Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 5:54 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 169–192 of 1,374 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Substance Use Behavior Clear all

Conditions: Pregnancy
Interventions: Not listed
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2027
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Opioid-use Disorder, Opioid-Related Disorders
Interventions: Substance Use Treatment and Recovery Team (START); Behavioral
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 325 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 3
States / cities: Los Angeles, California • Springfield, Massachusetts • Albuquerque, New Mexico

Conditions: Tobacco Use Disorder/Cigarette Smoking
Interventions: Working Memory Training + Behavioral Intervention; Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Tobacco Use Disorder, Smoking
Interventions: Ariva Silver Wintergreen, Ariva Wintergreen; Other
Lead sponsor: Star Scientific, Inc; Industry
Eligibility: 23 Years to 72 Years
Enrollment: 37 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009
U.S. locations: 1
States / cities: Martinsburg, West Virginia

Conditions: Opioid-use Disorder, Opioid-Related Disorders, Alcohol Use Disorder, Alcohol-Related Disorders
Interventions: Substance Use Treatment and Recovery Team (START); Behavioral
Lead sponsor: RAND; Other
Eligibility: 18 Years and older
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Healthy
Interventions: patient-provider interaction; Behavioral
Lead sponsor: Centers for Disease Control and Prevention; Federal
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Tobacco Use Disorder
Interventions: Varying the nicotine content of cigarettes, E-Cigarettes; Other
Lead sponsor: University of Vermont; Other
Eligibility: 21 Years to 44 Years · Female only
Enrollment: 326 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 2
States / cities: Baltimore, Maryland • Burlington, Vermont

Conditions: Anxiety, PTSD, ADHD, Depression Disorders, Post-traumatic Stress, Substance Use, Executive Function, Sleep Disturbance
Interventions: AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation, Audiovisual Entrainment, Vibroacoustic Stimulation, Breathwork-Based Auditory Driving Entropy Module (BADEM), Transcranial Electrical Stimulation; Behavioral · Device
Lead sponsor: Tactical Mind Research Coalition, Inc.; Other
Eligibility: 18 Years to 70 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Cigarette Smoking
Interventions: Contingency Management, Brief smoking cessation counseling; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Smoking, Smoking Cessation, Adherence, Nicotine Dependence, Motivation
Interventions: Short Term Combination Nicotine Replacement Therapy (patch + gum), Long Term Combination Nicotine Replacement Therapy (patch + gum), Intensive Maintenance Counseling, Cognitive Medication Adherence Counseling (CAM), Electronic Medication Monitoring Device (the Helping Hand) + Feedback, Automated Adherence Prompting Phone Calls; Drug · Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 99 Years
Enrollment: 544 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Opioid Use Disorder
Interventions: Youth Opioid Recovery Support (YORS); Behavioral
Lead sponsor: Potomac Health Foundations; Other
Eligibility: 13 Years to 21 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Mental Illness, Substance Use, Criminal Behavior
Interventions: Specialty Mental Health Probation; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 21 Years to 64 Years
Enrollment: 311 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Pregnancy, Substance Use, Depression, Anxiety
Interventions: Listening to Women and Pregnant and Postpartum People; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 41 Years · Female only
Enrollment: 415 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Nicotine Dependence
Interventions: E-cigarettes; Combination Product
Lead sponsor: Duke University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Nicotine Dependence, Tobacco Smoking
Interventions: Normal Nicotine Control Group, Immediate Nicotine Reduction Group, Gradual Nicotine Reduction Group; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 1,250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 10
States / cities: Phoenix, Arizona • San Francisco, California • Tampa, Florida + 7 more

Conditions: Vaping, Nicotine Dependence
Interventions: Double Blind Varenicline, Double Blind Placebo, QuitVaping, This Is Quitting; Drug · Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 16 Years to 25 Years
Enrollment: 261 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pain, Postoperative, Opioid Use Disorder
Interventions: Patient Engagement Tools, Educational Guide; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: HIV, Stigma, Social, Substance Use
Interventions: Ending Self Stigma for Persons living with HIV and Use Substances; Behavioral
Lead sponsor: Friends Research Institute, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Newhall, California • Baltimore, Maryland

Conditions: Depression, Drug Abuse, Sexually Transmitted Diseases
Interventions: Cognitive Behavioral Therapy Development for Methamphetamine Abuse; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years · Male only
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Pediatric Pain, Anxiety, Mood, Stress, Feasibility Studies, Acceptability, Health Promotion, Online Mental Health Program
Interventions: PURSUIT; Behavioral
Lead sponsor: Michigan State University; Other
Eligibility: 8 Years to 18 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Grand Rapids, Michigan

Conditions: Smoking Cessation
Interventions: Telephone counseling, Voucher, Nicotine patches; Behavioral · Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 3,706 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: San Diego, California

Conditions: Parenting, Substance Abuse Relapse, Emotional Regulation
Interventions: DBT Skills + Parent Training; Behavioral
Lead sponsor: University of Oregon; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Substance Use Disorders, Risk Behavior, Psychiatric Disorders, Family Dysfunction
Interventions: Family Therapy based on Structural Family Therapy, Group Therapy, Psychoeducational Sessions, Individual Adolescent Therapy Sessions; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 14 Years to 17 Years
Enrollment: 190 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Alcohol-related Liver Disease, Liver Diseases
Interventions: ENGAGE-ALD Application (APP), Treatment Facilitation bundle, Enhanced Usual Care; Behavioral
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older
Enrollment: 268 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Detroit, Michigan

Search by objective public record fields.

Prenatal Exposure Effects Psychophysiology Study

Substance Use Treatment and Recovery Team

Working Memory Training on Delay Discounting Among Cigarette Smokers

A Pilot Study to Evaluate the Efficacy and Safety of Ariva® Silver Wintergreen in Healthy Smokers

Substance Use Treatment and Recovery Team (START)

Computerized Risk Assessment in an Employee Population

Low Nicotine Content Cigarettes in Vulnerable Populations: Women of Reproductive Age

Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health

Contingency Management for Smoking in Substance Abusers

Evaluation of Treatments to Improve Smoking Cessation Medication Adherence

Expanding the Youth Opioid Recovery Support (YORS) Intervention for MOUD Adherence to Adolescents With OUD

Specialty Mental Health Probation in North Carolina

Pilot Randomized Controlled Trial (RCT): Remote SBIRT Vs. In-Person SBIRT

The Role of Nicotine and Non-Nicotine Alkaloids in E-Cigarette Use and Dependence

Project 2: Strategies for Reducing Nicotine Content in Cigarettes

Varenicline for Nicotine Vaping Cessation in Adolescents

Patient Engagement in Perioperative Pain Management Project

Using the Ending Self-Stigma Intervention to Reduce Internalized Stigma Among People Living With HIV Who Use Substances

Behavioral Therapy Development for Methamphetamine Abuse

PURSUIT: A Technologically Augmented School-based Program to Improve Child Coping and Prevent Substance Use.

Providing Free Nicotine Patches to Quitline Smokers

Integration of DBT Skills and Parent Training for Parents With a History of Substance Use

Culturally Informed Family Based Treatment of Adolescents: A Randomized Trial

Enhancing Alcohol Treatment Engagement in Associated Liver Disease (ALD) Patients