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Showing 25–39 of 15 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Thermoregulation Clear all
Completed Phase 3 Interventional Accepts healthy volunteers

Intermittent Cold and Dry Air Underneath Football Shoulder Pads

NCT00349804
View directory record Official record
Conditions
Body Temperature Regulation
Interventions
cool dry air
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 11, 2012 · Synced Sep 17, 2026, 6:18 AM EDT
Terminated Not applicable Interventional Results available

The Effect of Convective Pre-warming on Intra-operative Thermoregulatory Capabilities

NCT03876808
View directory record Official record
Conditions
Temperature Change, Body
Interventions
Bair Hugger™ Temperature Management Unit Model 750, 3M™ Bair Paws™ Flex Gown
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 1, 2023 · Synced Sep 17, 2026, 6:18 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Body Temperature in Persons With Tetraplegia When Exposed to Cold

NCT01822535
View directory record Official record
Conditions
Tetraplegia, Hypothermia, Mild Cognitive Impairment
Interventions
Midodrine hydrochloride
Drug
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 68 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Sep 17, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cardiovascular Responses in Burn Survivors During Exercise

NCT06709781
View directory record Official record
Conditions
Burn Injury
Interventions
Control (no cooling modalities), Water Spray
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 17, 2026, 6:18 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Identification of Critical Thermal Environments for Aged Adults

NCT04284397
View directory record Official record
Conditions
Aging
Interventions
Low dose ASA, Control
Drug · Other
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 17, 2026, 6:18 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Role of Menopause in Thermoregulation

NCT06798571
View directory record Official record
Conditions
Menopause, Aging
Interventions
Elagolix Oral Tablet, Estradiol patch, cellulose placebo, placebo patch
Drug · Other
Lead sponsor
Penn State University
Other
Eligibility
42 Years to 64 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 17, 2026, 6:18 AM EDT
Completed Not applicable Interventional

A Novel Noninvasive Thermoregulatory Device for Postural Tachycardia Syndrome

NCT04943276
View directory record Official record
Conditions
Postural Tachycardia Syndrome
Interventions
Embr Device
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Sep 17, 2026, 6:18 AM EDT
Completed Not applicable Interventional

Metabolism and Thyroid Hormone Changes During Exposure to Cold Temperatures

NCT00521729
View directory record Official record
Conditions
Obesity
Interventions
Exposure to Cold Temperature
Procedure
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 60 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2019 · Synced Sep 17, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Validity of CORE Sensor in Heat Training for Male and Female Endurance Athletes

NCT05692947
View directory record Official record
Conditions
Temperature Change, Body
Interventions
Core body temperature device
Device
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 59 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 17, 2026, 6:18 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

AI-Guided Predictions of Blood Pressure Dysregulation Using Perfusion Index as a Novel Biomarker in Persons With Spinal Cord Injury

NCT07699094
View directory record Official record
Conditions
Spinal Cord Injuries (SCI), Blood Pressure, Thermoregulation, Perfusion Index
Interventions
Controlled Cool Thermal Challenge (18°C)
Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 17, 2026, 6:18 AM EDT
Terminated Not applicable Interventional

Weaning Thermoregulatory Support in Preterm Neonates

NCT00769262
View directory record Official record
Conditions
Premature Neonates
Interventions
Conservative weaning, Aggressive Weaning
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
1 Day and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Sep 17, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does Topical Lidocaine Decrease Sweat During Exercise in the Heat?

NCT05379283
View directory record Official record
Conditions
Sweat Pore Closure
Interventions
Lidocaine, control
Drug · Other
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced Sep 17, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Skin Temperature Perception and Prosthetic Thermoregulation

NCT07215442
View directory record Official record
Conditions
Lower Limb Amputation Below Knee, Diabetes (DM), Skin Temperature Change, Vascular Reactivity
Interventions
Warming stimulus starting at 30 C initial temperature, Warming stimulus starting at 32 C initial temperature, Warming stimulus starting at 34 C initial temperature, Warming stimulus starting at 35 C initial temperature, Cooling stimulus starting at 30 C initial temperature, Cooling stimulus starting at 32 C initial temperature, Cooling stimulus starting at 34 C initial temperature, Cooling stimulus starting at 35 C initial temperature
Other
Lead sponsor
VA Puget Sound Health Care System
Federal
Eligibility
18 Years to 70 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Sep 17, 2026, 6:18 AM EDT
Completed Phase 1 Interventional

Study of the Need for Temperature Probe Covers for Newborn Babies on Radiant Warmers

NCT00312065
View directory record Official record
Conditions
Impaired Thermoregulation
Interventions
Application of reflective heat shield to thermistor probe
Device
Lead sponsor
Maimonides Medical Center
Other
Eligibility
Up to 1 Week
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2015 · Synced Sep 17, 2026, 6:18 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Thermoregulation Among Individuals With First-episode Psychosis

NCT04369677
View directory record Official record
Conditions
Psychosis, First Episode Psychosis
Interventions
Not listed
Lead sponsor
Nicholas Breitborde
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 17, 2026, 6:18 AM EDT