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ClinicalTrials.gov public records Last synced Nov 13, 2026, 12:31 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 289–312 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Insomnia
Interventions: Telemedicine CBT-I, Conventional office-based CBT-I; Behavioral
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years and older
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Dysbiosis
Interventions: Creamy Richards 100% Peanuts! Creamy Natural Peanut Butter, Cadbury Milk Chocolate Spread; Other
Lead sponsor: Florida State University; Other
Eligibility: 6 Years to 13 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Sleep Apnea, Pediatric Sleep Apnea
Interventions: 3D printed NIV mask; Device
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 5 Years to 25 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Restless Legs Syndrome (RLS)
Interventions: Injectafer, Placebo; Drug · Other
Lead sponsor: American Regent, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 209 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 19
States / cities: Mobile, Alabama • National City, California • Rancho Mirage, California + 15 more

Conditions: Sleep Apnea Syndromes
Interventions: Video Teleconferencing Care, Usual Care; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: San Diego, California

Conditions: Head and Neck Cancer, Obstructive Sleep Apnea
Interventions: Nerve stimulation using nerve stimulation device and sterile wire electrode.; Device
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Pediatric Obstructive Sleep Apnea
Interventions: Psychomotor Vigilance Testing; Device
Lead sponsor: University of Arkansas; Other
Eligibility: 6 Years to 18 Years
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Delirium, Sleep Disorders, Circadian Rhythm
Interventions: Not listed
Lead sponsor: University of California, San Francisco; Other
Eligibility: 45 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Sleep Disordered Breathing, Sleep Apnea, Central
Interventions: Respironics BiPAP autoSV2, Respironics BiPAP autoSV3; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 5
States / cities: Tucson, Arizona • Little Rock, Arkansas • Portage, Michigan + 2 more

Conditions: Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms
Interventions: Solriamfetol 150 MG, Placebo; Drug
Lead sponsor: Axsome Therapeutics, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 508 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 40
States / cities: Tucson, Arizona • Bellflower, California • Chino, California + 33 more

Conditions: Chronic Insomnia
Interventions: Ramelteon, Placebo; Drug
Lead sponsor: Takeda; Industry
Eligibility: 18 Years and older
Enrollment: 451 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2006
U.S. locations: 19
States / cities: Birmingham, Alabama • Hot Springs, Arkansas • Los Angeles, California + 16 more

Conditions: Narcolepsy, Obstructive Sleep Apnea, Pregnant Women and Their Offspring
Interventions: Sunosi (solriamfetol), Other prescription wake-promoting medications or stimulants, No treatment; Drug · Other
Lead sponsor: Axsome Therapeutics, Inc.; Industry
Eligibility: Female only
Enrollment: 1,731 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2029
U.S. locations: 2
States / cities: Morrisville, North Carolina • Wilmington, North Carolina

Conditions: Sleep Fragmentation, Poor Quality Sleep, Nocturia, Nocturnal Enuresis
Interventions: Brief behavioral treatment of insomnia (BBTI), Information-only control (IC); Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 65 Years and older
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Intracerebral Hemorrhage
Interventions: NXY-059; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 64
States / cities: Birmingham, Alabama • Scottsdale, Arizona • Fort Smith, Arkansas + 61 more

Conditions: Obesity, Chronic Sleep Deprivation
Interventions: Increase sleep; Procedure
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 239 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2013
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder, Overweight and Obesity, Overweight, Overweight or Obesity, Diabetes Type 2, Diabetes Mellitus, Diabetes Mellitus, Type 2, Hypertension, Hyperlipidemias, Sleep Apnea, GERD, Gastroesophageal Reflux, Musculoskeletal Pain Disorder, Cancer
Interventions: Blood Collection, Urine Collection, Tissue Sample Collection; Diagnostic Test
Lead sponsor: Pichamol Jirapinyo, MD, MPH; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Psychological Stress, Anxiety, Emotional Stress, Autonomic Nervous System Dysfunction, Sleep Disturbance, Insomnia, Behavioral Health, Cognitive Fatigue, Occupational Stress, Financial Stress, Burnout Syndrome, Heart Rate Variability, Neurobehavioral Manifestations
Interventions: Wearable Physiologic Monitoring Platform; Device
Lead sponsor: Truway Health, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 2,500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: New York, New York

Conditions: Insomnia, Brain Injury
Interventions: Ramelteon, Placebo; Drug · Dietary Supplement
Lead sponsor: Kessler Foundation; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: West Orange, New Jersey

Conditions: Sleep Disorder
Interventions: Ramelteon, Placebo; Drug
Lead sponsor: Takeda; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005
U.S. locations: 13
States / cities: Hot Springs, Arkansas • Los Angeles, California • San Diego, California + 10 more

Conditions: Critically Ill
Interventions: Nocturnal coverage; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 1,609 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Insomnia
Interventions: CBTI-CS, Sleep Hygiene, CBTI-CS via Telehealth; Behavioral
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Leukemia, Anorexia, Anxiety, Depression, Dyspnea, Insomnia, Nausea, Pain
Interventions: Aromatherapy and Essential Oils, Placebo, Questionnaire Administration; Procedure · Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: Not listed
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Insomnia, Traumatic Brain Injury
Interventions: CBT-I, ABT-I; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Not listed
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Spinal Cord Injury, Sleep-disordered Breathing, Spinal Cord Disease, Multiple Sclerosis
Interventions: Best practices PAP + patient Education +ongoing Support and Training, Sleep Education; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Detroit, Michigan

Search by objective public record fields.

Non-inferiority Study of Telemedicine Versus Conventional CBT-I in Recently Hospitalized Patients With Insomnia

Effect of Peanut Butter on Gut and Metabolic Health

Use of a 3D Printer to Make Custom Sleep Masks for Positive Airway Pressure Treatment

Placebo-Controlled Study to Investigate the Efficacy & Safety of Injectafer in the Treatment of RLS

Using Telemedicine to Improve Veteran Sleep Apnea Care

Intraoperative Ansa Cervicalis Nerve (ACN) Stimulation

The Use of Psychomotor Vigilance Testing in the Assessment of Pediatric Obstructive Sleep Apnea

Study of Sleep and Delirium in the Intensive Care Unit (ICU)

Evaluation of Software Enhancements to the Respironics BiPAP Auto Servo Ventilation (AutoSV) Device

Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

Long-Term Efficacy and Safety of Ramelteon in Adults With Chronic Insomnia.

SUNOSI® (Solriamfetol) Pregnancy Registry

Impact of Behavioral Treatment of Insomnia on Nighttime Urine Production

Safety of NXY-059 for the Treatment of Patients Who Have Suffered From a Stroke

Chronic Sleep Deprivation as a Risk Factor for Metabolic Syndrome and Obesity

Biological Sample Repository for Gastrointestinal Disorders

NeuroFinance Human Stress Trial During Financial and Informational Volatility

Effect of Rozerem on Sleep Among People With Traumatic Brain Injury

Safety and Efficacy of Ramelteon in Healthy Subjects

24 Hour Intensivist Coverage in the Medical Intensive Care Unit

CBTI-CS: A Novel Cognitive-Behavioral Treatment for Insomnia in Cancer Survivors

Aromatherapy and Essential Oils in Improving Insomnia and Other Symptoms in Patients With Newly Diagnosed Acute Leukemia Undergoing Chemotherapy

Non-Pharmacological Treatments for Insomnia in Chronic Traumatic Brain Injury

Treatment of Sleep-disordered Breathing in Patients With SCI