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ClinicalTrials.gov public records Last synced Nov 14, 2026, 7:27 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 337–360 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Nocturia, Hypertension, Sleep Disturbance
Interventions: BBTI, PM antihypertensive dosing or Chronotherapy, AM antihypertensive dosing; Behavioral · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 65 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Obstructive Sleep Apnea
Interventions: oral appliance - A ; washout; oral appliance B, oral appliance - B; washout; oral appliance A; Device
Lead sponsor: Texas A&M University; Other
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Asthma, Obstructive Sleep Apnea
Interventions: FDA-Approved Treatment; Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 73 Years
Enrollment: 744 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Diabetes Mellitus, Type 2, Insulin Resistance, Glucose Intolerance, Sleep Disturbance, Overweight or Obesity, Insulin Sensitivity
Interventions: Resistance Exercise Timing; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 50 Years to 74 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Stress Disorders, Post-Traumatic, Combat Disorders, Ptsd, Nightmare, Nightmares, REM-Sleep Type, Nightmare Disorder With Associated Non-Sleep Disorder
Interventions: NightWare Therapeutic System; Device
Lead sponsor: NightWare; Industry
Eligibility: 22 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Obstructive Sleep Apnea
Interventions: Somnetics Transcend Auto, Respironics REMstar Auto with C-Flex; Device
Lead sponsor: Somnetics International, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 3
States / cities: Coon Rapids, Minnesota • Plymouth, Minnesota • San Antonio, Texas

Conditions: Sleep Deprivation, Insufficient Sleep Syndrome, Healthy
Interventions: PowerSleep Stim, PowerSleep Sham; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 21 Years to 50 Years
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 7
States / cities: Birmingham, Alabama • Little Rock, Arkansas • Lehigh Acres, Florida + 4 more

Conditions: Obstructive Sleep Apnea
Interventions: Maridebart cafraglutide, Placebo; Drug
Lead sponsor: Amgen; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 13
States / cities: Northridge, California • Rolling Hills Estates, California • Brandon, Florida + 10 more

Conditions: Restless Legs Syndrome
Interventions: Levetiracetam (Keppra); Drug
Lead sponsor: Sleep Health Centers; Other
Eligibility: 18 Years to 85 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Newton, Massachusetts

Conditions: Sleep Disturbance, Sleep Quality
Interventions: 2 mg THC + 2 mg CBN + 2 mg CBG + 10 mg CBD + 1 mg Melatonin, 10 mg THC + 5 mg CBN + 5 mg CBG + 20 mg CBD, 10 mg THC + 20 mg CBN + 5 mg CBG, Stay Asleep Placebo, Fast Asleep Placebo; Dietary Supplement
Lead sponsor: Cannabis Science Innovations, LLC; Industry
Eligibility: 21 Years to 55 Years
Enrollment: 332 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Sarasota, Florida

Conditions: Sleep Apnea
Interventions: Oxytocin; Drug
Lead sponsor: George Washington University; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Sleep Apnea Syndromes, Sleep Disorder, Sleep
Interventions: WatchPAT Intervention; Device
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 4 Years to 12 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Insomnia, Sleep Initiation and Maintenance Disorders, Alzheimer Disease
Interventions: modafinil; Drug
Lead sponsor: VA Palo Alto Health Care System; Federal
Eligibility: 50 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Brain Injuries, Traumatic, Sleeplessness
Interventions: Acupuncture, Sham Acupuncture; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 55 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 1
States / cities: Decatur, Georgia

Conditions: Sleep Disturbance, Mental Health Wellness 1
Interventions: The Calm App; Behavioral
Lead sponsor: Arizona State University; Other
Eligibility: 18 Years and older
Enrollment: 1,029 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Insomnia
Interventions: Not listed
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years to 55 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Sleep Disturbance
Interventions: Dietary Supplement: Speed Sleep, Placebo; Dietary Supplement
Lead sponsor: Bio Nature Health; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Sleep Apnea, Obstructive, Pregnancy, Hypertension
Interventions: WP200U home sleep study device; Diagnostic Test
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Durham, North Carolina

Conditions: Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy, Bursitis, Depression, Anxiety, Diabetes Mellitus, Esophageal Reflux, HIV Infections, Hyperlipidemia, Hypertension, Insomnia, Irritable Bowel Syndrome, Obesity, Osteoporosis (Senile), Shoulder Pain, Sinusitis, Symptomatic Menopause, Urinary Incontinence, Urinary Tract Infection, Vaginitis
Interventions: Health Information Prescription; Other
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 224 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Sleep Apnea, Sleep Disordered Breathing
Interventions: 14 days of placebo therapy, 14 days of CPAP therapy; Device
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years to 90 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2011
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Sleep Apnea
Interventions: Simultaneous assessment of sleep apnea by polysomnogram and wearable device; Diagnostic Test
Lead sponsor: Fitbit LLC; Industry
Eligibility: 18 Years and older
Enrollment: 303 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 5
States / cities: Jasper, Alabama • Burlingame, California • Irvine, California + 2 more

Conditions: Obstructive Sleep Apnea
Interventions: 129-Xe; Drug
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 3 Years to 18 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Knee Osteoarthritis, Insomnia
Interventions: Personalized exercise coaching, Cognitive behavioral therapy for Insomnia; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 50 Years and older
Enrollment: 288 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Drinking, Alcohol
Interventions: Advice, Self-monitoring, Feedback; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 25 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: New Haven, Connecticut

Search by objective public record fields.

Sleep, Hypertension, and Nocturia: a Multicomponent Approach for Comorbid Illnesses

Trial on Oral Appliance Design for Improving Upper Airway Function and Sleep Quality

Asthma and Obstructive Sleep Apnea (OSA)

The Acute T-Rex (Timing of Resistance Exercise) Study

Traumatic Nightmares Treated by NightWare (To Arouse Not Awaken)

Transcend Auto vs Commercially Available Device Clinical Evaluation for Treatment of Obstructive Sleep Apnea (OSA)

A Study of the Effectiveness and Efficacy of the PowerSleep Device

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy

A Double Blind Crossover Trial of Levetiracetam (Keppra®) and Placebo in the Treatment of Restless Legs Syndrome (RLS)

A Double-Blind, Randomized, Placebo-Controlled Study of the Safety and Effects of Various Cannabinoids on Sleep Quality

Oxytocin on HR in Sleep Apnea Patient

WatchPAT Device Validation Study Compared to Polysomnography

Modafinil Treatment for Sleep/Wake Disturbances in Older Adults

AcuSleep in Mild Traumatic Brain Injury (TBI)

Effects of Health and Wellness App on Employee Productivity

Magnetoencephalographic (MEG) Localization of Ramelteon's Effects on Brain Function and Cortical Arousal in Insomnia

A Study to Evaluate the Effects of the Speed Sleep Supplement on Sleep Quality and Quantity

OSA in Pregnant Women With Chronic HTN

Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow

Sleepiness and the Effects of CPAP on Salivary Cortisol and Alpha-Amylase Levels in Patients With Sleep Apnea

Validation of Software for Assessment of Sleep Apnea From Data Acquired by a Wearable Smartwatch

Improving Outcomes in Pediatric Obstructive Sleep Apnea With Computational Fluid Dynamics

Move and Snooze: Adding Insomnia Treatment to an Exercise Program to Improve Pain Outcomes in Older Adults With Knee Osteoarthritis

Multimodal Sleep Intervention Using Wearable Technology