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ClinicalTrials.gov public records Last synced Nov 6, 2026, 5:26 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 265–288 of 797 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Smoker Clear all

Conditions: Nicotine, Nicotine Vaping, E-cigarette Use
Interventions: Vaping study EC A, Vaping study EC B, Vaping study EC C, Vaping study EC D, Vaping study EC E, Vaping study EC F, Vaping study EC G, Vaping study EC H, Vaping study EC I, Vaping study EC J; Behavioral
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 21 Years to 50 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Cigarette Smoker, Tobacco Use Disorder
Interventions: Behavioral Intervention, Laboratory Biomarker Analysis, Nicotine Patch, Questionnaire Administration, Smoking Cessation Intervention; Behavioral · Other · Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 85 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Smoking, Tobacco, Smoking (Tobacco) Addiction
Interventions: Cigarette 1, Cigarette 2, Patch 1, Patch 2; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 21 Years and older
Enrollment: 221 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Smoking Cessation
Interventions: UP-ST Therapy, Standard Therapy, Nicotine Patch; Behavioral · Device
Lead sponsor: University of Houston; Other
Eligibility: 18 Years to 65 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Lung Cancer Prevention
Interventions: green tea, Polyphenon E, placebo; Dietary Supplement · Drug · Other
Lead sponsor: Sherry Chow; Other
Eligibility: 40 Years to 80 Years
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2004
U.S. locations: 3
States / cities: Tucson, Arizona

Conditions: Smoking Behaviors
Interventions: Control Intervention, Experimental Intervention; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Smoking Cessation
Interventions: Cytisinicline, Placebo, Behavioral support; Drug · Behavioral
Lead sponsor: Achieve Life Sciences; Industry
Eligibility: 18 Years and older
Enrollment: 810 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 17
States / cities: Mobile, Alabama • Phoenix, Arizona • Coral Gables, Florida + 14 more

Conditions: Tobacco Dependence
Interventions: Placebo, Nicotine; Drug
Lead sponsor: McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 257 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 19
States / cities: Muscle Shoals, Alabama • Oceanside, California • Griffin, Georgia + 16 more

Conditions: Lung Cancer
Interventions: chest x-ray with or without CAD, lose dose CT scan; Device
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 40 Years to 75 Years
Enrollment: 1,424 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Smoking Cessation
Interventions: HealthyCells; Behavioral
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Marijuana Abuse
Interventions: Yohimbine; Drug
Lead sponsor: Wayne State University; Other
Eligibility: 21 Years to 55 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Smoking Cessation, Family, Health Behavior
Interventions: Quit Smoking for a Healthy Family, Healthy Living; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 680 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 3
States / cities: San Francisco, California • San Jose, California

Conditions: Lung Cancer, Precancerous Condition
Interventions: Not listed
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 45 Years and older
Enrollment: 112 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2000 – 2009
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Tobacco Smoking
Interventions: menthol ban in cigarettes only, total menthol ban; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 21 Years and older
Enrollment: 151 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Lung Cancer
Interventions: Smoking cessation intervention, Counseling intervention, Nicotine patch; Behavioral · Other · Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 21 Years to 65 Years
Enrollment: 462 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2016
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Smoking, Smoking Behaviors, Smoking Cessation, Stress Reaction
Interventions: Not listed
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 75 Years · Male only
Enrollment: 95 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 2
States / cities: Los Angeles, California • Charleston, South Carolina

Conditions: Cardiopulmonary Disease, Smoking Cessation, Inpatient
Interventions: Enhanced Usual Care (EUC), Nurse Practitioner Tobacco Treatment Team (NPT3); Other
Lead sponsor: Baystate Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 424 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Springfield, Massachusetts

Conditions: Healthy Subjects
Interventions: GW876008; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2006
U.S. locations: 1
States / cities: Willingboro, New Jersey

Conditions: Smoking, Cigarette
Interventions: Inhaled Loxapine 10 mg; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 20 Years to 50 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009
U.S. locations: 1
States / cities: Evansville, Indiana

Conditions: Smoking, Lung Diseases
Interventions: Bronchopulmonary Lung Lavage, Bronchial Brushing, Bronchial Wall Biopsy; Procedure
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 196 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Tobacco Use Disorder, Smoking
Interventions: Ariva Silver Wintergreen, Ariva Wintergreen; Other
Lead sponsor: Star Scientific, Inc; Industry
Eligibility: 23 Years to 72 Years
Enrollment: 37 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009
U.S. locations: 1
States / cities: Martinsburg, West Virginia

Conditions: Cardiovascular Disease, Insulin Resistance
Interventions: Smoking cessation; Behavioral
Lead sponsor: Charles Drew University of Medicine and Science; Other
Eligibility: 25 Years to 70 Years
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Tobacco Use Disorder, Unspecified Adult Solid Tumor, Protocol Specific
Interventions: smoking cessation intervention, counseling intervention; Behavioral · Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 344 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 5
States / cities: Aurora, Colorado • Honolulu, Hawaii • Boston, Massachusetts + 1 more

Conditions: Schizophrenia, Tobacco Use Disorder, Nicotine Dependance
Interventions: Varenicline; Drug
Lead sponsor: Nathan Kline Institute for Psychiatric Research; Other
Eligibility: 18 Years to 65 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: New York, New York

Search by objective public record fields.

Developing E-liquid Product Standards (Sweet Spot Study)

Behavioral Activation Therapy and Nicotine Replacement Therapy in Increasing Smoking Cessation

Effects of Nicotine in Tobacco Smokers

Adaptation and Initial Evaluation of Transdiagnostic CBT for Anxious and Depressed Smokers

Green Tea or Polyphenon E in Preventing Lung Cancer in Former Smokers With Chronic Obstructive Pulmonary Disease

Evaluation of a Novel mHealth Intervention for People Who Are Ambivalent About Quitting Smoking

A Study of Cytisinicline for Smoking Cessation in Adult Smokers

Study to Determine if a New Nicotine Replacement Therapy Can Safely Help Smokers to Quit Smoking

Chest Imaging, Breath, and Biomarkers in a Screening Trial

A Culturally Tailored Smartphone Application for African American Smokers

Effects of Stress and Drug-cue Exposure (SCM)

A Family-Focused Intervention for Asian American Male Smokers

Biomarkers in the Nose, Throat, and Lung Tissue of Smokers and Non-Smokers

Potential Impact of Menthol Ban in Cigarettes and E-cigarettes

Computer-Assisted Counseling in Helping African American Smokers Stop Smoking

Translational Research Center in Lung Cancer Disparities (TRACER) Project 2

Smoking Cessation Pharmacotherapy-Nurse Practitioner Led Tobacco Treatment Team Study

A Study To Investigate The Metabolism Of GW876008 In Smokers Compared To Non-Smokers.

Staccato Loxapine PK in Smokers and Nonsmokers

Evaluation of Lungs of Normal Individuals by Lung Lavage, Brushing and Bronchial Wall Biopsy

A Pilot Study to Evaluate the Efficacy and Safety of Ariva® Silver Wintergreen in Healthy Smokers

Insulin Resistance in Smokers Undergoing Smoking Cessation

Primary Care Physicians' Use of Stop-Smoking Plans to Help Patients Who Are Smokers

Varenicline Effects In Schizophrenic Smokers