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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Speech Disorders Clear all
Enrolling by invitation Not applicable Interventional

Primary Progressive Aphasia Multicomponent Language Treatment Study

NCT06649084
View directory record Official record
Conditions
Primary Progressive Aphasia, Semantic Dementia, Semantic Memory Disorder, Logopenic Progressive Aphasia, Nonfluent Aphasia, Progressive, Aphasia, Aphasia, Progressive
Interventions
Multicomponent Lexical Retrieval Training (Multi-LRT), Multicomponent Video Implemented Script Training in Aphasia (Multi-VISTA), Multicomponent Communication Partner Training (Multi-CPT)
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Recruiting Not applicable Interventional

Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke

NCT06303869
View directory record Official record
Conditions
Stroke, Brain Disease, Central Nervous System Diseases, Nervous System Diseases, Cardiovascular Diseases
Interventions
Deep Brain Stimulation (DBS) of the Motor Thalamus
Device
Lead sponsor
Jorge Gonzalez-Martinez
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jul 22, 2026, 5:04 AM EDT
Recruiting Not applicable Interventional

Using tDCS in Speech-based Stroke Rehabilitation

NCT03452202
View directory record Official record
Conditions
Apraxia of Speech
Interventions
Soterix 1x1 line tDCS low-intensity stimulator, Sham
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 99 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
2
States / cities
New York, New York • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jul 22, 2026, 5:04 AM EDT
Active, not recruiting Phase 2 Interventional

Clinical Study of Neflamapimod in Patients With Primary Progressive Aphasia

NCT07033481
View directory record Official record
Conditions
Nonfluent Variant Primary Progressive Aphasia (nfvPPA)
Interventions
Neflamapimod, Placebo
Drug
Lead sponsor
EIP Pharma Inc
Industry
Eligibility
40 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
5
States / cities
Chicago, Illinois • Rochester, Minnesota • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional

Logoneurosis. Complete Remission. Clinical Document No. 001. Family System CITADEL 2060: METHODOLOGY "VOICE OF SLEEP MAMABEE 2026-2085"

NCT07628114
View directory record Official record
Conditions
Logoneurosis
Interventions
Voice of Sleep MamaBee 2026-2085 Training Modules: Systemic work with brain neurons through training modules at the border of sleep. Restoration of the nervous system core in real time.
Behavioral
Lead sponsor
Pisareva Citadel Group LLC
Other
Eligibility
Not listed
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Framework For Linking Sequential Pattern Rules in DLD: Perception in Toddlers

NCT04531514
View directory record Official record
Conditions
Developmental Language Disorder, Speech Sound Disorder, Specific Language Impairment
Interventions
Sensitivity to phonological rules & referents OR: Toddlers, Sensitivity to phonological rules & referents FR: Toddlers
Other
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
19 Months to 36 Months
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Auditory Prediction and Error Evaluation in the Speech of Individuals Who Stutter

NCT06181149
View directory record Official record
Conditions
Healthy Subjects, Stuttering, Developmental
Interventions
Delaying speech initiation, Auditory errors and pre-speech auditory modulation, Contributions of the speech premotor cortex to pre-speech auditory modulation, Delaying auditory feedback
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
3 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Tempe, Arizona • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 20, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional

Effect of Osteopathic Manipulative Medicine (OMM) on Pulmonary Function and Speech in Parkinson's Disease

NCT01636011
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Osteopathic Manipulative Medicine Treatment, Light Touch sham
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2017 · Synced Jul 22, 2026, 5:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Word Learning From Parentese in Autistic Children

NCT06649916
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder, Neurodevelopmental Disorders
Interventions
Parentese Speech, Adult Registered Speech
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Months to 59 Months
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Recruiting Not applicable Interventional

Characterizing the Impact of Presbyphonia on Social Interaction

NCT06441136
View directory record Official record
Conditions
Presbyphonia
Interventions
PhoRTE Program, University of California Los Angeles (UCLA) Loneliness Scale, Social Disconnectedness Scale, Patient Health Questionnaire 9, Aging Voice Index, The Edmonton Frail Scale, Vocal Effort Scale, Montreal Cognitive Assessment, Voice Handicap Index-10, Voice Problem Impact Scales, Cough Severity Index, Laryngoscopy, Acoustic, perceptual, and aerodynamic assessments
Other · Procedure
Lead sponsor
Matthew R. Hoffman
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural Networks

NCT03153371
View directory record Official record
Conditions
Alzheimer Disease, Early Onset, Alzheimer Disease, Alzheimer Disease, Late Onset, Dementia, Alzheimer Type, Logopenic Progressive Aphasia, Primary Progressive Aphasia, Visuospatial/Perceptual Abilities, Posterior Cortical Atrophy, Executive Dysfunction, Corticobasal Degeneration, Ideomotor Apraxia
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years to 85 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

tACS to Enhance Language Abilities

NCT06092814
View directory record Official record
Conditions
Stroke, Aphasia, Acquired, Aphasia
Interventions
Active transcranial alternating current stimulation (tACS)
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Development of Stuttering in Young Children

NCT06578416
View directory record Official record
Conditions
Stuttering, Stuttering, Childhood, Stuttering, Developmental
Interventions
Standardized assessments of speech and language abilities
Diagnostic Test
Lead sponsor
Michigan State University
Other
Eligibility
3 Years to 6 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computer-Mediated Versus Face-to-Face Motivational-Type Interviews

NCT06945471
View directory record Official record
Conditions
Marijuana Use
Interventions
1) Face-to-face, and 2) Computer-mediated motivational type interviews
Behavioral
Lead sponsor
University of Texas, El Paso
Other
Eligibility
18 Years to 29 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia

NCT06405594
View directory record Official record
Conditions
Aphasia, Acquired, Stroke, Healthy Aging
Interventions
Language Condition
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 2, 2024 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional Results available

Assessing an Animal-Assisted Treatment Program for Adults With Aphasia: The Persons With Aphasia Training Dogs Program

NCT04610346
View directory record Official record
Conditions
Aphasia
Interventions
Persons with Aphasia Training Dogs Program
Behavioral
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
21 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Terminated Phase 3 Interventional Results available

Efficacy and Safety of AM-111 as Acute Sudden Sensorineural Hearing Loss Treatment

NCT02809118
View directory record Official record
Conditions
Hearing Loss, Idiopathic Sudden Sensorineural
Interventions
AM-111 0.4 mg/ml, AM-111 0.8 mg/ml, Placebo
Drug · Other
Lead sponsor
Auris Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
38
States / cities
Birmingham, Alabama • Escondido, California • Fresno, California + 34 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2020 · Synced Jul 22, 2026, 5:04 AM EDT
Terminated Not applicable Interventional

Evaluating the Effectiveness of Hybrid and Traditional Speech Therapy for /ɹ/ and /s/ Sound Production

NCT07061730
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Traditional Therapy, Hybrid therapy
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
5 Years to 17 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 22, 2026, 5:04 AM EDT
Recruiting Not applicable Interventional

Voiceitt for People With Impairments in Speech

NCT06874322
View directory record Official record
Conditions
Speech Impairment, Speech Disorder
Interventions
Voiceitt
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 22, 2026, 5:04 AM EDT
Terminated Phase 4 Interventional Results available

Ketamine-assisted Therapy for Advanced GI Cancer

NCT06077487
View directory record Official record
Conditions
Pancreatic Ductal Adenocarcinoma, Pain, Acute, Gastrointestinal Cancers, Demoralization
Interventions
Ketamine, Ketamine Injectable Product, Meaning and Purpose therapy, Placebo, Questionnaires
Drug · Behavioral · Other
Lead sponsor
Brian Anderson, MD
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional

Venting Effects on Speech Performance

NCT06712693
View directory record Official record
Conditions
Hearing Loss
Interventions
Phonak Audeo Infinio Hearing Aid
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years to 85 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Aurora, Illinois
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Phase 2 Interventional Results available

Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia

NCT03651700
View directory record Official record
Conditions
Aphasia
Interventions
Active TMS, Sham TMS, CILT
Device · Behavioral
Lead sponsor
H. Branch Coslett
Other
Eligibility
18 Years to 80 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Open-canal Behind-the-Ear Hearing Aids and Traditional In-the-ear Hearing Aids.

NCT00727909
View directory record Official record
Conditions
Hearing Loss
Interventions
Hearing Aid Treatments
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years to 85 Years
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
3
States / cities
Bay Pines, Florida • Mountain Home, Tennessee • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 9, 2014 · Synced Jul 22, 2026, 5:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Automated Telephone Outreach With Speech Recognition to Improve Diabetes Care: A Randomized Controlled Study

NCT00790530
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Automated Telephone Outreach with Speech Recognition, Usual Care
Behavioral · Other
Lead sponsor
Harvard Pilgrim Health Care
Other
Eligibility
18 Years and older
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 12, 2008 · Synced Jul 22, 2026, 5:04 AM EDT