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ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:26 PM EDT

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Showing 1–24 of 194 matching trials from the live ClinicalTrials.gov search.
Conditions
Opioid-use Disorder
Interventions
Mindfulness Oriented Recovery Enhancement Sessions
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Opioid-use Disorder
Interventions
Recovery Initiation and Management after Overdose (RIMO), Passive Referral to Treatment Control
Behavioral · Other
Lead sponsor
Chestnut Health Systems
Other
Eligibility
18 Years and older
Enrollment
251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Addiction, Substance Use Disorders (SUD)
Interventions
Holotropic breathwork, Multiple modality
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lincoln, Nebraska
Conditions
Substance Use Disorder
Interventions
Personal Causal Model + Personalized Feedback
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Alcohol Use Disorder (AUD)
Interventions
Recovery Navigator on an as needed basis up to 6 months, Recovery Navigator prior to hospital discharge, No interaction with Recovery Navigator
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Future Thinking Among Mothers to Reduce Harsh Parenting and Improve Child Outcomes

NCT05229146
Conditions
Behavioral Health
Interventions
Episodic Future Thinking
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
Female only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Flint, Michigan
Conditions
Drug Dependence, Substance Use Disorders
Interventions
Recovery Line
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Bipolar Disorder, Alcohol Use Disorder
Interventions
Adherence therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Alcohol Use Disorder, Alcohol Use Disorder (AUD)
Interventions
STAR
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Madison, Wisconsin
Completed No phase listed Observational Accepts healthy volunteers

Functional Connectivity Changes During Early Recovery as a Marker for Relapse

NCT02861820
Conditions
Substance Use Disorder
Interventions
MRI: Brain Imaging Data Collection
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 45 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Varenicline For Smokers In Recovery From Alcohol Dependence

NCT01092702
Conditions
Tobacco Abstinence
Interventions
Varenicline
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery Study

NCT06074341
Conditions
Alcohol Use Disorder, Alcohol Drinking, Alcohol-Related Disorders
Interventions
Mindfulness-based relapse prevention, Online Mutual Support Groups
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
470 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Albuquerque, New Mexico
Completed Not applicable Interventional Accepts healthy volunteers Results available

Building Recovery By Improving Goals, Habits, and Thoughts

NCT01191788
Conditions
Depression, Substance Use
Interventions
Group Cognitive Behavioral Therapy, Group CBT for Depression
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
299 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Gardena, California
Conditions
Substance Abuse Disorder
Interventions
PRSS (Peer Recovery Support Specialist)
Other
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Morgantown, West Virginia
Conditions
Opioid Use, Prescription Drug Abuse and Dependency, Surgery, Postoperative Pain
Interventions
No opioids at discharge
Behavioral
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Albany, New York
Conditions
Opioid Agonist Treatment, Alcohol Use Disorder, Opioid Use Disorder
Interventions
Digital Contingency Management Intervention Arm, Digital Wellness Arm
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
19 Years to 63 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Accepts healthy volunteers Results available

Project POINT: Effectiveness and Scalability of an Overdose Survivor Intervention

NCT03336268
Conditions
Substance Use Disorders, Overdose
Interventions
POINT
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
249 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Indianapolis, Indiana • Muncie, Indiana
Conditions
Counseling
Interventions
Recovery Guide Counseling
Behavioral
Lead sponsor
Howard University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Not listed Not applicable Interventional

Sleep Treatment for Addiction Recovery

NCT04198311
Conditions
Insomnia, Alcohol Use Disorder, Substance Use Disorders
Interventions
CBT-I
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Active, not recruiting Not applicable Interventional

Mobile Peer Support for OUD Recovery

NCT05405712
Conditions
Opioid Use Disorder
Interventions
Mobile Phone App
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
1,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Indianapolis, Indiana • Providence, Rhode Island
Conditions
Relationship Conflict, Relationship Distress
Interventions
Online Couple Intervention
Behavioral
Lead sponsor
OurRelationship
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
5
States / cities
Marietta, Georgia • Elkton, Maryland • Potsdam, New York + 2 more
Completed Not applicable Interventional

Digitally Assisted Recovery Coach

NCT05393544
Conditions
Alcohol Use Disorder, Alcohol Withdrawal
Interventions
Digitally assisted peer recovery coach
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Active, not recruiting Not applicable Interventional

Stepped Care for Patients to Optimize Whole Recovery

NCT05155163
Conditions
Opioid Use Disorder, Chronic Pain
Interventions
SC-POWR
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
New Haven, Connecticut • North Haven, Connecticut