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Showing 25–38 of 14 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Early Phase 1 Interventional Accepts healthy volunteers

Does Mirabegron Increase the Body Heat Generated by the Nervous System

NCT06011265
Conditions
Thermoregulation
Interventions
Myrbetriq 25Mg Extended-Release Tablet, Placebo
Drug
Lead sponsor
Christopher Bell
Other
Eligibility
18 Years to 40 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Fort Collins, Colorado
Completed Not applicable Interventional Accepts healthy volunteers

Cardiovascular Responses in Burn Survivors During Exercise

NCT06709781
Conditions
Burn Injury
Interventions
Control (no cooling modalities), Water Spray
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Postural Tachycardia Syndrome
Interventions
Embr Device
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Stanford, California
Completed Not applicable Interventional Accepts healthy volunteers

Does Topical Lidocaine Decrease Sweat During Exercise in the Heat?

NCT05379283
Conditions
Sweat Pore Closure
Interventions
Lidocaine, control
Drug · Other
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
San Diego, California
Conditions
Temperature Change, Body
Interventions
Core body temperature device
Device
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 59 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Eugene, Oregon
Conditions
Premature Neonates
Interventions
Conservative weaning, Aggressive Weaning
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
1 Day and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Anesthesia; Hypothermia, Congenital Heart Disease
Interventions
MRI-safe bore covering
Device
Lead sponsor
Andrew Matisoff
Other
Eligibility
Up to 7 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Not applicable Interventional Accepts healthy volunteers

Skin Temperature Perception and Prosthetic Thermoregulation

NCT07215442
Conditions
Lower Limb Amputation Below Knee, Diabetes (DM), Skin Temperature Change, Vascular Reactivity
Interventions
Warming stimulus starting at 30 C initial temperature, Warming stimulus starting at 32 C initial temperature, Warming stimulus starting at 34 C initial temperature, Warming stimulus starting at 35 C initial temperature, Cooling stimulus starting at 30 C initial temperature, Cooling stimulus starting at 32 C initial temperature, Cooling stimulus starting at 34 C initial temperature, Cooling stimulus starting at 35 C initial temperature
Other
Lead sponsor
VA Puget Sound Health Care System
Federal
Eligibility
18 Years to 70 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers

Cooling Strategies for Older Adults in the Heat

NCT06349616
Conditions
Aging
Interventions
Intermittent cold-water hand and forearm immersion, No intermittent cold-water hand and forearm immersion
Other
Lead sponsor
Penn State University
Other
Eligibility
65 Years to 100 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
University Park, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Energy Expenditure Responses to Different Temperatures

NCT01568671
Conditions
Obesity, Normal Physiology
Interventions
Room temperatures
Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 75 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Temperature Change, Body
Interventions
Bair Hugger™ Temperature Management Unit Model 750, 3M™ Bair Paws™ Flex Gown
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbia, Missouri
Completed No phase listed Observational Accepts healthy volunteers Results available

Observational Examination of Thermoregulation in Total Joint Arthroplasty

NCT02225743
Conditions
Hypothermia
Interventions
Observation Of Temperature
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia

NCT02379156
Conditions
Tetraplegia, Hypothermia, Mild Cognitive Impairment
Interventions
Midodrine Hydrochloride, Cool Temperature
Drug · Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 68 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Impaired Thermoregulation
Interventions
Application of reflective heat shield to thermistor probe
Device
Lead sponsor
Maimonides Medical Center
Other
Eligibility
Up to 1 Week
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Brooklyn, New York