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ClinicalTrials.gov public records Last synced Oct 21, 2026, 12:14 PM EDT

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Showing 1–24 of 1,008 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Stenoses Clear all
Completed No phase listed Observational

Balloon Aortic Valvuloplasty During Surgical Aortic Valve Replacement

NCT00584116
View directory record Official record
Conditions
Aortic Stenosis
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 21, 2026, 12:14 PM EDT
Completed No phase listed Observational

Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank

NCT02706639
View directory record Official record
Conditions
Williams Syndrome, Supravalvular Aortic Stenosis, Cardiovascular Disease
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
1 Day to 85 Years
Enrollment
305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
3
States / cities
Bethesda, Maryland • St Louis, Missouri • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 21, 2026, 12:14 PM EDT
Recruiting Not applicable Interventional

COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

NCT02744677
View directory record Official record
Conditions
Complex Congenital Heart Defect, Dysfunctional RVOT Conduit, Pulmonary Valve Insufficiency, Pulmonary Valve Degeneration
Interventions
SAPIEN 3/SAPIEN 3 Ultra RESILIA THV, SAPIEN 3 THV, SAPIEN 3 Ultra RESILIA THV
Device
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
Not listed
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2031
U.S. locations
27
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 21, 2026, 12:14 PM EDT
Terminated No phase listed Observational

Speckle Tracking Imaging in Patients With Low Ejection Fraction Aortic Stenosis (SPArKLE-AS)

NCT00535899
View directory record Official record
Conditions
Aortic Stenosis
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 26, 2008 · Synced Oct 21, 2026, 12:14 PM EDT
Completed Phase 3 Interventional Results available

EPIC Nitinol Stent System in the Treatment of Atherosclerotic Lesions in Iliac Arteries

NCT00896337
View directory record Official record
Conditions
Iliac Artery Stenosis
Interventions
Epic™ Nitinol Stent System, Anti-platelet therapy, Anti-coagulation therapy
Device · Drug
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
28
States / cities
Tucson, Arizona • Brandon, Florida • Fort Lauderdale, Florida + 24 more
Source: ClinicalTrials.gov public record
Updated May 7, 2015 · Synced Oct 21, 2026, 12:14 PM EDT
Completed Not applicable Interventional

Response Inhibition Training for Children With Williams Syndrome

NCT02212314
View directory record Official record
Conditions
Williams Syndrome
Interventions
Response Inhibition Training
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
10 Years to 17 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Oct 21, 2026, 12:14 PM EDT
Terminated Not applicable Interventional

Effectiveness of Lumbar Fusion When NanOss Bioactive Is Used With Posterolateral Gutter Fusions

NCT01452516
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
Interventions
nanOss Bioactive Bone void filler, Interbody FCage
Device
Lead sponsor
Pioneer Surgical Technology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
7
States / cities
Beverly Hills, California • La Jolla, California • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Oct 21, 2026, 12:14 PM EDT
Recruiting No phase listed Observational

RNA Sequencing of Discarded Tracheal Stenosis Tissue to Characterize Cellular and Molecular Pathogenesis

NCT07258784
View directory record Official record
Conditions
Tracheal Stenosis, Subglottic Stenosis
Interventions
Biopsy or surgery
Procedure
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 21, 2026, 12:14 PM EDT
Recruiting Not applicable Interventional

Early Versus Late Endoscopic Stenting for Refractory Benign Esophageal Strictures

NCT06991049
View directory record Official record
Conditions
Refractory Benign Esophageal Strictures
Interventions
Fully covered self-expandable metal esophageal stent
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 21, 2026, 12:14 PM EDT
Terminated No phase listed Observational

Echocardiographic Assessment of Cardiovascular Changes in Long Term Space Flight

NCT00598598
View directory record Official record
Conditions
Aortic Valve Insufficiency, Aortic Valve Stenosis
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Oct 21, 2026, 12:14 PM EDT
Completed Phase 4 Interventional Results available

Lumbar Stenosis Outcomes Research (LUSTOR)

NCT00638443
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Pregabalin, Diphenhydramine
Drug
Lead sponsor
University of Rochester
Other
Eligibility
50 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 20, 2016 · Synced Oct 21, 2026, 12:14 PM EDT
Completed Phase 3 Interventional

Liposomal Bupivacaine To Control Post-Operative Pain Following BMG

NCT03720223
View directory record Official record
Conditions
Urethral Stricture
Interventions
Liposomal Bupivacaine
Drug
Lead sponsor
Urology of Virginia
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Virginia Beach, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 1, 2021 · Synced Oct 21, 2026, 12:14 PM EDT
Completed No phase listed Observational

Effects of Highly Active Anti-Retroviral Therapy on Cardiovascular Health in Infants of HIV-Infected Mothers

NCT00253682
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Atherosclerosis, HIV Infections, Cardiomyopathy, Hypertrophic
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
Up to 2 Years
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
5
States / cities
Miami, Florida • Chicago, Illinois • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 18, 2014 · Synced Oct 21, 2026, 12:14 PM EDT
Enrolling by invitation Phase 4 Interventional

Titanium vs. PEEK Fusion Devices in 1 Level TLIF

NCT05691062
View directory record Official record
Conditions
Spine Fusion, Lumbar Spondylolisthesis, Lumbar Stenosis
Interventions
Titanium Fusion Device, PEEK Fusion Device
Device
Lead sponsor
Twin Cities Spine Center
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Oct 21, 2026, 12:14 PM EDT
Recruiting Not applicable Interventional

Improved Outcomes With Pre-Procedure Shockwave IVL of Common Femoral Artery Access Site Prior to Large Bore Access and Pre-Closure

NCT07205068
View directory record Official record
Conditions
Aortic Stenosis
Interventions
Shockwave M5 IVL Catheter, Modified Seldinger Technique
Device · Procedure
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 21, 2026, 12:14 PM EDT
Completed Phase 1 Interventional

Transcaval Access for Transcatheter Aortic Valve Replacement in People With No Good Options for Aortic Access

NCT02280824
View directory record Official record
Conditions
Aortic Valve Stenosis
Interventions
CA-TAVR, Amplatzer Duct Occluder
Procedure · Device
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years to 99 Years
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
15
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia • Evanston, Illinois + 12 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2019 · Synced Oct 21, 2026, 12:14 PM EDT
Terminated No phase listed Observational

Single Position Spine Surgery Registry

NCT04839783
View directory record Official record
Conditions
Spine Fusion, Spinal Stenosis, Degenerative Disc Disease
Interventions
Not listed
Lead sponsor
Spine and Scoliosis Research Associates
Other
Eligibility
18 Years to 100 Years
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
5
States / cities
Boston, Massachusetts • New York, New York • Wilmington, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 21, 2026, 12:14 PM EDT
Recruiting Early Phase 1 Interventional

68Ga-FAPI-46 PET/CT for Assessing Small Bowel Fibrostenosis in Crohn's Disease

NCT07273188
View directory record Official record
Conditions
Crohn's Disease, Intestinal Fibrosis, Inflamatory Bowel Disease, Intestinal Strictures Related to Crohn´s Disease
Interventions
Ga68-FAPI-46
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 21, 2026, 12:14 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prospective Clinical Evaluation of the New Aegis Plate for Anterior Interbody Fusions

NCT00555659
View directory record Official record
Conditions
Degeneration, Spondylosis, Spondylolithesis, Stenosis
Interventions
Not listed
Lead sponsor
Columbia Orthopaedic Group, LLP
Other
Eligibility
18 Years to 75 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 12, 2013 · Synced Oct 21, 2026, 12:14 PM EDT
Completed Not applicable Interventional Results available

IN.PACT Admiral Drug-Coated Balloon vs. Standard Balloon Angioplasty for the Treatment of Superficial Femoral Artery (SFA) and Proximal Popliteal Artery (PPA)

NCT01566461
View directory record Official record
Conditions
Femoral Artery Stenosis, Popliteal Artery Stenosis, Femoral Artery Occlusion, Popliteal Artery Occlusion
Interventions
Drug-Coated Balloon (DCB), PTA Balloon: Balloon Angioplasty
Device
Lead sponsor
Medtronic Endovascular
Industry
Eligibility
18 Years to 85 Years
Enrollment
331 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Fremont, California • Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Feb 12, 2019 · Synced Oct 21, 2026, 12:14 PM EDT
Completed Not applicable Interventional Results available

Impact of a Corrie Cardiac Rehabilitation Program

NCT05238103
View directory record Official record
Conditions
Coronary Artery Disease, Myocardial Infarction, Myocardial Ischemia, Coronary Artery Occlusion, Coronary Artery Stenosis Stent, Bypass Graft Occlusion, Valve Heart Disease
Interventions
Corrie Hybrid Cardiac Rehabilitation Program
Combination Product
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
259 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 21, 2026, 12:14 PM EDT
Completed No phase listed Observational Results available

Validation of a Computed Tomography (CT) Based Fractional Flow Reserve (FFR) Software Using the 320 Detector Aquilion ONE CT Scanner.

NCT03149042
View directory record Official record
Conditions
Atherosclerosis, Coronary
Interventions
CCTA
Diagnostic Test
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 21, 2026, 12:14 PM EDT
Recruiting No phase listed Observational

Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure

NCT05648474
View directory record Official record
Conditions
Intervertebral Disc Degeneration, Stenosis, Spinal, Spondylolisthesis, Spinal Deformity, Spinal Instability
Interventions
Somatosensory evoked potential [SSEP] intraoperative monitoring
Diagnostic Test
Lead sponsor
Alphatec Spine, Inc.
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Carlsbad, California
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 21, 2026, 12:14 PM EDT
Terminated Not applicable Interventional Results available

NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Early Feasibility Study

NCT06269640
View directory record Official record
Conditions
Hypertrophic Cardiomyopathy, Left Ventricular Septal Hypertrophy, Mitral Valve Disease, Aortic Valve Stenosis
Interventions
Septal Scoring Along Midline Endocardium
Device
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years to 99 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 21, 2026, 12:14 PM EDT