
U.S. locations: 1
States / cities: Norfolk, Virginia

Conditions: Delirium, Sleep Disturbance
Interventions: Nighttime Vital Sign EHR Alert, No EHR alert; Behavioral · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: Not listed
Enrollment: 1,436 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Excessive Sleepiness
Interventions: Armodafinil, Matching Placebo; Drug
Lead sponsor: Cephalon; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 385 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010
U.S. locations: 63
States / cities: Phoenix, Arizona • Tucson, Arizona • Hot Springs, Arkansas + 56 more

Conditions: Obstructive Sleep Apnea (OSA)
Interventions: Placebo oral capsule, DAW2020 oral capsule; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 21 Years to 70 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Head and Neck Cancer, Obstructive Sleep Apnea
Interventions: Nerve stimulation using nerve stimulation device and sterile wire electrode.; Device
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Restless Legs Syndrome, Restless Legs Syndrome (RLS)
Interventions: GSK1838262 Extended Release Tablets, Placebo; Drug
Lead sponsor: XenoPort, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 136 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 24
States / cities: Jasper, Alabama • San Diego, California • Hallandale, Florida + 20 more

Conditions: Obstructive Sleep Apnea
Interventions: Acetazolamide, Placebo; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Physician Fatigue
Interventions: SCS intervention schedule; Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 21 Years and older
Enrollment: 413 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 6
States / cities: Aurora, Colorado • Iowa City, Iowa • Boston, Massachusetts + 3 more

Conditions: Atopic Dermatitis, Sleep Disturbance
Interventions: Dupilumab; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 6 Years to 17 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Obstructive Sleep Apnea
Interventions: Expiratory Pressure Relief; Device
Lead sponsor: SleepRes Inc.; Industry
Eligibility: 18 Years to 70 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Murfreesboro, Tennessee

Conditions: Irritable Bowel Syndrome, Disorders of Gut-brain Interaction
Interventions: Gut-directed Hypnotherapy; Other
Lead sponsor: Children's Hospital at Montefiore; Other
Eligibility: 8 Years to 18 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Mahwah, New Jersey

Conditions: Insomnia
Interventions: suvorexant, placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 40 Years to 65 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression, Postpartum Depression, Prenatal Disorder, Circadian Dysregulation, Pregnancy Related, Sleep Disturbance
Interventions: Personalized Integrated Chronotherapy; Behavioral
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 3
States / cities: Glen Oaks, New York • Chapel Hill, North Carolina • Providence, Rhode Island

Conditions: Chronic Low-back Pain, Insomnia, Sleep
Interventions: No intervention is provided. We monitor natural recovery to full sleep.; Other
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 25 Years to 65 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Sleep Apnea, Obstructive
Interventions: Ramelteon or Placebo; Drug
Lead sponsor: Takeda; Industry
Eligibility: 21 Years to 64 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003
U.S. locations: 5
States / cities: Birmingham, Alabama • Palm Springs, California • Santa Monica, California + 2 more

Conditions: Sleep Apnea, Obstructive
Interventions: Not listed
Lead sponsor: Rakesh Sondekoppam Vijayashankar; Other
Eligibility: 18 Years to 85 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Insomnia
Interventions: CBT, MBSR; Behavioral
Lead sponsor: Cooper Norcross Health; Other
Eligibility: 18 Years and older
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2016
U.S. locations: 2
States / cities: Camden, New Jersey • Voorhees Township, New Jersey

Conditions: Obstructive Sleep Apnea
Interventions: Eszopiclone, Placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 64 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sleep Disordered Breathing, Alzheimer's Disease
Interventions: Continuous positive airway pressure (CPAP); Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 50 Years and older
Enrollment: 235 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 2
States / cities: New York, New York

Conditions: Chronic Fatigue Syndrome, Behavioral Therapy Targeted to Sleep Problems
Interventions: Cognitive Behavioral Therapy, Usual Care for Chronic Fatigue Syndrome (Active Control Group); Behavioral · Other
Lead sponsor: Duke University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Chronic Tonsillitis, Sleep Disordered Breathing
Interventions: Diet modification; Other
Lead sponsor: Georgetown University; Other
Eligibility: 3 Years to 12 Years
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Sleep Onset Insomnia
Interventions: NIghtingale (R) device for filtered white noise (Cambridge Sound Management, Waltham, MA); Device
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 21 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obstructive Sleep Apnea (OSA), Snoring, Sleep Quality
Interventions: Exercise; Other
Lead sponsor: Case Western Reserve University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Adolescent Behavior, Sleep Disturbance, Asthma in Children, Knowledge, Attitudes, Practice, Attitude, Habits
Interventions: PATH-S app; Behavioral
Lead sponsor: KDH Research & Communication; Industry
Eligibility: 14 Years to 17 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Atlanta, Georgia

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Turbinate Cauterization in Pediatric Patients With Nasal Obstruction

De-escalating Vital Sign Checks

Efficacy and Tolerability of Armodafinil in Adults With Excessive Sleepiness Associated With Shift Work Disorder

DAW2020 on OSA Endotypic Traits

Intraoperative Identification and Stimulation of the Glossopharyngeal Nerve

Polysomnography Study of GSK1838262 Extended Release Tablets Versus Placebo in RLS and Associated Sleep Disturbance

Patient-centered and Neurocognitive Outcomes With Acetazolamide for Sleep Apnea

Multi-center Clinical Trial of Limiting Resident Work Hours on ICU Patient Safety

Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

Pressure Relief Algorithm Eval

Audio-recorded Gut-Hypnotherapy for Sleep and Pain in Pediatric Abdominal Pain Disorders

Efficacy of Suvorexant in the Treatment of Hot Flash-associated Insomnia

Personalized Integrated Chronotherapy for Perinatal Depression

Partial Sleep Restriction in Chronic Low Back Pain: A Feasibility Study

Safety of Ramelteon in Subjects With Mild to Moderate Obstructive Sleep Apnea

Point-of-care-Ultrasound for Sleep Apnea

Insomnia Interventions in Cancer Survivors

The Effect of Eszopiclone on the Arousal Threshold in Sleep Apnea Syndrome

Sleep, Aging and Risk for Alzheimer's Disease

Behavioral Insomnia Therapy With Chronic Fatigue Syndrome

Outcomes of Post-operative Diet in Children Following Tonsillectomy and Adenoidectomy

Effect of Background Noise on Sleep Quality

The Impact of Technology in Obstructive Sleep Apnea Myofunctional Therapy

Personalized Approach To Habits - Sleep