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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:13 PM EST

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Showing 1417–1440 of 2,615 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep-Wake Disorders Clear all
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

The Role of Dopamine Metabolism in the Antidepressant Effects of Sleep Deprivation and Sertraline in Depressed Patients

NCT00581009
View directory record Official record
Conditions
Major Depressive Disorder, Bipolar Disorder
Interventions
chronobiological augmentation, sertraline, lithium, one night of sleep deprivation and two FDG PET scans
Other · Drug · Radiation
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 75 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2011
U.S. locations
2
States / cities
Irvine, California • La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 17, 2024 · Synced Nov 15, 2026, 2:13 PM EST
Completed Not applicable Interventional Results available

Randomized, Controlled, Double Blind Trial of Eszopiclone for Insomnia Associated With Schizophrenia

NCT00645944
View directory record Official record
Conditions
Insomnia, Schizophrenia, Schizoaffective Disorder, Sleep Disorders
Interventions
Eszopiclone, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 64 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 16, 2015 · Synced Nov 15, 2026, 2:13 PM EST
Completed Phase 4 Interventional Results available

Efficacy of Suvorexant to Treat Insomnia Related to Bipolar Disorder

NCT02527564
View directory record Official record
Conditions
Insomnia, Bipolar Disorder
Interventions
Suvorexant, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Nov 15, 2026, 2:13 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Repeated Operational Stress and Limited Recovery on Resilience Capacity

NCT06784544
View directory record Official record
Conditions
Sleep, Inadequate, Energy Deficit, Iron Absorption, High Physical Activity
Interventions
Operational Stressors
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
17 Years to 39 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 9, 2026 · Synced Nov 15, 2026, 2:13 PM EST
Terminated Phase 3 Interventional Results available

A Study to Evaluate the Safety, Tolerability, and Efficacy of SAGE-217 Compared to Placebo in Adult Participants With Comorbid Major Depressive Disorder (MDD) and Insomnia

NCT03771664
View directory record Official record
Conditions
Major Depressive Disorder, Insomnia
Interventions
SAGE-217, Placebo
Drug
Lead sponsor
Biogen
Industry
Eligibility
18 Years to 64 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
28
States / cities
Little Rock, Arkansas • Rogers, Arkansas • Garden Grove, California + 24 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Nov 15, 2026, 2:13 PM EST
Completed Not applicable Interventional

Study Comparing In-laboratory Polysomnography Electrocardiogram (PSG ECG) to Simultaneously Recorded In-laboratory ECG on the CPC M1 Device

NCT01234077
View directory record Official record
Conditions
Sleep Disorder
Interventions
CPC M1
Device
Lead sponsor
National Jewish Health
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 19, 2021 · Synced Nov 15, 2026, 2:13 PM EST
Recruiting Not applicable Interventional

RCT of a Weighted Blanket to Reduce Pain in Veterans With Chronic Pain

NCT05963607
View directory record Official record
Conditions
Chronic Pain, Sleep Disturbance
Interventions
Weighted blanket
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
San Diego, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Nov 15, 2026, 2:13 PM EST
Completed Not applicable Interventional Results available

Blue Wavelength Light-blocking Glasses in ADHD-Insomnia

NCT01557595
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Delayed Sleep Phase Type Circadian Rhythm Sleep Disorder
Interventions
Polarized glasses designed to filter out blue light
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 13, 2017 · Synced Nov 15, 2026, 2:13 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness of Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep - Clinical Trial

NCT06631209
View directory record Official record
Conditions
Insomnia
Interventions
Transcranial Magnetic Stimulation (TMS), Sham
Device · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 60 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Nov 15, 2026, 2:13 PM EST
Completed Phase 1 Interventional Results available

Tailored Intervention to Promote Positive Airway Pressure Adherence

NCT01454830
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Patient Compliance
Interventions
Tailored, Usual care
Behavioral · Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 23, 2016 · Synced Nov 15, 2026, 2:13 PM EST
Completed Phase 4 Interventional

Cognitive-Behavior Therapy for Insomnia

NCT00869934
View directory record Official record
Conditions
Chronic Insomnia
Interventions
Cognitive-Behavior Therapy, Behavior Therapy, Cognitive Therapy
Other
Lead sponsor
Laval University
Other
Eligibility
25 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2013 · Synced Nov 15, 2026, 2:13 PM EST
Completed Not applicable Interventional Results available

Pilairo Lab Market Research

NCT01824979
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP mask ( Pilairo), Other CPAP mask
Device · Procedure
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Burlingame, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2018 · Synced Nov 15, 2026, 2:13 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Using Yoga to Reduce Chaos and Improve Preschooler Sleep

NCT06549868
View directory record Official record
Conditions
Sleep, Inadequate, Sleep
Interventions
Yoga-based bedtime routine
Behavioral
Lead sponsor
Emily Guseman
Other
Eligibility
2 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 12, 2024 · Synced Nov 15, 2026, 2:13 PM EST
Terminated Not applicable Interventional Results available

Remote Monitoring in Obstructive Sleep Apnea

NCT01678560
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Monitoring every 3 months by face-to-face visits, Frequent remote monitoring
Device
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
18 Years to 90 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 11, 2019 · Synced Nov 15, 2026, 2:13 PM EST
Withdrawn Not applicable Interventional

Reports on Sleep Quality and Thermoregulation Among Veterans

NCT04236661
View directory record Official record
Conditions
Sleep Disturbance
Interventions
chilipad
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 7, 2020 · Synced Nov 15, 2026, 2:13 PM EST
Completed No phase listed Observational

Natural History Study of Smith-Magenis Syndrome

NCT00013559
View directory record Official record
Conditions
Smith-Magenis Syndrome (SMS)
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
1 Month to 115 Years
Enrollment
593 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Nov 15, 2026, 2:13 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Reducing Caregiver Stress and Sleep Disturbances in Patients With Progressive Dementia

NCT00178568
View directory record Official record
Conditions
Sleep Disorders
Interventions
Stress Management and Healthy Sleep Practices
Behavioral
Lead sponsor
Kathy Kennedy
Other
Eligibility
60 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2015 · Synced Nov 15, 2026, 2:13 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Consequences of Conjugal Bereavement in Adults

NCT00001659
View directory record Official record
Conditions
Bereavement, Depressive Disorder, Immunologic Disease, Mental Disorder, Sleep Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Nov 15, 2026, 2:13 PM EST
Completed Not applicable Interventional Results available

Digital Cognitive-Behavioral Therapy for Insomnia in Spanish Speaking Latinas/os (Dormir Mejor Study)

NCT05353296
View directory record Official record
Conditions
Insomnia
Interventions
Digital cognitive behavioral therapy for insomnia (CBT-I) program, Minimally Enhanced Usual Care (mEUC), Somryst (culturally adapted)
Behavioral · Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 1, 2025 · Synced Nov 15, 2026, 2:13 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Radicle ACES: A Study of Commercially Available CBD Used in the Real-world Setting

NCT05003882
View directory record Official record
Conditions
Pain, Sleep Disturbance, Anxiety
Interventions
Commercially available, orally ingestible CBD product
Other
Lead sponsor
Radicle Science
Industry
Eligibility
21 Years and older
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Encinitas, California
Source: ClinicalTrials.gov public record
Updated Mar 28, 2022 · Synced Nov 15, 2026, 2:13 PM EST
Completed No phase listed Observational Results available

Post Approval Study of the remedē System

NCT03425188
View directory record Official record
Conditions
Central Sleep Apnea
Interventions
Not listed
Lead sponsor
Respicardia, Inc.
Industry
Eligibility
21 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
16
States / cities
Los Angeles, California • Jacksonville, Florida • Downers Grove, Illinois + 13 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Nov 15, 2026, 2:13 PM EST
Recruiting Phase 2 Interventional

A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy

NCT07493265
View directory record Official record
Conditions
Narcolepsy
Interventions
E2086, Placebo
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
17
States / cities
Santa Ana, California • Brandon, Florida • Medley, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Nov 15, 2026, 2:13 PM EST
Active, not recruiting Phase 2 Interventional

Terazosin and Parkinson's Disease Extension Study

NCT05109364
View directory record Official record
Conditions
Symptomatic Parkinson Disease, REM Sleep Behavior Disorder, Pre-motor Parkinson's Disease
Interventions
Terazosin therapy
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
50 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Nov 15, 2026, 2:13 PM EST
Completed Phase 3 Interventional Results available

Apnea Positive Pressure Long-Term Efficacy Study

NCT00051363
View directory record Official record
Conditions
Lung Diseases, Sleep Apnea Syndromes, Sleep
Interventions
Active CPAP, Sham CPAP
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
1,105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
5
States / cities
Tucson, Arizona • Palo Alto, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Nov 15, 2026, 2:13 PM EST