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ClinicalTrials.gov public records Last synced Nov 14, 2026, 11:53 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 433–456 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Healthy Adult Male and Female Volunteers
Interventions: Low-frequency whole-body vibration mat; Device
Lead sponsor: Florida International University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Insomnia
Interventions: Ramelteon; Drug
Lead sponsor: Takeda; Industry
Eligibility: 6 Years to 50 Years
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 2
States / cities: Overland Park, Kansas • Kalamazoo, Michigan

Conditions: Fatigue, Sleep Disorders, Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Valeriana officinalis extract, placebo; Dietary Supplement · Other
Lead sponsor: Alliance for Clinical Trials in Oncology; Other
Eligibility: 18 Years and older
Enrollment: 227 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2010
U.S. locations: 33
States / cities: Aurora, Colorado • Boulder, Colorado • Colorado Springs, Colorado + 21 more

Conditions: Alpha-Thalassemia, Beta-Thalassemia, Amyloidosis, Amyotrophic Lateral Sclerosis, Creutzfeld-Jakob Disease, Cystic Fibrosis, Duchenne Muscular Dystrophy, Early-Onset Alzheimer Disease, Ehlers-Danlos Syndrome, Huntington Disease, Gaucher Disease, GM1 Gangliosidosis, Myasthenia Gravis, Pompe Disease, Sickle Cell Disease, Transthyretin Amyloid Cardiomyopathy, Rare Diseases
Interventions: Not listed
Lead sponsor: xCures; Industry
Eligibility: Not listed
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Los Altos, California

Conditions: Hypnotic Dependence Among Those With Insomnia
Interventions: 0% Hypnotic Medication Taper, 25% Hypnotic Medication Taper, 10% Hypnotic Medication Taper; Drug
Lead sponsor: National Jewish Health; Other
Eligibility: 21 Years and older
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: OSA, Obstructive Sleep Apnea
Interventions: Acetazolamide, Eszopiclone, Placebo, Venlafaxine; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 2
States / cities: La Jolla, California

Conditions: Sleep Apnea, Obstructive
Interventions: Telecommunications system, TLC-Control; Device · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Suvorexant, Placebo, Opioid Use Disorder
Interventions: Suvorexant, Placebo; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Sleep Apnea Obstructive (OSA)
Interventions: Wake training + TMR; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Insomnia
Interventions: Web-based CBT-I, Treatment as Usual; Behavioral · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older · Female only
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Stress Disorders, Post-Traumatic, Combat Disorders, Sleep Disorders
Interventions: prazosin hydrochloride, placebo; Drug
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 18 Years and older
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 2
States / cities: Seattle, Washington • Tacoma, Washington

Conditions: Obstructive Sleep Apnea, Malocclusion
Interventions: Homeoblock; Device
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Insomnia, Cognitive Dysfunction, Mild Cognitive Impairment, Sleep Initiation and Maintenance Disorders, Sleep Disorders, Intrinsic, Dyssomnias, Sleep Wake Disorders, Nervous System Diseases, Alzheimer Disease
Interventions: SHUTi OASIS, Patient Education; Behavioral · Other
Lead sponsor: University of Virginia; Other
Eligibility: 65 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Insomnia, Diabetes Mellitus, Type 2
Interventions: Insomnia Intervention, Information Control; Behavioral · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Sleep Apnea, Obstructive, Hypoxia, Hypercapnia, Sleep Disorders, Obesity, Hypertension, Coronary Artery Vasospasm, Right Ventricular Overload, Left Ventricular Function Systolic Dysfunction, Ventricular Hypertrophy
Interventions: Clinically prescribed CPAP therapy; Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 21 Years to 50 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Sleep Disorder
Interventions: Natrol; Drug
Lead sponsor: University of Nebraska; Other
Eligibility: 4 Years to 8 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Obstructive Sleep Apnea (OSA), Oral Applliance Therapy
Interventions: The study will assess the feasibility of incorporating the PLATO questionnaire into a dental sleep practice. The PLATO questionnaire was developed as a patient reported outcome measure; Other
Lead sponsor: Nevada Dental Sleep; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Henderson, Nevada

Conditions: Difficult Airway, Obstructive Sleep Apnea
Interventions: Ultrasound; Procedure
Lead sponsor: Vidya Raman; Other
Eligibility: 1 Month to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Apnea, Sleep
Interventions: Targeted infusion of remifentanil; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 70 Years
Enrollment: 77 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Psoriasis
Interventions: Not listed
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 64 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Sleep Initiation and Maintenance Disorders, Suicidal Ideation
Interventions: Digital Cognitive Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: MICHAEL A GRANDNER; Other
Eligibility: 55 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Occupational Health, Sleep, Fatigue, Nurse
Interventions: RN-SLEEP, Healthy Habit - Educational Control; Behavioral
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Obstructive Sleep Apnea (OSA)
Interventions: Case Management; Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Fontana, California

Conditions: Apnea, Sleep Disorders, Overweight and/or Obesity
Interventions: Berobenatide, Placebo; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years and older
Enrollment: 258 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 4
States / cities: Cullman, Alabama • Bradenton, Florida • Maplewood, Minnesota + 1 more

Search by objective public record fields.

Evaluating a Mat-Based Biometric Vibration System for Sleep and Daily Recovery

Pharmacokinetic and Safety of Ramelteon Between Adolescents With Insomnia and Healthy Adults

(Valerian) for Improving Sleep in Patients With Cancer Receiving Adjuvant Therapy

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

The Role of Tapering Pace and Selected Traits on Hypnotic Discontinuation

Combination Drug-Therapy for Patients With Untreated Obstructive Sleep Apnea

Telecommunications System in Sleep Apnea

Suvorexant as an Adjunct to Buprenorphine in Persons Who Use Fentanyl

Micromanaging Human Sleep Physiology to Treat Sleep Apnea and Other Disorders

Research on Expecting Moms and Sleep Therapy

Augmentation Trial of Prazosin for Post-Traumatic Stress Disorder (PTSD)

Changes in Upper Airway Anatomy, Quality of Life Measures, and Polysomnographic Parameters Using A Functional Dental Appliance

Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)

Diabetes Sleep Treatment Trial for Insomnia

"Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"

Melatonin CR for the Treatment of Impaired Sleep Maintenance in 4-8 Year Old Children With Autism Spectrum Disorders

Application of the Patient-reported Longitudinal Assessment Tool for OSA (PLATO) Questionnaire in Oral Appliance Therapy for Obstructive Sleep Apnea

Ultrasound to Predict a Pediatric Difficult Airway and Obstructive Sleep Apnea Syndrome in Children

Remifentanil in Adults With OSA

Prevalence of Sleep Disturbances in Psoriasis

Addressing Nocturnal Sleep/Wake Effects on Risk of Suicide in Older Adults

Using Cognitive-Behavioral Change and Mobile Technology to Improve RN Sleep and Fatigue

CPAP Population Management

A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Do Not Use a Breathing Machine (PAP) (VESPER-OSA 2)