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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:32 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 793–816 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Xerostomia
Interventions: NeutraSal, Placebo Comparator; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 84 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Sleep Disorder, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer
Interventions: Brief Behavioral Therapy, Telephone-Based Intervention, Educational Intervention; Behavioral · Other
Lead sponsor: Gary Morrow; Other
Eligibility: 21 Years and older · Female only
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 6
States / cities: Stanford, California • Decatur, Illinois • Wichita, Kansas + 3 more

Conditions: Obstructive Sleep Apnea
Interventions: HGNS Treatment; Device
Lead sponsor: Apnex Medical, Inc.; Industry
Eligibility: 21 Years to 70 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 4
States / cities: San Francisco, California • Indianapolis, Indiana • Minneapolis, Minnesota + 1 more

Conditions: Obstructive Sleep Apnea
Interventions: Dexmedetomidine, Placebo; Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis (Pfapa), Obstructive Sleep Apnea, Tonsillitis, Tonsil Disorder, Sleep Disordered Breathing
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 1 Month to 99 Years
Enrollment: 1,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2038
U.S. locations: 3
States / cities: Washington D.C., District of Columbia • Indianapolis, Indiana • Bethesda, Maryland

Conditions: Sleep Initiation and Maintenance Disorders
Interventions: GW679769, Placebo; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 64 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 7
States / cities: San Diego, California • Atlanta, Georgia • New York, New York + 4 more

Conditions: Narcolepsy
Interventions: Samelisant, Placebo; Drug
Lead sponsor: Suven Life Sciences Limited; Industry
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Sleep Apnea, Obstructive
Interventions: Propofol sedation; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2035
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Sleep, Sleep Disturbance
Interventions: Elemind Neuromodulation (ENMod); Device
Lead sponsor: Elemind Technologies, Inc.; Industry
Eligibility: 21 Years to 55 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Sleep Deprivation
Interventions: Controlled Dietary Intervention; Drug
Lead sponsor: St. Vincent's Medical Center; Other
Eligibility: 25 Years to 40 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2005
U.S. locations: 1
States / cities: New York, New York

Conditions: Old Adults, Sleep Quality, Kava, Mobility Impairment, Physical Activity and Stress, Physical Impairment, Sedentary Lifestyle in Patients Over 70
Interventions: AB-free kava, Placebo; Drug · Other
Lead sponsor: University of Florida; Other
Eligibility: 70 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: Gainesville, Florida

Conditions: Sleep Apnea
Interventions: Acetazolamide; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: RLS
Interventions: HORIZANT 300 mg, HORIZANT 600 mg, Placebo; Drug
Lead sponsor: XenoPort, Inc.; Industry
Eligibility: 13 Years to 17 Years
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2023
U.S. locations: 12
States / cities: Redwood City, California • Gulf Breeze, Florida • Winter Park, Florida + 9 more

Conditions: Type 2 Diabetes, Obesity, Overweight, Obstructive Sleep Apnea
Interventions: Retatrutide, Placebo; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years and older
Enrollment: 1,152 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 40
States / cities: Anniston, Alabama • Cullman, Alabama • Little Rock, Arkansas + 36 more

Conditions: Obstructive Sleep Apnea
Interventions: Not listed
Lead sponsor: Memorial Health System; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Colorado Springs, Colorado

Conditions: Major Depressive Disorder (MDD)
Interventions: Cognitive Behavioral Therapy for Insomnia, PET Scan with [11C]ABP688; Behavioral · Drug
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Generalized Anxiety Disorder, Sleep Disturbances
Interventions: Not listed
Lead sponsor: Children's National Research Institute; Other
Eligibility: 7 Years to 11 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2009
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Excessive Daytime Sleepiness, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS)
Interventions: Armodafinil; Drug
Lead sponsor: Cephalon; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 247 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2006
U.S. locations: 43
States / cities: Birmingham, Alabama • Tuscaloosa, Alabama • Phoenix, Arizona + 37 more

Conditions: Heart Failure, Sleep Apnea, Obstructive
Interventions: Adaptive Servo-Ventilation; Device
Lead sponsor: Veterans Medical Research Foundation; Other
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: San Diego, California

Conditions: Adult Nocturnal Enuresis, Urinary Incontinence (UI)
Interventions: PureWick System, Hollister Female Urinary Pouch External Collection Device; Device
Lead sponsor: C. R. Bard; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 171 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 15
States / cities: Guntersville, Alabama • Chandler, Arizona • Eagle Rock, California + 12 more

Conditions: Apnea, Sleep
Interventions: RFA treatment; Device
Lead sponsor: Olympus Surgical Technologies Europe; Industry
Eligibility: 22 Years and older
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 6
States / cities: Beverly Hills, California • Greenwood Village, Colorado • Atlanta, Georgia + 3 more

Conditions: Opioids, Obstructive Sleep Apnea (OSA)
Interventions: Morphine p.o., Placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Stress Disorders, Post-Traumatic, Sleep Disorders
Interventions: prazosin, paroxetine, Placebo; Drug
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 18 Years to 50 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Fort Lewis, Washington

Conditions: REM Sleep Behavior Disorder (iRBD)
Interventions: Syn-One Test; Diagnostic Test
Lead sponsor: CND Life Sciences; Other
Eligibility: 18 Years to 85 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 8
States / cities: Chandler, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 5 more

Search by objective public record fields.

NeutraSal Treatment for Xerostomia in OSAS Patients Using CPAP Therapy

Brief Behavioral Therapy in Improving Sleep Disorders in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy

US Clinical Study of the Apnex Medical Hypoglossal Nerve Stimulation (HGNS) System to Treat Obstructive Sleep Apnea

Dex as Analgesic Adjuvant in OSA Patients

Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders

A Study to Evaluate the Effects of GW679769 on Sleep and Cognitive Function in Subjects With Primary Insomnia

A Phase 3 Study to Evaluate the Efficacy and Safety of Samelisant in Patients With Narcolepsy (AWAKE)

Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea

Sounds Locked to ElectroEncephalogram Phase For the Acceleration of Sleep Onset Time

A Change in Diet May Decrease the Negative Consequences of Chronic Sleep Deprivation

Kava Aging and Mobility Study

A Single-center Pilot Study Evaluating the Immediate Effects of Low-dose Acetazolamide on Respiratory Control in Subjects With Treatment Emergent Sleep Disordered Breathing

An Efficacy and Safety Evaluation of HORIZANT in Adolescents With Moderate-to-Severe Primary RLS

A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight

Pre and Post Orthopedic Surgery Sleep and Cardiac Testing (PROSPECT)

The Role of mGluR5 in CBT-I

Mechanisms of Sleep Disturbance in Children With Generalized Anxiety Disorder (GAD)

Study to Assess Patient Reported Outcomes With Armodafinil Treatment for Excessive Sleepiness in Adults With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome

Adaptive Servo-Ventilation In Acute Heart Failure Patients Protecting the Heart and Kidneys

This Study Will Collect Clinical and Patient Reported Experience Data From Participants Requiring Urine Output Management Overnight in the Home Setting.

Radiofrequency Ablation for Multi-level Obstructive Sleep Apnea: A Single-arm, Multicenter Study

Impacts of Opioids on Respiratory Drive During Sleep

Prazosin vs Paroxetine in Combat Stress-Related Post-Traumatic Stress Disorder (PTSD) Nightmares & Sleep Disturbance

The Syn-Sleep Study