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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Supplemental Oxygen Clear all
Completed No phase listed Observational

Monitoring of Overdose Patients With and Without Supplemental Oxygen in the Emergency Department

NCT02101424
View directory record Official record
Conditions
Overdose
Interventions
Not listed
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 23, 2014 · Synced Jul 22, 2026, 8:07 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Ergogenic Effects of Sportlegs

NCT06371521
View directory record Official record
Conditions
Performance Enhancing Product Use
Interventions
Sportlegs, Placebo
Dietary Supplement
Lead sponsor
Christopher Bell
Other
Eligibility
18 Years to 30 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Jul 22, 2026, 8:07 PM EDT
Recruiting Phase 2 Interventional

MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes

NCT06930638
View directory record Official record
Conditions
Stroke
Interventions
Ischemic Conditioning, Antioxidant Supplement
Device · Dietary Supplement
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Jul 22, 2026, 8:07 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Safety and Efficacy Trial of Zavegepant* Intranasal for Hospitalized Patients With COVID-19 Requiring Supplemental Oxygen

NCT04346615
View directory record Official record
Conditions
COVID-19 Infection
Interventions
Zavegepant (BHV-3500), Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Philadelphia, Pennsylvania • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 1, 2024 · Synced Jul 22, 2026, 8:07 PM EDT
Completed Not applicable Interventional Results available

Bidirectional Oxygenation Valve in the Management of Pulmonary Complications of COVID-19

NCT04331366
View directory record Official record
Conditions
COVID-19
Interventions
GO2 PEEP MOUTHPIECE
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 17, 2021 · Synced Jul 22, 2026, 8:07 PM EDT
Terminated Phase 2 Interventional Results available

Study to Evaluate the Effect of GBT440 Administered to Subjects With IPF on Supplemental Oxygen at Rest

NCT02989168
View directory record Official record
Conditions
Idiopathic Pulmonary Fibrosis, Hypoxemia
Interventions
GBT440
Drug
Lead sponsor
Global Blood Therapeutics
Industry
Eligibility
45 Years to 85 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
6
States / cities
Birmingham, Alabama • Denver, Colorado • New Orleans, Louisiana + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Jul 22, 2026, 8:07 PM EDT
Not yet recruiting Not applicable Interventional

MOBoxy: MoblO2 to Maintain Oxygenation

NCT07222592
View directory record Official record
Conditions
COPD, Interstitial Lung Disease
Interventions
MoblO2 control
Device
Lead sponsor
National Jewish Health
Other
Eligibility
25 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Jul 22, 2026, 8:07 PM EDT
Completed Not applicable Interventional Results available

Supplemental Oxygen in Colorectal Surgery: A Quality Improvement Project

NCT01777568
View directory record Official record
Conditions
30% Oxygen Concentration During Colorectal Surgery, 80% Oxygen Concentration During Colorectal Surgery
Interventions
30% oxygen, 80% oxygen
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
5,749 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Jul 22, 2026, 8:07 PM EDT
Active, not recruiting Phase 3 Interventional

Strategy to Avoid Excessive Oxygen for Critically Ill Trauma Patients

NCT04534959
View directory record Official record
Conditions
Critical Illness, Wounds and Injury, Disease Attributes, Pathologic Processes
Interventions
Targeting Normoxemia (SpO2 90-96%; PaO2 60-100 mmHg)
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 120 Years
Enrollment
6,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
8
States / cities
Birmingham, Alabama • Denver, Colorado • Cincinnati, Ohio + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Jul 22, 2026, 8:07 PM EDT
Withdrawn Phase 2 Interventional

iNOPulse for COVID-19

NCT04398290
View directory record Official record
Conditions
COVID-19, Hypoxemia, Hypoxemic Respiratory Failure
Interventions
Inhaled nitric oxide (iNO), Nitrogen gas, Oxygen gas
Drug
Lead sponsor
Roger Alvarez
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 18, 2020 · Synced Jul 22, 2026, 8:07 PM EDT
Completed Not applicable Interventional Results available

A Randomized Trial of Outpatient Oxygen Weaning Strategies in Premature Infants

NCT01994954
View directory record Official record
Conditions
Premature Infants
Interventions
RHO
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
Up to 37 Weeks
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
8
States / cities
Farmington, Connecticut • Lexington, Kentucky • Boston, Massachusetts + 5 more
Source: ClinicalTrials.gov public record
Updated May 29, 2023 · Synced Jul 22, 2026, 8:07 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Supplemental Oxygen and the Risk of Surgical Site Infection

NCT00876005
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Oxygen by mask
Other
Lead sponsor
Santa Clara Valley Health & Hospital System
Other
Eligibility
18 Years and older · Female only
Enrollment
1,202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Oct 12, 2016 · Synced Jul 22, 2026, 8:07 PM EDT
Recruiting Phase 4 Interventional

Evaluate the Safety and Feasibility of Same-Day Bilateral Epithelium-On Corneal Cross-Linking for Keratoconus

NCT07629557
View directory record Official record
Conditions
Keratoconus
Interventions
Riboflavin Ophthalmic Solutions, UV-A Irradiation System
Drug · Device
Lead sponsor
Glaukos Corporation
Industry
Eligibility
13 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Westerville, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jul 22, 2026, 8:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Supplemental Oxygen on Memory Testing in Healthy Adult Volunteers

NCT06555484
View directory record Official record
Conditions
Cognition
Interventions
Cross Over Assignment Supplemental Oxygen and Supplemental Air
Device
Lead sponsor
Inogen Inc.
Industry
Eligibility
22 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 30, 2025 · Synced Jul 22, 2026, 8:07 PM EDT
Recruiting Not applicable Interventional

MoblO2 to Maintain Oxygenation

NCT07704567
View directory record Official record
Conditions
COPD (Chronic Obstructive Pulmonary Disease), Intersitital Lung Disease
Interventions
MoblO2 controls O2 flow, MoblO2 does not control flow
Other
Lead sponsor
Minnesota HealthSolutions
Industry
Eligibility
25 Years to 95 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Jul 22, 2026, 8:07 PM EDT
Completed Phase 2 Interventional

A Phase II, Randomized, Double-blind, Placebo-controlled Study to Examine the Effects of DAS181 in Immunocompromised Subjects With Lower Respiratory Tract Parainfluenza Infection on Supplemental Oxygen

NCT01644877
View directory record Official record
Conditions
Parainfluenza
Interventions
DAS181 dry powder, formulation F02, Lactose Placebo
Drug
Lead sponsor
Ansun Biopharma, Inc.
Industry
Eligibility
12 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
45
States / cities
Phoenix, Arizona • Duarte, California • Orange, California + 33 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2017 · Synced Jul 22, 2026, 8:07 PM EDT
Terminated Not applicable Interventional Results available

Supplemental Postoperative Oxygen and Wound Infection in Morbidly Obese Patients

NCT00315822
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
80% oxygen, 30% oxygen
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
2
States / cities
Louisville, Kentucky • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Jul 22, 2026, 8:07 PM EDT
Completed No phase listed Interventional Results available

Validation of Noninvasive Hemoglobin, Comparison of PVI to Standard Methods, and Validation of Clinical Efficacy of ORI

NCT02841397
View directory record Official record
Conditions
Surgery
Interventions
Masimo Pulse CO-Oximeter
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2021 · Synced Jul 22, 2026, 8:07 PM EDT
Completed Not applicable Interventional Results available

Supplemental Oxygen Study

NCT02464917
View directory record Official record
Conditions
Cesarean Section, Supplemental Oxygen, Umbilical Cord Gases
Interventions
Device: simple facemask to administer supplemental oxygen
Device
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2019 · Synced Jul 22, 2026, 8:07 PM EDT
Completed Phase 3 Interventional

Whole Brain Radiation Therapy With Oxygen, With or Without RSR13, in Women With Brain Metastases From Breast Cancer

NCT00083304
View directory record Official record
Conditions
Breast Cancer, Metastases
Interventions
Efaproxiral, Whole Brain Radiation Therapy (WBRT), Supplemental Oxygen
Drug · Radiation · Other
Lead sponsor
Spectrum Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older · Female only
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
39
States / cities
Phoenix, Arizona • Tucson, Arizona • Little Rock, Arkansas + 33 more
Source: ClinicalTrials.gov public record
Updated May 9, 2013 · Synced Jul 22, 2026, 8:07 PM EDT
Completed Phase 4 Interventional Results available

Comparative Effectiveness of a Peer-led O2 Infoline for Patients and Caregivers

NCT02098369
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Written education material (basic), Additional education material, PELICAN-Proactive, PELICAN-Reactive
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
6
States / cities
Lake Forest, California • Torrance, California • Denver, Colorado + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2018 · Synced Jul 22, 2026, 8:07 PM EDT
Completed Not applicable Interventional Results available

Evaluation of a Portable Oxygen Concentrator During Ambulation for Patients Who Require Supplemental Oxygen (POC-LEAN)

NCT04107493
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Portable Oxygen Cylinder, Mobi
Device
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 25, 2021 · Synced Jul 22, 2026, 8:07 PM EDT
Completed Phase 3 Interventional Results available

Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator Testing

NCT00626028
View directory record Official record
Conditions
Idiopathic Pulmonary Arterial Hypertension, Cardiomyopathy
Interventions
Nitric Oxide for inhalation, Oxygen, Nitric Oxide plus Oxygen
Drug
Lead sponsor
Mallinckrodt
Industry
Eligibility
4 Weeks to 18 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
8
States / cities
Stanford, California • Denver, Colorado • Boston, Massachusetts + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2019 · Synced Jul 22, 2026, 8:07 PM EDT