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ClinicalTrials.gov public records Last synced Oct 22, 2026, 6:06 AM EDT

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Showing 337–360 of 8,829 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Symptom, Behavioral Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop

NCT03868930
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Traumatic Brain Injury, Substance Related Disorders, Depression, Anxiety Disorders, Suicide, Pain
Interventions
STEP-Home, PCGT
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
221 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Boston, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 22, 2026, 6:06 AM EDT
Active, not recruiting Not applicable Interventional

Deep Brain Stimulation (DBS) Therapy for Treatment Resistant Depression

NCT02046330
View directory record Official record
Conditions
Major Depressive Disorder, Treatment Resistant Depression
Interventions
Deep Brain Stimulation Model 3387 Model 3389
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
22 Years to 70 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 22, 2026, 6:06 AM EDT
Completed Not applicable Interventional Results available

CB3 Pilot (Communication Bridge: A Person-centered Internet-based Intervention for Individuals With Primary Progressive Aphasia)

NCT05697380
View directory record Official record
Conditions
Aphasia, Primary Progressive Aphasia, Dementia, Communication, Alzheimer Disease
Interventions
Communication Bridge™
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 100 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 22, 2026, 6:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Group-based Intervention for Club Patrons

NCT03652688
View directory record Official record
Conditions
Drink Too Much, Drinking, Binge, Drunk, Drug Use, Aggression, Aggression Sexual, Peer Group, Safety Issues, Harm Reduction
Interventions
Nightlife Safety Plans (NSP), Fire Safety
Behavioral
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
21 Years and older
Enrollment
959 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Oct 22, 2026, 6:06 AM EDT
Active, not recruiting Phase 2 Interventional

Novel and Conventional Interventions for Cognitive and Emotional Flexibility in Patient Trauma

NCT07868627
View directory record Official record
Conditions
Depression, Anxiety, Trauma Patients
Interventions
D-Cycloserine (DCS), Transcranial Magnetic Stimulation, Unified Protocol, Psychoeducation
Drug · Device · Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 22, 2026, 6:06 AM EDT
Recruiting Phase 4 Interventional

Examining the Effects of Estradiol on Neural and Molecular Response to Reward

NCT05282277
View directory record Official record
Conditions
Depression, Psychosis, Anhedonia
Interventions
Transdermal Estradiol, Micronized Progesterone, Matching Placebo Patch, Raclopride C11
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
45 Years to 55 Years · Female only
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 22, 2026, 6:06 AM EDT
Completed Phase 2 Interventional Results available

Divalproex Sodium vs. Placebo in Childhood/Adolescent Autism

NCT00211757
View directory record Official record
Conditions
Autism
Interventions
Divalproex sodium, Placebo
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
5 Years to 17 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 28, 2024 · Synced Oct 22, 2026, 6:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Behavioral Parent Training to Address Early Childhood Disruptive Behavior Using the DOCS Parenting Programs

NCT07505381
View directory record Official record
Conditions
Disruptive Behavior, Developmental Disability, Developmental Delay (Disorder), Behavior Problem of Childhood
Interventions
DOCS Parenting: Early Years, DOCS Parenting: School Years
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 22, 2026, 6:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diet, Exercise, Metabolism, and Obesity in Older Women

NCT00664729
View directory record Official record
Conditions
Abdominal Obesity, Metabolic Syndrome
Interventions
Caloric Restriction, Caloric Restriction + Low-Intensity aerobic exercise, Caloric Restriction plus High-intensity aerobic exercise
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
50 Years to 70 Years · Female only
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2008
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Oct 22, 2026, 6:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Antioxidants on Cardiovascular Risk Measures (Spice Study)

NCT00954902
View directory record Official record
Conditions
Cardiovascular, Psychological Stress
Interventions
High Antioxidant Spice Blend, Trier Psychological Stressor, Placebo antioxidant concentrate
Dietary Supplement · Behavioral · Other
Lead sponsor
Penn State University
Other
Eligibility
30 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2018 · Synced Oct 22, 2026, 6:06 AM EDT
Completed Phase 3 Interventional

A Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects With Alzheimer's Disease Agitation

NCT04947553
View directory record Official record
Conditions
Agitation in Patients With Dementia of the Alzheimer's Type, Alzheimer Disease, Agitation, Psychomotor
Interventions
AXS-05 (dextromethorphan-bupropion), Placebo
Drug
Lead sponsor
Axsome Therapeutics, Inc.
Industry
Eligibility
65 Years to 90 Years
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
45
States / cities
Peoria, Arizona • Tempe, Arizona • Long Beach, California + 35 more
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Oct 22, 2026, 6:06 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Fitbit Device Use in Overweight Pregnancy

NCT06226597
View directory record Official record
Conditions
Pregnancy Weight Gain, Overweight and Obesity
Interventions
Fitbit device
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Oct 22, 2026, 6:06 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Communication Strategies to Increase HPV Vaccinations

NCT06784960
View directory record Official record
Conditions
Papilloma Viral Infection, Vaccine Hesitancy, Communication
Interventions
HPV Message 1, HPV Message 2, HPV Message 3, Control Message, Provider Strong-Recommendation Toolkit
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years to 45 Years
Enrollment
9,002 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 22, 2026, 6:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Exercise, Brain Activity, and Weight Maintenance

NCT06511310
View directory record Official record
Conditions
Obesity, Weight Gain, Bariatric Surgery Candidate, Appetitive Behavior
Interventions
Exercise
Other
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Oct 22, 2026, 6:06 AM EDT
Completed Phase 2 Interventional

Mechanistic Evaluation of Response in TRD (MERIT)

NCT04608396
View directory record Official record
Conditions
Treatment Resistant Depression, Major Depressive Disorder
Interventions
AXS-05, Placebo
Drug
Lead sponsor
Axsome Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
20
States / cities
Little Rock, Arkansas • Redlands, California • Sherman Oaks, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2022 · Synced Oct 22, 2026, 6:06 AM EDT
Completed Not applicable Interventional Results available

Psychological Intervention Using Smartphone Technology to Alleviate Malignant Pain

NCT05774197
View directory record Official record
Conditions
Cancer Pain, Opioid Use, Cognitive Behavior Therapy
Interventions
Cognitive Behavioral Therapy for pain
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 22, 2026, 6:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Behavior Therapy for Irritability in Autism

NCT04654260
View directory record Official record
Conditions
Autism Spectrum Disorder, Irritability, Disruptive Behavior, Anger, Aggression, Asperger Syndrome, Pervasive Developmental Disorder
Interventions
Behavioral Therapy for Irritability in Autism, Psychoeducation and Supportive Therapy (PST)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
12 Years to 19 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 22, 2026, 6:06 AM EDT
Recruiting Phase 2 Interventional

A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety

NCT06820723
View directory record Official record
Conditions
Depression, Anxiety, Major Depressive Disorder
Interventions
CYB003, Placebo
Drug
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 22, 2026, 6:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Objective Evaluation of Depression Using Sleep EEG

NCT03133013
View directory record Official record
Conditions
Depression
Interventions
SLEEPSCOPE
Device
Lead sponsor
Stanford University
Other
Eligibility
30 Years to 59 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Oct 22, 2026, 6:06 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

An Evidence-based Approach for Bullying Prevention

NCT03205059
View directory record Official record
Conditions
Bullying, Cyberbullying, Substance Use, Substance Abuse
Interventions
LST MS curriculum+ Bullying/Cyberbulling serious game, LST MS curriculum
Behavioral
Lead sponsor
National Health Promotion Associates, Inc.
Industry
Eligibility
11 Years to 14 Years
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Oct 22, 2026, 6:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Translating a Dementia Caregiver Intervention Into a Mobile Application

NCT04330482
View directory record Official record
Conditions
Dementia, Alzheimer Disease, Caregiver Burnout
Interventions
CARE-Well App, Internet Links
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
Kingston, Rhode Island • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 22, 2026, 6:06 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Open-Label Psilocybin Study in Transdiagnostic Population

NCT06442423
View directory record Official record
Conditions
Transdiagnostic, Depression - Major Depressive Disorder, Anxiety, PTSD Symptoms, PTSD, Substance Use, Substance Use Disorder (SUD), OCD
Interventions
Psilocybin
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 22, 2026, 6:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Exercise Neuroprotection in Parkinson's Disease

NCT05854524
View directory record Official record
Conditions
Parkinson Disease
Interventions
Aerobic exercise
Procedure
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
30 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Oct 22, 2026, 6:06 AM EDT
Completed Not applicable Interventional

Effects of Creatine Supplementation in Breast Cancer Survivors

NCT04207359
View directory record Official record
Conditions
Breast Cancer, Chemotherapy Effect, Muscle Weakness, Muscle Loss, Exercise
Interventions
Creatine
Dietary Supplement
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 25, 2023 · Synced Oct 22, 2026, 6:06 AM EDT