Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 12, 2026, 12:26 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 2,612 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: REM Sleep Behavior Disorder, Pre-motor Parkinson Disease, Symptomatic Parkinson Disease
Interventions: Carvedilol; Drug
Lead sponsor: Michele Tagliati, MD; Other
Eligibility: 50 Years to 85 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Sleep Disturbance, Mental Health Issue
Interventions: Herbal Pillows; Other
Lead sponsor: Duquesne University; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Back Pain, Insomnia
Interventions: Active Mattress Cover, Placebo Mattress Cover; Device
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Orange, California

Conditions: Treatment Resistant Depression, Insomnia
Interventions: Brief Behavioral Treatment for Insomnia; Behavioral
Lead sponsor: VA Pittsburgh Healthcare System; Federal
Eligibility: 60 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Sleep Deprivation, Sleep Fragmentation
Interventions: Not listed
Lead sponsor: University of Chicago; Other
Eligibility: 50 Years and older
Enrollment: 771 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2020
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Restless Legs Syndrome
Interventions: Bupropion, Placebo; Drug
Lead sponsor: East Tennessee State University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Johnson City, Tennessee

Conditions: Sleep, Inadequate, Sleep
Interventions: Yoga-based bedtime routine; Behavioral
Lead sponsor: Emily Guseman; Other
Eligibility: 2 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Athens, Ohio

Conditions: Migraine, Headache, Multiple Sclerosis, Insomnia
Interventions: Smartphone-Based Progressive Muscle Relaxation Therapy (PMR), Monitored Usual Care (MUC); Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 80 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Cold-water Immersion, High Heat Sauna, Combination of Cold-water Immersion and High Heat Sauna
Interventions: Cold Water Immersion, High Heat Sauna; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 30 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Acute Decompensated Heart Failure, Sleep Disordered Breathing
Interventions: MV ASV, Optimized Medical Treatment; Device · Drug
Lead sponsor: ResMed; Industry
Eligibility: 21 Years and older
Enrollment: 126 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 14
States / cities: Huntsville, Alabama • Los Angeles, California • Denver, Colorado + 11 more

Conditions: Obstructive Sleep Apnea
Interventions: One handed mask airway, switch to two hands, Two handed mask airway + jaw thrust, Two handed mask airway, switch to one hand; Procedure
Lead sponsor: Nemours Children's Clinic; Other
Eligibility: 1 Year to 8 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Wilmington, Delaware

Conditions: OSA
Interventions: AD109, Placebo; Drug
Lead sponsor: Apnimed; Industry
Eligibility: 18 Years and older
Enrollment: 660 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 64
States / cities: Birmingham, Alabama • Chandler, Arizona • Little Rock, Arkansas + 59 more

Conditions: Obstructive Sleep Apnea, Cognitive Decline
Interventions: Positive airway pressure, Oral appliance therapy, Positional therapy; Device
Lead sponsor: California Pacific Medical Center Research Institute; Other
Eligibility: 55 Years to 85 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 4
States / cities: Tucson, Arizona • New York, New York • Pittsburgh, Pennsylvania

Conditions: Sleep Apnea, Sleep Disorder
Interventions: TatchSleep; Device
Lead sponsor: Wesper Inc; Industry
Eligibility: 18 Years to 120 Years
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Substance Use Disorders, Insomnia
Interventions: Cognitive Behavioral Therapy for Insomnia (CBT-I); Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Sleep Apnea, Metabolic Syndrome
Interventions: Not listed
Lead sponsor: Tufts Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 258 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tonsillectomy Postoperative Adverse Events
Interventions: Not listed
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: Up to 17 Years
Enrollment: 2,400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Fatigue, Sleep Disorders, Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Valeriana officinalis extract, placebo; Dietary Supplement · Other
Lead sponsor: Alliance for Clinical Trials in Oncology; Other
Eligibility: 18 Years and older
Enrollment: 227 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2010
U.S. locations: 33
States / cities: Aurora, Colorado • Boulder, Colorado • Colorado Springs, Colorado + 21 more

Conditions: Transient Insomnia
Interventions: SM-1, D+Z, D+L, Placebo; Drug
Lead sponsor: Sequential Medicine Ltd; Industry
Eligibility: 18 Years and older
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 2
States / cities: Atlanta, Georgia • New York, New York

Conditions: Chronic Insomnia
Interventions: Implementation Strategy: Foundational Arm, Implementation Strategy: REACH arm; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 60 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Sleep Apnea, Obstructive
Interventions: Not listed
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Idiopathic Hypersomnia, Excessive Daytime Sleepiness
Interventions: Pitolisant; Drug
Lead sponsor: Harmony Biosciences Management, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 119 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 32
States / cities: Los Angeles, California • San Ramon, California • Brandon, Florida + 29 more

Conditions: Down Syndrome, Obstructive Sleep Apnea
Interventions: Family-informed intervention, Standard Clinical Care; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 6 Years to 18 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 3
States / cities: Miami, Florida • Cincinnati, Ohio • Philadelphia, Pennsylvania

Conditions: Sleep Apnea
Interventions: Acceptance and the Behavioral Changes to Treat Sleep Apnea (ACB-SA), Non-directive sleep apnea education control; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older · Female only
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Sepulveda, California

Search by objective public record fields.

Adrenergic Blockers for Cardiac Changes in Early Parkinson's Disease (Protocol 53136)

Sweet Scents to Sweet Dreams

Trial on the Effect of Optically Modified Fiber Mattress Covers on Sleep Disturbances in Patients With Chronic Back Pain

Treatment Resistant Depression and Insomnia in Older Veterans

Understanding Sleep in Hospitalized Older Patients

Bupropion and Restless Legs Syndrome

Using Yoga to Reduce Chaos and Improve Preschooler Sleep

RELAXaHEAD for Headache Patients (Phase II)

Thermodynamic Exposure and Sleep in Military Cadets

Cardiovascular Improvements With MV ASV Therapy in Heart Failure

Mask Study: One-handed vs. Two Handed Technique in Children

Parallel Arm Trial of AD109 and Placebo With Patients With OSA (LunAIRo)

The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

TatchSleep as a Tool to Aid in Sleep Apnea Analysis

Cognitive Behavioral Therapy for Insomnia in Substance Use Disorders

Improving the STOP-Bang Screening Questionnaire for Patients With Sleep Apnea

Factors Predictive of Adverse Postoperative Outcomes in Children Undergoing Tonsillectomy

(Valerian) for Improving Sleep in Patients With Cancer Receiving Adjuvant Therapy

SM-1 vs 2 Comparators and Placebo in Participants With a History of Transient Insomnia.

Implementing Cognitive Behavioral Therapy for Insomnia (SWELL): Function QUERI 3.0

Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep

A Long-Term Safety and Effectiveness Study to Evaluate Pitolisant in Adult Patients With Idiopathic Hypersomnia

Positive Airway Pressure (PAP) for Children With Down Syndrome (DS) and Obstructive Sleep Apnea Syndrome (OSAS)

Treating Sleep Apnea in Women Veterans