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ClinicalTrials.gov public records Last synced Nov 12, 2026, 8:19 AM EST

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Showing 97–120 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Insomnia Disorder, Mild Traumatic Brain Injury
Interventions: Sleep MAPP Care Pathway; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 900 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2029
U.S. locations: 2
States / cities: Aurora, Colorado • Tampa, Florida

Conditions: Sleep Deprivation, Insufficient Sleep Syndrome, Sleep Wake Disorders
Interventions: Increased sleep duration; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 35 Years
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Restless Legs Syndrome
Interventions: Levetiracetam (Keppra); Drug
Lead sponsor: Sleep Health Centers; Other
Eligibility: 18 Years to 85 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Newton, Massachusetts

Conditions: Sleep Disorders, Circadian Rhythm, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder, Advanced Sleep Phase Syndrome (ASPS), Delayed Sleep Phase Syndrome, Sleep Wake Disorders, Sleep Disorder
Interventions: dim light melatonin onset (DLMO); Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 50 participants
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: Ramelteon and Placebo; Drug
Lead sponsor: Takeda; Industry
Eligibility: 40 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006
U.S. locations: 8
States / cities: Birmingham, Alabama • Los Angeles, California • Santa Monica, California + 5 more

Conditions: Sleep Quality, Sleep Health
Interventions: Sleep Supplement, Placebo; Dietary Supplement
Lead sponsor: 4Life Research, LLC; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Sandy City, Utah

Conditions: Chronic Cough, OSA
Interventions: Straight CPAP, Sham CPAP; Device
Lead sponsor: Krishna M. Sundar; Other
Eligibility: 18 Years to 80 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Nausea, Gastroparesis, Stress, Anxiety, Hyperarousal, Quality of Life, Vomiting, Heart Rate Variability
Interventions: Cereset Research; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Obstructive Sleep Apnea
Interventions: Auto-titrating mandibular positioner test; Device
Lead sponsor: Zephyr Sleep Technologies; Industry
Eligibility: 18 Years and older
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Bellevue, Washington

Conditions: Hypersomnolence
Interventions: NextSense EEG-enabled earbuds, Ellcie Healthy eyeglasses, Drug Holiday; Device · Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Obesity, Overweight, Obstructive Sleep Apnoea
Interventions: NNC0487-0111, Placebo (matched to NNC0487-0111); Drug
Lead sponsor: Novo Nordisk A/S; Industry
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 20
States / cities: Gilbert, Arizona • Bradenton, Florida • Naples, Florida + 16 more

Conditions: Sleep Apnea Syndromes, Inflammation
Interventions: Weight Loss Program, CPAP therapy; Behavioral · Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 80 Years
Enrollment: 181 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2013
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Myotonic Dystrophy 1, Excessive Daytime Sleepiness
Interventions: Pitolisant Oral Tablet, Placebo oral tablet; Drug
Lead sponsor: Harmony Biosciences Management, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 11
States / cities: Irvine, California • Aurora, Colorado • Tampa, Florida + 8 more

Conditions: Insomnia
Interventions: zolpidem tartrate; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 21 Years to 64 Years
Enrollment: 372 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Bridgewater, New Jersey

Conditions: Obstructive Sleep Apnea, Neurocognitive Disorders
Interventions: Brain Imaging, Cognitive testing, Blood Biomarkers; Diagnostic Test
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 40 Years to 75 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Hypertrophic Cardiomyopathy
Interventions: Not listed
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 290 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2024
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Sleep Disordered Breathing, Cheyne-Stokes Respiration, Sleep Apnea
Interventions: Phrenic stimulation device; Device
Lead sponsor: Respicardia, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2013
U.S. locations: 3
States / cities: Minneapolis, Minnesota • Cincinnati, Ohio • Columbus, Ohio

Conditions: Postpoliomyelitis Syndrome
Interventions: Modafinil; Drug
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Sleep, Inadequate, Sleep
Interventions: Yoga-based bedtime routine; Behavioral
Lead sponsor: Emily Guseman; Other
Eligibility: 2 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Athens, Ohio

Conditions: Sleep Initiation and Maintenance Disorders, Insomnia
Interventions: Eplivanserin, placebo; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years and older
Enrollment: 967 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Bridgewater, New Jersey

Conditions: Obstructive Sleep Apnea, Atrial Fibrillation
Interventions: Cardiac Ablation for Atrial Fibrillation; Procedure
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Atrial Fibrillation, Arrhythmia, Stroke, Cardiovascular
Interventions: The Lifestar Act III; Device
Lead sponsor: University of Miami; Other
Eligibility: 40 Years to 85 Years
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Physician Well-being, Cognitive Function, Diet Modification, Diet Habit, Shift-Work Related Sleep Disturbance, Sleep Deprivation
Interventions: Dietary Modification; Other
Lead sponsor: Stanford University; Other
Eligibility: 21 Years and older
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Stanford, California

Conditions: Post-Traumatic Stress Disorders
Interventions: Eszopiclone; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 64 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Boston, Massachusetts

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Sleep MAPP in the Polytrauma/TBI System of Care

Biomarkers of Increased Free Living Sleep Time

A Double Blind Crossover Trial of Levetiracetam (Keppra®) and Placebo in the Treatment of Restless Legs Syndrome (RLS)

Validation of Circadian Biomarkers in Patients With Sleep Disorders

Safety of Ramelteon in Subjects With Chronic Obstructive Pulmonary Disease

Clinical Study to Assess a Dietary Supplement on Sleep Health and Quality

Sham CPAP vs. Straight CPAP for Chronic Cough

Cereset Research For Chronic Nausea

Workflow Validation of an In-home Auto-titrating Mandibular Positioner

Sleep/Wake State Assessment with Non-invasive Earbuds

AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

The Effects of Obesity and Obstructive Sleep Apnea on Inflammation and Heart Disease

Safety and Efficacy of Pitolisant on Excessive Daytime Sleepiness and Other Non-Muscular Symptoms in Patients With Myotonic Dystrophy Type 1

Ambien CR vs. Placebo For Treatment Of Insomnia Associated With Anxiety When Used Concomitantly With Escitalopram (Lexapro)

Postoperative Neurocognitive Disorders

Sleep Apnea and Hypertrophic Cardiomyopathy (HCM)

Feasibility Study to Determine the Effects of Phrenic Nerve Stimulation in Patients With Periodic Breathing

Modafinil to Treat Fatigue in Post-Polio Syndrome

Using Yoga to Reduce Chaos and Improve Preschooler Sleep

Efficacy and Safety of Eplivanserin Treatment for Sleep Maintenance Insomnia

Effects of PAP on Afib Recurrence Risk After Catheter Ablation in OSA Patients

Arrhythmia Detection In Obstructive Sleep Apnea (ADIOS)

Performance Nutrition for Residents and Fellows

Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder