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ClinicalTrials.gov public records Last synced Nov 2, 2026, 5:59 AM EST

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 577–600 of 738 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Swallowing Clear all
Not yet recruiting Not applicable Interventional

Antireflux Surgery Without Preoperative Esophageal Manometry

NCT07659080
View directory record Official record
Conditions
GERD, Hiatal Hernia, Heartburn, Paraesophageal Hernia, Gastroesophageal Reflux
Interventions
Preoperative workup without high-resolution esophageal manometry, Standard preoperative workup with high-resolution esophageal manometry
Procedure
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Nov 2, 2026, 5:59 AM EST
Completed No phase listed Observational

Is the Neosquamous Epithelium "Normal" Following Endoscopic Ablation of Dysplastic Barrett's Esophagus?

NCT01373125
View directory record Official record
Conditions
Barrett's Esophagus, Intestinal Metaplasia, Gastroesophageal Reflux Disease (GERD)
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 80 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced Nov 2, 2026, 5:59 AM EST
Completed Not applicable Interventional Results available

Mechanisms and Management of Infant Dysphagia

NCT02583360
View directory record Official record
Conditions
Dysphagia, Airway Aspiration, Airway Penetration
Interventions
Combined testing (diagnostic VFSS + research HRM) + Parent Preferred Therapy
Diagnostic Test
Lead sponsor
Sudarshan Jadcherla
Other
Eligibility
38 Weeks to 60 Weeks
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 23, 2021 · Synced Nov 2, 2026, 5:59 AM EST
Withdrawn Phase 4 Interventional

A New Nasopharyngeal pH Probe for Diagnosis of Laryngopharyngeal Reflux

NCT01308502
View directory record Official record
Conditions
Laryngopharyngeal Reflux
Interventions
Dx-pH probe
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Month to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2012 · Synced Nov 2, 2026, 5:59 AM EST
Completed Phase 2Phase 3 Interventional Results available

Efficacy and Safety Study of Reslizumab to Treat Eosinophilic Esophagitis in Subjects Aged 5 to 18 Years

NCT00538434
View directory record Official record
Conditions
Eosinophilic Esophagitis
Interventions
Reslizumab, Saline
Biological · Other
Lead sponsor
Ception Therapeutics
Industry
Eligibility
5 Years to 18 Years
Enrollment
227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
34
States / cities
Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 30 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2016 · Synced Nov 2, 2026, 5:59 AM EST
Terminated Not applicable Interventional

Effect of CPAP on Abnormal Gastroesophageal Reflux and Lung Inflammation in IPF

NCT05359965
View directory record Official record
Conditions
Idiopathic Pulmonary Fibrosis, Obstructive Sleep Apnea, Gastro Esophageal Reflux
Interventions
Positive Airway Pressure
Device
Lead sponsor
University of Arizona
Other
Eligibility
50 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Nov 2, 2026, 5:59 AM EST
Completed Phase 2 Interventional Results available

Selective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Disease (GERD)

NCT01472939
View directory record Official record
Conditions
Gastroesophageal Reflux Disease
Interventions
SSP-002358 (0.1 mg) + PPI, SSP-002358 (0.5 mg) + PPI, SSP-002358 (2.0 mg) + PPI, Placebo + PPI
Drug
Lead sponsor
Shire
Industry
Eligibility
18 Years to 70 Years
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
62
States / cities
Phoenix, Arizona • Tucson, Arizona • Little Rock, Arkansas + 58 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2021 · Synced Nov 2, 2026, 5:59 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Structure and Function of the Human Tongue

NCT00007137
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
21 Years to 80 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Nov 2, 2026, 5:59 AM EST
Completed Phase 1 Interventional

Can E-cadherin Found in Tissue/Blood be Valuable in Identifying & Monitoring Patients With Post-proton Pump Inhibitor (PPI)-Responsive Heartburn

NCT01149395
View directory record Official record
Conditions
Heartburn, Gastroesophageal Reflux Disease
Interventions
Dexlansoprazole
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 19, 2016 · Synced Nov 2, 2026, 5:59 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Electrical Muscle Stimulation to Aid Swallowing in Dysphagia

NCT00001936
View directory record Official record
Conditions
Deglutition Disorder, Healthy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Up to 90 Years
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 1999
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Nov 2, 2026, 5:59 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Mucosal Impedance in Pediatric Population

NCT02320981
View directory record Official record
Conditions
Gastroesophageal Reflux Disease (GERD), Eosinophilic Esophagitis (EoE), Functional Dyspepsia
Interventions
Standard of Care esophagogastroduodenoscopy (EGD) with measurement of mucosal impedance
Diagnostic Test
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
1 Year to 18 Years
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 1, 2017 · Synced Nov 2, 2026, 5:59 AM EST
Completed Not applicable Interventional Results available

Efficacy of Electrical Stimulation for Dysphagia in Head & Neck Cancer Patients

NCT00629265
View directory record Official record
Conditions
Dysphagia
Interventions
Neurotech NT2000 Neuromuscular Electrical Stimulation (NMES)
Device
Lead sponsor
Boston Medical Center
Other
Eligibility
21 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
14
States / cities
Scottsdale, Arizona • San Diego, California • Evanston, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2014 · Synced Nov 2, 2026, 5:59 AM EST
Not yet recruiting No phase listed Observational

REVIVE Prospective Registry Cohort Study

NCT07429890
View directory record Official record
Conditions
Oropharyngeal Dysphagia
Interventions
Other: No Intervention (subjects were previously treated with Iltamiocel). This is a observational study and all participants will be observed with no intervention.
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
2
States / cities
Sacramento, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Nov 2, 2026, 5:59 AM EST
Completed Not applicable Interventional Results available

Response to Supplement and Placebo in GERD

NCT01915173
View directory record Official record
Conditions
Gastroesophageal Reflux Disease (GERD), Heartburn, Dyspepsia
Interventions
Supplement, Placebo, Expanded Interview, Standard Interview
Drug · Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Nov 2, 2026, 5:59 AM EST
Completed No phase listed Observational

LMA Cuff Pressure and LMA-induced Complications

NCT01385969
View directory record Official record
Conditions
Sore Throat, Dysphagia, Dysphonia
Interventions
Standard inflation of LMA cuff, Pressure check with syringe recoil, Pressure check by pressure transducer
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 99 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 6, 2015 · Synced Nov 2, 2026, 5:59 AM EST
Completed Phase 3 Interventional

A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Non-Erosive Reflux Disease

NCT05587322
View directory record Official record
Conditions
Non-erosive Reflux Disease
Interventions
BLI5100, Placebo
Drug
Lead sponsor
Braintree Laboratories
Industry
Eligibility
18 Years to 85 Years
Enrollment
788 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
112
States / cities
Huntsville, Alabama • Peoria, Arizona • Phoenix, Arizona + 92 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Nov 2, 2026, 5:59 AM EST
Withdrawn Not applicable Interventional

Confocal Endomicroscopy for Non-Erosive Reflux Disease (CE NERD)

NCT02039869
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Non Erosive Reflux Disease, Dyspepsia
Interventions
Confocal endomicroscopy, Proton pump inhibitor, Sucralfate
Device · Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 79 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
3
States / cities
Kenner, Louisiana • Charleston, South Carolina • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 9, 2015 · Synced Nov 2, 2026, 5:59 AM EST
Withdrawn No phase listed Observational

Correlation of High Resolution Esophageal Manometry With Symptoms

NCT01202929
View directory record Official record
Conditions
Achalasia, Dysphagia, GERD, Chest Pain, Post Fundoplication
Interventions
High Resolution Manometry
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Nov 2, 2026, 5:59 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Eating With Eosinophilic Esophagitis (EoE)

NCT03581838
View directory record Official record
Conditions
Eosinophilic Esophagitis (EoE)
Interventions
Observed eating session
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 9, 2019 · Synced Nov 2, 2026, 5:59 AM EST
Completed No phase listed Observational

To Learn How Bone Structure and Bone Mass Change After Long-term PPI Use

NCT01306799
View directory record Official record
Conditions
Barrett's Esophagus, Erosive Esophagitis, Gastroesophageal Reflux Disease(GERD)
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
40 Years to 75 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2017 · Synced Nov 2, 2026, 5:59 AM EST
Active, not recruiting No phase listed Observational

Long Term Outcomes of Bariatric Patients Treated With Surgery or Endoscopy

NCT03705416
View directory record Official record
Conditions
GERD, Obesity
Interventions
Endoscopy, Surgery
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
250 participants
Timeline
2019 – 2028
U.S. locations
6
States / cities
Baltimore, Maryland • New Hyde Park, New York • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Nov 2, 2026, 5:59 AM EST
Terminated Phase 2 Interventional Results available

Fexofenadine Use in Gastroesophageal Reflux Symptoms

NCT03425097
View directory record Official record
Conditions
Gastroesophageal Reflux
Interventions
Fexofenadine, Placebo - Cap
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 90 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2021 · Synced Nov 2, 2026, 5:59 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Influence of Central Obesity on the Esophageal Epithelial Barrier

NCT02776982
View directory record Official record
Conditions
Gastroesophageal Reflux, GERD
Interventions
Confocal endomicroscopy, Mucosal impedance, Research biopsies, Bravo ambulatory pH monitor
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 9, 2022 · Synced Nov 2, 2026, 5:59 AM EST
Terminated No phase listed Observational

Study of Cryotherapy Treatment of Barrett's Esophagus and Early Esophageal Cancer

NCT00321958
View directory record Official record
Conditions
Barrett Esophagus, Esophageal Neoplasms, Deglutition Disorders, GERD, Neoplasm
Interventions
CSA System (CryoSpray AblationTM System), CryoSpray Ablation
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 8, 2022 · Synced Nov 2, 2026, 5:59 AM EST