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ClinicalTrials.gov public records Last synced Oct 25, 2026, 10:11 AM EDT

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Showing 745–768 of 1,863 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Surgery-Complications Clear all
Completed No phase listed Observational

Smarter Care Virginia, Examining Low-Value Care in Virginia

NCT04053335
View directory record Official record
Conditions
Chronic Kidney Diseases, Eye Diseases, Cardiac Disease, Surgery, Low Back Pain
Interventions
Multicomponent Physician Performance Peer-Comparison Feedback Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
5,000,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 3, 2023 · Synced Oct 25, 2026, 10:11 AM EDT
Completed No phase listed Observational

Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors

NCT00001668
View directory record Official record
Conditions
Deafness, Kidney Diseases, Kidney Neoplasms, Neoplasms, Retinal Diseases
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 25, 2026, 10:11 AM EDT
Active, not recruiting Phase 2 Interventional

Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer

NCT04576104
View directory record Official record
Conditions
Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia, Endometrial Carcinoma
Interventions
Biopsy Procedure, Extended Release Metformin Hydrochloride, Megestrol Acetate, Questionnaire Administration
Procedure · Drug · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
8
States / cities
Los Angeles, California • Denver, Colorado • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 25, 2026, 10:11 AM EDT
Terminated Not applicable Interventional

Fluid Resuscitation Optimization in Surgical Trauma Patients (FROST)

NCT02742974
View directory record Official record
Conditions
Critical Illness, Trauma
Interventions
Device: FloTrac™ and EV1000™, Volume Challenge, Vasopressor Therapy, Inotropic Therapy
Device · Other · Drug
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 25, 2026, 10:11 AM EDT
Withdrawn Not applicable Interventional

Coordinated Reset Spinal Cord Stimulation

NCT04997278
View directory record Official record
Conditions
Pain, Neuropathic, Failed Back Surgery Syndrome
Interventions
Coordinated Reset spinal cord stimulation
Device
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 8, 2023 · Synced Oct 25, 2026, 10:11 AM EDT
Completed No phase listed Observational

Epidural Analgesia or Patient-Controlled Analgesia in Treating Patients Who Have Undergone Surgery for Gynecologic Cancer

NCT00295945
View directory record Official record
Conditions
Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Ovarian Cancer, Pain, Perioperative/Postoperative Complications, Sarcoma
Interventions
fentanyl citrate, hydromorphone hydrochloride, ropivacaine hydrochloride
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
Female only
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 20, 2014 · Synced Oct 25, 2026, 10:11 AM EDT
Terminated Phase 4 Interventional Results available

Post-Operative Urinary Retention (POUR) in Thoracic Surgery Patients Receiving Prophylactic Tamsulosin

NCT04994431
View directory record Official record
Conditions
Thoracic Diseases, Urinary Retention
Interventions
Tamsulosin Hydrochloride
Drug
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
60 Years and older · Male only
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Oct 25, 2026, 10:11 AM EDT
Completed Phase 2 Interventional Results available

OCS-01 in Treating Inflammation and Pain in Post-cataract Patients

NCT04130802
View directory record Official record
Conditions
Inflammation Corneal, Pain, Postoperative
Interventions
OCS-01 - Dexamethasone Cyclodextrin Nanoparticle Ophthalmic Suspension 1.5% mg/mL, Placebo
Drug
Lead sponsor
Oculis
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
4
States / cities
Petaluma, California • Roseburg, Oregon • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 25, 2026, 10:11 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Opioid Sparing Effect of an ISP Nerve Block on Post-Op Pain Control in Posterior Cervical Spine Surgery

NCT06570577
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Inter-semispinalis Plane Block, Opioids
Procedure · Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 25, 2026, 10:11 AM EDT
Recruiting Not applicable Interventional

Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass

NCT03204357
View directory record Official record
Conditions
Cardiac Disease, Bleeding Postoperative
Interventions
Fresh Autologous whole Blood, Standard of Care Expectant management of bleeding
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Oct 25, 2026, 10:11 AM EDT
Withdrawn Not applicable Interventional

A Mobile Application for Post-op Analgesic Consumption

NCT03197311
View directory record Official record
Conditions
Tooth Extraction Status Nos, Post Operative Pain, Patient Satisfaction, Narcotic Use, Mobile App
Interventions
Mobile app
Other
Lead sponsor
Boston University
Other
Eligibility
18 Years to 40 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2019 · Synced Oct 25, 2026, 10:11 AM EDT
Completed Not applicable Interventional

Wound Dressings For Split-Thickness Skin Graft Donor Sites in Patients Undergoing Surgery

NCT01680367
View directory record Official record
Conditions
Pain, Perioperative/Postoperative Complications
Interventions
wound care management, questionnaire administration
Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 18, 2016 · Synced Oct 25, 2026, 10:11 AM EDT
Terminated Not applicable Interventional Results available

Vaginal Prep Solutions to Reduce Bacteria Colony Counts in Patients Having a Vaginal Surgery

NCT03854370
View directory record Official record
Conditions
Surgical Site Infection, Vaginal Surgery
Interventions
Baby shampoo, Betadine, Peridex, TechniCare
Other
Lead sponsor
Wright State University
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 30, 2024 · Synced Oct 25, 2026, 10:11 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Reducing Hypotensive Anesthesia Use With TXA During Orthognathic Surgery

NCT05474027
View directory record Official record
Conditions
Hypotension During Surgery, Blood Loss, Surgical
Interventions
Avoidance of Deliberate Hypotensive Anesthesia, TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION
Other · Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
12 Years to 75 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 25, 2026, 10:11 AM EDT
Completed Phase 2 Interventional

Self-Hypnotic Relaxation Therapy During Invasive Procedures

NCT00087841
View directory record Official record
Conditions
Uterine Neoplasms, Leiomyoma
Interventions
Self-hypnotic relaxation
Behavioral
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 90 Years
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 17, 2008 · Synced Oct 25, 2026, 10:11 AM EDT
Completed Not applicable Interventional Results available

Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection

NCT01235546
View directory record Official record
Conditions
Endometritis, Wound Infection, Abscess, Surgical Site Infection
Interventions
Azithromycin and standard of care, Placebo and standard of care
Drug
Lead sponsor
Alan Tita
Other
Eligibility
14 Years and older · Female only
Enrollment
2,013 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
9
States / cities
Birmingham, Alabama • New Orleans, Louisiana • Jackson, Mississippi + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2017 · Synced Oct 25, 2026, 10:11 AM EDT
Completed Phase 2Phase 3 Interventional

Cylexin for Reduction of Reperfusion Injury in Infant Heart Surgery

NCT00226369
View directory record Official record
Conditions
Congenital Heart Defects
Interventions
CY-1503
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 45 Days
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2001
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 12, 2010 · Synced Oct 25, 2026, 10:11 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Split Scar Study to Assess Cosmetic Outcome From Differing Suture Spacing

NCT03284983
View directory record Official record
Conditions
Suture, Complication, Wound, Wound Complication, Wound Dehiscence, Wound of Skin, Surgery, Suture; Complications, Infection or Inflammation
Interventions
Suture spacing for wound closure
Other
Lead sponsor
Silver Falls Dermatology
Other
Eligibility
30 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Salem, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 15, 2017 · Synced Oct 25, 2026, 10:11 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Optimal Injection Site for Serratus Anterior Plane Block in Reconstructive Breast Surgery

NCT03183596
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Bupivacaine, Dexamethasone
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 31, 2018 · Synced Oct 25, 2026, 10:11 AM EDT
Not listed Early Phase 1 Interventional

Pain Control and Quality of Recovery After Intravenous Methadone Versus Intrathecal Morphine in Major Abdominal Surgery

NCT06387303
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Methadone, Morphine
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Oct 25, 2026, 10:11 AM EDT
Withdrawn Not applicable Interventional

Breast Reconstruction Following Breast Cancer in Very High Risk Patients

NCT03261323
View directory record Official record
Conditions
Breast Cancer, Malignant Neoplasm of Breast
Interventions
Immediate Breast Reconstruction, Delayed Breast Reconstruction, Breast-Q questionnaire
Procedure · Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
19 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 20, 2022 · Synced Oct 25, 2026, 10:11 AM EDT
Terminated Phase 4 Interventional

Regional Erector Spinae Analgesic Block vs Standard of Care Undergoing Percutaneous Nephrolithotomy

NCT04663269
View directory record Official record
Conditions
Kidney Stone, Surgery
Interventions
4mg PF Dexamethasone, Control Test
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 23, 2021 · Synced Oct 25, 2026, 10:11 AM EDT
Completed No phase listed Observational

Postoperative Pain Reported to Nurses and Physicians

NCT03840356
View directory record Official record
Conditions
Pain, Pain Control, Postoperative Pain
Interventions
Postoperative
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 99 Years
Enrollment
100 participants
Timeline
2018
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 25, 2026, 10:11 AM EDT
Not listed Not applicable Interventional

Surgical Infection Rates With Adjunct Vancomycin Compared to Standard Peri-Operative IV Antibiotics

NCT02299882
View directory record Official record
Conditions
Lumbar Pain
Interventions
Vancomycin
Drug
Lead sponsor
Corewell Health West
Other
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 24, 2014 · Synced Oct 25, 2026, 10:11 AM EDT