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ClinicalTrials.gov public records Last synced Oct 26, 2026, 10:33 PM EDT

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Showing 1369–1392 of 1,718 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Stress Disorders, Post-Traumatic Clear all
Recruiting Not applicable Interventional

Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTSD

NCT07116109
View directory record Official record
Conditions
Chronic Pain, Post Traumatic Stress Disorder (PTSD)
Interventions
Transcranial Direct Current Stimulation (tDCS), Massed-Prolonged Exposure (PE), Sham Transcranial Direct Current Stimulation (tDCS)
Device · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
21 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Charleston, South Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 26, 2026, 10:33 PM EDT
Completed Not applicable Interventional Results available

Peer-Delivered Whole Health Coaching for Veterans With PTSD

NCT03364192
View directory record Official record
Conditions
PTSD
Interventions
Whole Health Coaching
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced Oct 26, 2026, 10:33 PM EDT
Completed Phase 2 Interventional

Cognitive Behavioral Therapy for Post Traumatic Stress Disorder in Addiction Treatment

NCT01456338
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Substance-Related Disorders
Interventions
Cognitive Behavioral Therapy for PTSD, Individual Addiction Counseling
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
6
States / cities
Hartford, Connecticut • Lebanon, New Hampshire • Manchester, New Hampshire + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2011 · Synced Oct 26, 2026, 10:33 PM EDT
Completed Not applicable Interventional Results available

Addressing the Health Concerns of VA Women With Sexual Trauma

NCT02957747
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Intimate Partner Violence, Alcohol-Related Disorders
Interventions
SHE
Behavioral
Lead sponsor
VISN 17 Center of Excellence
Federal
Eligibility
18 Years to 65 Years · Female only
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Temple, Texas • Waco, Texas
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Oct 26, 2026, 10:33 PM EDT
Terminated Phase 2 Interventional

Cognitive REmediation After Trauma Exposure Trial = CREATE Trial

NCT01416948
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Traumatic Brain Injury
Interventions
Methylphenidate Hydrochloride 20 mg, Placebo Capsule, Galantamine 12 mg
Drug
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
7
States / cities
San Diego, California • Boston, Massachusetts • Manchester, New Hampshire + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2013 · Synced Oct 26, 2026, 10:33 PM EDT
Recruiting Not applicable Interventional

Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)

NCT07060144
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Pregnancy
Interventions
Regular CPT, Massed CPT
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 46 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 26, 2026, 10:33 PM EDT
Completed Not applicable Interventional Results available

Peer Enhanced Prolonged Exposure

NCT02818114
View directory record Official record
Conditions
PTSD
Interventions
Peer Enhanced Prolonged Exposure
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 2, 2019 · Synced Oct 26, 2026, 10:33 PM EDT
Completed Not applicable Interventional Results available

Development of a Patient Centered Mental Health Intervention for Recent Veterans

NCT02943408
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Depression, Anxiety, Substance-Related Disorders
Interventions
person-centered mental health intervention, health and wellness
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
3
States / cities
Baltimore, Maryland • Perry Point, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 26, 2023 · Synced Oct 26, 2026, 10:33 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Acupuncture for Post-Traumatic Stress in Combat Veterans

NCT02871076
View directory record Official record
Conditions
PTSD, Acupuncture, Combat
Interventions
Acupuncture
Device
Lead sponsor
Southern California Institute for Research and Education
Other
Eligibility
18 Years to 55 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2020 · Synced Oct 26, 2026, 10:33 PM EDT
Completed Not applicable Interventional Results available

Mobile Mindfulness to Improve Psychological Distress After Critical Illness

NCT02701361
View directory record Official record
Conditions
Psychological Distress, Depression, Anxiety, Post-traumatic Stress Disorder, Informal Caregivers, Family Members
Interventions
mobile mindfulness, standard mindfulness, education
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Durham, North Carolina • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 7, 2018 · Synced Oct 26, 2026, 10:33 PM EDT
Terminated Not applicable Interventional Results available

Machine Learning Neurofeedback for PTSD

NCT03482466
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Neurofeedback
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 64 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 28, 2024 · Synced Oct 26, 2026, 10:33 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural Dynamics and Connectivity in Response Inhibition and Traumatic Brain Injury

NCT01194661
View directory record Official record
Conditions
Traumatic Brain Injury, Stroke, Headache, PTSD
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 40 Years
Enrollment
129 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 19, 2019 · Synced Oct 26, 2026, 10:33 PM EDT
Not listed Not applicable Interventional

Equine Human Interaction With Veterans

NCT04832815
View directory record Official record
Conditions
PTSD
Interventions
Equine Therapy, Therapeutic Horsemanship Program
Behavioral
Lead sponsor
VA Salt Lake City Health Care System
Federal
Eligibility
18 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 26, 2026, 10:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project QueST 2023: Queer Survivors of Trauma

NCT05569915
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Drinking Heavy
Interventions
Trauma Expressive Writing, Stigma Expressive Writing, Control
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 26, 2026, 10:33 PM EDT
Terminated Not applicable Interventional

Mind-Body Intervention for Veterans With PTSD

NCT02224989
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Mind-Body Bridging
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 75 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 7, 2018 · Synced Oct 26, 2026, 10:33 PM EDT
Completed Not applicable Interventional

Empowering Perinatal Adolescents Through Writing

NCT06771817
View directory record Official record
Conditions
Post-Traumatic Stress Disorder in Adolescence, PTSD - Post Traumatic Stress Disorder, PTSD and Trauma-related Symptoms, Pregnancy and PTSD
Interventions
Written Exposure Therapy
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
15 Years to 24 Years · Female only
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 26, 2026, 10:33 PM EDT
Completed Not applicable Interventional

Treatment for Women With Post-Traumatic Stress Disorder Related to Childhood Abuse

NCT00069381
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Psychotherapy treatment
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
22 Years to 65 Years · Female only
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 29, 2013 · Synced Oct 26, 2026, 10:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Attention Bias Modification Treatment for Warzone-Related Posttraumatic Stress Disorder (PTSD)

NCT01564667
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Attention Bias Modification Training Protocol
Behavioral
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 14, 2016 · Synced Oct 26, 2026, 10:33 PM EDT
Withdrawn Phase 2 Interventional

Trifecta Research Study

NCT06810765
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction, Brain Trauma, Brain Injuries
Interventions
Hormone Replacement Therapy (HRT), Magnetic Resonance Therapy (MeRT), ibogaine with magnesium treatment, 5-MeO-DMT
Other · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 26, 2026, 10:33 PM EDT
Completed Not applicable Interventional

A Case Formulation Approach to Cognitive Processing Therapy

NCT04407767
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Case Formulation plus Cognitive Processing Therapy, Cognitive Processing Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
8
States / cities
Phoenix, Arizona • Honolulu, Hawaii • New Orleans, Louisiana + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 26, 2026, 10:33 PM EDT
Completed Not applicable Interventional Results available

Prolonged Exposure Therapy for PTSD and Opioid Use Disorder

NCT04104022
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Opioid-use Disorder
Interventions
Prolonged Exposure Therapy, Attendance-based monetary incentives
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 26, 2026, 10:33 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder

NCT05516277
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Insomnia, Cardiovascular Diseases, Metabolic Disease
Interventions
Behavioral Sleep Education Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 26, 2026, 10:33 PM EDT
Withdrawn Not applicable Interventional

Expanding and Testing VA Collaborative Care Models for Depression

NCT00119028
View directory record Official record
Conditions
Major Depression, Post-Traumatic Stress Disorder
Interventions
Depression Care Quality Improvement Implementation
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
6
States / cities
Long Beach, California • Shreveport, Louisiana • Minneapolis, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2012 · Synced Oct 26, 2026, 10:33 PM EDT
Completed Phase 2 Interventional

An Evaluation of the Safety and Efficacy of Methylone for the Treatment of PTSD

NCT06215261
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Methylone
Drug
Lead sponsor
Transcend Therapeutics
Industry
Eligibility
18 Years to 70 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
8
States / cities
Lauderhill, Florida • Maitland, Florida • Orlando, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 26, 2026, 10:33 PM EDT