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Showing 1–24 of 505 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Results available

Effect of Oxytocin on Craving and Therapy Response

NCT01827332
View directory record Official record
Conditions
Marijuana Dependence
Interventions
Oxytocin, Saline
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 1, 2017 · Synced Sep 6, 2026, 5:22 AM EDT
Completed Not applicable Interventional Results available

Integrated Treatment for Posttraumatic Stress Disorder and Substance Abuse in Young Adults

NCT02667119
View directory record Official record
Conditions
Substance Use Disorder, Posttraumatic Stress Disorder
Interventions
Prolonged Exposure with Contingency Management, Standard Care
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 25 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
3
States / cities
Farmington, Connecticut • Hartford, Connecticut • New Britain, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 21, 2022 · Synced Sep 6, 2026, 5:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families

NCT06627764
View directory record Official record
Conditions
Substance Abuse, Intimate Partner Violence (IPV), HIV Infections, Depression, Anxiety
Interventions
SER Familia
Behavioral
Lead sponsor
Duke University
Other
Eligibility
12 Years to 100 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 6, 2026, 5:22 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers Results available

The Substance Abuse Treatment to HIV Care II (SAT2HIV-II) Project

NCT04687917
View directory record Official record
Conditions
Substance Use
Interventions
The facilitation, training, feedback, and consultation (FTFC) Strategy, The facilitation, training, feedback, consultation, and incentivization (FTFCI) Strategy
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
428 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Sep 6, 2026, 5:22 AM EDT
Completed Not applicable Interventional Results available

My Pathway to Healing

NCT04585906
View directory record Official record
Conditions
Suicide; Trauma, Binge Drinking
Interventions
Common Elements Treatment Approach
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
25 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Whiteriver, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Sep 6, 2026, 5:22 AM EDT
Completed Not applicable Interventional

Goal Setting for Health Behavior and Psychosocial Issues in Primary Care

NCT01825746
View directory record Official record
Conditions
Health Behaviors, Obesity, Substance Abuse, Anxiety, Depression
Interventions
Implementation of the MOHR assessment in primary care workflow
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 75 Years
Enrollment
3,591 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
8
States / cities
Los Angeles, California • Chapel Hill, North Carolina • Portland, Oregon + 5 more
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Sep 6, 2026, 5:22 AM EDT
Completed No phase listed Observational

A Study on Suicidality, Psychosis or Substance Abuse With Methylphenidate, Atomoxetine, Amphetamine/Dextroamphetamine or Lisdexamfetamine

NCT04132557
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity
Interventions
Methylphenidate, Lisdexamfetamine, Atomoxetine, Amphetamine, Dextroamphetamine
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
Not listed
Enrollment
430,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Titusville, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Sep 6, 2026, 5:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Yappalli - The Road to Choctaw Health

NCT02400554
View directory record Official record
Conditions
Obesity, Substance Abuse
Interventions
Yappalli
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
McAlester, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 2, 2022 · Synced Sep 6, 2026, 5:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interventions for Smoking Among Persons in Recovery

NCT00714896
View directory record Official record
Conditions
Smoking Cessation
Interventions
Stepped-Care, Control
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Walnut Creek, California
Source: ClinicalTrials.gov public record
Updated May 28, 2013 · Synced Sep 6, 2026, 5:22 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Relationship of Adverse Childhood Experiences to Overweight and Obesity

NCT00632346
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Not listed
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 23 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2008 · Synced Sep 6, 2026, 5:22 AM EDT
Completed Phase 1 Interventional

Integrating Interventions for Maternal Substance Abuse

NCT01188434
View directory record Official record
Conditions
Substance Abuse, Child Neglect
Interventions
ITSAN, Services as Usual
Behavioral
Lead sponsor
Oregon Social Learning Center
Other
Eligibility
Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Sep 6, 2026, 5:22 AM EDT
Completed No phase listed Observational Results available

Regional Anesthesia Military Battlefield Pain Outcomes Study

NCT00431847
View directory record Official record
Conditions
Anxiety Disorders, Complex Regional Pain Syndrome Type II, Depressive Disorders, Post-Traumatic Stress Disorder, Substance Abuse
Interventions
Regional Anesthesia, Standard Pain Management Protocol
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
3
States / cities
Bethesda, Maryland • Philadelphia, Pennsylvania • Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Sep 6, 2026, 5:22 AM EDT
Completed Not applicable Interventional Results available

Effect of Oxytocin on Stress in Marijuana Users

NCT01335789
View directory record Official record
Conditions
Marijuana Dependence
Interventions
Oxytocin, Saline
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 13, 2015 · Synced Sep 6, 2026, 5:22 AM EDT
Terminated Not applicable Interventional

Effects of Repeated Memory Training on Memory Function and Addiction Related Processes

NCT03285256
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Experimental memory training, Comparator memory training 1, Comparator memory training 2
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 55 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 9, 2020 · Synced Sep 6, 2026, 5:22 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder

NCT07499583
View directory record Official record
Conditions
Treatment Resistant Depression, Substance Use Disorders
Interventions
Psilocybin
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 6, 2026, 5:22 AM EDT
Completed Phase 1 Interventional

Photobiomodulation to Alter Cerebral Blood Flow and to Affect the Emotional Status of Patients With Major Depression

NCT00961454
View directory record Official record
Conditions
Major Depression, Anxiety Disorder, Post-Traumatic Stress Disorder, Substance Abuse Disorder
Interventions
Photobiomodulation with a super-luminous light emitting diode
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 18, 2009 · Synced Sep 6, 2026, 5:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Youth to Text or Telehealth for Engagement in HIV Care

NCT03681145
View directory record Official record
Conditions
HIV/AIDS, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Depression, Substance Use
Interventions
Counselor delivered telehealth intervention
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 29 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 7, 2025 · Synced Sep 6, 2026, 5:22 AM EDT
Withdrawn Phase 4 Interventional

Comparison of Buprenorphine/Naloxone With Naltrexone in Opioid Dependent Adolescents

NCT01015066
View directory record Official record
Conditions
Opiate Addiction
Interventions
Buprenorphine/naloxone, Naltrexone
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
16 Years to 25 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 9, 2014 · Synced Sep 6, 2026, 5:22 AM EDT
Completed Not applicable Interventional Results available

Women Veterans' Substance Abuse Treatment

NCT00734903
View directory record Official record
Conditions
Substance Use Disorders
Interventions
A Woman's Path to Recovery, 12-Step Facilitation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years · Female only
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
Bedford, Massachusetts • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 4, 2018 · Synced Sep 6, 2026, 5:22 AM EDT
Active, not recruiting Not applicable Interventional

Nexalin Therapy as a Viable Adjunctive Treatment for Substance Use Disorders

NCT03540745
View directory record Official record
Conditions
Depression, Anxiety, Insomnia, Substance Abuse
Interventions
TES Treatment, TES-SHAM Treatment
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Belle Mead, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Sep 6, 2026, 5:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Multi-court Trial of NBP to Prevent Substance Abuse and Mental Health Disorders (MTC)

NCT06132971
View directory record Official record
Conditions
Divorce, Drug Abuse, Mental Health Disorder
Interventions
New Beginnings Program
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
3 Years to 18 Years
Enrollment
2,415 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Sep 6, 2026, 5:22 AM EDT
Completed Not applicable Interventional

Family-Based Treatment for Parental Substance Abuse and Child Maltreatment

NCT01656837
View directory record Official record
Conditions
Substance Abuse, Child Abuse, Child Neglect
Interventions
Comprehensive Community Treatment, MST-BSF
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
6 Years and older
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
New Britain, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 29, 2016 · Synced Sep 6, 2026, 5:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Relapse Prevention With Varenicline

NCT00944554
View directory record Official record
Conditions
Recurrence, Smoking Cessation, Substance-Related Disorders
Interventions
Varenicline, Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 2, 2017 · Synced Sep 6, 2026, 5:22 AM EDT
Completed Not applicable Interventional

Substance Abuse Treatment for High Risk Chronic Pain Patients on Opioid Therapy

NCT00988962
View directory record Official record
Conditions
Substance Abuse
Interventions
cognitive behavioral training
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 26, 2011 · Synced Sep 6, 2026, 5:22 AM EDT