- Conditions
- Traumatic Brain Injury, Acute Brain Injuries
- Interventions
- gammaCore active device, gammaCore sham device
- Device
- Lead sponsor
- CentraCare
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
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Showing 1–24
of 1,249
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Traumatic Brain Injury
- Interventions
- Repetitive Transcranial Magnetic Stimulation
- Device
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Post-Concussion Syndrome, Concussion, Brain, Mild Traumatic Brain Injury, Head Injury, Headache, Dizziness, Cognitive Symptom, Dysautonomia, Anxiety, Irritability; Syndrome, Depression, Post-traumatic Stress Disorder
- Interventions
- Active cTBS, Inactive/Sham cTBS, Imaginal exposure
- Device · Behavioral
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Westwood, Los Angeles, California
- Conditions
- Major Depressive Disorder, Traumatic Brain Injury
- Interventions
- Cognitive Behavioral Therapy for individuals with TBI, Waitlist Control
- Behavioral · Other
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 62 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Tbi, Intracranial Edema, Brain Edema, Craniocerebral Trauma, Head Injury, Brain Hemorrhage, Traumatic, Subdural Hematoma, Brain Concussion, Head Injuries, Closed, Epidural Hematoma, Cortical Contusion, Wounds and Injuries, Disorders of Environmental Origin, Trauma, Nervous System, Brain Injuries
- Interventions
- Therapist Guided Face to Face Family Problem Solving, Therapist Guided Online Family Problem Solving, Self-Guided Online Family Problem Solving
- Behavioral
- Lead sponsor
- Children's Hospital Medical Center, Cincinnati
- Other
- Eligibility
- 14 Years to 19 Years
- Enrollment
- 151 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 5
- States / cities
- Denver, Colorado • Cincinnati, Ohio • Cleveland, Ohio + 1 more
- Conditions
- Brain Injury, Concussion
- Interventions
- Exercise stress test (BCTT)
- Other
- Lead sponsor
- University at Buffalo
- Other
- Eligibility
- 14 Years to 19 Years
- Enrollment
- 54 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Post-Concussion Syndrome, Post-Traumatic Headache, Post-Concussive Syndrome, Chronic, Head Injury, MTBI - Mild Traumatic Brain Injury, Acquired Brain Injury, Closed Head Injury
- Interventions
- Exercise+CT, Exercise only
- Behavioral
- Lead sponsor
- University of Illinois at Urbana-Champaign
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 34 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Urbana, Illinois
- Conditions
- Traumatic Brain Injury
- Interventions
- Implementation Intentions(II)
- Other
- Lead sponsor
- Allina Health System
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Fort Campbell North, Kentucky
- Conditions
- Traumatic Brain Injury
- Interventions
- arginine vasopressin, Standard catecholamine
- Drug
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 96 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2014
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Dementia
- Interventions
- prazosin hydrochloride, placebo
- Drug
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 21 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2023
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Traumatic Brain Injury, Orthopedic Injury
- Interventions
- Not listed
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 3 Years to 18 Years
- Enrollment
- 401 participants
- Timeline
- 2017 – 2024
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Traumatic Brain Injury, Depression
- Interventions
- Duloxetine, Sugar pill
- Drug
- Lead sponsor
- Rehabilitation Hospital of Indiana
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1996 – 2011
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Traumatic Brain Injury
- Interventions
- Delphi-MD device (QuantalX Neuroscience Ltd., Saba Israel)
- Device
- Lead sponsor
- Ramon Diaz-Arrastia
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 215 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Traumatic Brain Injury, Traumatic Encephalopathy
- Interventions
- Ketamine Hydrochloride
- Drug
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Concussion
- Interventions
- Brain 101 website, Control
- Other
- Lead sponsor
- Oregon Center for Applied Science, Inc.
- Industry
- Eligibility
- Not listed
- Enrollment
- 25 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Eugene, Oregon
- Conditions
- Traumatic Brain Injury
- Interventions
- rTMS
- Device
- Lead sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- NIH
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 68 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Traumatic Brain Injury, Cortical Excitability, Epilepsy
- Interventions
- Not listed
- Lead sponsor
- Mid-Atlantic Epilepsy and Sleep Center, LLC
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Mild Traumatic Brain Injury, Post Concussion Syndrome
- Interventions
- Functional near-infrared spectroscopy (fNIRS), V1 stimulation electrodes, Magnetic Resonance Imaging (MRI), MAGNUS scanner
- Device
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 20 Years to 85 Years
- Enrollment
- 55 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Concussion, Mild, Autonomic Nervous System, Cognitive
- Interventions
- Experimental group with 100% intensity setting on Apollo Neuro device, Active Comparator group with 10% intensity setting on the Apollo Neuro device
- Device
- Lead sponsor
- University of South Carolina
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 35 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Columbia, South Carolina
- Conditions
- Traumatic Brain Injury
- Interventions
- Multivitamin Supplement intervention
- Dietary Supplement
- Lead sponsor
- Amen Clinics, Inc.
- Industry
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- Newport Beach, California
- Conditions
- Brain Concussion, Head Injury
- Interventions
- Streak incentive, Loss-based incentive, Flat-fee control status quo condition, Flat-Fitbit control status quo condition
- Behavioral
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 13 Years to 64 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 2
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Concussion, Traumatic Brain Injury
- Interventions
- MRI
- Procedure
- Lead sponsor
- GE Healthcare
- Industry
- Eligibility
- 15 Years to 50 Years
- Enrollment
- 477 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2018
- U.S. locations
- 7
- States / cities
- San Diego, California • San Francisco, California • Miami, Florida + 4 more
- Conditions
- Concussion (Diagnosis)
- Interventions
- Nature-based Guided Awareness Group, Standard Guided Awareness Group
- Behavioral
- Lead sponsor
- Penn State University
- Other
- Eligibility
- 14 Years to 35 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- University Park, Pennsylvania
- Conditions
- Traumatic Brain Injury With Brief Loss of Consciousness, Post-Concussion Syndrome
- Interventions
- Hyperbaric oxygen (HBO2) at 1.5 atms, Sham control 1.2 atms
- Drug
- Lead sponsor
- U.S. Army Medical Research and Development Command
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 71 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 5
- States / cities
- Colorado Springs, Colorado • Fort Carson, Colorado • Jacksonville, North Carolina + 2 more