Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 7, 2026, 6:16 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 505 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Abuse Problem Clear all

Conditions: Substance Abuse
Interventions: drug prevention curriculum; Other
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 14 Years to 19 Years
Enrollment: 225 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Health Behaviors, Obesity, Substance Abuse, Anxiety, Depression
Interventions: Implementation of the MOHR assessment in primary care workflow; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 3,591 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 8
States / cities: Los Angeles, California • Chapel Hill, North Carolina • Portland, Oregon + 5 more

Conditions: SAVA
Interventions: Risk-Reduction Sessions; Behavioral
Lead sponsor: University of Maryland, College Park; Other
Eligibility: 18 Years to 49 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: College Park, Maryland

Conditions: Substance Abuse, Substance Addiction, Substance Use Disorder (SUD), Substance Use (Drugs, Alcohol), Human Immunodeficiency Virus (HIV)
Interventions: The TLC Program; Behavioral
Lead sponsor: Illinois Institute of Technology; Other
Eligibility: 18 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Substance Abuse Disorder
Interventions: Low intensity care, Voucher reinforcement; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 223 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Cocaine Addiction, Cocaine Abuse, Cocaine Dependence, Substance Abuse
Interventions: Placebo, Doxazosin; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 55 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Alcohol Dependence
Interventions: Naltrexone 50 Mg, Placebo; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 70 Years
Enrollment: 358 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 2
States / cities: Charleston, South Carolina

Conditions: Substance Use Disorders
Interventions: Recovery Coach Intervention; Behavioral
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years and older
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Posttraumatic Stress Disorder, Substance Use Disorder, Alcohol Use Disorder
Interventions: Creating Change (CC), Seeking Safety (SS); Behavioral
Lead sponsor: VA Boston Healthcare System; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Gram-Positive Bacterial Infections, Gram-Positive Bacteraemia, Substance Use Disorders, Intravenous Substance Abuse
Interventions: Dalbavancin; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: HIV
Interventions: Navigator enhanced case-management, Forensic AIDS Project; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 271 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Neonatal Abstinence Syndrome
Interventions: Stochastic Vibrotactile Stimulation (SVS), Control; Device · Other
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 1 Day to 1 Year
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2019
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Antisocial Behavior
Interventions: Multisystemic Therapy-Emerging Adults, Enhanced Treatment as Usual; Behavioral
Lead sponsor: Chestnut Health Systems; Other
Eligibility: 16 Years to 26 Years
Enrollment: 183 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 4
States / cities: Hamden, Connecticut • Hartford, Connecticut • New Haven, Connecticut + 1 more

Conditions: Substance Use
Interventions: The facilitation, training, feedback, and consultation (FTFC) Strategy, The facilitation, training, feedback, consultation, and incentivization (FTFCI) Strategy; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 428 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Social Harms in Substance Users in HIV Trials, Audio Computer Assisted Self-administered Questionnaire
Interventions: Not listed
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Substance Use Disorders
Interventions: Standard Contingency Management (CM), Enhanced Contingency Management (CM+); Behavioral
Lead sponsor: Oregon Social Learning Center; Other
Eligibility: 12 Years to 18 Years
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Substance Use, Delinquency
Interventions: Miami Juvenile Drug Court-MDFT, Miami Juvenile Drug Court -TAU; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 12 Years to 18 Years
Enrollment: 112 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2009
U.S. locations: 4
States / cities: Miami, Florida

Conditions: Attendance at Treatment, PTSD, Substance Use, and Attendance at Treatment
Interventions: SBIRT; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 346 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 2
States / cities: West Haven, Connecticut • Nashville, Tennessee

Conditions: Heroin Dependence, Opioid-Related Disorders, Substance Abuse, Intravenous
Interventions: Buprenorphine; Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Smoking, Alcohol Abuse, Drug Abuse
Interventions: Self-administered computerized assessment for tobacco, substance abuse, and alcohol use., Self-Administered Computerized Assessment and Counseling for Tobacco, Alcohol, and Substance Abuse; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older
Enrollment: 758 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Substance Use Disorders, Alcohol Abuse, Alcoholism, Substance Dependence, Substance Abuse
Interventions: Contracting, Prompting and Reinforcement arm, Control arm; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 183 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 2
States / cities: Jackson, Mississippi • Salem, Virginia

Conditions: Suicide, Attempted, Substance-Related Disorders
Interventions: Cognitive Therapy, Enriched Care; Behavioral · Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Pre-natal Cocaine Exposure, Risk-Taking
Interventions: fMRI; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 20 Years
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Amphetamine-Related Disorders
Interventions: counseling; Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: Not listed
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 1
States / cities: Los Angeles, California

Search by objective public record fields.

Youth Substance Use Prevention/Reduction Through Science-based Drug Abuse Education

Goal Setting for Health Behavior and Psychosocial Issues in Primary Care

SAVA Syndemic Risk Reduction for African American Couples

The Trans-Led Care Study

Evaluating Three Methods for Helping Syringe Exchangers Begin Methadone Maintenance

The Effects of Doxazosin on the Cardiovascular and Subjective Effects of Cocaine

Genetic and Brain Mechanisms of Naltrexone's Treatment Efficacy for Alcoholism

Inpatient Link to Addiction Recovery

Present- Versus Past-focused Therapy for PTSD and Substance Use Disorder

Substance Use Disorder (SUD)-Associated Infections' Treatment With Dalbavancin ENabling OUtpatient Transition

The Navigator Project

Physiology and Therapeutic Management of Neonatal Abstinence Syndrome

Multisystemic Therapy-Emerging Adults (MST-EA) for Substance Abuse

The Substance Abuse Treatment to HIV Care II (SAT2HIV-II) Project

Improving Identification of Social Harm Among Substance Abusers in HIV Trials

Enhancing Adolescent Substance Abuse Treatment

Family-Based Juvenile Drug Court Services

Evaluation and Treatment of Substance Abuse in Veterans With PTSD Disability Claims

Study of Buprenorphine Maintenance Treatment for Opioid Dependence in Primary Care

Dynamic Assessment and Referral System - Evaluation

Reinforcement of Abstinence and Continuing Care in Substance Abuse Treatment

Effectiveness of Cognitive Therapy for Suicide Attempters With Drug Dependence Disorder

Development of Reward Processing in Prenatally Exposed Adolescents and Young Adults

Cognitive Correlates of Substance Abuse - 11