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ClinicalTrials.gov public records Last synced Oct 31, 2026, 3:37 PM EDT

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Showing 457–480 of 738 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Swallowing Clear all
Completed Phase 4 Interventional Accepts healthy volunteers

Study of Pantoprazole for Sleepiness Associated With Acid Reflux and Sleep Apnea

NCT00307944
View directory record Official record
Conditions
Acid Reflux Disease, Obstructive Sleep Apnea
Interventions
Pantoprazole
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 12, 2007 · Synced Oct 31, 2026, 3:37 PM EDT
Completed Phase 1 Interventional

Acid Reflux and Stromal Fibroblasts in Barrett's Esophagus

NCT00573911
View directory record Official record
Conditions
Barrett's Esophagus, GERD
Interventions
Endoscopy and pH study
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 17, 2013 · Synced Oct 31, 2026, 3:37 PM EDT
Completed Phase 1 Interventional

Can Quercetin Increase Claudin-4 and Improve Esophageal Barrier Function in GERD?

NCT02226484
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, GERD, Acid Reflux, Reflux
Interventions
Quercetin
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 80 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 20, 2016 · Synced Oct 31, 2026, 3:37 PM EDT
Completed No phase listed Observational Results available

Correlates of GERD Symptom Severity

NCT03020550
View directory record Official record
Conditions
GERD
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 15, 2021 · Synced Oct 31, 2026, 3:37 PM EDT
Completed Phase 3 Interventional Results available

Safety and Quality of Life Study of Dexlansoprazole Modified Release Formulation to Treat Heartburn

NCT00255190
View directory record Official record
Conditions
Gastroesophageal Reflux Disease
Interventions
Dexlansoprazole MR
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years and older
Enrollment
591 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
181
States / cities
Alabaster, Alabama • Anniston, Alabama • Birmingham, Alabama + 178 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2016 · Synced Oct 31, 2026, 3:37 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

A Randomized, Double-Blind, Placebo-Controlled Study of Gastroesophageal Reflux Disease Therapy.

NCT00237068
View directory record Official record
Conditions
Asthma
Interventions
Lansoprazole; Solutab
Drug
Lead sponsor
Emory University
Other
Eligibility
4 Years to 11 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 16, 2011 · Synced Oct 31, 2026, 3:37 PM EDT
Withdrawn No phase listed Observational

Head and Neck Cancer Treatment Related Dysphagia

NCT02657850
View directory record Official record
Conditions
Head and Neck Cancer, Dysphagia
Interventions
non- head and neck self reporting, head neck self reporting, provider reporting
Other
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
6
States / cities
Scottsdale, Arizona • Aurora, Colorado • Rochester, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 18, 2019 · Synced Oct 31, 2026, 3:37 PM EDT
Recruiting Not applicable Interventional

Non-standardized vs. Standardized Screening for Dysphagia

NCT05603897
View directory record Official record
Conditions
Dysphagia
Interventions
Mann Assessment of Swallowing Ability (MASA) (dysphagia screening tool), Non-standardized clinical swallow evaluation
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 31, 2026, 3:37 PM EDT
Not listed No phase listed Observational

Peroral Endoscopic Myotomy (POEM) For The Treatment Of Achalasia: A Registry

NCT02162589
View directory record Official record
Conditions
Achalasia
Interventions
POEM
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 90 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2017 · Synced Oct 31, 2026, 3:37 PM EDT
Completed No phase listed Observational

Review of Infant Oral Feeding and Skills

NCT06736743
View directory record Official record
Conditions
Nutrition Disorders, Gastrointestinal Disease, Deglutition Disorder, Feeding Difficulties, Swallowing Difficulties, Humans, Cohort Studies, Infant, Newborn, Infant, Premature, Nutrition, Pediatric Feeding Disorder, Chronic, Retrospective Studies, Breastfeeding, Mental Health Wellness, Intensive Care Units, Neonatal, Bottle Feeding
Interventions
SMART Tool for Feeding Skill Assessment
Diagnostic Test
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
22 Weeks to 42 Weeks
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 31, 2026, 3:37 PM EDT
Completed Not applicable Interventional

Correlation Between Montreal Cognitive Assessment and Voice Therapy Outcomes in the Aging Treatment- Seeking Population

NCT05187910
View directory record Official record
Conditions
Cognitive Impairment, Voice Disorders, Voicebox Disorders, Cognitive Decline, Swallowing Disorder
Interventions
Speech Therapy, Swallowing Therapy, Upper Airway Therapy
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years to 110 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
4
States / cities
San Francisco, California • Atlanta, Georgia • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 26, 2023 · Synced Oct 31, 2026, 3:37 PM EDT
Completed Not applicable Interventional

Monopolar and Bipolar Current RFA Knife in POEM

NCT05272046
View directory record Official record
Conditions
Esophageal Motility Disorders
Interventions
Per-oral Endoscopic Myotomy, Speedboat (Bipolar electrocautery knife)
Procedure · Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 31, 2026, 3:37 PM EDT
Withdrawn Not applicable Interventional

Functional Luminal Imaging Probe (FLIP) Topography Use in Patients With Scleroderma and Trouble Swallowing

NCT03270722
View directory record Official record
Conditions
Scleroderma, Dysphagia, GERD - Gastro-Esophageal Reflux Disease
Interventions
FLIP topography, Upper Endoscopy
Device · Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2021 · Synced Oct 31, 2026, 3:37 PM EDT
Completed Phase 2Phase 3 Interventional

Pharyngocise Dose Response Study

NCT01279837
View directory record Official record
Conditions
Dysphagia
Interventions
Pharyngocise
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 90 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 5, 2012 · Synced Oct 31, 2026, 3:37 PM EDT
Completed No phase listed Observational

Gastric Bypass After Previous Anti-reflux Surgery

NCT01041105
View directory record Official record
Conditions
Clinically Severe Obesity, Gastroesophageal Reflux Disease
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 60 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Jan 1, 2010 · Synced Oct 31, 2026, 3:37 PM EDT
Completed No phase listed Observational

Esophageal Monitoring Device for Assessing Mucosal Impedance

NCT01556919
View directory record Official record
Conditions
GERD, Esophagitis
Interventions
Standard of care endoscopy
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
429 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Oct 31, 2026, 3:37 PM EDT
Completed Not applicable Interventional Results available

A Pilot Study of Acupuncture Treatment for Dysphagia

NCT00797732
View directory record Official record
Conditions
Carcinomas, Squamous Cell, Dysphagia
Interventions
Acupuncture
Device
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Oct 31, 2026, 3:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study: Manometry With & Without Lidocaine

NCT03349112
View directory record Official record
Conditions
Normal
Interventions
4% Lidocaine Spray, 2% Viscous Lidocaine
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 2, 2019 · Synced Oct 31, 2026, 3:37 PM EDT
Terminated Phase 1 Interventional

Effect of Acid Reflux on Respiratory Physiology During Exercise in Athletes With GER-Response to Acid Suppression

NCT00444236
View directory record Official record
Conditions
Exercise Triggered Asthma, Gastroesophageal Reflux
Interventions
Nexium, Placebo
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 21, 2016 · Synced Oct 31, 2026, 3:37 PM EDT
Withdrawn Not applicable Interventional

Effects of Swallowing Therapy in Head and Neck Cancer

NCT00214305
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
Range of Motion Therapy Program, Postural Sensory Therapy Program
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 2, 2015 · Synced Oct 31, 2026, 3:37 PM EDT
Completed Not applicable Interventional Results available

Lingual Endurance Exercise in Treating Post-Stroke Dysphagia

NCT05523973
View directory record Official record
Conditions
Dysphagia, Oral Phase, Stroke, Ischemic
Interventions
Lingual Endurance Training
Other
Lead sponsor
University of Cincinnati
Other
Eligibility
21 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Oct 31, 2026, 3:37 PM EDT
Completed Phase 2 Interventional

A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD)

NCT00978016
View directory record Official record
Conditions
Gastroesophageal Reflux Disease
Interventions
arbaclofen placarbil-Cohort 1, Placebo-Cohort 5, arbaclofen placarbil-Cohort 2, arbaclofen placarbil-Cohort 3, arbaclofen placarbil-Cohort 4, PPI
Drug
Lead sponsor
XenoPort, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
62
States / cities
Huntsville, Alabama • Chandler, Arizona • Mesa, Arizona + 56 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Oct 31, 2026, 3:37 PM EDT
Recruiting Not applicable Interventional

Respiratory Strength Training in Heart Transplant Recipients

NCT06190171
View directory record Official record
Conditions
Dysphagia, Heart Transplant Recipients
Interventions
Active respiratory muscle strength training, Sham respiratory muscle strength training
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 31, 2026, 3:37 PM EDT
Completed Not applicable Interventional

Anthropometry in Gastroesophageal Reflux Disease and Esophageal Injury

NCT01570842
View directory record Official record
Conditions
Gastroesophageal Reflux Disease (GERD)
Interventions
Anthropometric measurements, Tissue samples
Other · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 31, 2014 · Synced Oct 31, 2026, 3:37 PM EDT