Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 7, 2026, 5:00 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 981 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Tobacco Use Disorders Clear all

Conditions: Marijuana Use, Marijuana Dependence, Tobacco Use, Alcohol Use, Unspecified
Interventions: Domain-Specific Episodic Future Thinking; Behavioral
Lead sponsor: Michael Sofis; Industry
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: Sudbury, Massachusetts

Conditions: Tobacco Use Cessation, Alcohol-related Disorders
Interventions: behavioral counseling plus contingency management; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 151 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 2
States / cities: Newington, Connecticut • West Haven, Connecticut

Conditions: Tobacco Use Disorder
Interventions: Tobacco free snuff; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 70 Years
Enrollment: 138 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Smoking, Smoking Behaviors, Nicotine Dependence
Interventions: E-cigarette with 2.4% Nicotine with Menthol and Tobacco Flavors, E-cigarette with 2.4% Nicotine with Tobacco Flavor Only, E-cigarette with 5% Nicotine with Menthol and Tobacco Flavors, E-cigarette with 5% Nicotine with Tobacco Flavor Only, Tobacco Pouches with 3mg Nicotine with Menthol and Tobacco Flavors, Tobacco Pouches with 3mg Nicotine with Tobacco Flavor Only, Tobacco Pouches with 6mg Nicotine with Menthol and Tobacco Flavors, Tobacco Pouches with 6mg Nicotine with Tobacco Flavor Only; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 21 Years and older
Enrollment: 256 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Alcohol Use Disorder (AUD), Nicotine Use Disorder
Interventions: Contingency Management, Non-contingent control; Behavioral
Lead sponsor: Washington State University; Other
Eligibility: 18 Years and older
Enrollment: 205 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Spokane, Washington

Conditions: Second Hand Tobacco Smoke, Nicotine Dependence
Interventions: Ask, Advise, Refer, Telebased tobacco counseling, Telebased nutrition counseling, Mobile phone smoking cessation application, Mobile phone nutrition application, Nicotine polacrilex; Behavioral · Device · Drug
Lead sponsor: Temple University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 396 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Smoking Cessation, Tobacco Use Disorder
Interventions: nicotine transdermal system; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 55 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: Ends 2005
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Adolescent Substance Use
Interventions: Guiding Good Choices; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 11 Years to 12 Years
Enrollment: 3,636 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2025
U.S. locations: 3
States / cities: Oakland, California • Aurora, Colorado • Detroit, Michigan

Conditions: Lung Cancer Screening, Tobacco Use Disorder, Smoking Cessation
Interventions: Smoking cessation multilevel Intervention; Behavioral
Lead sponsor: Louisiana State University Health Sciences Center in New Orleans; Other
Eligibility: 50 Years to 80 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 2
States / cities: New Orleans, Louisiana

Conditions: Nicotine Dependence, Drug Abuse
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 128 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2011
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Tobacco Use Disorder
Interventions: Persistence Targeted Smoking Cessation, Clearing The Air, Nicotine lozenge; Behavioral · Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 64 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Colon Cancer, Lung Cancer, Tobacco Use Cessation, Obesity, Pneumonia, Bacterial, Shingles, Hepatitis C
Interventions: Epic Healthy Planet Population Health Module; Other
Lead sponsor: University of California, Davis; Other
Eligibility: 50 Years to 80 Years
Enrollment: 20,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Tobacco Use Disorder
Interventions: Behavioral and pharmacologic tobacco use intervention; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Tobacco Dependence
Interventions: Nicotine free cigarettes, Extra-low nicotine cigarettes, Nicotine Lozenge; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 70 Years
Enrollment: 66 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Substance-related Disorders, Depression, High-risk Sex
Interventions: iSBIRT, iSBIRT/TE; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 21 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer, Head and Neck Cancer, Kidney Cancer, Leukemia, Liver Cancer, Lung Cancer, Pancreatic Cancer, Tobacco Use Disorder
Interventions: zinc oxide; Dietary Supplement
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 21 Years to 120 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2015
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Alcohol Abuse, Cannabis Abuse, Nicotine Dependence
Interventions: c-ASBI; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 9 Years to 20 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 6
States / cities: Boston, Massachusetts • Cambridge, Massachusetts • Lexington, Massachusetts

Conditions: Tobacco Use Cessation, Smoking Cessation, Smoking, Tobacco Use Disorder
Interventions: Brief Intervention with NRT Initiation; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 780 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Nicotine Dependence, Pregnancy
Interventions: Biomarker feedback (phone based smoking cessation counseling), Control condition (phone based smoking cessation counseling); Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Anchorage, Alaska

Conditions: Smoking, Nicotine Dependence
Interventions: Nicotine e-cigarette, Non-nicotine e-cigarette; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Tobacco Use Disorder
Interventions: Camel Snus, Marlboro Snus, Stonewall, Ariva, General Snus; Other
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 70 Years
Enrollment: 104 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 2
States / cities: Minneapolis, Minnesota • Eugene, Oregon

Conditions: Prostate Cancer
Interventions: Not listed
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 40 Years to 90 Years · Male only
Enrollment: 2,033 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2020
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Smoking Cessation, Smoking, Tobacco, Mental Illness, Tobacco Use Disorder
Interventions: Videogame-based physical activity, Sedentary videogame, Bupropion, Counseling; Behavioral · Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Alcohol Abuse, Nicotine Dependence Tobacco Product
Interventions: E-cig use; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 21 Years and older
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Indianapolis, Indiana

Search by objective public record fields.

Examining Effects of Domain Specific Episodic Future Thinking on Cannabis Use

Concurrent Alcohol and Smoking Treatment: Effects on Alcohol Relapse Risk

Effectiveness of Using Tobacco Free Snuff in Reducing Negative Effects of Smokeless Tobacco Use

Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction

Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking

Babies Living Safe and Smokefree

Effectiveness of the Nicotine Patch in Suppressing Nicotine Withdrawal Symptoms in Women Versus Men - 1

Guiding Good Choices for Health

Multilevel Intervention for LDCT Lung Cancer Screening and Smoking Cessation Among African Americans

Effects of Nicotine on Brain Activity as Measured by fMRI

Persistence-Targeted Smoking Cessation

Enhancing Electronic Health Systems to Decrease the Burden of Colon Cancer, Lung Cancer, Obesity, Vaccine-Preventable Illness, and LivER Cancer

Tobacco Use Intervention Among Radiation Oncology Patients

Comparisons of Nicotine-free Cigarettes, Extra Low Nicotine Cigarettes vs. Medicinal Nicotine

Primary Care iSBIRT to Reduce Serious Teen Health Risks

Zinc Supplements in Lowering Cadmium Levels in Smokers

Trial of Computerized SBI to Reduce Teen Alcohol Use

Treating Low-Income Smokers in the Hospital Emergency Department

Biomarker Feedback to Motivate Cessation in Pregnancy

Short Term Effects of Electronic Cigarettes in Tobacco Dependent Adults

Evaluation of Oral Tobacco as a Harm Reduction Method for Smokers

An Epidemiological Study of Genetic Risk Factors for Prostate Cancer in African-American and Caucasian Males

PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness

Reactions to E-cigs and Alcohol